Non-alcoholic steatohepatitis in a Japanese obese child

Non-alcoholic steatohepatitis in a Japanese obese child

A 10-year-old boy was referred to our hospital because of liver dysfunction. His body mass index was 29.7; however, other physical findings were normal. He did not have any history of illness and was not taking any medication. His parents were obese and had fatty liver disease, but no hypertension or diabetes. His laboratory data were as follows: total bilirubin, 0.6 (normal range (NR) 0.3–1.2) mg/dL; aspartate aminotransferase, 253 (NR 14–33) IU/L; alanine aminotransferase, 588 (NR 3–20) IU/L; γ-glutamyl transferase, 186 (NR 7–23) IU/L; total cholesterol, 222 (NR 140–199) mg/dL; low-density lipoprotein, 151 (NR 60–119) mg/dL and triglyceride, 134 (NR 30–149) mg/dL. Abdominal ultrasonography (US) and abdominal CT revealed fatty liver, but no evidence of chronic hepatitis or …

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