{"id":9269,"date":"2024-01-24T12:38:52","date_gmt":"2024-01-24T09:38:52","guid":{"rendered":"https:\/\/urbancare.clinic\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\/"},"modified":"2024-01-24T12:38:52","modified_gmt":"2024-01-24T09:38:52","slug":"je-vidonge-vya-insulini-vilivyopakwa-chokoleti-vinaweza-kuchukua-nafasi-ya-sindano-utafiti-wa-wanyama-unaonyesha-matokeo-ya-kuahidi-kwa-wagonjwa-wa-kisukari","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\/","title":{"rendered":"Je, Vidonge vya Insulini Vilivyopakwa Chokoleti Kuchukua Nafasi ya Sindano? Utafiti wa Wanyama Huonyesha Matokeo Yenye Kuahidi Kwa Wagonjwa wa Kisukari"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p>Je, kuna njia mbadala isiyo na maumivu ya risasi za insulini? Habari njema zinaweza kuwa karibu sana watu walio na ugonjwa wa kisukari, kwani matokeo ya uchunguzi wa hivi karibuni wa wanyama yanaonyesha kuwa kidonge cha insulini kinachoweza kumezwa kilichowekwa kwenye kipande cha chokoleti kinaweza kuchukua nafasi ya risasi chungu za insulini katika siku zijazo.<\/p>\n<p>Takriban watu milioni 425 duniani wana kisukari na milioni 75 kati yao wanategemea sindano za insulini kudhibiti viwango vyao vya sukari kwenye damu.<\/p>\n<p>Wanasayansi kutoka Chuo Kikuu cha Troms\u00f8 (UiT) Chuo Kikuu cha Aktiki cha Norwe waligundua njia mbadala za upigaji insulini na wakatengeneza kidonge kilichowekwa ndani chenye vibeba nano-vya insulini vilivyoundwa kwa ajili ya utoaji wa moja kwa moja kwenye ini.<\/p>\n<p>&quot;Njia hii ya kuchukua insulini ni sahihi zaidi kwa sababu hupeleka insulini haraka kwenye maeneo ya mwili ambayo yanahitaji zaidi. Unapotumia insulini kwa kutumia sindano, husambaa mwili mzima ambapo inaweza kusababisha madhara yasiyotakikana,\u201d <a rel=\"noopener nofollow\" href=\"https:\/\/uit.no\/nyheter\/artikkel?p_document_id=836727\" target=\"_blank\">sema<\/a> Peter McCourt kutoka UiT Chuo Kikuu cha Arctic cha Norway, mtafiti nyuma ya utafiti uliochapishwa katika jarida la Nature Nanotechnology.<\/p>\n<p>Tofauti na dawa nyingi zinazoweza kumezwa, insulini lazima idungwe, kwani huvunjika tumboni kabla ya kufika kwenye ini. Walakini, watafiti walitatua kikwazo hicho kwa kuunda mipako ya kinga ambayo inaweza tu kuvunja ini wakati viwango vya sukari ya damu viko juu.<\/p>\n<p>&quot;Tumeunda mipako ili kulinda insulini isivunjwe na asidi ya tumbo na vimeng&#039;enya vya usagaji chakula kwenye njia ya mfumo wa usagaji chakula, kuiweka salama hadi ifike mahali inapoenda, yaani ini,&quot; McCourt alielezea.<\/p>\n<p>&quot;Hii ina maana kwamba wakati sukari ya damu iko juu, kuna kutolewa kwa haraka kwa insulini, na muhimu zaidi wakati sukari ya damu iko chini, hakuna insulini inayotolewa,&quot; alisema Nicholas J. Hunt kutoka Chuo Kikuu cha Sydney, mtafiti ambaye alishirikiana. aliongoza mradi.<\/p>\n<p>&quot;Ili kufanya insulini ya mdomo ipendeke tuliiingiza kwenye chokoleti isiyo na sukari, mbinu hii ilipokelewa vyema,&quot; Hunt aliongeza.<\/p>\n<p>Kulingana na Hunt, vidonge vinatoa njia ya vitendo zaidi na ya kirafiki ya kudhibiti ugonjwa wa kisukari na kupunguza hatari ya hypoglycemia. Mbinu hiyo inaruhusu kutolewa kwa insulini kudhibitiwa kulingana na mahitaji ya mgonjwa, tofauti na sindano ambapo insulini yote hutolewa kwa risasi moja.<\/p>\n<p>Watafiti walisema mbinu ya utoaji wa insulini ya kidonge inafanya kazi sawa na jinsi insulini inavyofanya kazi kwa watu wenye afya nzuri na itakuwa na athari chache.<\/p>\n<p>&quot;Unapoingiza insulini chini ya ngozi na sindano, nyingi zaidi huenda kwenye misuli na kwenye tishu za adipose ambayo kawaida hufanyika ikiwa itatolewa kutoka kwa kongosho, ambayo inaweza kusababisha mkusanyiko wa mafuta. Inaweza pia kusababisha hypoglycemia, ambayo inaweza kuwa hatari kwa watu wenye ugonjwa wa kisukari. Kwa njia mpya, kutakuwa na madhara machache kama hayo. Kwa kuongeza, huna haja ya kujichoma na sindano na unaweza kuchukua dawa unayohitaji kwa njia ya busara zaidi. Pia, aina hii ya insulini haihitaji kuwekwa kwenye jokofu,\u201d watafiti walisema.<\/p>\n<p>Insulini ya mdomo imejaribiwa kwa nematodes, panya na panya ambao wana ugonjwa wa kisukari. Katika jaribio la hivi majuzi, watafiti waliwajaribu kwenye nyani 20 wenye afya nzuri na wakagundua kuwa wamepunguza viwango vya sukari kwenye damu.<\/p>\n<p>Majaribio ya wanadamu yataanza mnamo 2025, na watafiti wanatumai dawa hiyo mpya inaweza kupatikana kwa matumizi katika miaka miwili hadi mitatu.<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-suggests-promising-results-471302\">Chanzo cha matibabu cha kila siku<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients.jpg\" class=\"ff-og-image-inserted\"><\/div>\n<p>Je, kuna njia mbadala isiyo na maumivu ya risasi za insulini? Habari njema zinaweza kuwa karibu sana watu walio na ugonjwa wa kisukari, kwani matokeo ya uchunguzi wa hivi karibuni wa wanyama yanaonyesha kuwa kidonge cha insulini kinachoweza kumezwa kilichowekwa kwenye kipande cha chokoleti kinaweza kuchukua nafasi ya risasi chungu za insulini katika siku zijazo.<\/p>\n<p>Takriban watu milioni 425 duniani wana kisukari na milioni 75 kati yao wanategemea sindano za insulini kudhibiti viwango vyao vya sukari kwenye damu.<\/p>\n<p>Wanasayansi kutoka Chuo Kikuu cha Troms\u00f8 (UiT) Chuo Kikuu cha Aktiki cha Norwe waligundua njia mbadala za upigaji insulini na wakatengeneza kidonge kilichowekwa ndani chenye vibeba nano-vya insulini vilivyoundwa kwa ajili ya utoaji wa moja kwa moja kwenye ini.<\/p>\n<p>&quot;Njia hii ya kuchukua insulini ni sahihi zaidi kwa sababu hupeleka insulini haraka kwenye maeneo ya mwili ambayo yanahitaji zaidi. Unapotumia insulini kwa kutumia sindano, husambaa mwili mzima ambapo inaweza kusababisha madhara yasiyotakikana,\u201d <a rel=\"noopener nofollow\" href=\"https:\/\/uit.no\/nyheter\/artikkel?p_document_id=836727\" target=\"_blank\">sema<\/a> Peter McCourt kutoka UiT Chuo Kikuu cha Arctic cha Norway, mtafiti nyuma ya utafiti uliochapishwa katika jarida la Nature Nanotechnology.<\/p>\n<p>Tofauti na dawa nyingi zinazoweza kumezwa, insulini lazima idungwe, kwani huvunjika tumboni kabla ya kufika kwenye ini. Walakini, watafiti walitatua kikwazo hicho kwa kuunda mipako ya kinga ambayo inaweza tu kuvunja ini wakati viwango vya sukari ya damu viko juu.<\/p>\n<p>&quot;Tumeunda mipako ili kulinda insulini isivunjwe na asidi ya tumbo na vimeng&#039;enya vya usagaji chakula kwenye njia ya mfumo wa usagaji chakula, kuiweka salama hadi ifike mahali inapoenda, yaani ini,&quot; McCourt alielezea.<\/p>\n<p>&quot;Hii ina maana kwamba wakati sukari ya damu iko juu, kuna kutolewa kwa haraka kwa insulini, na muhimu zaidi wakati sukari ya damu iko chini, hakuna insulini inayotolewa,&quot; alisema Nicholas J. Hunt kutoka Chuo Kikuu cha Sydney, mtafiti ambaye alishirikiana. aliongoza mradi.<\/p>\n<p>&quot;Ili kufanya insulini ya mdomo ipendeke tuliiingiza kwenye chokoleti isiyo na sukari, mbinu hii ilipokelewa vyema,&quot; Hunt aliongeza.<\/p>\n<p>Kulingana na Hunt, vidonge vinatoa njia ya vitendo zaidi na ya kirafiki ya kudhibiti ugonjwa wa kisukari na kupunguza hatari ya hypoglycemia. Mbinu hiyo inaruhusu kutolewa kwa insulini kudhibitiwa kulingana na mahitaji ya mgonjwa, tofauti na sindano ambapo insulini yote hutolewa kwa risasi moja.<\/p>\n<p>Watafiti walisema mbinu ya utoaji wa insulini ya kidonge inafanya kazi sawa na jinsi insulini inavyofanya kazi kwa watu wenye afya nzuri na itakuwa na athari chache.<\/p>\n<p>&quot;Unapoingiza insulini chini ya ngozi na sindano, nyingi zaidi huenda kwenye misuli na kwenye tishu za adipose ambayo kawaida hufanyika ikiwa itatolewa kutoka kwa kongosho, ambayo inaweza kusababisha mkusanyiko wa mafuta. Inaweza pia kusababisha hypoglycemia, ambayo inaweza kuwa hatari kwa watu wenye ugonjwa wa kisukari. Kwa njia mpya, kutakuwa na madhara machache kama hayo. Kwa kuongeza, huna haja ya kujichoma na sindano na unaweza kuchukua dawa unayohitaji kwa njia ya busara zaidi. Pia, aina hii ya insulini haihitaji kuwekwa kwenye jokofu,\u201d watafiti walisema.<\/p>\n<p>Insulini ya mdomo imejaribiwa kwa nematodes, panya na panya ambao wana ugonjwa wa kisukari. Katika jaribio la hivi majuzi, watafiti waliwajaribu kwenye nyani 20 wenye afya nzuri na wakagundua kuwa wamepunguza viwango vya sukari kwenye damu.<\/p>\n<p>Majaribio ya wanadamu yataanza mnamo 2025, na watafiti wanatumai dawa hiyo mpya inaweza kupatikana kwa matumizi katika miaka miwili hadi mitatu.<\/p>","protected":false},"author":2,"featured_media":9270,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9269","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Can Chocolate-Coated Insulin Pills Replace Needles? Animal Study Shows Promising Results For Diabetes Patients - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/je-vidonge-vya-insulini-vilivyopakwa-chokoleti-vinaweza-kuchukua-nafasi-ya-sindano-utafiti-wa-wanyama-unaonyesha-matokeo-ya-kuahidi-kwa-wagonjwa-wa-kisukari\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Can Chocolate-Coated Insulin Pills Replace Needles? Animal Study Shows Promising Results For Diabetes Patients - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Is there a pain-free alternative to insulin shots? Good news might be on the horizon for people with diabetes, as findings of a recent animal study suggest that a swallowable insulin pill tucked in a piece of chocolate might replace painful insulin shots in the future.Around 425 million people in the world have diabetes and 75 million of them depend on insulin injections to manage their blood sugar levels.Scientists from the University of Troms\u00f8 (UiT) The Arctic University of Norway explored alternatives to insulin shots and developed an encapsulated pill with tiny nano-carriers of insulin designed for direct delivery to the liver.&quot;This way of taking insulin is more precise because it delivers the insulin rapidly to the areas of the body that need it most. When you take insulin with a syringe, it is spread throughout the body where it can cause unwanted side effects,&quot; said Peter McCourt from UiT The Arctic University of Norway, a researcher behind the study published in the journal Nature Nanotechnology.Unlike many medicines that can be swallowed, insulin has to be injected, as it breaks down in the stomach before it reaches the liver. However, researchers solved the hurdle by creating a protective coating that can only break down in the liver when the blood sugar levels are high.&quot;We have created a coating to protect the insulin from being broken down by stomach acid and digestive enzymes on its way through the digestive system, keeping it safe until it reaches its destination, namely the liver,&quot; McCourt explained.&quot;This means that when blood sugar is high, there is a rapid release of insulin, and even more importantly when blood sugar is low, no insulin is released,&quot; said Nicholas J. Hunt from the University of Sydney, a researcher who co-led the project.&quot;In order to make the oral insulin palatable we incorporated it into sugar-free chocolate, this approach was well received,&quot; Hunt added.According to Hunt, the pills offer a more practical and patient-friendly method of managing diabetes and reduce the risk of hypoglycemia. The technique allows the controlled release of insulin based on the patient&#039;s requirements, unlike injections where all the insulin is released in one shot.The researchers said the pill&#039;s insulin delivery technique works similarly to how insulin works in healthy people and will have fewer side effects.&quot;When you inject insulin under the skin with a syringe, far more of it goes to the muscles and to adipose tissues that would normally happen if it was released from the pancreas, which can lead to the accumulation of fats. It can also lead to hypoglycemia, which can potentially be dangerous for people with diabetes. With the new method, there will be fewer such side effects. In addition, you do not need to stab yourself with a needle and you can take the medicine you need in a slightly more discreet way. Also, this form of insulin does not need to be refrigerated,&quot; the researchers said.The oral insulin has been tested on nematodes, mice and rats that have diabetes. In a recent trial, researchers tested them on 20 healthy baboons and found them to have reduced blood sugar levels.The human trials will begin in 2025, and researchers hope the new medicine could be available for use in two to three years.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/sw\/je-vidonge-vya-insulini-vilivyopakwa-chokoleti-vinaweza-kuchukua-nafasi-ya-sindano-utafiti-wa-wanyama-unaonyesha-matokeo-ya-kuahidi-kwa-wagonjwa-wa-kisukari\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2024-01-24T09:38:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"dakika 3\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Can Chocolate-Coated Insulin Pills Replace Needles? 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Utafiti wa Wanyama Unaonyesha Matokeo Yenye Kuahidi Kwa Wagonjwa wa Kisukari - Kliniki ya Huduma ya Mjini","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/sw\/je-vidonge-vya-insulini-vilivyopakwa-chokoleti-vinaweza-kuchukua-nafasi-ya-sindano-utafiti-wa-wanyama-unaonyesha-matokeo-ya-kuahidi-kwa-wagonjwa-wa-kisukari\/","og_locale":"en_US","og_type":"article","og_title":"Can Chocolate-Coated Insulin Pills Replace Needles? Animal Study Shows Promising Results For Diabetes Patients - Urban Care Clinic","og_description":"Is there a pain-free alternative to insulin shots? Good news might be on the horizon for people with diabetes, as findings of a recent animal study suggest that a swallowable insulin pill tucked in a piece of chocolate might replace painful insulin shots in the future.Around 425 million people in the world have diabetes and 75 million of them depend on insulin injections to manage their blood sugar levels.Scientists from the University of Troms\u00f8 (UiT) The Arctic University of Norway explored alternatives to insulin shots and developed an encapsulated pill with tiny nano-carriers of insulin designed for direct delivery to the liver.\"This way of taking insulin is more precise because it delivers the insulin rapidly to the areas of the body that need it most. When you take insulin with a syringe, it is spread throughout the body where it can cause unwanted side effects,\" said Peter McCourt from UiT The Arctic University of Norway, a researcher behind the study published in the journal Nature Nanotechnology.Unlike many medicines that can be swallowed, insulin has to be injected, as it breaks down in the stomach before it reaches the liver. However, researchers solved the hurdle by creating a protective coating that can only break down in the liver when the blood sugar levels are high.\"We have created a coating to protect the insulin from being broken down by stomach acid and digestive enzymes on its way through the digestive system, keeping it safe until it reaches its destination, namely the liver,\" McCourt explained.\"This means that when blood sugar is high, there is a rapid release of insulin, and even more importantly when blood sugar is low, no insulin is released,\" said Nicholas J. Hunt from the University of Sydney, a researcher who co-led the project.\"In order to make the oral insulin palatable we incorporated it into sugar-free chocolate, this approach was well received,\" Hunt added.According to Hunt, the pills offer a more practical and patient-friendly method of managing diabetes and reduce the risk of hypoglycemia. The technique allows the controlled release of insulin based on the patient's requirements, unlike injections where all the insulin is released in one shot.The researchers said the pill's insulin delivery technique works similarly to how insulin works in healthy people and will have fewer side effects.\"When you inject insulin under the skin with a syringe, far more of it goes to the muscles and to adipose tissues that would normally happen if it was released from the pancreas, which can lead to the accumulation of fats. It can also lead to hypoglycemia, which can potentially be dangerous for people with diabetes. With the new method, there will be fewer such side effects. In addition, you do not need to stab yourself with a needle and you can take the medicine you need in a slightly more discreet way. Also, this form of insulin does not need to be refrigerated,\" the researchers said.The oral insulin has been tested on nematodes, mice and rats that have diabetes. In a recent trial, researchers tested them on 20 healthy baboons and found them to have reduced blood sugar levels.The human trials will begin in 2025, and researchers hope the new medicine could be available for use in two to three years.","og_url":"https:\/\/urbancare.clinic\/sw\/je-vidonge-vya-insulini-vilivyopakwa-chokoleti-vinaweza-kuchukua-nafasi-ya-sindano-utafiti-wa-wanyama-unaonyesha-matokeo-ya-kuahidi-kwa-wagonjwa-wa-kisukari\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2024-01-24T09:38:52+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Urban Care Clinic","Est. reading time":"dakika 3"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/can-chocolate-coated-insulin-pills-replace-needles-animal-study-shows-promising-results-for-diabetes-patients\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"Can Chocolate-Coated Insulin Pills Replace Needles? 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