{"id":9220,"date":"2023-12-29T08:10:06","date_gmt":"2023-12-29T05:10:06","guid":{"rendered":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/"},"modified":"2023-12-29T08:10:06","modified_gmt":"2023-12-29T05:10:06","slug":"mbinu-mbadala-ya-kutibu-fetma-wanasayansi-kuendeleza-vibrating-capsule-kumezwa-ambayo-inakufanya-kujisikia-kamili","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/","title":{"rendered":"Njia Mbadala ya Kutibu Unene? Wanasayansi Hukuza Kibonge Cha Kutetemeka, Kinachomeza Ambacho Hukufanya Ujisikie Kamili"},"content":{"rendered":"
<\/div>\n

Watafiti wameunda kapsuli inayoweza kumeza, ambayo inapomezwa kabla ya mlo, hutetemeka tumboni, na kutuma ishara kwa ubongo ili kuunda hisia ya uwongo ya kujaa na kuidanganya kuacha kula. Kifurushi kipya kinaweza kuibuka kama njia isiyo na uvamizi na ya gharama nafuu ya kutibu unene.<\/p>\n

Watafiti kutoka Taasisi ya Teknolojia ya Massachusetts kupimwa<\/a> kidonge kipya kwa wanyama na kugundua kuwa kilipopewa dakika 20 kabla ya kula, kilichochea kutolewa kwa homoni zinazoashiria shibe na kupunguza ulaji wa chakula cha mnyama kwa takriban 40%. Matokeo yalichapishwa katika jarida la Sayansi ya Maendeleo.<\/p>\n

"Kwa mtu ambaye anataka kupunguza uzito au kudhibiti hamu ya kula, inaweza kuchukuliwa kabla ya kila mlo. Hii inaweza kuwa ya kufurahisha sana kwa kuwa itatoa chaguo ambalo linaweza kupunguza athari ambazo tunaona na matibabu mengine ya kifamasia huko nje," mwandishi kiongozi Shriya Srinivasan, kutoka Chuo Kikuu cha Harvard, alisema katika taarifa ya habari<\/a>.<\/p>\n

Kunywa glasi ya maji kabla ya chakula hukufanya uhisi njaa kidogo. Hii ni kwa sababu wakati tumbo limejaa kioevu, mechanoreceptors ya bitana ya tumbo hutuma ishara kwa ubongo, na kukufanya uhisi kushiba. Watafiti walifanya kazi juu ya wazo hili na wakajaribu ikiwa kibonge cha kumeza ambacho kinatetemeka ndani ya tumbo kinaweza kunyoosha mechanoreceptors na kuunda hisia sawa ya ukamilifu.<\/p>\n

"Tumbo linapokuwa limetandazwa, chembe maalumu zinazoitwa mechanoreceptors huhisi kwamba kunyoosha na kutuma ishara kwa ubongo kupitia neva ya uke. Matokeo yake, ubongo huchochea uzalishaji wa insulini, pamoja na homoni kama vile C-peptide, Pyy na GLP-1. Homoni hizi zote hufanya kazi pamoja ili kusaidia watu kusaga chakula chao, kujisikia kushiba, na kuacha kula. Wakati huo huo, viwango vya ghrelin, homoni ya kukuza njaa, hupungua, "watafiti walielezea.<\/p>\n

Timu ya utafiti ilitengeneza kibonge chenye ukubwa wa multivitamini, inayoendeshwa na betri ndogo ya oksidi ya fedha. Baada ya capsule kumeza, maji ya tumbo hufuta utando unaoifunika, kukamilisha mzunguko wa umeme na kuamsha motor vibrating.<\/p>\n

Wakati wa majaribio ya wanyama, watafiti waligundua kuwa kifaa kilipokuwa kitetemeka, viwango vya homoni viliiga kwa karibu mifumo inayoonekana baada ya mlo wa kawaida. Hakukuwa na dalili za kizuizi, utoboaji au athari zingine mbaya kwa wanyama wakati kidonge kikiwa kwenye njia ya usagaji chakula. Vidonge vilipitia njia ya utumbo ndani ya siku nne au tano.<\/p>\n

Toleo la sasa la kidonge linaweza kutetemeka kwa takriban dakika 30 baada ya kufikia tumbo. Watafiti wanapanga kurefusha kwa muda mrefu na kujaribu uwezekano wa kuiwasha na kuiwasha bila waya.<\/p>\n

Watafiti wanatumai kidonge kipya kinaweza kufanya kazi kama mbadala salama kwa njia za sasa za kutibu unene wakati lishe na mazoezi yanashindwa. Afua nyingi zilizopo za matibabu kama vile upasuaji wa njia ya utumbo na puto za tumbo mara nyingi huchukuliwa kuwa vamizi na hazipendekezwi sana kwa sababu ya maswala ya usalama. Ingawa dawa kama agonists za GLP-1 zinaweza kusaidia kupunguza uzito, nyingi zinahitaji sindano, na kuzifanya kuwa rahisi na zisizoweza kununuliwa kwa wengi.<\/p>\n

"Kwa watu wengi, baadhi ya matibabu ya ufanisi zaidi ya fetma ni ya gharama kubwa. Kwa ukubwa, kifaa chetu kinaweza kutengenezwa kwa bei ya bei nafuu. Ningependa kuona jinsi hii inaweza kubadilisha utunzaji na matibabu kwa watu katika mazingira ya afya ya kimataifa ambao wanaweza kukosa ufikiaji wa chaguzi za kisasa zaidi au za gharama kubwa ambazo zinapatikana leo," Srinivasan alisema.<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Watafiti wameunda kapsuli inayoweza kumeza, ambayo inapomezwa kabla ya mlo, hutetemeka tumboni, na kutuma ishara kwa ubongo ili kuunda hisia ya uwongo ya kujaa na kuidanganya kuacha kula. Kifurushi kipya kinaweza kuibuka kama njia isiyo na uvamizi na ya gharama nafuu ya kutibu unene.<\/p>\n

Watafiti kutoka Taasisi ya Teknolojia ya Massachusetts kupimwa<\/a> kidonge kipya kwa wanyama na kugundua kuwa kilipopewa dakika 20 kabla ya kula, kilichochea kutolewa kwa homoni zinazoashiria shibe na kupunguza ulaji wa chakula cha mnyama kwa takriban 40%. Matokeo yalichapishwa katika jarida la Sayansi ya Maendeleo.<\/p>\n

"Kwa mtu ambaye anataka kupunguza uzito au kudhibiti hamu ya kula, inaweza kuchukuliwa kabla ya kila mlo. Hii inaweza kuwa ya kufurahisha sana kwa kuwa itatoa chaguo ambalo linaweza kupunguza athari ambazo tunaona na matibabu mengine ya kifamasia huko nje," mwandishi kiongozi Shriya Srinivasan, kutoka Chuo Kikuu cha Harvard, alisema katika taarifa ya habari<\/a>.<\/p>\n

Kunywa glasi ya maji kabla ya chakula hukufanya uhisi njaa kidogo. Hii ni kwa sababu wakati tumbo limejaa kioevu, mechanoreceptors ya bitana ya tumbo hutuma ishara kwa ubongo, na kukufanya uhisi kushiba. Watafiti walifanya kazi juu ya wazo hili na wakajaribu ikiwa kibonge cha kumeza ambacho kinatetemeka ndani ya tumbo kinaweza kunyoosha mechanoreceptors na kuunda hisia sawa ya ukamilifu.<\/p>\n

"Tumbo linapokuwa limetandazwa, chembe maalumu zinazoitwa mechanoreceptors huhisi kwamba kunyoosha na kutuma ishara kwa ubongo kupitia neva ya uke. Matokeo yake, ubongo huchochea uzalishaji wa insulini, pamoja na homoni kama vile C-peptide, Pyy na GLP-1. Homoni hizi zote hufanya kazi pamoja ili kusaidia watu kusaga chakula chao, kujisikia kushiba, na kuacha kula. Wakati huo huo, viwango vya ghrelin, homoni ya kukuza njaa, hupungua, "watafiti walielezea.<\/p>\n

Timu ya utafiti ilitengeneza kibonge chenye ukubwa wa multivitamini, inayoendeshwa na betri ndogo ya oksidi ya fedha. Baada ya capsule kumeza, maji ya tumbo hufuta utando unaoifunika, kukamilisha mzunguko wa umeme na kuamsha motor vibrating.<\/p>\n

Wakati wa majaribio ya wanyama, watafiti waligundua kuwa kifaa kilipokuwa kitetemeka, viwango vya homoni viliiga kwa karibu mifumo inayoonekana baada ya mlo wa kawaida. Hakukuwa na dalili za kizuizi, utoboaji au athari zingine mbaya kwa wanyama wakati kidonge kikiwa kwenye njia ya usagaji chakula. Vidonge vilipitia njia ya utumbo ndani ya siku nne au tano.<\/p>\n

Toleo la sasa la kidonge linaweza kutetemeka kwa takriban dakika 30 baada ya kufikia tumbo. Watafiti wanapanga kurefusha kwa muda mrefu na kujaribu uwezekano wa kuiwasha na kuiwasha bila waya.<\/p>\n

Watafiti wanatumai kidonge kipya kinaweza kufanya kazi kama mbadala salama kwa njia za sasa za kutibu unene wakati lishe na mazoezi yanashindwa. Afua nyingi zilizopo za matibabu kama vile upasuaji wa njia ya utumbo na puto za tumbo mara nyingi huchukuliwa kuwa vamizi na hazipendekezwi sana kwa sababu ya maswala ya usalama. Ingawa dawa kama agonists za GLP-1 zinaweza kusaidia kupunguza uzito, nyingi zinahitaji sindano, na kuzifanya kuwa rahisi na zisizoweza kununuliwa kwa wengi.<\/p>\n

"Kwa watu wengi, baadhi ya matibabu ya ufanisi zaidi ya fetma ni ya gharama kubwa. Kwa ukubwa, kifaa chetu kinaweza kutengenezwa kwa bei ya bei nafuu. Ningependa kuona jinsi hii inaweza kubadilisha utunzaji na matibabu kwa watu katika mazingira ya afya ya kimataifa ambao wanaweza kukosa ufikiaji wa chaguzi za kisasa zaidi au za gharama kubwa ambazo zinapatikana leo," Srinivasan alisema.<\/p>","protected":false},"author":2,"featured_media":9221,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9220","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nAn Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/mbinu-mbadala-ya-kutibu-fetma-wanasayansi-kuendeleza-vibrating-capsule-kumezwa-ambayo-inakufanya-kujisikia-kamili\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Researchers have developed an ingestible capsule, which when ingested before a meal, vibrates in the stomach, sending signals to the brain to create an illusory sense of fullness and trick it to stop eating. The new capsule could emerge as a minimally invasive and cost-effective way to treat obesity.Researchers from the Massachusetts Institute of Technology tested the new capsule on animals and found that when given 20 minutes before eating, it stimulated the release of hormones that signal satiety and reduced the animal's food intake by about 40%. The results were published in the journal Science Advances."For somebody who wants to lose weight or control their appetite, it could be taken before each meal. This could be really interesting in that it would provide an option that could minimize the side effects that we see with the other pharmacological treatments out there," lead author Shriya Srinivasan, from Harvard University, said in a news release.Drinking a glass of water before a meal makes you feel less hungry. This is because when the stomach is full of liquid, the mechanoreceptors of the stomach lining send signals to the brain, making you feel satiated. Researchers worked on this idea and tested if an ingestible capsule that vibrates within the stomach could artificially stretch the mechanoreceptors and create the same sense of fullness."When the stomach becomes distended, specialized cells called mechanoreceptors sense that stretching and send signals to the brain via the vagus nerve. As a result, the brain stimulates the production of insulin, as well as hormones such as C-peptide, Pyy and GLP-1. All of these hormones work together to help people digest their food, feel full, and stop eating. At the same time, levels of ghrelin, a hunger-promoting hormone, go down," researchers explained.The research team designed a capsule about the size of a multivitamin, powered by a small silver oxide battery. After the capsule gets ingested, the gastric fluids dissolve the membrane that covers it, complete the electronic circuit and activate the vibrating motor.During animal trials, researchers noticed that when the device was vibrating, hormone levels closely mimicked the patterns seen after a regular meal. There were no signs of obstruction, perforation or other negative impacts in animals while the pill was in their digestive tract. The pills passed through the digestive tract within four or five days.The current version of the pill can vibrate for about 30 minutes after reaching the stomach. Researchers plan to extend it for longer periods and test the possibility of activating and deactivating it wirelessly.Researchers hope the new pill could work as a safer alternative to the current methods of treating obesity when diet and exercise fail. Many existing medical interventions such as gastric bypass surgery and gastric balloons are often considered invasive and are not widely recommended due to safety concerns. While drugs like GLP-1 agonists can help in weight loss, many of them require injection, making them less convenient and unaffordable for many."For a lot of populations, some of the more effective therapies for obesity are very costly. At scale, our device could be manufactured at a pretty cost-effective price point. I'd love to see how this would transform care and therapy for people in global health settings who may not have access to some of the more sophisticated or expensive options that are available today," Srinivasan said.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/sw\/mbinu-mbadala-ya-kutibu-fetma-wanasayansi-kuendeleza-vibrating-capsule-kumezwa-ambayo-inakufanya-kujisikia-kamili\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-29T05:10:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"dakika 3\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"An Alternative Approach To Treat Obesity? 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Wanasayansi Watengeneza Kibonge cha Mtetemo, Kimeza ambacho Hukufanya Ujisikie Kamili - Kliniki ya Utunzaji wa Mijini","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/sw\/mbinu-mbadala-ya-kutibu-fetma-wanasayansi-kuendeleza-vibrating-capsule-kumezwa-ambayo-inakufanya-kujisikia-kamili\/","og_locale":"en_US","og_type":"article","og_title":"An Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic","og_description":"Researchers have developed an ingestible capsule, which when ingested before a meal, vibrates in the stomach, sending signals to the brain to create an illusory sense of fullness and trick it to stop eating. The new capsule could emerge as a minimally invasive and cost-effective way to treat obesity.Researchers from the Massachusetts Institute of Technology tested the new capsule on animals and found that when given 20 minutes before eating, it stimulated the release of hormones that signal satiety and reduced the animal's food intake by about 40%. The results were published in the journal Science Advances.\"For somebody who wants to lose weight or control their appetite, it could be taken before each meal. This could be really interesting in that it would provide an option that could minimize the side effects that we see with the other pharmacological treatments out there,\" lead author Shriya Srinivasan, from Harvard University, said in a news release.Drinking a glass of water before a meal makes you feel less hungry. This is because when the stomach is full of liquid, the mechanoreceptors of the stomach lining send signals to the brain, making you feel satiated. Researchers worked on this idea and tested if an ingestible capsule that vibrates within the stomach could artificially stretch the mechanoreceptors and create the same sense of fullness.\"When the stomach becomes distended, specialized cells called mechanoreceptors sense that stretching and send signals to the brain via the vagus nerve. As a result, the brain stimulates the production of insulin, as well as hormones such as C-peptide, Pyy and GLP-1. All of these hormones work together to help people digest their food, feel full, and stop eating. At the same time, levels of ghrelin, a hunger-promoting hormone, go down,\" researchers explained.The research team designed a capsule about the size of a multivitamin, powered by a small silver oxide battery. After the capsule gets ingested, the gastric fluids dissolve the membrane that covers it, complete the electronic circuit and activate the vibrating motor.During animal trials, researchers noticed that when the device was vibrating, hormone levels closely mimicked the patterns seen after a regular meal. There were no signs of obstruction, perforation or other negative impacts in animals while the pill was in their digestive tract. The pills passed through the digestive tract within four or five days.The current version of the pill can vibrate for about 30 minutes after reaching the stomach. Researchers plan to extend it for longer periods and test the possibility of activating and deactivating it wirelessly.Researchers hope the new pill could work as a safer alternative to the current methods of treating obesity when diet and exercise fail. Many existing medical interventions such as gastric bypass surgery and gastric balloons are often considered invasive and are not widely recommended due to safety concerns. While drugs like GLP-1 agonists can help in weight loss, many of them require injection, making them less convenient and unaffordable for many.\"For a lot of populations, some of the more effective therapies for obesity are very costly. At scale, our device could be manufactured at a pretty cost-effective price point. I'd love to see how this would transform care and therapy for people in global health settings who may not have access to some of the more sophisticated or expensive options that are available today,\" Srinivasan said.","og_url":"https:\/\/urbancare.clinic\/sw\/mbinu-mbadala-ya-kutibu-fetma-wanasayansi-kuendeleza-vibrating-capsule-kumezwa-ambayo-inakufanya-kujisikia-kamili\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-12-29T05:10:06+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Urban Care Clinic","Est. reading time":"dakika 3"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"An Alternative Approach To Treat Obesity? 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