{"id":8643,"date":"2023-09-15T13:20:23","date_gmt":"2023-09-15T10:20:23","guid":{"rendered":"https:\/\/urbancare.clinic\/us-surgeons-report-longest-successful-pig-to-human-kidney-transplant\/"},"modified":"2023-09-15T13:20:23","modified_gmt":"2023-09-15T10:20:23","slug":"madaktari-wetu-wa-upasuaji-wanaripoti-nguruwe-aliyefaulu-kwa-muda-mrefu-zaidi-kwa-upandikizaji-wa-figo-za-binadamu","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/madaktari-wetu-wa-upasuaji-wanaripoti-nguruwe-aliyefaulu-kwa-muda-mrefu-zaidi-kwa-upandikizaji-wa-figo-za-binadamu\/","title":{"rendered":"Madaktari wa Upasuaji wa Marekani Waripoti Upandikizaji wa Figo wa Nguruwe hadi kwa Binadamu kwa Muda Mrefu Zaidi Uliofaulu"},"content":{"rendered":"
<\/div>\n

Madaktari wa upasuaji wa Marekani waliopandikiza figo ya nguruwe iliyobadilishwa vinasaba katika mgonjwa aliyekufa kwenye ubongo walitangaza Alhamisi kuwa wamemaliza majaribio yao baada ya kuvunja rekodi ya siku 61.<\/p>\n

Utaratibu wa hivi punde wa majaribio ni sehemu ya uwanja unaokua wa utafiti unaolenga kuendeleza upandikizaji wa spishi mbalimbali, hasa kujaribu mbinu kwenye miili ambayo imetolewa kwa ajili ya sayansi.<\/p>\n

Kuna zaidi ya watu 103,000 wanaosubiri upandikizaji wa viungo nchini Marekani, 88,000 kati yao wanahitaji figo.<\/p>\n

"Tumejifunza mengi katika miezi hii miwili iliyopita ya uchunguzi wa karibu na uchambuzi, na kuna sababu kubwa ya kuwa na matumaini kwa siku zijazo," Robert Montgomery, mkurugenzi wa Taasisi ya Upandikizaji ya Langone ya Chuo Kikuu cha New York, ambaye aliongoza upasuaji huo. Julai.<\/p>\n

Ilikuwa ni ya tano inayoitwa xenotransplant iliyofanywa na Montgomery, ambaye pia aliendesha upandikizaji wa kwanza wa figo wa nguruwe uliobadilishwa vinasaba mnamo Septemba 2021.<\/p>\n

Tishu zilizokusanywa wakati wa utafiti zilionyesha mchakato wa kukataa kidogo umeanza, unaohitaji kuimarishwa kwa dawa za kukandamiza kinga.<\/p>\n

Kwa "kung'oa" jeni inayohusika na biomolecule iitwayo alpha-gal - lengo kuu la kuzunguka kwa kingamwili za binadamu - timu ya NYU Langone iliweza kukomesha kukataliwa mara moja.<\/p>\n

Nguruwe wafadhili katika jaribio hili alitoka kwenye kundi linalolimwa na kampuni ya kibayoteki ya Virginia ya Revivicor.<\/p>\n

Kundi hilo pia limeidhinishwa na Utawala wa Chakula na Dawa kama chanzo cha nyama kwa watu walio na usikivu mkubwa kwa molekuli ya alpha-gal, mzio unaosababishwa na kuumwa na kupe.<\/p>\n

Nguruwe hawa hufugwa, sio kuumbwa, kumaanisha mchakato unaweza kupunguzwa kwa urahisi zaidi.<\/p>\n

Utafiti wa mapema wa xenotransplantation ulilenga kuvuna viungo kutoka kwa nyani - kwa mfano, moyo wa nyani ulipandikizwa ndani ya mtoto mchanga aliyejulikana kama "Baby Fae" mnamo 1984, lakini aliishi siku 20 pekee.<\/p>\n

Juhudi za sasa zinalenga nguruwe, ambao wanafikiriwa kuwa wafadhili bora kwa wanadamu kwa sababu ya ukubwa wa chombo, ukuaji wao wa haraka na takataka kubwa, na ukweli kwamba tayari wamefugwa kama chanzo cha chakula.<\/p>\n

Mnamo Januari 2022, madaktari wa upasuaji katika Chuo Kikuu cha Maryland Medical School walifanya upandikizaji wa kwanza duniani kutoka kwa nguruwe hadi kwa binadamu kwa mgonjwa aliye hai - wakati huu ukihusisha moyo.<\/p>\n

Alikufa miezi miwili baada ya hatua hiyo muhimu, na kuwepo kwa cytomegalovirus ya nguruwe katika chombo baadaye kulaumiwa.<\/p>\n

Wiki iliyopita, wanasayansi wa China walichapisha karatasi iliyoonyesha kuwa wamefaulu katika figo chotara za nguruwe-binadamu kwenye viinitete vya nguruwe, mbinu mbadala ambayo pia ina uwezo wa siku moja kusaidia kukabiliana na uhaba wa viungo vya mwili.<\/p>\n

Lakini maendeleo hayo yaliibua masuala ya kimaadili - hasa kwa vile baadhi ya seli za binadamu pia zilipatikana kwenye ubongo wa nguruwe, wataalam walisema.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Madaktari wa upasuaji wa Marekani waliopandikiza figo ya nguruwe iliyobadilishwa vinasaba katika mgonjwa aliyekufa kwenye ubongo walitangaza Alhamisi kuwa wamemaliza majaribio yao baada ya kuvunja rekodi ya siku 61.<\/p>\n

Utaratibu wa hivi punde wa majaribio ni sehemu ya uwanja unaokua wa utafiti unaolenga kuendeleza upandikizaji wa spishi mbalimbali, hasa kujaribu mbinu kwenye miili ambayo imetolewa kwa ajili ya sayansi.<\/p>\n

Kuna zaidi ya watu 103,000 wanaosubiri upandikizaji wa viungo nchini Marekani, 88,000 kati yao wanahitaji figo.<\/p>\n

"Tumejifunza mengi katika miezi hii miwili iliyopita ya uchunguzi wa karibu na uchambuzi, na kuna sababu kubwa ya kuwa na matumaini kwa siku zijazo," Robert Montgomery, mkurugenzi wa Taasisi ya Upandikizaji ya Langone ya Chuo Kikuu cha New York, ambaye aliongoza upasuaji huo. Julai.<\/p>\n

Ilikuwa ni ya tano inayoitwa xenotransplant iliyofanywa na Montgomery, ambaye pia aliendesha upandikizaji wa kwanza wa figo wa nguruwe uliobadilishwa vinasaba mnamo Septemba 2021.<\/p>\n

Tishu zilizokusanywa wakati wa utafiti zilionyesha mchakato wa kukataa kidogo umeanza, unaohitaji kuimarishwa kwa dawa za kukandamiza kinga.<\/p>\n

Kwa "kung'oa" jeni inayohusika na biomolecule iitwayo alpha-gal - lengo kuu la kuzunguka kwa kingamwili za binadamu - timu ya NYU Langone iliweza kukomesha kukataliwa mara moja.<\/p>\n

Nguruwe wafadhili katika jaribio hili alitoka kwenye kundi linalolimwa na kampuni ya kibayoteki ya Virginia ya Revivicor.<\/p>\n

Kundi hilo pia limeidhinishwa na Utawala wa Chakula na Dawa kama chanzo cha nyama kwa watu walio na usikivu mkubwa kwa molekuli ya alpha-gal, mzio unaosababishwa na kuumwa na kupe.<\/p>\n

Nguruwe hawa hufugwa, sio kuumbwa, kumaanisha mchakato unaweza kupunguzwa kwa urahisi zaidi.<\/p>\n

Utafiti wa mapema wa xenotransplantation ulilenga kuvuna viungo kutoka kwa nyani - kwa mfano, moyo wa nyani ulipandikizwa ndani ya mtoto mchanga aliyejulikana kama "Baby Fae" mnamo 1984, lakini aliishi siku 20 pekee.<\/p>\n

Juhudi za sasa zinalenga nguruwe, ambao wanafikiriwa kuwa wafadhili bora kwa wanadamu kwa sababu ya ukubwa wa chombo, ukuaji wao wa haraka na takataka kubwa, na ukweli kwamba tayari wamefugwa kama chanzo cha chakula.<\/p>\n

Mnamo Januari 2022, madaktari wa upasuaji katika Chuo Kikuu cha Maryland Medical School walifanya upandikizaji wa kwanza duniani kutoka kwa nguruwe hadi kwa binadamu kwa mgonjwa aliye hai - wakati huu ukihusisha moyo.<\/p>\n

Alikufa miezi miwili baada ya hatua hiyo muhimu, na kuwepo kwa cytomegalovirus ya nguruwe katika chombo baadaye kulaumiwa.<\/p>\n

Wiki iliyopita, wanasayansi wa China walichapisha karatasi iliyoonyesha kuwa wamefaulu katika figo chotara za nguruwe-binadamu kwenye viinitete vya nguruwe, mbinu mbadala ambayo pia ina uwezo wa siku moja kusaidia kukabiliana na uhaba wa viungo vya mwili.<\/p>\n

Lakini maendeleo hayo yaliibua masuala ya kimaadili - hasa kwa vile baadhi ya seli za binadamu pia zilipatikana kwenye ubongo wa nguruwe, wataalam walisema.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8644,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/us-surgeons-report-longest-successful-pig-to-human-kidney-transplant.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8643","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nUS Surgeons Report Longest Successful Pig-To-Human Kidney Transplant - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/madaktari-wetu-wa-upasuaji-wanaripoti-nguruwe-aliyefaulu-kwa-muda-mrefu-zaidi-kwa-upandikizaji-wa-figo-za-binadamu\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"US Surgeons Report Longest Successful Pig-To-Human Kidney Transplant - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"U.S. surgeons who transplanted a genetically modified pig kidney into a brain-dead patient announced Thursday they had ended their experiment after a record-breaking 61 days.The latest experimental procedure is part of a growing field of research aimed at advancing cross-species transplants, mainly testing the technique on bodies that have been donated for science.There are more than 103,000 people waiting for organ transplants in the United States, 88,000 of whom need kidneys."We have learned a great deal throughout these past two months of close observation and analysis, and there is great reason to be hopeful for the future," said Robert Montgomery, director of the New York University Langone Transplant Institute, who led the surgery in July.It was the fifth so-called xenotransplant performed by Montgomery, who also carried out the world's first genetically modified pig kidney transplant in September 2021.Tissue collected during the study indicated a mild rejection process had begun, requiring intensification of immunosuppression medication.By "knocking out" the gene responsible for a biomolecule called alpha-gal -- a prime target for roving human antibodies -- the NYU Langone team were able to stop immediate rejection.The donor pig in this experiment came from a herd cultivated by Virginia-based biotech company Revivicor.The herd has also been approved by the Food and Drug Administration as a source of meat for people with hypersensitivity to the alpha-gal molecule, an allergy caused by some tick bites.These pigs are bred, not cloned, meaning the process can be more easily scaled.Early xenotransplantation research focused on harvesting organs from primates -- for example, a baboon heart was transplanted into a newborn known as "Baby Fae" in 1984, but she survived only 20 days.Current efforts focus on pigs, which are thought to be ideal donors for humans because of their organ size, their rapid growth and large litters, and the fact they are already raised as a food source.In January 2022, surgeons at the University of Maryland Medical School carried out the world's first pig-to-human transplant on a living patient -- this time involving a heart.He died two months after the milestone, with the presence of porcine cytomegalovirus in the organ later blamed.Last week, Chinese scientists published a paper showing they had succeeded in hybrid pig-human kidneys in pig embryos, an alternative approach that also has the potential to one day help address organ donation shortages.But the development raised ethical issues -- especially since some human cells were also found in the pigs' brains, experts said.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" 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