{"id":8631,"date":"2023-09-08T10:17:04","date_gmt":"2023-09-08T07:17:04","guid":{"rendered":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/"},"modified":"2023-09-08T10:17:04","modified_gmt":"2023-09-08T07:17:04","slug":"saratani-ya-matiti-na-utafiti-wa-ujauzito-unaelezea-kwa-nini-akina-mama-wakubwa-kwa-mara-ya-kwanza-wako-kwenye-hatari-kubwa-zaidi","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/saratani-ya-matiti-na-utafiti-wa-ujauzito-unaelezea-kwa-nini-akina-mama-wakubwa-kwa-mara-ya-kwanza-wako-kwenye-hatari-kubwa-zaidi\/","title":{"rendered":"Saratani ya Matiti na Mimba: Utafiti Unaeleza Kwa Nini Akina Mama Wazee wa Mara ya Kwanza Wako Hatarini Zaidi"},"content":{"rendered":"
<\/div>\n

Kuna uhusiano mgumu kati ya saratani ya matiti na ujauzito. Katika utafiti, watafiti wanaeleza ni kwa nini wanawake wanaokuwa akina mama mara ya kwanza baadaye maishani wana hatari kubwa ya kupata saratani ya matiti kwa muda mrefu kuliko wale ambao wanakuwa mama mapema.<\/p>\n

Uchunguzi unaonyesha kuwa akina mama wachanga wanaozaliwa kwa mara ya kwanza, wale walio chini ya umri wa miaka 24 wakati wa ujauzito wao wa awali, wanapata hatari ndogo sana ya muda mrefu ya kupata mtoto. saratani ya matiti<\/a> (takriban 20-35%) ikilinganishwa na wanawake ambao hawajapata watoto.<\/p>\n

Hata hivyo, umri wa akina mama wanaozaliwa mara ya kwanza unapoongezeka, hatari ya saratani ya matiti pia huongezeka hatua kwa hatua, na ongezeko la 5% katika hatari kila baada ya miaka mitano.<\/p>\n

"Katika miongo ya hivi karibuni, wanawake wameanza kupata watoto baadaye kwa sababu ya mabadiliko ya kijamii na mapendeleo ya kibinafsi. Utafiti wa awali umegundua kuwa hii inahusishwa na hatari kubwa ya saratani ya matiti," Dk Biancastella Cereser, mwandishi mkuu wa utafiti huo, alisema katika taarifa ya habari.<\/p>\n

"Utafiti wetu wenyewe unaangazia mafumbo ya kijeni ambayo yanatawala hatari hii. Tuligundua kuwa matiti ya binadamu, kama viungo vingine, hujilimbikiza mabadiliko kulingana na umri, lakini pia kwamba ujauzito una athari ya ziada, ikimaanisha kuwa akina mama wakubwa wanaougua mara ya kwanza wanaweza kuwa na nafasi kubwa ya kupata mabadiliko hatari katika seli zao za matiti ikilinganishwa na wanawake wengine. \u201d Cereser alisema.<\/p>\n

Katika utafiti wa hivi karibuni, uliochapishwa katika jarida<\/a> Nature Communications, watafiti walichambua mabadiliko ya seli na ya kijeni ambayo hutokea kwa seli za matiti zenye afya zinapogeuka ya saratani<\/a>. Baada ya kupanga tishu 29 za matiti zenye afya zilizogandishwa kutoka kwa wafadhili, timu iligundua kuwa kadiri umri unavyosonga, tishu hizi za matiti zenye afya hukusanya mabadiliko, kwa kiwango cha karibu mabadiliko 15 kila mwaka. Ingawa mabadiliko mengi haya hayaathiri jeni na hayasababishi saratani, kadiri muda unavyopita, kuna uwezekano mkubwa wa kuwa na mabadiliko yanayohusiana na saratani.<\/p>\n

"Hii inaweza kuwa haitoshi kusababisha saratani yenyewe. Lakini, ujauzito unaweza kutoa 'mshangao maradufu', kwa sababu huchochea upanuzi wa haraka wa seli za matiti, katika maandalizi ya kunyonyesha. Ikiwa seli zilizo na mabadiliko ya kiendeshaji zinajirudia na kupanuka, zinaweza kuwa na faida ya ushindani dhidi ya seli jirani ambazo hazijabadilishwa, na hivyo kusababisha athari ya kukimbia, na hatimaye kuunda uvimbe wa saratani," Cereser alielezea.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Kuna uhusiano mgumu kati ya saratani ya matiti na ujauzito. Katika utafiti, watafiti wanaeleza ni kwa nini wanawake wanaokuwa akina mama mara ya kwanza baadaye maishani wana hatari kubwa ya kupata saratani ya matiti kwa muda mrefu kuliko wale ambao wanakuwa mama mapema.<\/p>\n

Uchunguzi unaonyesha kuwa akina mama wachanga wanaozaliwa kwa mara ya kwanza, wale walio chini ya umri wa miaka 24 wakati wa ujauzito wao wa awali, wanapata hatari ndogo sana ya muda mrefu ya kupata mtoto. saratani ya matiti<\/a> (takriban 20-35%) ikilinganishwa na wanawake ambao hawajapata watoto.<\/p>\n

Hata hivyo, umri wa akina mama wanaozaliwa mara ya kwanza unapoongezeka, hatari ya saratani ya matiti pia huongezeka hatua kwa hatua, na ongezeko la 5% katika hatari kila baada ya miaka mitano.<\/p>\n

"Katika miongo ya hivi karibuni, wanawake wameanza kupata watoto baadaye kwa sababu ya mabadiliko ya kijamii na mapendeleo ya kibinafsi. Utafiti wa awali umegundua kuwa hii inahusishwa na hatari kubwa ya saratani ya matiti," Dk Biancastella Cereser, mwandishi mkuu wa utafiti huo, alisema katika taarifa ya habari.<\/p>\n

"Utafiti wetu wenyewe unaangazia mafumbo ya kijeni ambayo yanatawala hatari hii. Tuligundua kuwa matiti ya binadamu, kama viungo vingine, hujilimbikiza mabadiliko kulingana na umri, lakini pia kwamba ujauzito una athari ya ziada, ikimaanisha kuwa akina mama wakubwa wanaougua mara ya kwanza wanaweza kuwa na nafasi kubwa ya kupata mabadiliko hatari katika seli zao za matiti ikilinganishwa na wanawake wengine. \u201d Cereser alisema.<\/p>\n

Katika utafiti wa hivi karibuni, uliochapishwa katika jarida<\/a> Nature Communications, watafiti walichambua mabadiliko ya seli na ya kijeni ambayo hutokea kwa seli za matiti zenye afya zinapogeuka ya saratani<\/a>. Baada ya kupanga tishu 29 za matiti zenye afya zilizogandishwa kutoka kwa wafadhili, timu iligundua kuwa kadiri umri unavyosonga, tishu hizi za matiti zenye afya hukusanya mabadiliko, kwa kiwango cha karibu mabadiliko 15 kila mwaka. Ingawa mabadiliko mengi haya hayaathiri jeni na hayasababishi saratani, kadiri muda unavyopita, kuna uwezekano mkubwa wa kuwa na mabadiliko yanayohusiana na saratani.<\/p>\n

"Hii inaweza kuwa haitoshi kusababisha saratani yenyewe. Lakini, ujauzito unaweza kutoa 'mshangao maradufu', kwa sababu huchochea upanuzi wa haraka wa seli za matiti, katika maandalizi ya kunyonyesha. Ikiwa seli zilizo na mabadiliko ya kiendeshaji zinajirudia na kupanuka, zinaweza kuwa na faida ya ushindani dhidi ya seli jirani ambazo hazijabadilishwa, na hivyo kusababisha athari ya kukimbia, na hatimaye kuunda uvimbe wa saratani," Cereser alielezea.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8632,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8631","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nBreast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/saratani-ya-matiti-na-utafiti-wa-ujauzito-unaelezea-kwa-nini-akina-mama-wakubwa-kwa-mara-ya-kwanza-wako-kwenye-hatari-kubwa-zaidi\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Breast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"There is an intricate connection between breast cancer and pregnancy. In a study, researchers explain why women who become first-time mothers later in life have a higher long-term risk of breast cancer than those who become moms early.Studies show that young first-time mothers, those who are below the age of 24 during their initial pregnancy, experience a substantially lower long-term risk of breast cancer (approximately 20-35%) compared to women who have not had kids.However, as the age of first-time mothers goes up, the breast cancer risk also progressively increases, with a 5% spike in risk every five years."In recent decades, women have begun having children later because of societal changes and personal preferences. Previous research has found that this is associated with a heightened breast cancer risk," Dr. Biancastella Cereser, a lead author of the study, said in the news release."Our own research delves into the genetic mysteries that govern this risk. We found that the human breast, like other organs, accumulates mutations with age, but also that pregnancy has an additional effect, meaning that older first-time mothers might have a higher chance of developing harmful changes in their breast cells compared to other women," Cereser said.In the latest study, published in the journal Nature Communications, researchers analyzed the cellular and genetic changes that happen to healthy breast cells as they turn cancerous. After sequencing 29 frozen healthy breast tissues from donors, the team found that with age, these healthy breast tissues accumulate mutations, at the rate of around 15 mutations every year. Although the majority of these mutations do not affect the genes and are not cancer-causing, with more time, there is a greater chance of having driver mutations associated with cancer."This might not be enough to cause cancer by itself. But, pregnancy could provide a 'double whammy', because it induces a rapid expansion of breast cells, in preparation for breastfeeding. 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