{"id":8303,"date":"2023-06-06T09:32:34","date_gmt":"2023-06-06T06:32:34","guid":{"rendered":"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/"},"modified":"2023-06-06T09:32:34","modified_gmt":"2023-06-06T06:32:34","slug":"utafiti-wa-tiba-ya-uingizwaji-wa-homoni-unasema-kuchukua-estrojeni-kwa-mdomo-huongeza-hatari-ya-shinikizo-la-damu","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/utafiti-wa-tiba-ya-uingizwaji-wa-homoni-unasema-kuchukua-estrojeni-kwa-mdomo-huongeza-hatari-ya-shinikizo-la-damu\/","title":{"rendered":"Tiba ya Kubadilisha Homoni: Utafiti Unasema Kuchukua Estrojeni ya Kinywa Huongeza Hatari ya Shinikizo la damu"},"content":{"rendered":"<p>Wanawake wanaotumia tembe za estrojeni kama sehemu ya tiba yao ya homoni za kukoma hedhi wako katika hatari kubwa ya kupata shinikizo la damu, utafiti wa hivi karibuni umegundua.<\/p>\n<p>Wakati mwanamke anapokoma hedhi, ovari zake hazitoi tena viwango vya juu vya estrojeni na progesterone kama hapo awali. Kushuka huku kwa ghafla kwa homoni husababisha usumbufu kadhaa kama vile kuwaka moto, kutokwa na jasho usiku, mabadiliko ya hisia na ugumu wa kulala.<\/p>\n<p>Tiba ya uingizwaji wa homoni mara nyingi hupendekezwa kwa wanawake waliokoma hedhi ili kupunguza dalili, na kupunguza hatari ya osteoporosis na magonjwa ya moyo na mishipa yanayohusiana na kushuka kwa homoni.<\/p>\n<p>Kuna aina mbili kuu za h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">matibabu ya uingizwaji wa ormone<\/a> - tiba ya estrojeni na tiba ya progesterone\/projestini ya homoni (EPT).<\/p>\n<p>Tiba ya estrojeni inahusisha matumizi ya estrojeni kwa namna ya kidonge, kiraka, cream, pete ya uke, gel, au dawa. EPT, pia inajulikana kama tiba mchanganyiko, inachanganya vipimo vya estrojeni na progesterone.<\/p>\n<p>Aina ya matibabu ya homoni huamua kulingana na mambo kadhaa, ikiwa ni pamoja na ikiwa mgonjwa amepata hysterectomy. Mchanganyiko wa estrojeni na progesterone hutumiwa kwa wanawake walio na uterasi ili kupunguza hatari ya saratani ya endometriamu. Hata hivyo, matibabu ya estrojeni pekee yanaaminika kuwa na hatari chache za muda mrefu ikilinganishwa na tiba mchanganyiko.<\/p>\n<p>Katika karibuni <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">kusoma<\/a>, iliyochapishwa katika jarida la Chama cha Moyo cha Marekani Shinikizo la damu, watafiti walichunguza data kutoka kwa zaidi ya wanawake 112,000 waliokuwa na umri wa miaka 45 au zaidi baada ya kuwekwa kwenye tiba ya homoni ya estrojeni pekee kwa mwaka mmoja.<\/p>\n<p>Watafiti walichunguza uhusiano kati ya njia ya utawala wa estrojeni - matumizi ya mdomo, transdermal na uke - na hatari ya kuendeleza shinikizo la damu.<\/p>\n<p>Kwa mujibu wa <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">watafiti<\/a>, kuchukua estrojeni ya mdomo iliongeza hatari ya shinikizo la damu kwa 14% ikilinganishwa na matibabu ya homoni kwa kutumia krimu za estrojeni zinazopita ngozi. Hatari ya tembe za estrojeni ilikuwa 19% ikilinganishwa na matumizi ya krimu za estrojeni za uke au suppositories.<\/p>\n<p>&quot;Tunajua estrogens kumeza kwa mdomo ni metabolized kupitia ini, na hii inahusishwa na ongezeko la mambo ambayo yanaweza kusababisha shinikizo la damu,&quot; alisema Cindy Kalenga, mwandishi mkuu wa utafiti huo.<\/p>\n<p>Timu ya utafiti pia iligundua kuwa kuchukua estrojeni kwa muda mrefu au matumizi ya dozi ya juu kulihusishwa na hatari kubwa ya shinikizo la damu.<\/p>\n<p>\u201cTunajua hilo <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">baada ya menopausal<\/a> wanawake wana hatari ya kuongezeka kwa shinikizo la damu ikilinganishwa na wanawake kabla ya hedhi, zaidi ya hayo, tafiti za awali zimeonyesha kuwa aina maalum za tiba ya homoni zimehusishwa na viwango vya juu vya ugonjwa wa moyo. Tulichagua kuzama zaidi katika mambo yanayohusiana na tiba ya homoni, kama vile njia ya utawala (ya mdomo dhidi ya isiyo ya mdomo) na aina ya estrojeni, na jinsi yanavyoweza kuathiri shinikizo la damu,&quot; Kalenga alisema.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><picture class=\"mapping-embed\" width=\"736\" height=\"1103\"><source type=\"image\/webp\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/jpeg\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/webp\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/jpeg\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/webp\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"mtu mzima\" width=\"736\" height=\"1103\" style=\"display:none\"><\/picture><\/div><figcaption class=\"caption\">\n<span class=\"cap\">Kukoma hedhi kunaweza kusababisha kila kitu kuanzia kuwaka moto hadi kupoteza kumbukumbu. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Imechapishwa na Medicaldaily.com<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-hypertension-470012\">Chanzo cha matibabu cha kila siku<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Wanawake wanaotumia tembe za estrojeni kama sehemu ya tiba yao ya homoni za kukoma hedhi wako katika hatari kubwa ya kupata shinikizo la damu, utafiti wa hivi karibuni umegundua.<\/p>\n<p>Wakati mwanamke anapokoma hedhi, ovari zake hazitoi tena viwango vya juu vya estrojeni na progesterone kama hapo awali. Kushuka huku kwa ghafla kwa homoni husababisha usumbufu kadhaa kama vile kuwaka moto, kutokwa na jasho usiku, mabadiliko ya hisia na ugumu wa kulala.<\/p>\n<p>Tiba ya uingizwaji wa homoni mara nyingi hupendekezwa kwa wanawake waliokoma hedhi ili kupunguza dalili, na kupunguza hatari ya osteoporosis na magonjwa ya moyo na mishipa yanayohusiana na kushuka kwa homoni.<\/p>\n<p>Kuna aina mbili kuu za h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">matibabu ya uingizwaji wa ormone<\/a> - tiba ya estrojeni na tiba ya progesterone\/projestini ya homoni (EPT).<\/p>\n<p>Tiba ya estrojeni inahusisha matumizi ya estrojeni kwa namna ya kidonge, kiraka, cream, pete ya uke, gel, au dawa. EPT, pia inajulikana kama tiba mchanganyiko, inachanganya vipimo vya estrojeni na progesterone.<\/p>\n<p>Aina ya matibabu ya homoni huamua kulingana na mambo kadhaa, ikiwa ni pamoja na ikiwa mgonjwa amepata hysterectomy. Mchanganyiko wa estrojeni na progesterone hutumiwa kwa wanawake walio na uterasi ili kupunguza hatari ya saratani ya endometriamu. Hata hivyo, matibabu ya estrojeni pekee yanaaminika kuwa na hatari chache za muda mrefu ikilinganishwa na tiba mchanganyiko.<\/p>\n<p>Katika karibuni <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">kusoma<\/a>, iliyochapishwa katika jarida la Chama cha Moyo cha Marekani Shinikizo la damu, watafiti walichunguza data kutoka kwa zaidi ya wanawake 112,000 waliokuwa na umri wa miaka 45 au zaidi baada ya kuwekwa kwenye tiba ya homoni ya estrojeni pekee kwa mwaka mmoja.<\/p>\n<p>Watafiti walichunguza uhusiano kati ya njia ya utawala wa estrojeni - matumizi ya mdomo, transdermal na uke - na hatari ya kuendeleza shinikizo la damu.<\/p>\n<p>Kwa mujibu wa <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">watafiti<\/a>, kuchukua estrojeni ya mdomo iliongeza hatari ya shinikizo la damu kwa 14% ikilinganishwa na matibabu ya homoni kwa kutumia krimu za estrojeni zinazopita ngozi. Hatari ya tembe za estrojeni ilikuwa 19% ikilinganishwa na matumizi ya krimu za estrojeni za uke au suppositories.<\/p>\n<p>&quot;Tunajua estrogens kumeza kwa mdomo ni metabolized kupitia ini, na hii inahusishwa na ongezeko la mambo ambayo yanaweza kusababisha shinikizo la damu,&quot; alisema Cindy Kalenga, mwandishi mkuu wa utafiti huo.<\/p>\n<p>Timu ya utafiti pia iligundua kuwa kuchukua estrojeni kwa muda mrefu au matumizi ya dozi ya juu kulihusishwa na hatari kubwa ya shinikizo la damu.<\/p>\n<p>\u201cTunajua hilo <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">baada ya menopausal<\/a> wanawake wana hatari ya kuongezeka kwa shinikizo la damu ikilinganishwa na wanawake kabla ya hedhi, zaidi ya hayo, tafiti za awali zimeonyesha kuwa aina maalum za tiba ya homoni zimehusishwa na viwango vya juu vya ugonjwa wa moyo. Tulichagua kuzama zaidi katika mambo yanayohusiana na tiba ya homoni, kama vile njia ya utawala (ya mdomo dhidi ya isiyo ya mdomo) na aina ya estrojeni, na jinsi yanavyoweza kuathiri shinikizo la damu,&quot; Kalenga alisema.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"mtu mzima\" width=\"736\" height=\"1103\"><\/div><figcaption class=\"caption\">\n<span class=\"cap\">Kukoma hedhi kunaweza kusababisha kila kitu kuanzia kuwaka moto hadi kupoteza kumbukumbu. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Imechapishwa na Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8304,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8303","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/utafiti-wa-tiba-ya-uingizwaji-wa-homoni-unasema-kuchukua-estrojeni-kwa-mdomo-huongeza-hatari-ya-shinikizo-la-damu\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.&quot;We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,&quot; said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.&quot;We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,&quot; Kalenga said. Menopause can cause everything from hot flashes to memory loss. Pixabay Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/sw\/utafiti-wa-tiba-ya-uingizwaji-wa-homoni-unasema-kuchukua-estrojeni-kwa-mdomo-huongeza-hatari-ya-shinikizo-la-damu\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-06T06:32:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"dakika 2\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension\",\"datePublished\":\"2023-06-06T06:32:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"wordCount\":455,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"sw\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"url\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"name\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - 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Kliniki ya Huduma ya Mjini","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/sw\/utafiti-wa-tiba-ya-uingizwaji-wa-homoni-unasema-kuchukua-estrojeni-kwa-mdomo-huongeza-hatari-ya-shinikizo-la-damu\/","og_locale":"en_US","og_type":"article","og_title":"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic","og_description":"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.\"We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,\" said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.\"We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,\" Kalenga said. Menopause can cause everything from hot flashes to memory loss. 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