{"id":8202,"date":"2023-05-19T03:24:07","date_gmt":"2023-05-19T00:24:07","guid":{"rendered":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"modified":"2023-05-23T17:29:53","modified_gmt":"2023-05-23T14:29:53","slug":"ambaye-anataka-watengenezaji-wa-chanjo-waache-aina-asilia-katika-viunda-vilivyosasishwa","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","title":{"rendered":"WHO Inawataka Watengenezaji Chanjo Kuacha Aina Ya Asili Katika Michanganyiko Iliyosasishwa"},"content":{"rendered":"
<\/div>\n

Shirika la Afya Duniani (WHO) limetoa taarifa kuhusu muundo wa antijeni wa chanjo ya COVID-19.<\/p>\n

Shirika hilo maalumu la Umoja wa Mataifa lilisema Alhamisi kwamba watengenezaji chanjo wanapaswa kubuni visasisho ambavyo havilengi tena aina ya awali ya SARS-CoV-2.<\/p>\n

"Ingawa chanjo za COVID-19 zilizoidhinishwa kwa sasa, pamoja na zile zinazozingatia virusi vya index, zinaendelea kutoa kinga dhidi ya ugonjwa mbaya, TAG-CO-VAC inashauri kuondokana na kujumuishwa kwa virusi vya index katika uundaji wa baadaye wa chanjo ya COVID-19, \u201d ya WHO ilisema kwenye tovuti yake<\/a>.<\/p>\n

TAG-CO-VAC ni Kikundi cha Ushauri cha Kiufundi cha WHO kuhusu Muundo wa Chanjo ya COVID-19. Kikundi cha ushauri kina jukumu la kukusanyika mara kwa mara ili kutathmini athari za mabadiliko mapya zaidi kwa muundo wa antijeni wa chanjo za siku zijazo.<\/p>\n

Kwa mwaka huu, TAG-CO-VAC inatarajiwa kukutana angalau mara mbili. Ya kwanza ilipangwa Mei, na ufuatiliaji unapaswa kufanywa karibu miezi sita baadaye. Kikundi kilikutana rasmi mnamo Mei 11-12 ili kujadili data ya hivi punde juu ya kusambaza lahaja za SARS-CoV-2 na muundo wa chanjo.<\/p>\n

Mwaka jana, TAG-CO-VAC imesema<\/a> kwamba lengo la kusasisha muundo wa antijeni ya chanjo ya COVID-19 lilikuwa kuboresha mwitikio wa kinga unaotokana na chanjo kwa anuwai zinazozunguka za coronavirus kwa sasa. Ikiwa kikundi kitapata hitaji la kubadilisha viundaji, kitashauri WHO kuwajulisha watengenezaji wote wa chanjo.<\/p>\n

Mapendekezo ya hivi punde ya kikundi kuacha aina ya awali katika uundaji wa siku zijazo ni kutokana na sababu kadhaa. Mojawapo inahusiana na virusi vya index na aina zingine za mapema ambazo hazizunguki tena kwa wanadamu. Sababu nyingine ni jinsi aina asili inavyoleta viwango visivyoweza kutambulika au vya chini sana vya kupunguza kingamwili dhidi ya vibadala vipya zaidi.<\/p>\n

Sababu ya tatu iliyotajwa na kikundi ina uhusiano fulani na mkusanyiko wa utunzi. Kwa kujumuisha virusi vya fahirisi katika chanjo na viboreshaji vya aina mbili au nyingi, mkusanyiko wa antijeni lengwa mpya unaweza kuwa mdogo. Hii inapunguza ukubwa wa mwitikio wa kinga ya humoral dhidi ya vibadala vinavyozunguka kwa sasa.<\/p>\n

TAG-CO-VAC ilikubali mapungufu ya data inayopatikana kuhusu muda, mabadiliko mahususi, sifa za antijeni na hatari zinazoweza kutokea kwa afya ya umma za vibadala vya siku zijazo. Taarifa kuhusu utendakazi mtambuka wa majibu ya kinga yanayotokana na aina mpya pia ni mdogo. Wakati huo huo, data juu ya chanjo za watahiniwa dhidi ya ukoo wa ukoo wa XBB.1 bado ni wa mifano ya wanyama.<\/p>\n

Licha ya mapungufu, kikundi cha washauri kilisema kinaendelea kuhimiza maendeleo ya baadaye ya chanjo ya COVID-19 ambayo huongeza kinga ya mucosal kwa ulinzi bora dhidi ya maambukizo ya virusi na kupunguza maambukizi ya SARS-CoV-2, haswa katika enzi ya baada ya janga<\/a>.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Shirika la Afya Duniani (WHO) limetoa taarifa kuhusu muundo wa antijeni wa chanjo ya COVID-19.<\/p>\n

Shirika hilo maalumu la Umoja wa Mataifa lilisema Alhamisi kwamba watengenezaji chanjo wanapaswa kubuni visasisho ambavyo havilengi tena aina ya awali ya SARS-CoV-2.<\/p>\n

"Ingawa chanjo za COVID-19 zilizoidhinishwa kwa sasa, pamoja na zile zinazozingatia virusi vya index, zinaendelea kutoa kinga dhidi ya ugonjwa mbaya, TAG-CO-VAC inashauri kuondokana na kujumuishwa kwa virusi vya index katika uundaji wa baadaye wa chanjo ya COVID-19, \u201d ya WHO ilisema kwenye tovuti yake<\/a>.<\/p>\n

TAG-CO-VAC ni Kikundi cha Ushauri cha Kiufundi cha WHO kuhusu Muundo wa Chanjo ya COVID-19. Kikundi cha ushauri kina jukumu la kukusanyika mara kwa mara ili kutathmini athari za mabadiliko mapya zaidi kwa muundo wa antijeni wa chanjo za siku zijazo.<\/p>\n

Kwa mwaka huu, TAG-CO-VAC inatarajiwa kukutana angalau mara mbili. Ya kwanza ilipangwa Mei, na ufuatiliaji unapaswa kufanywa karibu miezi sita baadaye. Kikundi kilikutana rasmi mnamo Mei 11-12 ili kujadili data ya hivi punde juu ya kusambaza lahaja za SARS-CoV-2 na muundo wa chanjo.<\/p>\n

Mwaka jana, TAG-CO-VAC imesema<\/a> kwamba lengo la kusasisha muundo wa antijeni ya chanjo ya COVID-19 lilikuwa kuboresha mwitikio wa kinga unaotokana na chanjo kwa anuwai zinazozunguka za coronavirus kwa sasa. Ikiwa kikundi kitapata hitaji la kubadilisha viundaji, kitashauri WHO kuwajulisha watengenezaji wote wa chanjo.<\/p>\n

Mapendekezo ya hivi punde ya kikundi kuacha aina ya awali katika uundaji wa siku zijazo ni kutokana na sababu kadhaa. Mojawapo inahusiana na virusi vya index na aina zingine za mapema ambazo hazizunguki tena kwa wanadamu. Sababu nyingine ni jinsi aina asili inavyoleta viwango visivyoweza kutambulika au vya chini sana vya kupunguza kingamwili dhidi ya vibadala vipya zaidi.<\/p>\n

Sababu ya tatu iliyotajwa na kikundi ina uhusiano fulani na mkusanyiko wa utunzi. Kwa kujumuisha virusi vya fahirisi katika chanjo na viboreshaji vya aina mbili au nyingi, mkusanyiko wa antijeni lengwa mpya unaweza kuwa mdogo. Hii inapunguza ukubwa wa mwitikio wa kinga ya humoral dhidi ya vibadala vinavyozunguka kwa sasa.<\/p>\n

TAG-CO-VAC ilikubali mapungufu ya data inayopatikana kuhusu muda, mabadiliko mahususi, sifa za antijeni na hatari zinazoweza kutokea kwa afya ya umma za vibadala vya siku zijazo. Taarifa kuhusu utendakazi mtambuka wa majibu ya kinga yanayotokana na aina mpya pia ni mdogo. Wakati huo huo, data juu ya chanjo za watahiniwa dhidi ya ukoo wa ukoo wa XBB.1 bado ni wa mifano ya wanyama.<\/p>\n

Licha ya mapungufu, kikundi cha washauri kilisema kinaendelea kuhimiza maendeleo ya baadaye ya chanjo ya COVID-19 ambayo huongeza kinga ya mucosal kwa ulinzi bora dhidi ya maambukizo ya virusi na kupunguza maambukizi ya SARS-CoV-2, haswa katika enzi ya baada ya janga<\/a>.<\/p>\n

Imechapishwa na Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8203,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[193],"class_list":["post-8202","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-vaccination"],"yoast_head":"\nWHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/ambaye-anataka-watengenezaji-wa-chanjo-waache-aina-asilia-katika-viunda-vilivyosasishwa\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"The World Health Organization (WHO) has issued a statement on the antigen composition of the COVID-19 vaccines.The specialized agency of the United Nations said Thursday that vaccine manufacturers should design updates that no longer target the original strain of SARS-CoV-2."While currently approved COVID-19 vaccines, including those based on the index virus, continue to provide protection against severe disease, the TAG-CO-VAC advises moving away from the inclusion of the index virus in future formulations of COVID-19 vaccines," the WHO stated on its website.TAG-CO-VAC is the WHO's Technical Advisory Group on COVID-19 Vaccine Composition. The advisory group is tasked to convene regularly to assess the implications of newer mutations for the antigen composition of future vaccines.For this year, TAG-CO-VAC is expected to meet at least twice. The first one was scheduled in May, and a follow-up should be done about six months later. The group officially convened on May 11-12 to discuss the latest data on circulating SARS-CoV-2 variants and vaccine composition.Last year, TAG-CO-VAC stated that the objective of updating the COVID-19 vaccine antigen composition was to enhance vaccine-induced immune responses to currently circulating coronavirus variants. Should the group find the need to change formulations, it would advise the WHO to inform all vaccine manufacturers.The latest recommendation of the group to ditch the original strain in future formulations is due to several reasons. One of which has to do with the index virus and other earlier strains no longer circulating in humans. Another reason is how the original strain elicits undetectable or very low levels of neutralizing antibodies against the newer variants.The third reason cited by the group has something to do with the concentration of the composition. By including the index virus in the bivalent or multivalent vaccines and boosters, the concentration of the new target antigens may be lower. This decreases the magnitude of the humoral immune response against the currently circulating variants.TAG-CO-VAC acknowledged the limitations of the available data on the timing, specific mutations, antigenic characteristics and potential public health risks of future variants. Information on the cross-reactivity of immune responses elicited by newer strains is also limited. Meanwhile, data on candidate vaccines against XBB.1 descendent lineage are still limited to animal models.Despite the limitations, the advisory group said it continues to encourage the future development of COVID-19 vaccines that enhance mucosal immunity for improved protection against viral infection and reduce the transmission of SARS-CoV-2, especially in the post-pandemic era.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/sw\/ambaye-anataka-watengenezaji-wa-chanjo-waache-aina-asilia-katika-viunda-vilivyosasishwa\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-19T00:24:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-23T14:29:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"dakika 2\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\",\"datePublished\":\"2023-05-19T00:24:07+00:00\",\"dateModified\":\"2023-05-23T14:29:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"},\"wordCount\":429,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"keywords\":[\"Vaccination\"],\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"sw\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\",\"name\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"datePublished\":\"2023-05-19T00:24:07+00:00\",\"dateModified\":\"2023-05-23T14:29:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#breadcrumb\"},\"inLanguage\":\"sw\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"sw\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"contentUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"caption\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/urbancare.clinic\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#website\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/\",\"name\":\"Urban Care Clinic\",\"description\":\"Your Medical Healthcare Clinic in Zanzibar\",\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/urbancare.clinic\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"sw\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\",\"name\":\"Urban Care Clinic Zanzibar\",\"alternateName\":\"Urban Care Clinic\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sw\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/Urban-Care-Clinic-Logo-Trans-512x512-1.png\",\"contentUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/Urban-Care-Clinic-Logo-Trans-512x512-1.png\",\"width\":500,\"height\":500,\"caption\":\"Urban Care Clinic Zanzibar\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/urbancarezanzibar\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\",\"name\":\"Urban Care Clinic\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sw\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"caption\":\"Urban Care Clinic\"},\"url\":\"https:\\\/\\\/urbancare.clinic\\\/sw\\\/author\\\/urban-care-clinic\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"WHO Yawataka Watengenezaji Chanjo Kuacha Aina Halisi Katika Michanganyiko Iliyosasishwa - Kliniki ya Utunzaji Mijini","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/sw\/ambaye-anataka-watengenezaji-wa-chanjo-waache-aina-asilia-katika-viunda-vilivyosasishwa\/","og_locale":"en_US","og_type":"article","og_title":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic","og_description":"The World Health Organization (WHO) has issued a statement on the antigen composition of the COVID-19 vaccines.The specialized agency of the United Nations said Thursday that vaccine manufacturers should design updates that no longer target the original strain of SARS-CoV-2.\"While currently approved COVID-19 vaccines, including those based on the index virus, continue to provide protection against severe disease, the TAG-CO-VAC advises moving away from the inclusion of the index virus in future formulations of COVID-19 vaccines,\" the WHO stated on its website.TAG-CO-VAC is the WHO's Technical Advisory Group on COVID-19 Vaccine Composition. The advisory group is tasked to convene regularly to assess the implications of newer mutations for the antigen composition of future vaccines.For this year, TAG-CO-VAC is expected to meet at least twice. The first one was scheduled in May, and a follow-up should be done about six months later. The group officially convened on May 11-12 to discuss the latest data on circulating SARS-CoV-2 variants and vaccine composition.Last year, TAG-CO-VAC stated that the objective of updating the COVID-19 vaccine antigen composition was to enhance vaccine-induced immune responses to currently circulating coronavirus variants. Should the group find the need to change formulations, it would advise the WHO to inform all vaccine manufacturers.The latest recommendation of the group to ditch the original strain in future formulations is due to several reasons. One of which has to do with the index virus and other earlier strains no longer circulating in humans. Another reason is how the original strain elicits undetectable or very low levels of neutralizing antibodies against the newer variants.The third reason cited by the group has something to do with the concentration of the composition. By including the index virus in the bivalent or multivalent vaccines and boosters, the concentration of the new target antigens may be lower. This decreases the magnitude of the humoral immune response against the currently circulating variants.TAG-CO-VAC acknowledged the limitations of the available data on the timing, specific mutations, antigenic characteristics and potential public health risks of future variants. Information on the cross-reactivity of immune responses elicited by newer strains is also limited. Meanwhile, data on candidate vaccines against XBB.1 descendent lineage are still limited to animal models.Despite the limitations, the advisory group said it continues to encourage the future development of COVID-19 vaccines that enhance mucosal immunity for improved protection against viral infection and reduce the transmission of SARS-CoV-2, especially in the post-pandemic era.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/sw\/ambaye-anataka-watengenezaji-wa-chanjo-waache-aina-asilia-katika-viunda-vilivyosasishwa\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-05-19T00:24:07+00:00","article_modified_time":"2023-05-23T14:29:53+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Urban Care Clinic","Est. reading time":"dakika 2"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations","datePublished":"2023-05-19T00:24:07+00:00","dateModified":"2023-05-23T14:29:53+00:00","mainEntityOfPage":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"wordCount":429,"publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"image":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","keywords":["Vaccination"],"articleSection":["Medical Daily"],"inLanguage":"sw"},{"@type":"WebPage","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","url":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","name":"WHO Yawataka Watengenezaji Chanjo Kuacha Aina Halisi Katika Michanganyiko Iliyosasishwa - Kliniki ya Utunzaji Mijini","isPartOf":{"@id":"https:\/\/urbancare.clinic\/#website"},"primaryImageOfPage":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"image":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","datePublished":"2023-05-19T00:24:07+00:00","dateModified":"2023-05-23T14:29:53+00:00","breadcrumb":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#breadcrumb"},"inLanguage":"sw","potentialAction":[{"@type":"ReadAction","target":["https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"]}]},{"@type":"ImageObject","inLanguage":"sw","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage","url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","contentUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","caption":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations"},{"@type":"BreadcrumbList","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/urbancare.clinic\/"},{"@type":"ListItem","position":2,"name":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations"}]},{"@type":"WebSite","@id":"https:\/\/urbancare.clinic\/#website","url":"https:\/\/urbancare.clinic\/","name":"Kliniki ya Huduma ya Mjini","description":"Kliniki yako ya Afya Zanzibar","publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/urbancare.clinic\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"sw"},{"@type":"Organization","@id":"https:\/\/urbancare.clinic\/#organization","name":"Kliniki ya Huduma ya Mijini Zanzibar","alternateName":"Urban Care Clinic","url":"https:\/\/urbancare.clinic\/","logo":{"@type":"ImageObject","inLanguage":"sw","@id":"https:\/\/urbancare.clinic\/#\/schema\/logo\/image\/","url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/07\/Urban-Care-Clinic-Logo-Trans-512x512-1.png","contentUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/07\/Urban-Care-Clinic-Logo-Trans-512x512-1.png","width":500,"height":500,"caption":"Urban Care Clinic Zanzibar"},"image":{"@id":"https:\/\/urbancare.clinic\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/urbancarezanzibar"]},{"@type":"Person","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930","name":"Kliniki ya Huduma ya Mjini","image":{"@type":"ImageObject","inLanguage":"sw","@id":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","caption":"Urban Care Clinic"},"url":"https:\/\/urbancare.clinic\/sw\/author\/urban-care-clinic\/"}]}},"_links":{"self":[{"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/posts\/8202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/comments?post=8202"}],"version-history":[{"count":0,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/posts\/8202\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/media\/8203"}],"wp:attachment":[{"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/media?parent=8202"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/categories?post=8202"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/urbancare.clinic\/sw\/wp-json\/wp\/v2\/tags?post=8202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}