{"id":7937,"date":"2023-04-19T12:38:20","date_gmt":"2023-04-19T09:38:20","guid":{"rendered":"https:\/\/urbancare.clinic\/irregular-sleeping-habits-can-lead-to-potentially-fatal-lung-disease-study\/"},"modified":"2023-05-23T17:33:58","modified_gmt":"2023-05-23T14:33:58","slug":"tabia-zisizo-za-kawaida-za-kulala-zinaweza-kusababisha-uchunguzi-wa-magonjwa-ya-mapafu-ambayo-yanaweza-kusababisha-kifo","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/irregular-sleeping-habits-can-lead-to-potentially-fatal-lung-disease-study\/","title":{"rendered":"Tabia Isiyo ya Kawaida ya Kulala Inaweza Kusababisha Ugonjwa Wa Mapafu Unayoweza Kufa: Utafiti"},"content":{"rendered":"<p>Kutofuata ratiba ya kawaida ya kulala kunaweza kusababisha magonjwa hatari ya mapafu, utafiti mpya umegundua.<\/p>\n<p>Utafiti huo, uliochapishwa katika jarida <a rel=\"noopener nofollow\" href=\"https:\/\/www.nature.com\/articles\/s41467-023-36896-0\" target=\"_blank\">Mawasiliano ya asili<\/a>, alibainisha kuwa mifumo ya kulala isiyo ya kawaida inaweza kuathiri vibaya saa ya asili ya kibayolojia ya mwili (pia inajulikana kama saa ya circadian), ambayo inaweza kusababisha kovu kwenye mapafu au fibrosis ya mapafu, ugonjwa ambao unaweza kusababisha kifo ambapo tishu-unganishi hujilimbikiza kwenye mapafu, na kuifanya kuwa ngumu na. kusababisha ugumu wa kupumua.<\/p>\n<p>Inakuja kwa protini inayohusishwa na saa ya circadian iitwayo REV-ERB\u03b1, protini ya midundo ya circadian ambayo inadhibiti utengenezaji wa collagen mwilini. Ukosefu wa REV-ERB\u03b1 unaweza kusaidia kuongeza uzalishaji wa collagen ambayo, kwa upande wake, inaweza kusababisha ugumu wa tishu za mapafu na hatimaye fibrosis.<\/p>\n<p>Timu iliyoendesha utafiti, ikiongozwa na Irfan Rahman, Ph.D., Profesa wa Dean wa Tiba ya Mazingira katika Chuo Kikuu cha Rochester Medical Center, ilipata viwango vya chini vya REV-ERB\u03b1 na viwango vya kuongezeka kwa collagen na lysyl oxidase katika sampuli za mapafu za fibrosis ya mapafu. wagonjwa, kulingana na <a rel=\"noopener nofollow\" href=\"https:\/\/www.hindustantimes.com\/lifestyle\/health\/lung-health-is-affected-by-irregular-sleep-patterns-study-101681812485747.html\" target=\"_blank\">Nyakati za Hindustan<\/a>.<\/p>\n<p>Katika utafiti wa mfano wa panya, watafiti waligundua kuwa REV-ERB\u03b1 hubadilika-badilika siku nzima, ikifikia kilele wakati wa mchana na kushuka wakati wa usiku. Ilipopata jeraha usiku, mifano ya panya ilionyesha ongezeko kubwa la lysyl oxidase na protini za kolajeni, uharibifu mkubwa wa mapafu na viwango vya chini vya kuishi ikilinganishwa na panya waliojeruhiwa wakati wa mchana.<\/p>\n<p>Rahman alisema wafanyikazi wa zamu ya usiku wako kwenye hatari zaidi ya hali hiyo. &quot;Kazi ya zamu ya usiku kwa kawaida hutokea karibu na usiku wa manane, wakati usemi wa REV-ERB\u03b1 uko chini kabisa,&quot; alielezea. &quot;Matokeo yetu yanapendekeza kuwa kuwezesha REV-ERB\u03b1 usiku hutoa ulinzi mdogo dhidi ya uvimbe wa mapafu.&quot;<\/p>\n<p>Qixin Wang, Ph.D., mwenza wa baada ya udaktari anayefanya kazi katika maabara ya Rahman, alisema katika utafiti huo kuwa soko halina kutosha. <a href=\"https:\/\/www.medicaldaily.com\/3d-imaging-technique-pulmonary-fibrosis-lung-disease-382910\" rel=\"nofollow\">fibrosis<\/a> dawa, na kwa utafiti huo mpya, wanasayansi wanalenga kutengeneza dawa mpya za kutibu hali ya mapafu vyema.<\/p>\n<p>&quot;Kwa sasa, kuna dawa mbili tu zilizoidhinishwa na FDA kutibu fibrosis, na zinachelewesha tu mchakato huo, hazitibu ugonjwa huo,&quot; Wang alisema. &quot;Dawa zinazowasha REV-ERB\u03b1 zinaweza kutumika kama tiba inayoweza kusaidia kuzuia adilifu na kukomesha mchakato wa ugonjwa.&quot;<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><picture class=\"mapping-embed\" width=\"736\" height=\"490\"><source type=\"image\/webp\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.webp?w=736&amp;f=4b353c8bd15aeedc2e11df1d1589b9c0 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/04\/irregular-sleeping-habits-can-lead-to-potentially-fatal-lung-disease-study.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.webp?w=1100&amp;f=03619962be1fcf7e51628052d46f5219 1100w\"><source type=\"image\/jpeg\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.jpg?w=1100&amp;f=03619962be1fcf7e51628052d46f5219 1100w\"><source type=\"image\/webp\" media=\"(min-width: 480px)\" sizes=\"640px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.webp?w=640&amp;f=dc06f1e9516bd73edcc9cb88a457e479 640w\"><source type=\"image\/jpeg\" media=\"(min-width: 480px)\" sizes=\"640px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.jpg?w=640&amp;f=dc06f1e9516bd73edcc9cb88a457e479 640w\"><source type=\"image\/webp\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.webp?w=480&amp;f=33593576f0e006f0323e8740a45cf6d9 480w\"><source type=\"image\/jpeg\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.jpg?w=480&amp;f=33593576f0e006f0323e8740a45cf6d9 480w\"><source type=\"image\/webp\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/432161\/lungs.webp?w=736&amp;f=4b353c8bd15aeedc2e11df1d1589b9c0\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i432161\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/04\/irregular-sleeping-habits-can-lead-to-potentially-fatal-lung-disease-study.jpg\" alt=\"Mapafu\" width=\"736\" height=\"490\" style=\"display:none\"><\/picture><\/div><figcaption class=\"caption\">\n<span class=\"cap\">Sifa kuu za ugonjwa wa mapafu ya autoimmune ni kuvimba na makovu. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p><a href=\"https:\/\/www.medicaldaily.com\/irregular-sleeping-habits-can-lead-potentially-fatal-lung-disease-study-469458\">Chanzo cha matibabu cha kila siku<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Ukosefu wa usingizi husababisha usumbufu katika utengenezaji wa protini ya saa ya kibaolojia iitwayo REV-ERB\u03b1, ambayo inaweza kusababisha uvimbe wa mapafu.<\/p>","protected":false},"author":2,"featured_media":7938,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/04\/irregular-sleeping-habits-can-lead-to-potentially-fatal-lung-disease-study.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[203],"class_list":["post-7937","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-sleep"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - 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