{"id":7750,"date":"2023-04-05T12:21:32","date_gmt":"2023-04-05T09:21:32","guid":{"rendered":"https:\/\/urbancare.clinic\/new-shape-shifting-antibiotics-could-help-tackle-drug-resistant-viruses-researchers-suggest\/"},"modified":"2023-04-07T13:35:08","modified_gmt":"2023-04-07T10:35:08","slug":"viuavijasumu-vipya-vya-kubadilisha-umbo-vinaweza-kusaidia-kukabiliana-na-virusi-sugu-vya-watafiti-wanapendekeza","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/new-shape-shifting-antibiotics-could-help-tackle-drug-resistant-viruses-researchers-suggest\/","title":{"rendered":"Viuavijasumu Vipya vya Kubadilisha Umbo vinaweza Kusaidia Kukabiliana na Virusi vinavyostahimili Dawa, Watafiti Wanapendekeza"},"content":{"rendered":"

Kando na matukio ya mafua ya msimu, maambukizi ya bakteria na virusi yamekuwa sababu kuu ya kifo wakati wa janga hilo. Msimu wa mafua kwa ujumla huanza wakati wa vuli na hudumu hadi masika. Wakati wa mwanzo wake, wanadamu huwekwa wazi kwa idadi kubwa ya bakteria ambayo inaweza kusababisha ugonjwa mbaya.<\/p>\n

Ukali wa dalili za mafua mara nyingi husababisha matumizi ya kupita kiasi ya antibiotics, ambayo husababisha bakteria fulani kukua sugu kwao. Inaweza kufanya shambulio la bakteria kuwa ngumu zaidi kushughulikia. Kwa kuzingatia hili, Shirika la Afya Ulimwenguni lilitaja upinzani wa bakteria kama moja ya maswala ya kiafya ambayo ulimwengu unakabili hivi sasa.<\/p>\n

Hata hivyo, Profesa John E. Moses katika Maabara ya Bandari ya Cold Spring (CSHL) amefanya ugunduzi wa kustaajabisha ambao unalenga kubadilisha janga hili na kuhakikisha kwamba kunguni wanaokinza dawa hawapati tena wagonjwa bora wa mafua.<\/p>\n

Musa ametengeneza dawa ya kuua viuavijasumu inayoweza kujigeuza yenyewe kwa kupanga upya atomi zake.<\/p>\n

Wazo hilo lilimjia baada ya kuona jinsi mizinga ya kijeshi inavyofanya kazi-kuzungusha turrets zao na harakati mahiri ambayo ni reflex ya papo hapo kwa vitisho vinavyowezekana, kulingana na Habari za Hekima<\/a>. Miaka mingi baada ya kuchanganua vifaru vya kijeshi, Musa alijifunza kuhusu bullvalene\u2014molekuli inayobadilika-badilika inayojulikana na mipangilio ya kubadilishana nafasi ya atomiki. Sifa iliyosemwa ya atomi zake huipa molekuli mamilioni ya usanidi, haswa ugiligili ambao Musa alikuwa akitafuta katika utafiti wake.<\/p>\n

Kisha Moses alisoma vancomycin, dawa ya kimatibabu ambayo virusi vingi ikiwa ni pamoja na MRSA, VRSA na VRE vimekua kinga dhidi yake. Vancomycin ni kiuavijasumu chenye nguvu ambacho kimetumika kwa muda mrefu kutibu magonjwa kama vile magonjwa ya ngozi na uti wa mgongo. Moses aliamini kuwa angeweza kuboresha utendaji wa kupambana na bakteria wa dawa hiyo kwa kuichanganya na bullvalene. Wakati wa mchakato huo, aliamua kushinda tuzo ya Nobel bonyeza kemia<\/a> njia, akibainisha kuwa hufanya majibu kuwa na ufanisi zaidi kwa matumizi ya kiwango kikubwa.<\/p>\n

"Bofya kemia ni nzuri," alisema Moses, ambaye alijifunza mbinu za mbinu kutoka kwa mshindi wa Tuzo ya Nobel K. Barry Sharpless. "Inakupa uhakika na nafasi nzuri zaidi unayo ya kutengeneza vitu ngumu."<\/p>\n

Kwa msaada wa mbinu hii, Moses na wafanyakazi wenzake walikuja na dawa mpya ya kuua viuavijasumu yenye vancomycin "vichwa" viwili na kituo cha bullvalene kinachobadilikabadilika, Biospace<\/a> taarifa.<\/p>\n

Moses aliomba usaidizi wa Dk.Tatiana Soares da-Costa wa Chuo Kikuu cha Adelaide ili kupima uwezo wa dawa hiyo. Kama sehemu ya uchunguzi huo, alitoa dawa hiyo kwa vibuu vya nondo vya nta vilivyoambukizwa VRE, ambavyo hutumiwa sana kupima viuavijasumu. Matokeo yalionyesha kuwa kiuavijasumu cha kubadilisha umbo kilionyesha ahadi bora kuliko vancomycin katika kuondoa maambukizi hatari.<\/p>\n

\u201cIkiwa tunaweza kuvumbua molekuli zinazomaanisha tofauti kati ya uhai na kifo,\u201d akasema, \u201chilo lingekuwa mafanikio makubwa zaidi kuwahi kutokea.\u201d<\/p>\n

\n
\"bakteria\"<\/picture><\/div>
\nJumuiya ya wanasayansi inaendelea kutafuta matibabu madhubuti ili kupambana na upinzani unaokua wa viuavijasumu kote ulimwenguni.<\/span>
\nPixabay<\/span>
\n<\/figcaption><\/figure>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Wanasayansi walitumia mbinu ya kemia ya kubofya iliyoshinda tuzo ya Nobel kutengeneza dawa kuu ya kuua viuavijasumu.<\/p>","protected":false},"author":2,"featured_media":7751,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/04\/new-shape-shifting-antibiotics-could-help-tackle-drug-resistant-viruses-researchers-suggest.jpg","fifu_image_alt":"","footnotes":""},"categories":[27,185],"tags":[],"class_list":["post-7750","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-research-medical-articles"],"yoast_head":"\nNew Shape-Shifting Antibiotics Could Help Tackle Drug-Resistant Viruses, Researchers Suggest - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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