{"id":7481,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"kuongezeka-kwa-kasi-kwa-18f-fdg-uchukuaji-wa-radionuclide-ya-tezi-si-mara-zote-hyperthyroidism","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\/","title":{"rendered":"Kuongezeka sana kwa radionuclide ya 18F-FDG ya tezi sio kila wakati hyperthyroidism."},"content":{"rendered":"

<\/span><\/p>\n

\n

Utangulizi<\/h2>\n

Katika tathmini ya kawaida ya tezi, kupiga picha mara nyingi ni njia muhimu, ambayo inatoa sifa za anatomical na utendaji ambazo zinaweza kusaidia utambuzi. Ultrasound ya tezi ya tezi ndiyo njia kuu ya upigaji picha katika suala hili, ambapo uchunguzi wa CT, MRI na PET hauagizwi mara kwa mara kwa uchunguzi wa tezi ya tezi kupitia vidonda vya tezi mara nyingi hugunduliwa kupitia njia za juu za upigaji picha kama matokeo ya bahati mbaya.1<\/a> Tofauti na wataalamu wa radiolojia, madaktari wengi huwa hawafahamu vipengele vya radiolojia vya matatizo ya tezi yanayogunduliwa kupitia aina hizi za mwisho za skanning.2<\/a>\n<\/p>\n<\/div>\n

\n

Maelezo ya kesi<\/h2>\n

Mwanamke mwenye umri wa miaka 25 ambaye alikuwa na afya tele na asiye na dalili bila historia yoyote ya magonjwa ya matibabu au dawa za muda mrefu alikuwa amejitolea kwa utafiti wa utafiti juu ya mafuta ya kahawia. Alipitia mwili mzima 18<\/sup>Upigaji picha wa F-FDG PET\/MR kulingana na itifaki ya kawaida. Hili lilifichua bila kutarajiwa kuongezeka kwa utumiaji wa FDG kwa njia isiyo ya kawaida (SUVmax=6.84) juu ya shingo ya mbele inayokumbusha ajabu ya radionuclide ya kawaida (99m<\/sup> Tc au 131<\/sup>I) uchunguzi wa tezi ya hyperthyroidism (takwimu 1A,B<\/a>) Utambuzi ni nini, na unawezaje kuuthibitisha?<\/p>\n

\n
\n
\n
18<\/sup>F-FDG-PET scans showing diffusely increased radionuclide uptake by the thyroid gland as shown in the coronal section (A) and the sagittal section (B).<\/div><\/div>

” data-icon-position data-hide-link-title=”0″>\"Kielelezo

Kielelezo cha 1<\/span> <\/p>\n

\n18<\/sup>Michanganuo ya F-FDG-PET inayoonyesha kuongezeka kwa mionzi ya radionuclide na tezi kama inavyoonyeshwa katika sehemu ya coronal (A) na sehemu ya sagittal (B).<\/p>\n<\/div>\n<\/div>\n

Jibu: Uchunguzi wa uchunguzi wa utendakazi wa tezi ya tezi ulibaini thyroxine isiyo na seramu (FT4) ya 10.0 pmol\/L (RI: 8\u201320) na homoni ya seramu ya kuchochea tezi (TSH) ya 4.28 mIU\/L (RI: 0.45\u20134.50) . Kidokezo cha thamani kilitoka kwa mtihani wa kazi ya tezi uliofanywa miezi 7 mapema: FT4=13.2 pmol\/L (RI: 8-20) na TSH=2.43 (RI: 0.45\u20134.50). Hii ilimaanisha kushuka kwa kasi kwa FT4 kuhusishwa na ongezeko la TSH. Ultrasound ya tezi ya tezi ilifanyika, ambayo ilifunua echotexture ya jumla tofauti na hypoechogenicity ya parenchymal sambamba na thyroiditis (takwimu 2<\/a>) Kuthibitisha uchunguzi wa ultrasound, picha za MR zisizo na uzani wa T2 ambazo zilipatikana wakati huo huo wakati wa uchunguzi wa mchanganyiko wa PET-MRI zilifunua ukali wa ishara wa juu na usio na usawa ndani ya parenchyma ya tezi inayoashiria utambuzi wa Hashimoto thyroiditis.sura ya 3<\/a>) Serum antithyroid peroxidase autoantibody ilizidi 1000 IU\/mL (kawaida <50 IU\/mL), wakati serum antithyroglobulin autoantibody ilikuwa 33.55 IU\/mL (kawaida <4.1 IU\/mL). Licha ya vipimo vya 'kawaida' vya utendakazi wa tezi dume, ushahidi ulikuwa wa kuunga mkono kingamwili ya tezi inayobadilika kikamilifu sambamba na ugonjwa wa awali wa Hashimoto's thyroiditis. Mtihani mfupi wa kichocheo cha ACTH haujumuishi hypocortisolism inayoambatana, hatua muhimu ya kuzuia kuzuka kwa hali ya adsonian wakati wa kuanzishwa kwa L-thyroxine kwa wale walio na adrenalitis isiyotarajiwa kutokana na ugonjwa wa polyglandular autoimmune. Aliagizwa L-thyroxine kwa 25 \u03bcg \/ siku. Dozi iliongezwa mara mbili miaka 2 baadaye, ambayo iliboresha kiwango chake cha nishati na uzito wa mwili. Katika ziara ya kufuatilia ya miaka 4, alibaki euthyroid na serum FT4 ya 12.5 pmol\/L (RI: 8\u201316), FT3 ya 4.7 pmol\/L (RI: 3.5\u20136.0) na TSH ya 1.54 mIU\/L ( RI: 0.45\u20134.50).<\/p>\n

\n
\n
\n
Thyroid ultrasound scan revealing a gland with heterogeneous echotexture with diffuse hypo-echogenicity in bilateral lobes consistent with thyroiditis.<\/div>

” data-icon-position data-hide-link-title=”0″>\"Kielelezo

Kielelezo cha 2<\/span> <\/p>\n

Uchunguzi wa upimaji wa tezi ya tezi unaoonyesha tezi iliyo na mwangwi usio tofauti na mseto wa hypo-echogenicity katika vishikio baina ya nchi mbili sambamba na thyroiditis.<\/p>\n<\/div>\n<\/div>\n

\n
\n
\n
MRI of thyroid of the same patient, showing non-enhanced T2-weighted coronal (A) and sagittal (B) images with inhomogeneous high signal intensities within the thyroid parenchyma supportive of Hashimoto thyroiditis.<\/div>

” data-icon-position data-hide-link-title=”0″>\"Kielelezo

Kielelezo cha 3<\/span> <\/p>\n

MRI ya tezi dume ya mgonjwa yuleyule, inayoonyesha picha za coronal (A) na sagittal (B) zisizoimarishwa zenye mizani ya juu isiyofanana ndani ya parenkaima ya tezi inayounga mkono Hashimoto thyroiditis.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

\n

Hitimisho<\/h2>\n

Kuongezeka kwa maambukizi ya thyroiditis ya autoimmune pamoja na kuongezeka kwa matumizi ya 18<\/sup>Uchanganuzi wa F-FDG-PET kwa viashiria mbalimbali utaendelea kutoa matokeo ya bahati nasibu kama ilivyoangaziwa na kesi yetu.3 4<\/a> Ingawa imeongezeka sana 18<\/sup>Kuongezeka kwa tezi ya F-FDG huzingatiwa katika hyperthyroidism kama vile ugonjwa wa Graves, madaktari wanapaswa kutambua kwamba kuongezeka kwa kiasi kikubwa. 18<\/sup>Kuongezeka kwa tezi ya F-FDG kunaweza pia kuwa kutokana na Hashimoto thyroiditis,5<\/a> ambayo inatofautiana kabisa na kupungua 99m<\/sup>Tc\/131<\/sup>Mimi huchukua kawaida ya subacute thyroiditis6<\/a> na hiyo lazima itofautishwe na sifa fanani za scintigrafia za ugonjwa wa Graves unaojulikana kwa msisitizo mwingi. 99m<\/sup>Tc\/131<\/sup>Mimi na 18<\/sup>Utumiaji wa F-FDG.<\/p>\n<\/div>\n

\n

Kauli za maadili<\/h2>\n
\n

Idhini ya mgonjwa kwa uchapishaji<\/h3>\n

<\/span>Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Utangulizi<\/st> <\/p>\n

Katika tathmini ya kawaida ya tezi, kupiga picha mara nyingi ni njia muhimu, ambayo inatoa sifa za anatomical na utendaji ambazo zinaweza kusaidia utambuzi. Ultrasound ya tezi ya tezi ndiyo njia kuu ya upigaji picha katika suala hili, ambapo uchunguzi wa CT, MRI na PET hauagizwi mara kwa mara kwa uchunguzi wa tezi ya tezi kupitia vidonda vya tezi mara nyingi hugunduliwa kupitia njia za juu za upigaji picha kama matokeo ya bahati mbaya.1<\/cross-ref> Tofauti na wataalamu wa radiolojia, madaktari wengi huwa hawafahamu vipengele vya radiolojia vya matatizo ya tezi yanayogunduliwa kupitia aina hizi za mwisho za skanning.2<\/cross-ref><\/p>\n

<\/sec> Maelezo ya kesi<\/st> <\/p>\n

Mwanamke mwenye umri wa miaka 25 ambaye alikuwa na afya tele na asiye na dalili bila historia yoyote ya magonjwa ya matibabu au dawa za muda mrefu alikuwa amejitolea kwa utafiti wa utafiti juu ya mafuta ya kahawia. Alipitia mwili mzima 18<\/sup>Upigaji picha wa F-FDG PET\/MR kulingana na itifaki ya kawaida. Hili lilifichua bila kutarajiwa kuongezeka kwa utumiaji wa FDG kwa njia isiyo ya kawaida (SUVmax=6.84) juu ya shingo ya mbele inayokumbusha ajabu ya radionuclide ya kawaida (99m<\/sup>…<\/p>","protected":false},"author":2,"featured_media":7482,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism.gif","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7481","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"\nDiffusely increased 18F-FDG thyroid radionuclide uptake is not always hyperthyroidism - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/kuongezeka-kwa-kasi-kwa-18f-fdg-uchukuaji-wa-radionuclide-ya-tezi-si-mara-zote-hyperthyroidism\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Diffusely increased 18F-FDG thyroid radionuclide uptake is not always hyperthyroidism - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Introduction In the routine evaluation of the thyroid, imaging is often a useful modality, which gives anatomical and functional characteristics that can aid diagnosis. Thyroid ultrasonography is the principal imaging modality in this regard, whereas CT, MRI and PET scanning are much less frequently ordered for thyroid assessment through thyroid lesions are often discovered via such advanced imaging modalities as incidental findings.1 Unlike radiologists, most physicians tend to be unfamiliar with radiological features of thyroid disorders detected via these latter forms of scanning.2 Case description A 25-year-old woman who was otherwise overtly healthy and asymptomatic without any history of medical illnesses or chronic medications had volunteered for a research study on brown fat. She underwent whole-body 18F-FDG PET\/MR imaging according to a standard protocol. This unexpectedly revealed abnormally increased FDG uptake (SUVmax=6.84) over the anterior neck strangely reminiscent of typical radionuclide (99m...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/sw\/kuongezeka-kwa-kasi-kwa-18f-fdg-uchukuaji-wa-radionuclide-ya-tezi-si-mara-zote-hyperthyroidism\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism.gif\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"dakika 3\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Diffusely increased 18F-FDG thyroid radionuclide uptake is not always hyperthyroidism\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/\"},\"wordCount\":582,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism.gif\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"sw\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/diffusely-increased-18f-fdg-thyroid-radionuclide-uptake-is-not-always-hyperthyroidism\\\/\",\"name\":\"Diffusely increased 18F-FDG thyroid radionuclide uptake is not always hyperthyroidism - 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