{"id":7081,"date":"2022-12-29T13:12:32","date_gmt":"2022-12-29T10:12:32","guid":{"rendered":"https:\/\/www.medicaldaily.com\/scientists-develop-blood-test-alzheimers-diagnosis-467657"},"modified":"2022-12-29T13:12:32","modified_gmt":"2022-12-29T10:12:32","slug":"wanasayansi-hutengeneza-mtihani-wa-damu-kwa-utambuzi-wa-alzheimer","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/scientists-develop-blood-test-for-alzheimers-diagnosis\/","title":{"rendered":"Wanasayansi Watengeneza Mtihani wa Damu kwa Utambuzi wa Alzeima"},"content":{"rendered":"
<\/div>\n

Wanasayansi wameunda mtihani mkali wa damu ili kugundua ugonjwa wa Alzeima. Kipimo hiki cha damu kinaripotiwa kuwa na makali zaidi ya vipimo vingine vya damu katika uwanja huo.<\/p>\n

Alzheimer's ni ugonjwa wa neurodegenerative na ni aina ya kawaida ya shida ya akili, lakini utambuzi wake ni changamoto, hasa wakati wa mwanzo wa ugonjwa huo.<\/p>\n

Kwa utambuzi wa mafanikio, ugunduzi wa alama tatu tofauti unapendekezwa. Hizi ni pamoja na mrundikano usio wa kawaida wa amiloidi na protini za tau, pamoja na upotevu wa polepole na unaoendelea wa seli za niuroni katika maeneo maalum ya ubongo.<\/p>\n

Hivi sasa, utambuzi wa ugonjwa wa Alzeima unahusisha upigaji picha wa ubongo ghali na kuchomwa kwa lumbar kwa uchungu, kama inavyosema Mlezi<\/a>. Kwa hiyo, haja ya uchunguzi rahisi wa mtihani wa damu ni dhahiri.<\/p>\n

<\/div>\n

Picha ya ubongo sio tu ya gharama kubwa, lakini ina muda mrefu wa kusubiri kwa ratiba.<\/p>\n

"Wagonjwa wengi, hata huko Amerika, hawana ufikiaji wa MRI na skana za PET. Ufikivu ni suala kuu,\u201d Prof Thomas Karikari katika Chuo Kikuu cha Pittsburgh, Pennsylvania, Marekani, mwandishi mwenza wa utafiti uliochapishwa katika jarida hilo. Ubongo<\/a>, sema.<\/p>\n

Kuchomwa kwa lumbar ni utaratibu unaoumiza sana ambao hutumiwa kutoa maji ya cerebrospinal (CSF) kutoka kwenye uti wa mgongo. Mtu anaweza hata kuonyesha maumivu ya kichwa au maumivu ya mgongo kufuatia utaratibu.<\/p>\n

Mbali na kutokuwa na uchungu na kupatikana kwa urahisi, vipimo vya damu pia vitasaidia katika kugundua ugonjwa huo mapema, ambayo, kwa upande wake, itasababisha kuanza kwa matibabu mapema.<\/p>\n

"Kipimo cha damu ni cha bei nafuu, salama, na ni rahisi zaidi kusimamia, na kinaweza kuboresha imani ya kimatibabu katika kuchunguza Alzheimers na kuchagua washiriki kwa ajili ya majaribio ya kimatibabu na ufuatiliaji wa magonjwa," Karikari alisema, chombo kiliripoti.<\/p>\n

Ingawa vipimo vya sasa vya damu vinaweza kugundua viwango visivyo vya kawaida vya amiloidi na protini za tau, kubaini viashirio vya uharibifu wa seli za neva maalum kwa ubongo kumeonekana kuwa vigumu. Hapa ndipo kipimo cha damu kilichotengenezwa na Karikari na timu yake kinapotofautiana. Timu ya utafiti imeunda kipimo cha damu kinachotegemea kingamwili ambacho hutambua aina fulani ya protini ya tau inayoitwa tau inayotokana na ubongo. Protini hii ni maalum kwa ugonjwa wa Alzheimer's.<\/p>\n

Kwa utafiti huo, watafiti walijaribu wagonjwa 600 wanaougua hatua tofauti za Alzheimer's. Waligundua kuwa viwango vya tau inayotokana na ubongo vililingana na viwango vya tau katika CSF. Pia, kipimo cha damu kinaweza kutofautisha Alzheimers na magonjwa mengine ya mfumo wa neva.<\/p>\n

Viwango vya protini pia vilionyesha uhusiano mkubwa na ukali wa alama za amiloidi na tangles kwenye tishu za ubongo zilizochukuliwa kutoka kwa watu waliokufa kutokana na Alzheimer's, utafiti uligundua.<\/p>\n

Kufuatilia viwango vya tau inayotokana na ubongo katika damu kunaweza kusaidia kuunda majaribio ya kimatibabu ya ufanisi kwa ajili ya matibabu ya Alzeima, Karikari alitumai.<\/p>\n

Utafiti tofauti umegundua adimu, lahaja za kijeni zinazoharibu<\/a> ambayo huongeza hatari ya ugonjwa wa Alzheimer's.<\/p>\n

"Matokeo yetu hutoa ushahidi wa ziada kwa jukumu kubwa la usindikaji wa protini ya amyloid-\u03b2 mtangulizi, mkusanyiko wa amyloid-\u03b2, kimetaboliki ya lipid, na kazi ya microglial katika AD," waandishi waliandika katika karatasi yao.<\/p>\n

Kwa kutumia uchanganuzi wa mzigo unaotegemea jeni badala ya tafiti za kawaida za muungano wa jenomu kote (GWAS), watafiti waligundua uhusiano mkubwa kati ya vibadala adimu, vinavyodhuru katika ATP8B4 na ABCA1 vyenye hatari ya AD, na ishara katika ADAM10, na vile vile nadra. -Lahaja mzigo katika jeni RIN3, CLU, ZCWPW1 na ACE, kulingana na GenEngNews.<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

"Kipimo cha damu ni cha bei nafuu, salama, na ni rahisi zaidi kusimamia, na kinaweza kuboresha imani ya kimatibabu katika kutambua Alzheimers na kuchagua washiriki kwa ajili ya majaribio ya kimatibabu na ufuatiliaji wa magonjwa," Prof Thomas Karikari alisema.<\/p>","protected":false},"author":2,"featured_media":7082,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/12\/scientists-develop-blood-test-for-alzheimers-diagnosis.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-7081","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nScientists Develop Blood Test For Alzheimer's Diagnosis - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/sw\/wanasayansi-hutengeneza-mtihani-wa-damu-kwa-utambuzi-wa-alzheimer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists Develop Blood Test For Alzheimer's Diagnosis - 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