{"id":7051,"date":"2022-12-23T12:51:18","date_gmt":"2022-12-23T09:51:18","guid":{"rendered":"https:\/\/www.medicaldaily.com\/common-acne-treatment-adolescents-can-have-long-term-effects-skeletal-system-467625"},"modified":"2022-12-23T12:51:18","modified_gmt":"2022-12-23T09:51:18","slug":"matibabu-ya-chunusi-ya-kawaida-kwa-vijana-yanaweza-kuwa-na-athari-za-muda-mrefu-kwenye-utafiti-wa-mfumo-wa-mifupa","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/sw\/common-acne-treatment-in-adolescents-can-have-long-term-effects-on-skeletal-system-study\/","title":{"rendered":"Matibabu ya Chunusi ya Kawaida Katika Vijana Inaweza Kuwa na Athari za Muda Mrefu kwenye Mfumo wa Mifupa: Utafiti"},"content":{"rendered":"
<\/div>\n

Vijana walio na chunusi wanaweza kuhitaji kufikiria mara mbili kabla ya kuanza matibabu ya kawaida ya viuavijasumu ili kusuluhisha maswala ya ngozi. Utafiti mpya umegundua kuwa matibabu ya antibiotiki yanaweza kubadilisha mfumo wa mifupa na athari za kudumu.<\/p>\n

Utafiti huo, uliochapishwa katika Journal of Clinical Investigation (JCI) Insight<\/a>, ilionyesha kuwa matumizi ya muda mrefu ya antibiotic ya utaratibu, minocycline, inaweza kuwa na athari zisizotarajiwa wakati wa ukuaji wa mfupa wa kijana.<\/p>\n

Matibabu ya Minocycline inaweza kudumu hadi miaka miwili. Antibiotics hii hubadilisha microbiome ya gut-idadi ya microorganisms wanaoishi kwenye utumbo.<\/p>\n

Watafiti kutoka Chuo Kikuu cha Matibabu cha South Carolina (MUSC) walipata uwiano mkubwa kati ya muundo wa microbiome ya utumbo na kukomaa kwa mifupa yenye afya.<\/p>\n

<\/div>\n

Kwa ajili ya utafiti, timu ya utafiti ilitoa dozi ifaayo ya minocycline kwa panya wakati wa hatua ya kubalehe\/baada ya kubalehe, ambayo ni umri sawa wa ujana kwa binadamu.<\/p>\n

Ilibainika katika utafiti kwamba ingawa tiba ya minocycline haikusababisha madhara yoyote ya cytotoxic au kusababisha majibu ya uchochezi, ilibadilisha muundo wa microbiome ya utumbo ambayo ilisababisha kupungua kwa ukomavu wa mifupa na usio na ufanisi wa mifupa.<\/p>\n

"Kuna mabadiliko endelevu kwa microbiome ya matumbo kufuatia tiba ya muda mrefu ya utaratibu wa minocycline ambayo inasababisha kupunguzwa kwa ukomavu wa mfupa," mwandishi wa kwanza, Matthew Carson, maabara ya Novice, alisema. SciTechDaily<\/a>.<\/p>\n

"Kwa mtazamo wa kimatibabu, sio tu kwamba matibabu ya minocycline husababisha mabadiliko kwa mifupa inayokomaa, mikrobiome na mifupa haiwezi kupona kikamilifu baada ya tiba ya viuavijasumu," Chad Novince, mpelelezi mkuu na profesa msaidizi katika Idara ya Sayansi ya Afya ya Kinywa. katika Chuo cha Tiba ya Meno imeongezwa.<\/p>\n

Minocycline ni ya darasa la tetracycline la antibiotics. Kundi hili pia linajumuisha antibiotics kama vile tetracycline, doxycycline, na sarecycline. Antibiotics hizi hufanya kazi kwa kuzuia ukuaji na kuenea kwa bakteria. Katika kesi ya chunusi<\/a>, huua bakteria wanaoambukiza vinyweleo na kupunguza baadhi ya vitu vya asili vya mafuta vinavyosababisha chunusi.<\/p>\n

"Kinachovutia sana ni ikiwa unasababisha mabadiliko kwa mikrobiome wakati wa kipindi hiki cha ujana wakati mikrobiota yako bado inaendelea kuelekea hali ya watu wazima thabiti, utakuwa na madhara makubwa kwenye mifupa inayokomaa," Carson alisema, kulingana na kituo hicho.<\/p>\n

Inashangaza, timu iligundua kuwa mabadiliko katika microbiome ya gut kutokana na minocycline pia yaliathiri mawasiliano kati ya ini na utumbo mdogo, ambayo hufanyika kupitia molekuli zinazoitwa bile asidi.<\/p>\n

"Asidi za bile hazikuwa zimezingatiwa hapo awali kama molekuli muhimu za mawasiliano kati ya utumbo na mifupa," Novence alisema, kulingana na duka hilo. "Kwa kubadilisha microbiome ya utumbo, muundo wa asidi ya bile hubadilishwa, ambayo huathiri fiziolojia ya mwenyeji, pamoja na kukomaa kwa mifupa."<\/p>\n

Microbiome ya utumbo iliyobadilishwa iliunda dimbwi tofauti la asidi ya bile. Aina hizi tofauti za asidi ya bile hazikuweza kuamsha seli zinazounda mfupa zinazoitwa osteoblasts, ambazo, kwa upande wake, zilipunguza uundaji wa mfupa na madini kwa zaidi ya 30%.<\/p>\n

"Hii ilikuwa sayansi shirikishi, ambapo nadhani tuko leo," Novence alisema. "Ili kuendesha sayansi yenye athari kubwa, unahitaji kuleta wataalam kutoka fani na taaluma tofauti. Tulikuwa na bahati ya kuwa na timu yenye nguvu sana. Ilikuwa ya kufurahisha - jambo lote lilikuwa la kusisimua!"<\/p>\n

Chanzo cha matibabu cha kila siku<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Ilibainika katika utafiti kwamba tiba ya minocycline ilibadilisha muundo wa microbiome ya gut ambayo ilisababisha kupungua kwa ukomavu wa mifupa na usio na ufanisi wa ukomavu wa mifupa.<\/p>","protected":false},"author":2,"featured_media":7052,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/12\/common-acne-treatment-in-adolescents-can-have-long-term-effects-on-skeletal-system-study.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-7051","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nCommon Acne Treatment In Adolescents Can Have Long-Term Effects On Skeletal System: Study - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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