{"id":7608,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer\/"},"modified":"2023-05-23T17:38:32","modified_gmt":"2023-05-23T14:38:32","slug":"%d0%bd%d0%b8%d0%b7%d0%ba%d0%b8%d0%b9-%d1%83%d1%80%d0%be%d0%b2%d0%b5%d0%bd%d1%8c-%d1%84%d0%b0%d0%ba%d1%82%d0%be%d1%80%d0%b0-%d0%ba%d0%be%d0%bc%d0%bf%d0%bb%d0%b5%d0%bc%d0%b5%d0%bd%d1%82%d0%b0-h-%d1%83","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/ru\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer\/","title":{"rendered":"\u041d\u0438\u0437\u043a\u0438\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0444\u0430\u043a\u0442\u043e\u0440\u0430 \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430 H \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442 \u0440\u0438\u0441\u043a \u0441\u043c\u0435\u0440\u0442\u0438 \u043e\u0442 \u0440\u0430\u043a\u0430 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u043c\u0435\u043b\u043a\u043e\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u044b\u043c \u0440\u0430\u043a\u043e\u043c \u043b\u0435\u0433\u043a\u043e\u0433\u043e"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>\u0415\u0441\u043b\u0438 \u0432\u044b \u0445\u043e\u0442\u0438\u0442\u0435 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u043e \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u0442\u044c \u0447\u0430\u0441\u0442\u044c \u0438\u043b\u0438 \u0432\u0441\u044e \u044d\u0442\u0443 \u0441\u0442\u0430\u0442\u044c\u044e, \u0432\u043e\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0439\u0442\u0435\u0441\u044c \u043f\u0440\u0438\u0432\u0435\u0434\u0435\u043d\u043d\u043e\u0439 \u043d\u0438\u0436\u0435 \u0441\u0441\u044b\u043b\u043a\u043e\u0439, \u043a\u043e\u0442\u043e\u0440\u0430\u044f \u043f\u0440\u0438\u0432\u0435\u0434\u0435\u0442 \u0432\u0430\u0441 \u043a \u0441\u043b\u0443\u0436\u0431\u0435 RightsLink \u0426\u0435\u043d\u0442\u0440\u0430 \u0437\u0430\u0449\u0438\u0442\u044b \u0430\u0432\u0442\u043e\u0440\u0441\u043a\u0438\u0445 \u043f\u0440\u0430\u0432. \u0412\u044b \u0441\u043c\u043e\u0436\u0435\u0442\u0435 \u043f\u043e\u043b\u0443\u0447\u0438\u0442\u044c \u0431\u044b\u0441\u0442\u0440\u0443\u044e \u0446\u0435\u043d\u0443 \u0438 \u043c\u0433\u043d\u043e\u0432\u0435\u043d\u043d\u043e\u0435 \u0440\u0430\u0437\u0440\u0435\u0448\u0435\u043d\u0438\u0435 \u043d\u0430 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u043e\u0435 \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u043d\u0438\u0435 \u043a\u043e\u043d\u0442\u0435\u043d\u0442\u0430 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u043c\u0438 \u0441\u043f\u043e\u0441\u043e\u0431\u0430\u043c\u0438.<\/p>\n<p><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/919?rss=1\">\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0435\u0436\u0435\u0434\u043d\u0435\u0432\u043d\u044b\u0439 \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p><sec><st>\u0412\u0432\u0435\u0434\u0435\u043d\u0438\u0435<\/st><\/p>\n<p>\u0420\u0430\u043a \u043b\u0435\u0433\u043a\u0438\u0445 \u2014 \u044d\u0442\u043e \u0440\u0430\u0437\u043d\u043e\u0432\u0438\u0434\u043d\u043e\u0441\u0442\u044c \u0433\u043b\u0443\u0431\u043e\u043a\u043e \u0438\u043d\u0432\u0430\u0437\u0438\u0432\u043d\u043e\u0439 \u043e\u043f\u0443\u0445\u043e\u043b\u0438, \u043a\u043e\u0442\u043e\u0440\u0443\u044e \u0442\u0440\u0443\u0434\u043d\u043e \u043b\u0435\u0447\u0438\u0442\u044c, \u0430 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0441\u043c\u0435\u0440\u0442\u043d\u043e\u0441\u0442\u0438 \u043e\u0442 \u043d\u0435\u0435 \u0432\u044b\u0441\u043e\u043a. \u041f\u0440\u0435\u0434\u044b\u0434\u0443\u0449\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438, \u0447\u0442\u043e \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430 \u043c\u043e\u0436\u0435\u0442 \u0441\u043f\u043e\u0441\u043e\u0431\u0441\u0442\u0432\u043e\u0432\u0430\u0442\u044c \u043f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044e \u043d\u0435\u043c\u0435\u043b\u043a\u043e\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0433\u043e \u0440\u0430\u043a\u0430 \u043b\u0435\u0433\u043a\u0438\u0445 (\u041c\u0420\u041b). \u041e\u0434\u043d\u0430\u043a\u043e \u043f\u043e SCLC \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e \u043c\u0430\u043b\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439.<\/p>\n<p><\/sec><br \/>\n<sec><st>\u041c\u0435\u0442\u043e\u0434\u044b<\/st><\/p>\n<p>\u0424\u0430\u043a\u0442\u043e\u0440 \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430 H (CFH), \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u044b C3, \u0430 \u0442\u0430\u043a\u0436\u0435 C4 \u0438\u0437\u043c\u0435\u0440\u044f\u043b\u0438\u0441\u044c \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432, \u0430 \u043f\u0440\u043e\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0432\u043b\u0438\u044f\u043d\u0438\u0435 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u0445 \u043f\u0430\u0440\u0430\u043c\u0435\u0442\u0440\u043e\u0432 \u043e\u0446\u0435\u043d\u0438\u0432\u0430\u043b\u043e\u0441\u044c \u0441 \u043f\u043e\u043c\u043e\u0449\u044c\u044e \u043b\u043e\u0433-\u0440\u0430\u043d\u0433\u043e\u0432\u043e\u0433\u043e \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0430\u043d\u0430\u043b\u0438\u0437\u0430 \u0438 \u043c\u043d\u043e\u0433\u043e\u0444\u0430\u043a\u0442\u043e\u0440\u043d\u044b\u0445 \u043c\u043e\u0434\u0435\u043b\u0435\u0439 \u041a\u043e\u043a\u0441\u0430. \u041a\u0440\u043e\u043c\u0435 \u0442\u043e\u0433\u043e, \u043c\u044b \u043f\u043e\u0441\u0442\u0440\u043e\u0438\u043b\u0438 \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u0443\u044e\u0449\u0443\u044e \u043c\u043e\u0434\u0435\u043b\u044c \u043d\u0430 \u043e\u0441\u043d\u043e\u0432\u0435 \u0444\u0440\u0430\u043a\u0446\u0438\u0439 \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430 \u0438 \u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0434\u0438\u043b\u0438 \u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c \u043c\u043e\u0434\u0435\u043b\u0438.<\/p>\n<p><\/sec><br \/>\n<sec><st>\u041f\u043e\u043b\u0443\u0447\u0435\u043d\u043d\u044b\u0435 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b<\/st><\/p>\n<p>\u0421\u0440\u0435\u0434\u0438 \u044d\u0442\u0438\u0445 242 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 200 (82,6%) \u0443\u043c\u0435\u0440\u043b\u0438. \u0421\u0440\u0435\u0434\u043d\u0435\u0435 \u0432\u0440\u0435\u043c\u044f \u0432\u044b\u0436\u0438\u0432\u0430\u043d\u0438\u044f \u0441\u043e\u0441\u0442\u0430\u0432\u0438\u043b\u043e 18,3 \u043c\u0435\u0441\u044f\u0446\u0430. \u0421 \u043f\u043e\u043c\u043e\u0449\u044c\u044e \u043c\u043d\u043e\u0433\u043e\u0444\u0430\u043a\u0442\u043e\u0440\u043d\u043e\u0433\u043e \u0430\u043d\u0430\u043b\u0438\u0437\u0430 \u043c\u044b \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0438\u043b\u0438, \u0447\u0442\u043e \u0432\u044b\u0441\u043e\u043a\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u0438 CFH \u0441\u043d\u0438\u0436\u0430\u044e\u0442 \u0440\u0438\u0441\u043a \u0441\u043c\u0435\u0440\u0442\u0438 (HR 0,23, 95% CI \u043e\u0442 0,10 \u0434\u043e 0,57, p&lt;0,001), \u0432 \u0442\u043e \u0432\u0440\u0435\u043c\u044f \u043a\u0430\u043a \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430 C4 \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u0435\u0442 \u043f\u043b\u043e\u0445\u043e\u0439 \u043f\u0440\u043e\u0433\u043d\u043e\u0437 (HR 2,28, 95% CI \u043e\u0442 1,66 \u0434\u043e 3,13, p&lt;0,001). ). \u041c\u044b \u043f\u0440\u043e\u0432\u0435\u0440\u0438\u043b\u0438 \u043f\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0435 \u0441 \u043f\u043e\u043c\u043e\u0449\u044c\u044e \u043c\u043e\u0434\u0435\u043b\u0435\u0439 \u041a\u043e\u043a\u0441\u0430 \u0438 \u043f\u043e\u0441\u0442\u0440\u043e\u0438\u043b\u0438 \u043c\u043e\u0434\u0435\u043b\u0438 \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u043d\u0430 \u043e\u0441\u043d\u043e\u0432\u0435 CFH \u0434\u043b\u044f \u043f\u043e\u0441\u0442\u0440\u043e\u0435\u043d\u0438\u044f \u043d\u043e\u043c\u043e\u0433\u0440\u0430\u043c\u043c\u044b \u043f\u0443\u0442\u0435\u043c \u0432\u043d\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439 \u043f\u0440\u043e\u0432\u0435\u0440\u043a\u0438. \u041d\u043e\u043c\u043e\u0433\u0440\u0430\u043c\u043c\u0430 \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0430 \u043f\u0440\u0435\u0432\u043e\u0441\u0445\u043e\u0434\u043d\u0443\u044e \u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c \u043e\u0446\u0435\u043d\u043a\u0438 \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e\u0441\u0442\u0438 \u0441\u043c\u0435\u0440\u0442\u0438, \u0434\u0430\u0432 \u0441\u043a\u043e\u0440\u0440\u0435\u043a\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u0443\u044e C-\u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u043a\u0443 0,905.<\/p>\n<p><\/sec><br \/>\n<sec><st>\u0412\u044b\u0432\u043e\u0434\u044b<\/st><\/p>\n<p>CFH \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u043f\u0440\u0438\u0437\u043d\u0430\u043d \u0431\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440\u043e\u043c \u0434\u043b\u044f \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0440\u0438\u0441\u043a\u0430 \u0441\u043c\u0435\u0440\u0442\u0438 \u043f\u0440\u0438 \u041c\u0420\u041b. \u041c\u043e\u0434\u0435\u043b\u044c \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f, \u0441\u043e\u0437\u0434\u0430\u043d\u043d\u0430\u044f \u043d\u0430 \u043e\u0441\u043d\u043e\u0432\u0435 \u0443\u0440\u043e\u0432\u043d\u0435\u0439 CFH, C3 \u0438 C4, \u0438\u043c\u0435\u0435\u0442 \u0445\u043e\u0440\u043e\u0448\u0443\u044e \u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c \u043f\u0440\u0438 \u043f\u0440\u043e\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043e\u0446\u0435\u043d\u043a\u0435 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432.<\/p>\n<p><\/sec><\/p>","protected":false},"author":2,"featured_media":7609,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[150],"class_list":["post-7608","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles","tag-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Low level of complement factor H increases the risk of cancer-related death in patients with small-cell lung cancer - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/ru\/\u043d\u0438\u0437\u043a\u0438\u0439-\u0443\u0440\u043e\u0432\u0435\u043d\u044c-\u0444\u0430\u043a\u0442\u043e\u0440\u0430-\u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430-h-\u0443\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Low level of complement factor H increases the risk of cancer-related death in patients with small-cell lung cancer - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Introduction Pulmonary cancer is a kind of deeply invasive tumour which is difficult to treat, and its mortality rate is high. Previous research has shown that activation of complement could contribute to the progression of non-small-cell lung cancer (SCLC). However, little research has been done on SCLC. Methods Complement factor H (CFH), complements C3 as well as C4 were measured in patients, and the prognostic impact of different parameters was assessed by log-rank function analysis and Cox multifactor models. Besides, we constructed a predictive model based on complement fractions and validated the accuracy of the model. Results Among these 242 patients, 200 (82.6%) died. The median survival time was 18.3 months. We found by multifactorial analysis that high levels of CFH decreased the risk of death (HR 0.23, 95% CI 0.10 to 0.57, p&lt;0.001), while elevated complement C4 displayed poor prognosis (HR 2.28, 95% CI 1.66 to 3.13, p&lt;0.001). We screened variables by Cox models and constructed CFH-based prediction models to plot a nomogram by internal validation. The nomogram showed excellent accuracy in assessing the probability of death, yielding an adjusted C-statistics of 0.905. Conclusions CFH can be recognised as a biomarker to predict the risk of death in SCLC. The prediction model established based on CFH, C3 and C4 levels has good accuracy in patients&#039; prognostic assessment.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/ru\/\u043d\u0438\u0437\u043a\u0438\u0439-\u0443\u0440\u043e\u0432\u0435\u043d\u044c-\u0444\u0430\u043a\u0442\u043e\u0440\u0430-\u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430-h-\u0443\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-23T14:38:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer.jpg\" \/>\n\t<meta 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\u0441\u043c\u0435\u0440\u0442\u0438 \u043e\u0442 \u0440\u0430\u043a\u0430 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u043c\u0435\u043b\u043a\u043e\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u044b\u043c \u0440\u0430\u043a\u043e\u043c \u043b\u0435\u0433\u043a\u0438\u0445 - Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/ru\/\u043d\u0438\u0437\u043a\u0438\u0439-\u0443\u0440\u043e\u0432\u0435\u043d\u044c-\u0444\u0430\u043a\u0442\u043e\u0440\u0430-\u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430-h-\u0443\/","og_locale":"ru_RU","og_type":"article","og_title":"Low level of complement factor H increases the risk of cancer-related death in patients with small-cell lung cancer - Urban Care Clinic","og_description":"Introduction Pulmonary cancer is a kind of deeply invasive tumour which is difficult to treat, and its mortality rate is high. Previous research has shown that activation of complement could contribute to the progression of non-small-cell lung cancer (SCLC). However, little research has been done on SCLC. Methods Complement factor H (CFH), complements C3 as well as C4 were measured in patients, and the prognostic impact of different parameters was assessed by log-rank function analysis and Cox multifactor models. Besides, we constructed a predictive model based on complement fractions and validated the accuracy of the model. Results Among these 242 patients, 200 (82.6%) died. The median survival time was 18.3 months. We found by multifactorial analysis that high levels of CFH decreased the risk of death (HR 0.23, 95% CI 0.10 to 0.57, p&lt;0.001), while elevated complement C4 displayed poor prognosis (HR 2.28, 95% CI 1.66 to 3.13, p&lt;0.001). We screened variables by Cox models and constructed CFH-based prediction models to plot a nomogram by internal validation. The nomogram showed excellent accuracy in assessing the probability of death, yielding an adjusted C-statistics of 0.905. Conclusions CFH can be recognised as a biomarker to predict the risk of death in SCLC. The prediction model established based on CFH, C3 and C4 levels has good accuracy in patients' prognostic assessment.","og_url":"https:\/\/urbancare.clinic\/ru\/\u043d\u0438\u0437\u043a\u0438\u0439-\u0443\u0440\u043e\u0432\u0435\u043d\u044c-\u0444\u0430\u043a\u0442\u043e\u0440\u0430-\u043a\u043e\u043c\u043f\u043b\u0435\u043c\u0435\u043d\u0442\u0430-h-\u0443\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2022-11-22T10:00:22+00:00","article_modified_time":"2023-05-23T14:38:32+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/low-level-of-complement-factor-h-increases-the-risk-of-cancer-related-death-in-patients-with-small-cell-lung-cancer.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"\u041d\u0430\u043f\u0438\u0441\u0430\u043d\u043e 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