{"id":7457,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/claustrum-hyperintensity-as-a-marker-of-anti-nmdar-encephalitis\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"%d0%b3%d0%b8%d0%bf%d0%b5%d1%80%d0%b8%d0%bd%d1%82%d0%b5%d0%bd%d1%81%d0%b8%d0%b2%d0%bd%d0%be%d1%81%d1%82%d1%8c-%d0%ba%d0%bb%d0%b0%d1%83%d1%81%d1%82%d1%80%d1%83%d0%bc%d0%b0-%d0%ba%d0%b0%d0%ba-%d0%bc","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/ru\/claustrum-hyperintensity-as-a-marker-of-anti-nmdar-encephalitis\/","title":{"rendered":"\u0413\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0443\u043c\u0430 \u043a\u0430\u043a \u043c\u0430\u0440\u043a\u0435\u0440 \u0430\u043d\u0442\u0438-NMDAR-\u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442\u0430"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/claustrum-hyperintensity-as-a-marker-of-anti-nmdar-encephalitis.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">\u041c\u043e\u043b\u043e\u0434\u043e\u0439 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0439 \u043f\u0430\u0446\u0438\u0435\u043d\u0442 \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043f\u043e\u043b\u0430 \u0441 \u043f\u043e\u0434\u043e\u0441\u0442\u0440\u044b\u043c \u043d\u0430\u0447\u0430\u043b\u043e\u043c, \u0431\u044b\u0441\u0442\u0440\u043e \u043f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u0443\u044e\u0449\u0438\u043c\u0438 \u043a\u043e\u0433\u043d\u0438\u0442\u0438\u0432\u043d\u044b\u043c\u0438 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u043c\u0438 \u0438 \u0440\u0435\u0444\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u044b\u043c\u0438 \u0441\u0443\u0434\u043e\u0440\u043e\u0433\u0430\u043c\u0438, \u0443 \u043a\u043e\u0442\u043e\u0440\u043e\u0433\u043e \u0431\u044b\u043b \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d \u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442 \u0441 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u043d\u044b\u043c\u0438 \u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430\u043c\u0438 \u043f\u0440\u043e\u0442\u0438\u0432 N-\u043c\u0435\u0442\u0438\u043b-D-\u0430\u0441\u043f\u0430\u0440\u0442\u0430\u0442\u043d\u043e\u0433\u043e \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0430 (\u0430\u043d\u0442\u0438-NMDAR) \u0432 \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0438\u0438 \u0441 \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u044f\u043c\u0438 \u0413\u0440\u0430\u0443\u0441\u0430. <em>\u0438 \u0434\u0440\u0443\u0433\u0438\u0435.<\/em> (2016) \u043f\u043e\u0441\u043b\u0435 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u044f \u0432\u0438\u043d\u043e\u0432\u043d\u044b\u0445 \u0430\u0443\u0442\u043e\u0430\u043d\u0442\u0438\u0442\u0435\u043b \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435.<span class=\"xref-bibr\">1<\/span> \u041c\u0420\u0422 \u0433\u043e\u043b\u043e\u0432\u043d\u043e\u0433\u043e \u043c\u043e\u0437\u0433\u0430 \u0432\u044b\u044f\u0432\u0438\u043b\u0430 \u0431\u0438\u043b\u0430\u0442\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0435 \u04222-\u0432\u0437\u0432\u0435\u0448\u0435\u043d\u043d\u043e\u0435 \u0438\u0437\u043e\u0431\u0440\u0430\u0436\u0435\u043d\u0438\u0435 (T2WI)\/\u0433\u0438\u0434\u0440\u0430\u0432\u043b\u0438\u0447\u0435\u0441\u043a\u0438 \u043e\u0441\u043b\u0430\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0438\u043d\u0432\u0435\u0440\u0441\u043d\u043e\u0435 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u0435 (FLAIR) \u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0443\u043c\u0430 (\u0440\u0438\u0441. 1). \u0420\u0430\u043d\u0435\u0435 \u0432 \u043a\u043e\u0433\u043e\u0440\u0442\u0435 \u0438\u0437 34 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432<span class=\"xref-bibr\">2<\/span> \u0441 \u0432\u043f\u0435\u0440\u0432\u044b\u0435 \u0432\u043e\u0437\u043d\u0438\u043a\u0448\u0435\u0439 \u0440\u0435\u0444\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u043e\u0439 \u044d\u043f\u0438\u043b\u0435\u043f\u0441\u0438\u0435\u0439, \u0443 4 \u0438\u0437 34 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043d\u0430 \u041c\u0420\u0422 \u0431\u044b\u043b\u0430 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0430 \u0434\u0432\u0443\u0441\u0442\u043e\u0440\u043e\u043d\u043d\u044f\u044f \u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u044c FLAIR \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0443\u043c\u0430, \u043d\u0438 \u0443 \u043e\u0434\u043d\u043e\u0433\u043e \u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e24?rss=1\">\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0435\u0436\u0435\u0434\u043d\u0435\u0432\u043d\u044b\u0439 \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>\u041c\u043e\u043b\u043e\u0434\u043e\u0439 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0439 \u043f\u0430\u0446\u0438\u0435\u043d\u0442 \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043f\u043e\u043b\u0430 \u0441 \u043f\u043e\u0434\u043e\u0441\u0442\u0440\u044b\u043c \u043d\u0430\u0447\u0430\u043b\u043e\u043c, \u0431\u044b\u0441\u0442\u0440\u043e \u043f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u0443\u044e\u0449\u0438\u043c\u0438 \u043a\u043e\u0433\u043d\u0438\u0442\u0438\u0432\u043d\u044b\u043c\u0438 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u043c\u0438 \u0438 \u0440\u0435\u0444\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u044b\u043c\u0438 \u0441\u0443\u0434\u043e\u0440\u043e\u0433\u0430\u043c\u0438, \u0443 \u043a\u043e\u0442\u043e\u0440\u043e\u0433\u043e \u0431\u044b\u043b \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d \u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442 \u0441 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u043d\u044b\u043c\u0438 \u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430\u043c\u0438 \u043f\u0440\u043e\u0442\u0438\u0432 N-\u043c\u0435\u0442\u0438\u043b-D-\u0430\u0441\u043f\u0430\u0440\u0442\u0430\u0442\u043d\u043e\u0433\u043e \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0430 (\u0430\u043d\u0442\u0438-NMDAR) \u0432 \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0438\u0438 \u0441 \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u044f\u043c\u0438 \u0413\u0440\u0430\u0443\u0441\u0430. <i>\u0438 \u0434\u0440\u0443\u0433\u0438\u0435.<\/i> (2016) \u043f\u043e\u0441\u043b\u0435 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u044f \u0432\u0438\u043d\u043e\u0432\u043d\u044b\u0445 \u0430\u0443\u0442\u043e\u0430\u043d\u0442\u0438\u0442\u0435\u043b \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref> \u041c\u0420\u0422 \u0433\u043e\u043b\u043e\u0432\u043d\u043e\u0433\u043e \u043c\u043e\u0437\u0433\u0430 \u0432\u044b\u044f\u0432\u0438\u043b\u0430 \u0434\u0432\u0443\u0441\u0442\u043e\u0440\u043e\u043d\u043d\u0435\u0435 \u04222-\u0432\u0437\u0432\u0435\u0448\u0435\u043d\u043d\u043e\u0435 \u0438\u0437\u043e\u0431\u0440\u0430\u0436\u0435\u043d\u0438\u0435 (T2WI)\/\u0438\u043d\u0432\u0435\u0440\u0441\u0438\u043e\u043d\u043d\u043e\u0435 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u0435 \u0441 \u043e\u0441\u043b\u0430\u0431\u043b\u0435\u043d\u0438\u0435\u043c \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438 (FLAIR) \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0430\u043b\u044c\u043d\u043e\u0439 \u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u0438 (<cross-ref type=\"fig\" refid=\"F1\">\u0420\u0438\u0441\u0443\u043d\u043e\u043a 1<\/cross-ref>). \u0420\u0430\u043d\u0435\u0435 \u0432 \u043a\u043e\u0433\u043e\u0440\u0442\u0435 \u0438\u0437 34 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432<cross-ref type=\"bib\" refid=\"R2\">2<\/cross-ref> \u0441 \u0432\u043f\u0435\u0440\u0432\u044b\u0435 \u0432\u043e\u0437\u043d\u0438\u043a\u0448\u0435\u0439 \u0440\u0435\u0444\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u043e\u0439 \u044d\u043f\u0438\u043b\u0435\u043f\u0441\u0438\u0435\u0439 \u0443 4 \u0438\u0437 34 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u043b\u0430\u0441\u044c \u0434\u0432\u0443\u0441\u0442\u043e\u0440\u043e\u043d\u043d\u044f\u044f \u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u044c FLAIR \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0430\u043b\u044c\u043d\u043e\u0439 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u043f\u0440\u0438 \u041c\u0420\u0422, \u043d\u0438 \u0443 \u043e\u0434\u043d\u043e\u0433\u043e \u0438\u0437 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u043d\u0435 \u0431\u044b\u043b\u043e \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u043e \u0430\u043d\u0442\u0438\u0442\u0435\u043b \u043a \u043e\u043d\u043a\u043e\u043d\u0435\u0432\u0440\u0430\u043b\u044c\u043d\u044b\u043c \u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0430\u043c. \u0423 \u0432\u0441\u0435\u0445 \u044d\u0442\u0438\u0445 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0431\u044b\u043b\u0430 \u043d\u0435\u0438\u0437\u043b\u0435\u0447\u0438\u043c\u0430\u044f \u0441 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0439 \u0442\u043e\u0447\u043a\u0438 \u0437\u0440\u0435\u043d\u0438\u044f \u044d\u043f\u0438\u043b\u0435\u043f\u0441\u0438\u044f, \u043f\u0440\u0438 \u043a\u043e\u0442\u043e\u0440\u043e\u0439 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u0430\u044f \u0432\u0438\u0437\u0443\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044f \u0432\u044b\u044f\u0432\u0438\u043b\u0430 \u0440\u0430\u0437\u0440\u0435\u0448\u0435\u043d\u0438\u0435 \u0440\u0430\u0434\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043e\u0442\u043a\u043b\u043e\u043d\u0435\u043d\u0438\u0439, \u043d\u0435\u0441\u043c\u043e\u0442\u0440\u044f \u043d\u0430 \u043f\u0440\u043e\u0434\u043e\u043b\u0436\u0430\u044e\u0449\u0438\u0435\u0441\u044f \u043f\u0440\u0438\u0441\u0442\u0443\u043f\u044b. \u0420\u0430\u043d\u0435\u0435 \u0441\u043e\u043e\u0431\u0449\u0430\u043b\u043e\u0441\u044c \u043e \u0440\u0430\u0434\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u043f\u043e\u0440\u0430\u0436\u0435\u043d\u0438\u0438 \u0431\u0438\u0438\u043d\u0441\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u043a\u043e\u0440\u044b \u043f\u0440\u0438 \u0430\u043d\u0442\u0438-NMDAR-\u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442\u0435.<cross-ref type=\"bib\" refid=\"R3\">3<\/cross-ref> \u041e\u0434\u043d\u0430\u043a\u043e \u0432 \u043d\u0430\u0448\u0435\u043c \u0441\u043b\u0443\u0447\u0430\u0435 \u043e\u0441\u0442\u0440\u043e\u0432\u043a\u043e\u0432\u044b\u0445 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0439 \u0438 \u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0443\u043c\u0430 \u043d\u0435 \u0431\u044b\u043b\u043e \u0437\u0430\u043c\u0435\u0442\u043d\u043e. \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u2026<\/p>","protected":false},"author":2,"featured_media":7458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/claustrum-hyperintensity-as-a-marker-of-anti-nmdar-encephalitis.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7457","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Claustrum hyperintensity as a marker of anti-NMDAR encephalitis - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/ru\/\u0433\u0438\u043f\u0435\u0440\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0441\u0442\u044c-\u043a\u043b\u0430\u0443\u0441\u0442\u0440\u0443\u043c\u0430-\u043a\u0430\u043a-\u043c\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Claustrum hyperintensity as a marker of anti-NMDAR encephalitis - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A young adult male patient presented with subacute onset, rapidly progressive cognitive impairment and refractory seizures and was diagnosed as definite anti N-methyl D-aspartate receptor (anti-NMDAR) antibody encephalitis as per criteria by Graus et al. (2016), following detection of culprit autoantibodies in serum.1 MRI of brain revealed bilateral T2-weighted image (T2WI)\/fluid-attenuated inversion recovery (FLAIR) claustrum hyperintensities (figure 1). Previously, in a cohort of 34 patients,2 presenting with new-onset refractory epilepsy, 4 out of 34 patients showed bilateral claustrum FLAIR hyperintensities on MRI imaging, none of whom were positive for antibodies to onconeural antigens. All these patients had medically intractable epilepsies in whom repeat imaging revealed resolution of radiological abnormalities, despite ongoing seizures. Radiological involvement of bi-insular cortex has previously been reported in context of anti-NMDAR encephalitis.3 However, in our case, no insular changes were noticeable along with claustrum hyperintensities. 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