{"id":9220,"date":"2023-12-29T08:10:06","date_gmt":"2023-12-29T05:10:06","guid":{"rendered":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/"},"modified":"2023-12-29T08:10:06","modified_gmt":"2023-12-29T05:10:06","slug":"un-approccio-alternativo-per-trattare-lobesita-gli-scienziati-sviluppano-una-capsula-ingeribile-vibrante-che-ti-fa-sentire-pieno","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/","title":{"rendered":"Un approccio alternativo per trattare l\u2019obesit\u00e0? Gli scienziati sviluppano una capsula vibrante e ingeribile che ti fa sentire pieno"},"content":{"rendered":"
<\/div>\n

I ricercatori hanno sviluppato una capsula ingeribile che, se ingerita prima di un pasto, vibra nello stomaco, inviando segnali al cervello per creare un senso illusorio di pienezza e indurlo a smettere di mangiare. La nuova capsula potrebbe emergere come un modo minimamente invasivo ed economico per trattare l\u2019obesit\u00e0.<\/p>\n

Ricercatori del Massachusetts Institute of Technology testato<\/a> la nuova capsula sugli animali e ha scoperto che, se somministrata 20 minuti prima del pasto, stimolava il rilascio di ormoni che segnalano saziet\u00e0 e riduceva l'assunzione di cibo da parte dell'animale di circa 40%. I risultati sono stati pubblicati sulla rivista Science Advances.<\/p>\n

\u201cPer chi vuole perdere peso o controllare l'appetito, potrebbe essere assunto prima di ogni pasto. Ci\u00f2 potrebbe essere davvero interessante in quanto fornirebbe un\u2019opzione in grado di ridurre al minimo gli effetti collaterali che osserviamo con gli altri trattamenti farmacologici disponibili\u201d, ha affermato l\u2019autore principale Shriya Srinivasan, dell\u2019Universit\u00e0 di Harvard, in una conferenza stampa. comunicato stampa<\/a>.<\/p>\n

Bere un bicchiere d'acqua prima di un pasto ti fa sentire meno affamato. Questo perch\u00e9 quando lo stomaco \u00e8 pieno di liquidi, i meccanorecettori del rivestimento dello stomaco inviano segnali al cervello, facendoti sentire sazio. I ricercatori hanno lavorato su questa idea e hanno testato se una capsula ingeribile che vibra all\u2019interno dello stomaco potesse allungare artificialmente i meccanorecettori e creare lo stesso senso di pienezza.<\/p>\n

\u201cQuando lo stomaco si distende, cellule specializzate chiamate meccanorecettori avvertono l\u2019allungamento e inviano segnali al cervello attraverso il nervo vago. Di conseguenza, il cervello stimola la produzione di insulina e di ormoni come il peptide C, Pyy e GLP-1. Tutti questi ormoni lavorano insieme per aiutare le persone a digerire il cibo, sentirsi sazi e smettere di mangiare. Allo stesso tempo, i livelli di grelina, un ormone che promuove la fame, diminuiscono\u201d, hanno spiegato i ricercatori.<\/p>\n

Il gruppo di ricerca ha progettato una capsula delle dimensioni di un multivitaminico, alimentata da una piccola batteria all\u2019ossido d\u2019argento. Dopo aver ingerito la capsula, i fluidi gastrici sciolgono la membrana che la ricopre, completano il circuito elettronico e attivano il motore vibrante.<\/p>\n

Durante gli esperimenti sugli animali, i ricercatori hanno notato che quando il dispositivo vibrava, i livelli ormonali imitavano da vicino gli schemi osservati dopo un pasto regolare. Non sono stati riscontrati segni di ostruzione, perforazione o altri effetti negativi negli animali mentre la pillola era nel tratto digestivo. Le pillole attraversavano il tratto digestivo entro quattro o cinque giorni.<\/p>\n

L'attuale versione della pillola pu\u00f2 vibrare per circa 30 minuti dopo aver raggiunto lo stomaco. I ricercatori prevedono di estenderlo per periodi pi\u00f9 lunghi e di testare la possibilit\u00e0 di attivarlo e disattivarlo in modalit\u00e0 wireless.<\/p>\n

I ricercatori sperano che la nuova pillola possa funzionare come un\u2019alternativa pi\u00f9 sicura agli attuali metodi di trattamento dell\u2019obesit\u00e0 quando la dieta e l\u2019esercizio fisico falliscono. Molti interventi medici esistenti, come l\u2019intervento di bypass gastrico e i palloncini gastrici, sono spesso considerati invasivi e non sono ampiamente raccomandati a causa di problemi di sicurezza. Sebbene farmaci come gli agonisti del GLP-1 possano aiutare nella perdita di peso, molti di essi richiedono l\u2019iniezione, il che li rende meno convenienti e inaccessibili per molti.<\/p>\n

\u201cPer molte popolazioni, alcune delle terapie pi\u00f9 efficaci contro l\u2019obesit\u00e0 sono molto costose. Su larga scala, il nostro dispositivo potrebbe essere prodotto a un prezzo piuttosto conveniente. Mi piacerebbe vedere come questo trasformerebbe l\u2019assistenza e la terapia per le persone in contesti sanitari globali che potrebbero non avere accesso ad alcune delle opzioni pi\u00f9 sofisticate o costose oggi disponibili\u201d, ha affermato Srinivasan.<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

I ricercatori hanno sviluppato una capsula ingeribile che, se ingerita prima di un pasto, vibra nello stomaco, inviando segnali al cervello per creare un senso illusorio di pienezza e indurlo a smettere di mangiare. La nuova capsula potrebbe emergere come un modo minimamente invasivo ed economico per trattare l\u2019obesit\u00e0.<\/p>\n

Ricercatori del Massachusetts Institute of Technology testato<\/a> la nuova capsula sugli animali e ha scoperto che, se somministrata 20 minuti prima del pasto, stimolava il rilascio di ormoni che segnalano saziet\u00e0 e riduceva l'assunzione di cibo da parte dell'animale di circa 40%. I risultati sono stati pubblicati sulla rivista Science Advances.<\/p>\n

\u201cPer chi vuole perdere peso o controllare l'appetito, potrebbe essere assunto prima di ogni pasto. Ci\u00f2 potrebbe essere davvero interessante in quanto fornirebbe un\u2019opzione in grado di ridurre al minimo gli effetti collaterali che osserviamo con gli altri trattamenti farmacologici disponibili\u201d, ha affermato l\u2019autore principale Shriya Srinivasan, dell\u2019Universit\u00e0 di Harvard, in una conferenza stampa. comunicato stampa<\/a>.<\/p>\n

Bere un bicchiere d'acqua prima di un pasto ti fa sentire meno affamato. Questo perch\u00e9 quando lo stomaco \u00e8 pieno di liquidi, i meccanorecettori del rivestimento dello stomaco inviano segnali al cervello, facendoti sentire sazio. I ricercatori hanno lavorato su questa idea e hanno testato se una capsula ingeribile che vibra all\u2019interno dello stomaco potesse allungare artificialmente i meccanorecettori e creare lo stesso senso di pienezza.<\/p>\n

\u201cQuando lo stomaco si distende, cellule specializzate chiamate meccanorecettori avvertono l\u2019allungamento e inviano segnali al cervello attraverso il nervo vago. Di conseguenza, il cervello stimola la produzione di insulina e di ormoni come il peptide C, Pyy e GLP-1. Tutti questi ormoni lavorano insieme per aiutare le persone a digerire il cibo, sentirsi sazi e smettere di mangiare. Allo stesso tempo, i livelli di grelina, un ormone che promuove la fame, diminuiscono\u201d, hanno spiegato i ricercatori.<\/p>\n

Il gruppo di ricerca ha progettato una capsula delle dimensioni di un multivitaminico, alimentata da una piccola batteria all\u2019ossido d\u2019argento. Dopo aver ingerito la capsula, i fluidi gastrici sciolgono la membrana che la ricopre, completano il circuito elettronico e attivano il motore vibrante.<\/p>\n

Durante gli esperimenti sugli animali, i ricercatori hanno notato che quando il dispositivo vibrava, i livelli ormonali imitavano da vicino gli schemi osservati dopo un pasto regolare. Non sono stati riscontrati segni di ostruzione, perforazione o altri effetti negativi negli animali mentre la pillola era nel tratto digestivo. Le pillole attraversavano il tratto digestivo entro quattro o cinque giorni.<\/p>\n

L'attuale versione della pillola pu\u00f2 vibrare per circa 30 minuti dopo aver raggiunto lo stomaco. I ricercatori prevedono di estenderlo per periodi pi\u00f9 lunghi e di testare la possibilit\u00e0 di attivarlo e disattivarlo in modalit\u00e0 wireless.<\/p>\n

I ricercatori sperano che la nuova pillola possa funzionare come un\u2019alternativa pi\u00f9 sicura agli attuali metodi di trattamento dell\u2019obesit\u00e0 quando la dieta e l\u2019esercizio fisico falliscono. Molti interventi medici esistenti, come l\u2019intervento di bypass gastrico e i palloncini gastrici, sono spesso considerati invasivi e non sono ampiamente raccomandati a causa di problemi di sicurezza. Sebbene farmaci come gli agonisti del GLP-1 possano aiutare nella perdita di peso, molti di essi richiedono l\u2019iniezione, il che li rende meno convenienti e inaccessibili per molti.<\/p>\n

\u201cPer molte popolazioni, alcune delle terapie pi\u00f9 efficaci contro l\u2019obesit\u00e0 sono molto costose. Su larga scala, il nostro dispositivo potrebbe essere prodotto a un prezzo piuttosto conveniente. Mi piacerebbe vedere come questo trasformerebbe l\u2019assistenza e la terapia per le persone in contesti sanitari globali che potrebbero non avere accesso ad alcune delle opzioni pi\u00f9 sofisticate o costose oggi disponibili\u201d, ha affermato Srinivasan.<\/p>","protected":false},"author":2,"featured_media":9221,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9220","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nAn Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/un-approccio-alternativo-per-trattare-lobesita-gli-scienziati-sviluppano-una-capsula-ingeribile-vibrante-che-ti-fa-sentire-pieno\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Researchers have developed an ingestible capsule, which when ingested before a meal, vibrates in the stomach, sending signals to the brain to create an illusory sense of fullness and trick it to stop eating. The new capsule could emerge as a minimally invasive and cost-effective way to treat obesity.Researchers from the Massachusetts Institute of Technology tested the new capsule on animals and found that when given 20 minutes before eating, it stimulated the release of hormones that signal satiety and reduced the animal's food intake by about 40%. The results were published in the journal Science Advances."For somebody who wants to lose weight or control their appetite, it could be taken before each meal. This could be really interesting in that it would provide an option that could minimize the side effects that we see with the other pharmacological treatments out there," lead author Shriya Srinivasan, from Harvard University, said in a news release.Drinking a glass of water before a meal makes you feel less hungry. This is because when the stomach is full of liquid, the mechanoreceptors of the stomach lining send signals to the brain, making you feel satiated. Researchers worked on this idea and tested if an ingestible capsule that vibrates within the stomach could artificially stretch the mechanoreceptors and create the same sense of fullness."When the stomach becomes distended, specialized cells called mechanoreceptors sense that stretching and send signals to the brain via the vagus nerve. As a result, the brain stimulates the production of insulin, as well as hormones such as C-peptide, Pyy and GLP-1. All of these hormones work together to help people digest their food, feel full, and stop eating. At the same time, levels of ghrelin, a hunger-promoting hormone, go down," researchers explained.The research team designed a capsule about the size of a multivitamin, powered by a small silver oxide battery. After the capsule gets ingested, the gastric fluids dissolve the membrane that covers it, complete the electronic circuit and activate the vibrating motor.During animal trials, researchers noticed that when the device was vibrating, hormone levels closely mimicked the patterns seen after a regular meal. There were no signs of obstruction, perforation or other negative impacts in animals while the pill was in their digestive tract. The pills passed through the digestive tract within four or five days.The current version of the pill can vibrate for about 30 minutes after reaching the stomach. Researchers plan to extend it for longer periods and test the possibility of activating and deactivating it wirelessly.Researchers hope the new pill could work as a safer alternative to the current methods of treating obesity when diet and exercise fail. Many existing medical interventions such as gastric bypass surgery and gastric balloons are often considered invasive and are not widely recommended due to safety concerns. While drugs like GLP-1 agonists can help in weight loss, many of them require injection, making them less convenient and unaffordable for many."For a lot of populations, some of the more effective therapies for obesity are very costly. At scale, our device could be manufactured at a pretty cost-effective price point. I'd love to see how this would transform care and therapy for people in global health settings who may not have access to some of the more sophisticated or expensive options that are available today," Srinivasan said.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/un-approccio-alternativo-per-trattare-lobesita-gli-scienziati-sviluppano-una-capsula-ingeribile-vibrante-che-ti-fa-sentire-pieno\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-29T05:10:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"An Alternative Approach To Treat Obesity? 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Gli scienziati sviluppano una capsula vibrante e ingeribile che ti fa sentire sazio - Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/it\/un-approccio-alternativo-per-trattare-lobesita-gli-scienziati-sviluppano-una-capsula-ingeribile-vibrante-che-ti-fa-sentire-pieno\/","og_locale":"it_IT","og_type":"article","og_title":"An Alternative Approach To Treat Obesity? Scientists Develop Vibrating, Ingestible Capsule That Makes You Feel Full - Urban Care Clinic","og_description":"Researchers have developed an ingestible capsule, which when ingested before a meal, vibrates in the stomach, sending signals to the brain to create an illusory sense of fullness and trick it to stop eating. The new capsule could emerge as a minimally invasive and cost-effective way to treat obesity.Researchers from the Massachusetts Institute of Technology tested the new capsule on animals and found that when given 20 minutes before eating, it stimulated the release of hormones that signal satiety and reduced the animal's food intake by about 40%. The results were published in the journal Science Advances.\"For somebody who wants to lose weight or control their appetite, it could be taken before each meal. This could be really interesting in that it would provide an option that could minimize the side effects that we see with the other pharmacological treatments out there,\" lead author Shriya Srinivasan, from Harvard University, said in a news release.Drinking a glass of water before a meal makes you feel less hungry. This is because when the stomach is full of liquid, the mechanoreceptors of the stomach lining send signals to the brain, making you feel satiated. Researchers worked on this idea and tested if an ingestible capsule that vibrates within the stomach could artificially stretch the mechanoreceptors and create the same sense of fullness.\"When the stomach becomes distended, specialized cells called mechanoreceptors sense that stretching and send signals to the brain via the vagus nerve. As a result, the brain stimulates the production of insulin, as well as hormones such as C-peptide, Pyy and GLP-1. All of these hormones work together to help people digest their food, feel full, and stop eating. At the same time, levels of ghrelin, a hunger-promoting hormone, go down,\" researchers explained.The research team designed a capsule about the size of a multivitamin, powered by a small silver oxide battery. After the capsule gets ingested, the gastric fluids dissolve the membrane that covers it, complete the electronic circuit and activate the vibrating motor.During animal trials, researchers noticed that when the device was vibrating, hormone levels closely mimicked the patterns seen after a regular meal. There were no signs of obstruction, perforation or other negative impacts in animals while the pill was in their digestive tract. The pills passed through the digestive tract within four or five days.The current version of the pill can vibrate for about 30 minutes after reaching the stomach. Researchers plan to extend it for longer periods and test the possibility of activating and deactivating it wirelessly.Researchers hope the new pill could work as a safer alternative to the current methods of treating obesity when diet and exercise fail. Many existing medical interventions such as gastric bypass surgery and gastric balloons are often considered invasive and are not widely recommended due to safety concerns. While drugs like GLP-1 agonists can help in weight loss, many of them require injection, making them less convenient and unaffordable for many.\"For a lot of populations, some of the more effective therapies for obesity are very costly. At scale, our device could be manufactured at a pretty cost-effective price point. I'd love to see how this would transform care and therapy for people in global health settings who may not have access to some of the more sophisticated or expensive options that are available today,\" Srinivasan said.","og_url":"https:\/\/urbancare.clinic\/it\/un-approccio-alternativo-per-trattare-lobesita-gli-scienziati-sviluppano-una-capsula-ingeribile-vibrante-che-ti-fa-sentire-pieno\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-12-29T05:10:06+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2024\/01\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Scritto da":"Urban Care Clinic","Tempo di lettura stimato":"3 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/an-alternative-approach-to-treat-obesity-scientists-develop-vibrating-ingestible-capsule-that-makes-you-feel-full\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"An Alternative Approach To Treat Obesity? 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