{"id":9151,"date":"2023-12-07T11:54:53","date_gmt":"2023-12-07T08:54:53","guid":{"rendered":"https:\/\/urbancare.simplyit.solutions\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"modified":"2023-12-07T11:54:53","modified_gmt":"2023-12-07T08:54:53","slug":"le-persone-sopra-i-50-anni-potrebbero-avere-un-invecchiamento-accelerato-in-almeno-1-organo-che-un-esame-del-sangue-potrebbe-rilevare","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/","title":{"rendered":"Le persone sopra i 50 anni potrebbero aver accelerato l'invecchiamento in almeno 1 organo; Un esame del sangue potrebbe rilevarlo"},"content":{"rendered":"
<\/div>\n

Ogni organo del nostro corpo invecchia a un ritmo diverso. I ricercatori ora affermano che circa 18% di adulti sani di et\u00e0 superiore ai 50 anni vanno incontro a un invecchiamento accelerato in almeno uno dei loro organi.<\/p>\n

UN studio<\/a>, guidato da ricercatori della Stanford Medicine, suggerisce che con un semplice esame del sangue, potrebbe essere possibile rilevare l'invecchiamento accelerato di un organo che aumenta il rischio di malattie e mortalit\u00e0.<\/p>\n

\u201cPossiamo stimare l\u2019et\u00e0 biologica di un organo in una persona apparentemente sana. Ci\u00f2, a sua volta, predice il rischio di una persona di malattie legate a quell\u2019organo\u201d, disse<\/a> l'autore senior dello studio, Tony Wyss-Coray.<\/p>\n

"Numerosi studi hanno prodotto singoli numeri che rappresentano l'et\u00e0 biologica degli individui - l'et\u00e0 implicata da una sofisticata serie di biomarcatori - in contrapposizione alla loro et\u00e0 cronica, il numero effettivo di anni trascorsi dalla loro nascita", ha detto Wyss-Coray.<\/p>\n

Tuttavia, il team ha fatto un ulteriore passo avanti identificando l\u2019et\u00e0 biologica di ciascuno degli 11 organi e sistemi di organi chiave: cuore, grasso, polmone, sistema immunitario, rene, fegato, muscoli, pancreas, cervello, sistema vascolare e intestino.<\/p>\n

"Quando abbiamo confrontato l'et\u00e0 biologica di ciascuno di questi organi per ciascun individuo con le sue controparti in un ampio gruppo di persone senza malattie gravi evidenti, abbiamo scoperto che 18.4% di quelli di et\u00e0 pari o superiore a 50 anni aveva almeno un organo che invecchiava significativamente pi\u00f9 rapidamente dell'altro. nella media\u201d, ha detto Wyss-Coray.<\/p>\n

Lo studio ha valutato 5.678 partecipanti. I risultati hanno mostrato che solo 1 su 60 partecipanti aveva due organi che invecchiavano a un ritmo accelerato. L\u2019invecchiamento accelerato di due organi aumenta il rischio di mortalit\u00e0 di 6,5 volte.<\/p>\n

\u201cUtilizzando tecnologie disponibili in commercio e un algoritmo di loro progettazione, i ricercatori hanno valutato i livelli di migliaia di proteine nel sangue delle persone, hanno determinato che quasi 1.000 di quelle proteine hanno avuto origine all\u2019interno di uno o di un altro singolo organo e hanno collegato i livelli aberranti di quelle proteine ai corrispondenti invecchiamento accelerato degli organi e suscettibilit\u00e0 alle malattie e alla mortalit\u00e0\u201d, hanno spiegato i ricercatori.<\/p>\n

Il gruppo di ricerca ha stimato un \u201cdivario di et\u00e0\u201d per ciascun organo. Il divario di et\u00e0 si riferisce alla differenza tra l'et\u00e0 effettiva di un organo e l'et\u00e0 stimata in base ai calcoli basati sulle proteine organo-specifiche dell'algoritmo. Le differenze di et\u00e0 identificate, ad eccezione di quella intestinale, erano significativamente associate al rischio futuro di morte per tutte le cause.<\/p>\n

Avere un organo con invecchiamento accelerato aumenta il rischio di mortalit\u00e0 da 15% a 50% nei prossimi 15 anni, hanno detto i ricercatori. Il rischio di mortalit\u00e0 dipende dall\u2019organo colpito.<\/p>\n

Mentre l\u2019invecchiamento accelerato del cuore aumenta il rischio di insufficienza cardiaca di 2,5 volte, l\u2019invecchiamento cerebrale aumenta il rischio di declino cognitivo di 1,8 volte.<\/p>\n

I ricercatori affermano che, se verificato in una popolazione pi\u00f9 ampia, potrebbe aiutare a prevedere l\u2019insufficienza d\u2019organo e il rischio di malattia anche prima che compaiano i sintomi.<\/p>\n

\u201cSe riusciamo a riprodurre questa scoperta in 50.000 o 100.000 individui, significher\u00e0 che monitorando la salute dei singoli organi in persone apparentemente sane, potremmo essere in grado di trovare organi che stanno subendo un invecchiamento accelerato nei corpi delle persone, e potremmo essere in grado di per curare le persone prima che si ammalino\u201d, ha detto Wyss-Coray.<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Ogni organo del nostro corpo invecchia a un ritmo diverso. I ricercatori ora affermano che circa 18% di adulti sani di et\u00e0 superiore ai 50 anni vanno incontro a un invecchiamento accelerato in almeno uno dei loro organi.<\/p>\n

UN studio<\/a>, guidato da ricercatori della Stanford Medicine, suggerisce che con un semplice esame del sangue, potrebbe essere possibile rilevare l'invecchiamento accelerato di un organo che aumenta il rischio di malattie e mortalit\u00e0.<\/p>\n

\u201cPossiamo stimare l\u2019et\u00e0 biologica di un organo in una persona apparentemente sana. Ci\u00f2, a sua volta, predice il rischio di una persona di malattie legate a quell\u2019organo\u201d, disse<\/a> l'autore senior dello studio, Tony Wyss-Coray.<\/p>\n

"Numerosi studi hanno prodotto singoli numeri che rappresentano l'et\u00e0 biologica degli individui - l'et\u00e0 implicata da una sofisticata serie di biomarcatori - in contrapposizione alla loro et\u00e0 cronica, il numero effettivo di anni trascorsi dalla loro nascita", ha detto Wyss-Coray.<\/p>\n

Tuttavia, il team ha fatto un ulteriore passo avanti identificando l\u2019et\u00e0 biologica di ciascuno degli 11 organi e sistemi di organi chiave: cuore, grasso, polmone, sistema immunitario, rene, fegato, muscoli, pancreas, cervello, sistema vascolare e intestino.<\/p>\n

"Quando abbiamo confrontato l'et\u00e0 biologica di ciascuno di questi organi per ciascun individuo con le sue controparti in un ampio gruppo di persone senza malattie gravi evidenti, abbiamo scoperto che 18.4% di quelli di et\u00e0 pari o superiore a 50 anni aveva almeno un organo che invecchiava significativamente pi\u00f9 rapidamente dell'altro. nella media\u201d, ha detto Wyss-Coray.<\/p>\n

Lo studio ha valutato 5.678 partecipanti. I risultati hanno mostrato che solo 1 su 60 partecipanti aveva due organi che invecchiavano a un ritmo accelerato. L\u2019invecchiamento accelerato di due organi aumenta il rischio di mortalit\u00e0 di 6,5 volte.<\/p>\n

\u201cUtilizzando tecnologie disponibili in commercio e un algoritmo di loro progettazione, i ricercatori hanno valutato i livelli di migliaia di proteine nel sangue delle persone, hanno determinato che quasi 1.000 di quelle proteine hanno avuto origine all\u2019interno di uno o di un altro singolo organo e hanno collegato i livelli aberranti di quelle proteine ai corrispondenti invecchiamento accelerato degli organi e suscettibilit\u00e0 alle malattie e alla mortalit\u00e0\u201d, hanno spiegato i ricercatori.<\/p>\n

Il gruppo di ricerca ha stimato un \u201cdivario di et\u00e0\u201d per ciascun organo. Il divario di et\u00e0 si riferisce alla differenza tra l'et\u00e0 effettiva di un organo e l'et\u00e0 stimata in base ai calcoli basati sulle proteine organo-specifiche dell'algoritmo. Le differenze di et\u00e0 identificate, ad eccezione di quella intestinale, erano significativamente associate al rischio futuro di morte per tutte le cause.<\/p>\n

Avere un organo con invecchiamento accelerato aumenta il rischio di mortalit\u00e0 da 15% a 50% nei prossimi 15 anni, hanno detto i ricercatori. Il rischio di mortalit\u00e0 dipende dall\u2019organo colpito.<\/p>\n

Mentre l\u2019invecchiamento accelerato del cuore aumenta il rischio di insufficienza cardiaca di 2,5 volte, l\u2019invecchiamento cerebrale aumenta il rischio di declino cognitivo di 1,8 volte.<\/p>\n

I ricercatori affermano che, se verificato in una popolazione pi\u00f9 ampia, potrebbe aiutare a prevedere l\u2019insufficienza d\u2019organo e il rischio di malattia anche prima che compaiano i sintomi.<\/p>\n

\u201cSe riusciamo a riprodurre questa scoperta in 50.000 o 100.000 individui, significher\u00e0 che monitorando la salute dei singoli organi in persone apparentemente sane, potremmo essere in grado di trovare organi che stanno subendo un invecchiamento accelerato nei corpi delle persone, e potremmo essere in grado di per curare le persone prima che si ammalino\u201d, ha detto Wyss-Coray.<\/p>","protected":false},"author":2,"featured_media":9152,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9151","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nPeople Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/le-persone-sopra-i-50-anni-potrebbero-avere-un-invecchiamento-accelerato-in-almeno-1-organo-che-un-esame-del-sangue-potrebbe-rilevare\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality."We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person's risk for disease related to that organ," said the study's senior author, Tony Wyss-Coray."Numerous studies have come up with single numbers representing individuals' biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth," Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine."When we compared each of these organs' biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average," Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times."Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people's blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs' accelerated aging and susceptibility to disease and mortality," the researchers explained.The research team estimated an "age gap" for each organ. Age gap refers to the difference between an organ's actual age and the age estimated based on the algorithm's organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear."If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people's bodies, and we might be able to treat people before they get sick," Wyss-Coray said.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/le-persone-sopra-i-50-anni-potrebbero-avere-un-invecchiamento-accelerato-in-almeno-1-organo-che-un-esame-del-sangue-potrebbe-rilevare\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-07T08:54:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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Un esame del sangue potrebbe rilevarlo - Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/it\/le-persone-sopra-i-50-anni-potrebbero-avere-un-invecchiamento-accelerato-in-almeno-1-organo-che-un-esame-del-sangue-potrebbe-rilevare\/","og_locale":"it_IT","og_type":"article","og_title":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic","og_description":"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality.\"We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person's risk for disease related to that organ,\" said the study's senior author, Tony Wyss-Coray.\"Numerous studies have come up with single numbers representing individuals' biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth,\" Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine.\"When we compared each of these organs' biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average,\" Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times.\"Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people's blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs' accelerated aging and susceptibility to disease and mortality,\" the researchers explained.The research team estimated an \"age gap\" for each organ. Age gap refers to the difference between an organ's actual age and the age estimated based on the algorithm's organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear.\"If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people's bodies, and we might be able to treat people before they get sick,\" Wyss-Coray said.","og_url":"https:\/\/urbancare.clinic\/it\/le-persone-sopra-i-50-anni-potrebbero-avere-un-invecchiamento-accelerato-in-almeno-1-organo-che-un-esame-del-sangue-potrebbe-rilevare\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-12-07T08:54:53+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Scritto da":"Urban Care Clinic","Tempo di lettura stimato":"2 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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