{"id":8478,"date":"2023-07-07T10:25:41","date_gmt":"2023-07-07T07:25:41","guid":{"rendered":"https:\/\/urbancare.clinic\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth\/"},"modified":"2023-07-07T10:25:41","modified_gmt":"2023-07-07T07:25:41","slug":"farmaci-per-far-ricrescere-i-denti-inizieranno-gli-studi-per-farmaci-che-possono-aiutare-nella-ricrescita","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/farmaci-per-far-ricrescere-i-denti-inizieranno-gli-studi-per-farmaci-che-possono-aiutare-nella-ricrescita\/","title":{"rendered":"Farmaco per far ricrescere i denti? Prove avviate per la medicina che pu\u00f2 aiutare nella ricrescita"},"content":{"rendered":"
<\/div>\n

Sembra che una buona notizia sia proprio dietro l'angolo per le persone senza denti, poich\u00e9 \u00e8 in lavorazione un farmaco miracoloso per la ricrescita dei denti.<\/p>\n

Se le sperimentazioni cliniche andranno bene, entro il 2030 sar\u00e0 disponibile il primo farmaco che permette alle persone di far crescere una nuova dentatura.<\/p>\n

Il team di ricerca giapponese, che \u00e8 alla base dell'innovativa invenzione, inizier\u00e0 le prove nel luglio 2024, secondo il New York Post segnalato<\/a>.<\/p>\n

Il nuovo farmaco potrebbe aiutare a trattare le persone che non hanno una dentatura completa a causa di condizioni genetiche come l'agenesia dei denti. Dente agenesia<\/a> \u00e8 una condizione in cui una persona nasce senza alcuni denti. La condizione colpisce tra 3% e 10% della popolazione statunitense.<\/p>\n

Esistono tre tipi di agenesia dentale: anodontia, ipodontia e oligodonzia. Le persone con anodontia non sviluppano nessuno dei loro denti naturali. Quando a un paziente mancano sei o pi\u00f9 denti, la condizione \u00e8 classificata come oligodonzia e quando mancano da uno a sei denti, si parla di ipodontia. I pazienti con agenesia avranno difficolt\u00e0 a masticare, deglutire e parlare fin dalla giovane et\u00e0, il che pu\u00f2 persino influire sul loro sviluppo. L'attuale trattamento include l'uso di dentiere e impianti dentali.<\/p>\n

\u201cL'idea di far crescere nuovi denti \u00e8 il sogno di ogni dentista. Ci lavoro da quando ero uno studente laureato. Ero fiducioso che sarei stato in grado di realizzarlo ", ha detto Katsu Takahashi, ricercatore capo e capo del dipartimento di odontoiatria e chirurgia orale presso l'Istituto di ricerca medica Kitano Hospital in Giappone, al sito di notizie quotidiane nazionali Il Mainichi<\/a>.<\/p>\n

Ricerche precedenti hanno scoperto che alcuni geni, una volta eliminati, farebbero crescere meno denti nei topi geneticamente modificati.<\/p>\n

\u201cIl numero di denti variava a causa della mutazione di un solo gene. Se facciamo di questo l'obiettivo della nostra ricerca, dovrebbe esserci un modo per cambiare il numero di denti (le persone ne hanno)", ha spiegato Takahashi come ha avviato lo studio.<\/p>\n

I ricercatori hanno poi scoperto che USAG-1, una proteina sintetizzata dal gene, limitava la crescita di denti<\/a> e bloccando la proteina crescerebbero pi\u00f9 denti. Il team ha quindi sviluppato un farmaco anticorpale neutralizzante che potrebbe bloccare la funzione della proteina.<\/p>\n

In uno studio condotto nel 2018, il team di Takahashi ha testato con successo l'efficacia del medicinale nei topi con un numero di denti congenitamente basso.<\/p>\n

Takahashi spera che il nuovo farmaco, dopo i necessari studi clinici, fornisca un'opzione in pi\u00f9 alle persone che non hanno una dentatura completa.<\/p>\n

"In ogni caso, speriamo di vedere un momento in cui la medicina per la ricrescita dei denti sar\u00e0 una terza scelta accanto a protesi e impianti", ha affermato.<\/p>\n

Dopo ulteriori test, i ricercatori sperano che il farmaco possa essere utilizzato anche in futuro per trattare i segni di anodontia nei bambini dai 2 ai 6 anni. "Speriamo di aprire la strada all'uso clinico del medicinale", ha aggiunto.<\/p>\n

Pubblicato da Medicaldaily.com<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Sembra che una buona notizia sia proprio dietro l'angolo per le persone senza denti, poich\u00e9 \u00e8 in lavorazione un farmaco miracoloso per la ricrescita dei denti.<\/p>\n

Se le sperimentazioni cliniche andranno bene, entro il 2030 sar\u00e0 disponibile il primo farmaco che permette alle persone di far crescere una nuova dentatura.<\/p>\n

Il team di ricerca giapponese, che \u00e8 alla base dell'innovativa invenzione, inizier\u00e0 le prove nel luglio 2024, secondo il New York Post segnalato<\/a>.<\/p>\n

Il nuovo farmaco potrebbe aiutare a trattare le persone che non hanno una dentatura completa a causa di condizioni genetiche come l'agenesia dei denti. Dente agenesia<\/a> \u00e8 una condizione in cui una persona nasce senza alcuni denti. La condizione colpisce tra 3% e 10% della popolazione statunitense.<\/p>\n

Esistono tre tipi di agenesia dentale: anodontia, ipodontia e oligodonzia. Le persone con anodontia non sviluppano nessuno dei loro denti naturali. Quando a un paziente mancano sei o pi\u00f9 denti, la condizione \u00e8 classificata come oligodonzia e quando mancano da uno a sei denti, si parla di ipodontia. I pazienti con agenesia avranno difficolt\u00e0 a masticare, deglutire e parlare fin dalla giovane et\u00e0, il che pu\u00f2 persino influire sul loro sviluppo. L'attuale trattamento include l'uso di dentiere e impianti dentali.<\/p>\n

\u201cL'idea di far crescere nuovi denti \u00e8 il sogno di ogni dentista. Ci lavoro da quando ero uno studente laureato. Ero fiducioso che sarei stato in grado di realizzarlo ", ha detto Katsu Takahashi, ricercatore capo e capo del dipartimento di odontoiatria e chirurgia orale presso l'Istituto di ricerca medica Kitano Hospital in Giappone, al sito di notizie quotidiane nazionali Il Mainichi<\/a>.<\/p>\n

Ricerche precedenti hanno scoperto che alcuni geni, una volta eliminati, farebbero crescere meno denti nei topi geneticamente modificati.<\/p>\n

\u201cIl numero di denti variava a causa della mutazione di un solo gene. Se facciamo di questo l'obiettivo della nostra ricerca, dovrebbe esserci un modo per cambiare il numero di denti (le persone ne hanno)", ha spiegato Takahashi come ha avviato lo studio.<\/p>\n

I ricercatori hanno poi scoperto che USAG-1, una proteina sintetizzata dal gene, limitava la crescita di denti<\/a> e bloccando la proteina crescerebbero pi\u00f9 denti. Il team ha quindi sviluppato un farmaco anticorpale neutralizzante che potrebbe bloccare la funzione della proteina.<\/p>\n

In uno studio condotto nel 2018, il team di Takahashi ha testato con successo l'efficacia del medicinale nei topi con un numero di denti congenitamente basso.<\/p>\n

Takahashi spera che il nuovo farmaco, dopo i necessari studi clinici, fornisca un'opzione in pi\u00f9 alle persone che non hanno una dentatura completa.<\/p>\n

"In ogni caso, speriamo di vedere un momento in cui la medicina per la ricrescita dei denti sar\u00e0 una terza scelta accanto a protesi e impianti", ha affermato.<\/p>\n

Dopo ulteriori test, i ricercatori sperano che il farmaco possa essere utilizzato anche in futuro per trattare i segni di anodontia nei bambini dai 2 ai 6 anni. "Speriamo di aprire la strada all'uso clinico del medicinale", ha aggiunto.<\/p>\n

Pubblicato da Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8479,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8478","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nDrug To Regrow Teeth? Trials Set To Start For Medicine That May Help In Regrowth - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/farmaci-per-far-ricrescere-i-denti-inizieranno-gli-studi-per-farmaci-che-possono-aiutare-nella-ricrescita\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Drug To Regrow Teeth? Trials Set To Start For Medicine That May Help In Regrowth - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"It looks like good news is just around the corner for people without teeth, as a miracle drug is in the works for tooth regrowth.If the clinical trials go well, the first medicine that allows people to grow a new set of teeth would be available by 2030.The Japanese research team, which is behind the groundbreaking invention, is set to begin the trials in July 2024, the New York Post reported.The new drug could help in treating people who do not have a full set of teeth due to genetic conditions such as tooth agenesis. Tooth agenesis is a condition in which a person is born without some of their teeth. The condition affects between 3% and 10% of the U.S. population.There are three types of dental agenesis: anodontia, hypodontia, and oligodontia. People with anodontia do not develop any of their natural teeth. When a patient lacks six or more teeth, the condition is categorized as oligodontia and when one to six teeth are absent, it is called hypodontia. Patients with agenesis will have difficulty chewing, swallowing, and speaking from a young age, which can even impact their development. The current treatment includes the use of dentures and dental implants."The idea of growing new teeth is every dentist's dream. I've been working on this since I was a graduate student. I was confident I'd be able to make it happen," Katsu Takahashi, lead researcher and head of the dentistry and oral surgery department at the Medical Research Institute Kitano Hospital in Japan, told the national daily news site The Mainichi.Earlier research has found that certain genes, when deleted, would cause genetically modified mice to grow fewer teeth."The number of teeth varied through the mutation of just one gene. If we make that the target of our research, there should be a way to change the number of teeth (people have)," Takahashi explained how he initiated the study.The researchers then found that USAG-1, a protein synthesized by the gene restricted the growth of teeth and by blocking the protein more teeth would grow. The team then developed a neutralizing antibody medicine that could block the protein's function.In a study conducted in 2018, Takahashi's team successfully tested the efficiency of the medicine in mice with a congenitally low number of teeth.Takahashi hopes the new drug after necessary clinical trials will provide one more option to the people who do not have a full set of teeth."In any case, we're hoping to see a time when tooth-regrowth medicine is a third choice alongside dentures and implants," he said.After further tests, the researchers hope the drug could also be used in the future to treat signs of anodontia in kids from ages 2 to 6. "We hope to pave the way for the medicine's clinical use," he added.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/farmaci-per-far-ricrescere-i-denti-inizieranno-gli-studi-per-farmaci-che-possono-aiutare-nella-ricrescita\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-07T07:25:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Drug To Regrow Teeth? 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Trials Set To Start For Medicine That May Help In Regrowth - Urban Care Clinic","og_description":"It looks like good news is just around the corner for people without teeth, as a miracle drug is in the works for tooth regrowth.If the clinical trials go well, the first medicine that allows people to grow a new set of teeth would be available by 2030.The Japanese research team, which is behind the groundbreaking invention, is set to begin the trials in July 2024, the New York Post reported.The new drug could help in treating people who do not have a full set of teeth due to genetic conditions such as tooth agenesis. Tooth agenesis is a condition in which a person is born without some of their teeth. The condition affects between 3% and 10% of the U.S. population.There are three types of dental agenesis: anodontia, hypodontia, and oligodontia. People with anodontia do not develop any of their natural teeth. When a patient lacks six or more teeth, the condition is categorized as oligodontia and when one to six teeth are absent, it is called hypodontia. Patients with agenesis will have difficulty chewing, swallowing, and speaking from a young age, which can even impact their development. The current treatment includes the use of dentures and dental implants.\"The idea of growing new teeth is every dentist's dream. I've been working on this since I was a graduate student. I was confident I'd be able to make it happen,\" Katsu Takahashi, lead researcher and head of the dentistry and oral surgery department at the Medical Research Institute Kitano Hospital in Japan, told the national daily news site The Mainichi.Earlier research has found that certain genes, when deleted, would cause genetically modified mice to grow fewer teeth.\"The number of teeth varied through the mutation of just one gene. 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The team then developed a neutralizing antibody medicine that could block the protein's function.In a study conducted in 2018, Takahashi's team successfully tested the efficiency of the medicine in mice with a congenitally low number of teeth.Takahashi hopes the new drug after necessary clinical trials will provide one more option to the people who do not have a full set of teeth.\"In any case, we're hoping to see a time when tooth-regrowth medicine is a third choice alongside dentures and implants,\" he said.After further tests, the researchers hope the drug could also be used in the future to treat signs of anodontia in kids from ages 2 to 6. \"We hope to pave the way for the medicine's clinical use,\" he added.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/it\/farmaci-per-far-ricrescere-i-denti-inizieranno-gli-studi-per-farmaci-che-possono-aiutare-nella-ricrescita\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-07-07T07:25:41+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth.jpg","type":"","width":"","height":""}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_image":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth.jpg","twitter_misc":{"Scritto da":"Urban Care Clinic","Tempo di lettura stimato":"2 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/drug-to-regrow-teeth-trials-set-to-start-for-medicine-that-may-help-in-regrowth\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c"},"headline":"Drug To Regrow Teeth? 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