{"id":8303,"date":"2023-06-06T09:32:34","date_gmt":"2023-06-06T06:32:34","guid":{"rendered":"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/"},"modified":"2023-06-06T09:32:34","modified_gmt":"2023-06-06T06:32:34","slug":"uno-studio-sulla-terapia-ormonale-sostitutiva-afferma-che-lassunzione-di-estrogeni-per-via-orale-aumenta-il-rischio-di-ipertensione","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/uno-studio-sulla-terapia-ormonale-sostitutiva-afferma-che-lassunzione-di-estrogeni-per-via-orale-aumenta-il-rischio-di-ipertensione\/","title":{"rendered":"Terapia ormonale sostitutiva: uno studio afferma che l&#039;assunzione orale di estrogeni aumenta il rischio di ipertensione"},"content":{"rendered":"<p>Un recente studio ha rilevato che le donne che assumono pillole di estrogeni come parte della terapia ormonale in menopausa corrono un rischio maggiore di sviluppare ipertensione.<\/p>\n<p>Quando una donna entra in menopausa, le sue ovaie non producono pi\u00f9 alti livelli di estrogeni e progesterone come prima. Questo improvviso calo degli ormoni provoca diversi disagi come vampate di calore, sudorazioni notturne, sbalzi d&#039;umore e difficolt\u00e0 a dormire.<\/p>\n<p>La terapia ormonale sostitutiva \u00e8 spesso raccomandata alle donne in menopausa per alleviare i sintomi e ridurre il rischio di osteoporosi e malattie cardiovascolari associate al calo degli ormoni.<\/p>\n<p>Esistono due tipi principali di h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">terapie ormonali sostitutive<\/a> \u2013 terapia con estrogeni e terapia estroprogesterone\/ormone progestinico (EPT).<\/p>\n<p>La terapia con estrogeni prevede l\u2019uso di estrogeni sotto forma di pillola, cerotto, crema, anello vaginale, gel o spray. L&#039;EPT, nota anche come terapia di combinazione, combina dosi di estrogeni e progesterone.<\/p>\n<p>Il tipo di trattamento ormonale viene deciso in base a diversi fattori, incluso se la paziente ha subito un&#039;isterectomia. Una combinazione di estrogeni e progesterone viene utilizzata nelle donne con utero per ridurre il rischio di cancro dell\u2019endometrio. Tuttavia, si ritiene che il trattamento con soli estrogeni presenti minori rischi a lungo termine rispetto alla terapia di combinazione.<\/p>\n<p>Nell&#039;ultimo <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">studio<\/a>, pubblicato sulla rivista Hypertension dell&#039;American Heart Association, i ricercatori hanno esaminato i dati di oltre 112.000 donne di et\u00e0 pari o superiore a 45 anni dopo essere state sottoposte a terapia ormonale a base di soli estrogeni per un anno.<\/p>\n<p>I ricercatori hanno esaminato la relazione tra il metodo di somministrazione degli estrogeni \u2013 applicazione orale, transdermica e vaginale \u2013 e il rischio di sviluppare ipertensione.<\/p>\n<p>Secondo il <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">ricercatori<\/a>, l&#039;assunzione di estrogeni per via orale ha aumentato il rischio di ipertensione arteriosa di 14% rispetto al trattamento ormonale con creme transdermiche a base di estrogeni. Il rischio delle pillole di estrogeni era di 19% rispetto all&#039;uso di creme o supposte vaginali di estrogeni.<\/p>\n<p>&quot;Sappiamo che gli estrogeni ingeriti per via orale vengono metabolizzati attraverso il fegato e questo \u00e8 associato a un aumento di fattori che possono portare a un aumento della pressione sanguigna&quot;, ha affermato Cindy Kalenga, l&#039;autrice principale dello studio.<\/p>\n<p>Il gruppo di ricerca ha anche scoperto che l\u2019assunzione di estrogeni per un periodo prolungato o l\u2019uso di una dose pi\u00f9 elevata era associata a un rischio maggiore di ipertensione.<\/p>\n<p>&quot;Lo sappiamo <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">post-menopausa<\/a> le donne hanno un rischio maggiore di ipertensione rispetto alle donne in pre-menopausa, inoltre, studi precedenti hanno dimostrato che specifici tipi di terapia ormonale sono stati associati a tassi pi\u00f9 elevati di malattie cardiache. Abbiamo scelto di approfondire i fattori associati alla terapia ormonale, come la via di somministrazione (orale o non orale) e il tipo di estrogeni, e il modo in cui possono influenzare la pressione sanguigna\u201d, ha detto Kalenga.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><picture class=\"mapping-embed\" width=\"736\" height=\"1103\"><source type=\"image\/webp\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/jpeg\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/webp\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/jpeg\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/webp\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"adult\" width=\"736\" height=\"1103\" style=\"display:none\"><\/picture><\/div><figcaption class=\"caption\">\n<span class=\"cap\">La menopausa pu\u00f2 causare di tutto, dalle vampate di calore alla perdita di memoria. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Pubblicato da Medicaldaily.com<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-hypertension-470012\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un recente studio ha rilevato che le donne che assumono pillole di estrogeni come parte della terapia ormonale in menopausa corrono un rischio maggiore di sviluppare ipertensione.<\/p>\n<p>Quando una donna entra in menopausa, le sue ovaie non producono pi\u00f9 alti livelli di estrogeni e progesterone come prima. Questo improvviso calo degli ormoni provoca diversi disagi come vampate di calore, sudorazioni notturne, sbalzi d&#039;umore e difficolt\u00e0 a dormire.<\/p>\n<p>La terapia ormonale sostitutiva \u00e8 spesso raccomandata alle donne in menopausa per alleviare i sintomi e ridurre il rischio di osteoporosi e malattie cardiovascolari associate al calo degli ormoni.<\/p>\n<p>Esistono due tipi principali di h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">terapie ormonali sostitutive<\/a> \u2013 terapia con estrogeni e terapia estroprogesterone\/ormone progestinico (EPT).<\/p>\n<p>La terapia con estrogeni prevede l\u2019uso di estrogeni sotto forma di pillola, cerotto, crema, anello vaginale, gel o spray. L&#039;EPT, nota anche come terapia di combinazione, combina dosi di estrogeni e progesterone.<\/p>\n<p>Il tipo di trattamento ormonale viene deciso in base a diversi fattori, incluso se la paziente ha subito un&#039;isterectomia. Una combinazione di estrogeni e progesterone viene utilizzata nelle donne con utero per ridurre il rischio di cancro dell\u2019endometrio. Tuttavia, si ritiene che il trattamento con soli estrogeni presenti minori rischi a lungo termine rispetto alla terapia di combinazione.<\/p>\n<p>Nell&#039;ultimo <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">studio<\/a>, pubblicato sulla rivista Hypertension dell&#039;American Heart Association, i ricercatori hanno esaminato i dati di oltre 112.000 donne di et\u00e0 pari o superiore a 45 anni dopo essere state sottoposte a terapia ormonale a base di soli estrogeni per un anno.<\/p>\n<p>I ricercatori hanno esaminato la relazione tra il metodo di somministrazione degli estrogeni \u2013 applicazione orale, transdermica e vaginale \u2013 e il rischio di sviluppare ipertensione.<\/p>\n<p>Secondo il <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">ricercatori<\/a>, l&#039;assunzione di estrogeni per via orale ha aumentato il rischio di ipertensione arteriosa di 14% rispetto al trattamento ormonale con creme transdermiche a base di estrogeni. Il rischio delle pillole di estrogeni era di 19% rispetto all&#039;uso di creme o supposte vaginali di estrogeni.<\/p>\n<p>&quot;Sappiamo che gli estrogeni ingeriti per via orale vengono metabolizzati attraverso il fegato e questo \u00e8 associato a un aumento di fattori che possono portare a un aumento della pressione sanguigna&quot;, ha affermato Cindy Kalenga, l&#039;autrice principale dello studio.<\/p>\n<p>Il gruppo di ricerca ha anche scoperto che l\u2019assunzione di estrogeni per un periodo prolungato o l\u2019uso di una dose pi\u00f9 elevata era associata a un rischio maggiore di ipertensione.<\/p>\n<p>&quot;Lo sappiamo <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">post-menopausa<\/a> le donne hanno un rischio maggiore di ipertensione rispetto alle donne in pre-menopausa, inoltre, studi precedenti hanno dimostrato che specifici tipi di terapia ormonale sono stati associati a tassi pi\u00f9 elevati di malattie cardiache. Abbiamo scelto di approfondire i fattori associati alla terapia ormonale, come la via di somministrazione (orale o non orale) e il tipo di estrogeni, e il modo in cui possono influenzare la pressione sanguigna\u201d, ha detto Kalenga.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"adult\" width=\"736\" height=\"1103\"><\/div><figcaption class=\"caption\">\n<span class=\"cap\">La menopausa pu\u00f2 causare di tutto, dalle vampate di calore alla perdita di memoria. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Pubblicato da Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8304,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8303","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/uno-studio-sulla-terapia-ormonale-sostitutiva-afferma-che-lassunzione-di-estrogeni-per-via-orale-aumenta-il-rischio-di-ipertensione\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.&quot;We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,&quot; said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.&quot;We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,&quot; Kalenga said. Menopause can cause everything from hot flashes to memory loss. Pixabay Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/uno-studio-sulla-terapia-ormonale-sostitutiva-afferma-che-lassunzione-di-estrogeni-per-via-orale-aumenta-il-rischio-di-ipertensione\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-06T06:32:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension\",\"datePublished\":\"2023-06-06T06:32:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"wordCount\":455,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"url\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"name\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - 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Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/it\/uno-studio-sulla-terapia-ormonale-sostitutiva-afferma-che-lassunzione-di-estrogeni-per-via-orale-aumenta-il-rischio-di-ipertensione\/","og_locale":"it_IT","og_type":"article","og_title":"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic","og_description":"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.\"We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,\" said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.\"We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,\" Kalenga said. Menopause can cause everything from hot flashes to memory loss. 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