{"id":8301,"date":"2023-06-05T09:24:37","date_gmt":"2023-06-05T06:24:37","guid":{"rendered":"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/"},"modified":"2023-06-05T09:24:37","modified_gmt":"2023-06-05T06:24:37","slug":"ladolescenza-potrebbe-essere-il-momento-migliore-per-curare-lautismo-schizofrenico","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/ladolescenza-potrebbe-essere-il-momento-migliore-per-curare-lautismo-schizofrenico\/","title":{"rendered":"L'adolescenza potrebbe essere il momento migliore per curare la schizofrenia e l'autismo"},"content":{"rendered":"

Gli scienziati hanno identificato una potenziale finestra per il trattamento dei disturbi neuropsichiatrici causati dalla disfunzione della dopamina.<\/p>\n

L'ultimo studio dei ricercatori dell'Universit\u00e0 di Rochester ha scoperto che l'adolescenza \u00e8 il momento migliore per trattare condizioni come la schizofrenia e l'autismo, entrambe caratterizzate da disfunzioni del sistema della dopamina.<\/p>\n

Gli individui autistici hanno bassi livelli<\/a> di dopamina. Gli studi dimostrano che ci\u00f2 potrebbe ridurre la loro motivazione a perseguire interazioni sociali poich\u00e9 il loro cervello registra queste attivit\u00e0 come non gratificanti.<\/p>\n

Negli individui schizofrenici, livelli di dopamina<\/a> pu\u00f2 essere troppo alto o troppo basso. L'aumento anormale dell'attivit\u00e0 della dopamina in alcune parti del cervello provoca sintomi positivi della schizofrenia come allucinazioni o deliri. I sintomi positivi si riferiscono a cambiamenti nei comportamenti o nei pensieri dopo che un individuo sviluppa la schizofrenia.<\/p>\n

Quando l'attivit\u00e0 della dopamina \u00e8 troppo bassa in alcune parti del cervello, i pazienti schizofrenici possono manifestarsi sintomi negativi<\/a> e sintomi cognitivi. I sintomi negativi sono contrassegnati dall'assenza di un comportamento normale, mentre i sintomi cognitivi includono problemi di concentrazione e attenzione.<\/p>\n

Nell'ultimo studio<\/a>, i ricercatori hanno stimolato le cellule neuronali con prestazioni insufficienti che forniscono dopamina alla corteccia frontale del cervello nei topi. Hanno scoperto che l'attivazione aiuta a rafforzare il circuito essenziale per l'elaborazione cognitiva e il processo decisionale superiori.<\/p>\n

In uno studio precedente, il team ha identificato che il braccio specifico del sistema della dopamina era pi\u00f9 flessibile nel cervello degli adolescenti che negli adulti. L'ultimo studio suggerisce che questa finestra \u00e8 un'opportunit\u00e0 per un intervento terapeutico.<\/p>\n

\u201cLo sviluppo del cervello \u00e8 un processo lungo e molti sistemi neuronali hanno finestre critiche, momenti chiave in cui le aree cerebrali sono malleabili e stanno attraversando fasi finali di maturazione. Identificando queste finestre, possiamo indirizzare gli interventi a questi periodi di tempo e possibilmente cambiare il corso di una malattia salvando i deficit strutturali e comportamentali causati da questi disturbi\u00bb. disse<\/a> Rianne Stowell, co-primo autore dello studio.<\/p>\n

I ricercatori ritengono che la scoperta li porter\u00e0 un passo avanti verso la ricerca di un possibile bersaglio per il trattamento dei disturbi neuropsichiatrici.<\/p>\n

\u201cQuesti risultati suggeriscono che l'aumento dell'attivit\u00e0 del circuito dopaminergico adolescenziale pu\u00f2 salvare i deficit esistenti nel circuito e che questo effetto pu\u00f2 durare a lungo poich\u00e9 questi cambiamenti persistono nell'et\u00e0 adulta. Se riusciamo a individuare le finestre giuste nello sviluppo e a comprendere i segnali in gioco, possiamo sviluppare trattamenti che cambiano il corso di questi disturbi cerebrali", ha aggiunto Stowell.<\/p>\n

\n
\"teenager\"<\/picture><\/div>
\nL'adolescenza \u00e8 il momento migliore per trattare condizioni come la schizofrenia e l'autismo, ha scoperto uno studio.<\/span>
\nFoto per gentile concessione di Pexels<\/span>
\n<\/figcaption><\/figure>\n

Pubblicato da Medicaldaily.com<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Gli scienziati hanno identificato una potenziale finestra per il trattamento dei disturbi neuropsichiatrici causati dalla disfunzione della dopamina.<\/p>\n

L'ultimo studio dei ricercatori dell'Universit\u00e0 di Rochester ha scoperto che l'adolescenza \u00e8 il momento migliore per trattare condizioni come la schizofrenia e l'autismo, entrambe caratterizzate da disfunzioni del sistema della dopamina.<\/p>\n

Gli individui autistici hanno bassi livelli<\/a> di dopamina. Gli studi dimostrano che ci\u00f2 potrebbe ridurre la loro motivazione a perseguire interazioni sociali poich\u00e9 il loro cervello registra queste attivit\u00e0 come non gratificanti.<\/p>\n

Negli individui schizofrenici, livelli di dopamina<\/a> pu\u00f2 essere troppo alto o troppo basso. L'aumento anormale dell'attivit\u00e0 della dopamina in alcune parti del cervello provoca sintomi positivi della schizofrenia come allucinazioni o deliri. I sintomi positivi si riferiscono a cambiamenti nei comportamenti o nei pensieri dopo che un individuo sviluppa la schizofrenia.<\/p>\n

Quando l'attivit\u00e0 della dopamina \u00e8 troppo bassa in alcune parti del cervello, i pazienti schizofrenici possono manifestarsi sintomi negativi<\/a> e sintomi cognitivi. I sintomi negativi sono contrassegnati dall'assenza di un comportamento normale, mentre i sintomi cognitivi includono problemi di concentrazione e attenzione.<\/p>\n

Nell'ultimo studio<\/a>, i ricercatori hanno stimolato le cellule neuronali con prestazioni insufficienti che forniscono dopamina alla corteccia frontale del cervello nei topi. Hanno scoperto che l'attivazione aiuta a rafforzare il circuito essenziale per l'elaborazione cognitiva e il processo decisionale superiori.<\/p>\n

In uno studio precedente, il team ha identificato che il braccio specifico del sistema della dopamina era pi\u00f9 flessibile nel cervello degli adolescenti che negli adulti. L'ultimo studio suggerisce che questa finestra \u00e8 un'opportunit\u00e0 per un intervento terapeutico.<\/p>\n

\u201cLo sviluppo del cervello \u00e8 un processo lungo e molti sistemi neuronali hanno finestre critiche, momenti chiave in cui le aree cerebrali sono malleabili e stanno attraversando fasi finali di maturazione. Identificando queste finestre, possiamo indirizzare gli interventi a questi periodi di tempo e possibilmente cambiare il corso di una malattia salvando i deficit strutturali e comportamentali causati da questi disturbi\u00bb. disse<\/a> Rianne Stowell, co-primo autore dello studio.<\/p>\n

I ricercatori ritengono che la scoperta li porter\u00e0 un passo avanti verso la ricerca di un possibile bersaglio per il trattamento dei disturbi neuropsichiatrici.<\/p>\n

\u201cQuesti risultati suggeriscono che l'aumento dell'attivit\u00e0 del circuito dopaminergico adolescenziale pu\u00f2 salvare i deficit esistenti nel circuito e che questo effetto pu\u00f2 durare a lungo poich\u00e9 questi cambiamenti persistono nell'et\u00e0 adulta. Se riusciamo a individuare le finestre giuste nello sviluppo e a comprendere i segnali in gioco, possiamo sviluppare trattamenti che cambiano il corso di questi disturbi cerebrali", ha aggiunto Stowell.<\/p>\n

\n
\"teenager\"<\/div>
\nL'adolescenza \u00e8 il momento migliore per trattare condizioni come la schizofrenia e l'autismo, ha scoperto uno studio.<\/span>
\nFoto per gentile concessione di Pexels<\/span>
\n<\/figcaption><\/figure>\n

Pubblicato da Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8302,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8301","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nAdolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/ladolescenza-potrebbe-essere-il-momento-migliore-per-curare-lautismo-schizofrenico\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Scientists have identified a potential window for treating neuropsychiatric disorders caused by dopamine dysfunction.The latest study by researchers from the University of Rochester has found that adolescence is the best time to treat conditions such as schizophrenia and autism, both characterized by dysfunctioning of the dopamine system.Autistic individuals have low levels of dopamine. Studies show this could reduce their motivation to pursue social interactions as their brains register these activities as not rewarding.In schizophrenic individuals, dopamine levels can either be too high or too low. Abnormal increase in dopamine activity in certain parts of the brain causes positive symptoms of schizophrenia such as hallucinations or delusions. Positive symptoms refer to changes in behaviors or thoughts after an individual develops schizophrenia.When dopamine activity is too low in certain parts of the brain, schizophrenic patients can show negative symptoms and cognitive symptoms. Negative symptoms are marked by the absence of normal behavior, while cognitive symptoms include issues with focusing and attention.In the latest study, researchers stimulated the underperforming neuron cells that provide dopamine to the frontal cortex of the brain in mice. They found that the activation helps in strengthening the circuit essential for higher cognitive processing and decision-making.In a previous study, the team identified the specific arm of the dopamine system was more flexible in the adolescent brain than in adults. The latest study suggests this window is an opportunity for therapeutic intervention."Brain development is a lengthy process, and many neuronal systems have critical windows \u2013 key times when brain areas are malleable and undergoing final maturation steps. By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders," said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders."These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders," Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. Photo Courtesy of Pexels Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/ladolescenza-potrebbe-essere-il-momento-migliore-per-curare-lautismo-schizofrenico\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-05T06:24:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism\",\"datePublished\":\"2023-06-05T06:24:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"wordCount\":420,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"url\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"name\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - 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By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders,\" said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders.\"These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders,\" Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. 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