{"id":7746,"date":"2023-04-04T13:20:36","date_gmt":"2023-04-04T10:20:36","guid":{"rendered":"https:\/\/urbancare.clinic\/minnesota-man-dies-of-rabies-despite-receiving-post-exposure-treatment\/"},"modified":"2023-04-04T13:20:36","modified_gmt":"2023-04-04T10:20:36","slug":"un-uomo-del-minnesota-muore-di-rabbia-nonostante-abbia-ricevuto-cure-post-esposizione","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/un-uomo-del-minnesota-muore-di-rabbia-nonostante-abbia-ricevuto-cure-post-esposizione\/","title":{"rendered":"Un uomo del Minnesota muore di rabbia nonostante abbia ricevuto cure post-esposizione"},"content":{"rendered":"

Secondo quanto riferito, un uomo di 84 anni nel Minnesota \u00e8 morto a causa della rabbia nonostante avesse ricevuto un adeguato trattamento post-esposizione.<\/p>\n

In un caso clinico recentemente pubblicato su Malattie infettive cliniche<\/a>, gli esperti hanno discusso di cosa sia successo all'anziano e di cosa potrebbe essere responsabile della sua morte nonostante avesse ricevuto la giusta terapia contro il virus.<\/p>\n

Secondo gli autori, il paziente maschio \u00e8 morto nel gennaio 2021, sei mesi dopo essere stato morso da un pipistrello rabbioso. Prima di ci\u00f2, negli Stati Uniti non era stata documentata alcuna profilassi antirabbica post-esposizione (PEP) negli esseri umani utilizzando moderni vaccini costituiti da colture cellulari.<\/p>\n

Gli scienziati hanno utilizzato diversi metodi per indagare sulla causa dell\u2019infezione rivoluzionaria. Hanno esaminato le cartelle cliniche, i risultati di laboratorio e i risultati dell\u2019autopsia. Hanno anche eseguito il sequenziamento dell\u2019intero genoma per confrontare le sequenze del virus del paziente e del pipistrello. I campioni delle immunoglobuline antirabbiche rimanenti sono stati persino esaminati per verificarne la potenza.<\/p>\n

Gli autori hanno scoperto che il paziente aveva una \u201cgammopatia monoclonale non riconosciuta di significato sconosciuto\u201d. Hanno inoltre notato che gli anticorpi del virus nel siero e nel liquido cerebrospinale del paziente non erano neutralizzanti.<\/p>\n

\u201cQuesto \u00e8 il primo caso segnalato di fallimento di un\u2019appropriata terapia di profilassi antirabbica dall\u2019inizio di tale terapia. Questo sfortunato individuo aveva una deficienza immunitaria non riconosciuta che probabilmente ha contribuito al fallimento", ha detto il dottor Aaron Glatt, che non faceva parte del rapporto. Fox Notizie digitale<\/a>.<\/p>\n

Glatt \u00e8 il primario del reparto malattie infettive del Mount Sinai South Nassau Hospital di Long Island, New York. Ha assicurato che la terapia PEP ha un grande successo nella prevenzione della rabbia se somministrata al momento giusto, ovvero prima della comparsa dei sintomi.<\/p>\n

\u201cIl fallimento del vaccino primario mediato dall\u2019ospite, attribuito a un\u2019immunit\u00e0 compromessa precedentemente non riconosciuta, \u00e8 la spiegazione pi\u00f9 probabile per questa infezione rivoluzionaria. I medici dovrebbero prendere in considerazione la misurazione dei titoli anticorpali neutralizzanti la rabbia dopo il completamento della PEP se vi \u00e8 il sospetto di immunocompromissione\u201d, hanno concluso gli autori.<\/p>\n

A parte il problema dell\u2019immunit\u00e0, l\u2019uomo che si \u00e8 svegliato il 27 luglio 2020, quando un pipistrello gli ha morso la mano destra, aveva anche una malattia coronarica, diabete di tipo 2 controllato, ipertensione, iperlipidemia, malattia renale cronica e ingrossamento della prostata.<\/p>\n

Secondo il Centri per il controllo e la prevenzione delle malattie<\/a> (CDC), circa 59.000 persone muoiono di rabbia ogni anno in tutto il mondo. Negli Stati Uniti, i casi di rabbia umana sono considerati rari, con solo da 1 a 3 casi segnalati ogni anno. Tuttavia, tra 30.000 e 60.000<\/a> le persone nel paese ricevono il PEP ogni anno.<\/p>\n

\n
\"Pipistrello<\/picture><\/div>
\nLa rabbia dei pipistrelli vampiri colpisce migliaia di persone in tutta l\u2019America Latina, contribuendo a 960 morti ogni 100.000 residenti.<\/span>
\nUwe Schmidt\/Wikimedia Commons<\/span>
\n<\/figcaption><\/figure>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Un esperto ha detto che l\u2019uomo aveva una deficienza immunitaria non riconosciuta che ha portato al fallimento del vaccino.<\/p>","protected":false},"author":2,"featured_media":7747,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/04\/minnesota-man-dies-of-rabies-despite-receiving-post-exposure-treatment.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-7746","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nMinnesota Man Dies Of Rabies Despite Receiving Post-Exposure Treatment - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/un-uomo-del-minnesota-muore-di-rabbia-nonostante-abbia-ricevuto-cure-post-esposizione\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Minnesota Man Dies Of Rabies Despite Receiving Post-Exposure Treatment - 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