{"id":7678,"date":"2023-03-15T12:43:51","date_gmt":"2023-03-15T09:43:51","guid":{"rendered":"https:\/\/urbancare.clinic\/cholesterol-lowering-medication-can-protect-heart-health-of-people-with-sleep-apnea-study\/"},"modified":"2023-05-23T17:37:47","modified_gmt":"2023-05-23T14:37:47","slug":"i-farmaci-per-abbassare-il-colesterolo-possono-proteggere-la-salute-del-cuore-delle-persone-affette-da-uno-studio-sullapnea-notturna","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/cholesterol-lowering-medication-can-protect-heart-health-of-people-with-sleep-apnea-study\/","title":{"rendered":"I farmaci per abbassare il colesterolo possono proteggere la salute del cuore delle persone con apnea notturna: studio"},"content":{"rendered":"
<\/div>\n

Un nuovo studio condotto dai ricercatori della Columbia University ha scoperto che i farmaci per abbassare il colesterolo chiamati statine possono eventualmente ridurre le possibilit\u00e0 di gravi malattie cardiache nelle persone con apnea notturna.<\/p>\n

L'apnea notturna \u00e8 una condizione comune riscontrata negli anziani. Al suo risveglio, le persone incontrano difficolt\u00e0 nell'addormentarsi, il che a sua volta porta all'ipertensione e infine a una serie di malattie cardiache come aritmie cardiache (battiti cardiaci irregolari), infarti e ictus.<\/p>\n

Lo studio, pubblicato<\/a> nella rivista Annals of the American Thoracic Society, suggerisce che il farmaco pu\u00f2 essere utile anche per coloro che utilizzano dispositivi a pressione positiva continua delle vie aeree (CPAP) per facilitare un normale ordine del sonno, come da Medico espresso.<\/a><\/p>\n

CPAP fornisce un sonno ristoratore a chi soffre di apnea ostruttiva del sonno riducendo l'affaticamento diurno, ma recenti studi clinici hanno dimostrato che non ha il potenziale per migliorare la salute del cuore come i medici hanno erroneamente ipotizzato.<\/p>\n

<\/div>\n

Pertanto, i medici hanno sentito il bisogno immediato di cercare un'alternativa migliore poich\u00e9 la condizione triplica le possibilit\u00e0 di malattie cardiache, ictus o altri effetti cardiovascolari. Lo studio, condotto da Sanja Jelic, professore associato di medicina presso il Vagelos College of Physicians and Surgeons della Columbia University, ha scoperto che le statine sono uno di questi metodi.<\/p>\n

Lo studio ha coinvolto 87 persone con apnea notturna rilevata di recente, che usano CPAP. Ai pazienti sono state somministrate in modo casuale statine o un placebo. I ricercatori hanno notato che le statine e non la CPAP proteggevano i vasi sanguigni dai pericolosi cambiamenti infiammatori che si verificano nelle persone con apnea notturna.<\/p>\n

Nell'ambito dello studio, i ricercatori hanno notato che livelli pi\u00f9 bassi di colesterolo possono stabilizzare i livelli della proteina CD59, un componente che tiene sotto controllo l'infiammazione nei vasi sanguigni proteggendo le cellule dall'attivit\u00e0 del complemento (un gruppo di proteine che promuovono l'infiammazione). I medici hanno notato che i partecipanti allo studio avevano livelli pi\u00f9 stabilizzati di CD59 nel sangue dopo quattro settimane di terapia con statine per abbassare il colesterolo, cosa che il CPAP da solo non poteva fare.<\/p>\n

"L'effetto che abbiamo riscontrato con le statine \u00e8 importante", afferma Jelic, secondo Recensione del sonno.<\/a> "L'infiammazione nei vasi sanguigni \u00e8 un passaggio chiave nella progressione delle malattie cardiovascolari, quindi tutto ci\u00f2 che possiamo fare per stabilizzare il CD59 in questi pazienti pu\u00f2 essere benefico per la salute del cuore".<\/p>\n

I medici hanno anche scoperto che CPAP fa pi\u00f9 male che bene in quanto aumenta i livelli di angiopoietina-2 nel sangue. L'angiopoietina-2 \u00e8 una proteina legata all'aumento dell'infiammazione e ad altre malattie cardiache. Durante lo studio, le statine hanno abbassato i livelli di angiopoietina-2 nei pazienti con apnea notturna.<\/p>\n

"Continuiamo a credere che CPAP sia molto utile poich\u00e9 migliora il sonno e riduce l'affaticamento diurno", afferma Jelic. \u201cMa la CPAP sembra avere anche effetti negativi sul sistema cardiovascolare. Dobbiamo indagare se dovremmo usare pressioni delle vie aeree pi\u00f9 conservative o altri trattamenti meno utilizzati come apparecchi orali per trattare i pazienti con apnea ostruttiva del sonno\u201d.<\/p>\n

Sono necessari ulteriori studi clinici sulla terapia con statine per dare un verdetto definitivo sulla sua efficacia nella cura delle malattie cardiache, ha detto Jelic. Attualmente, le statine sono prescritte solo a 8-13% del numero complessivo di pazienti con apnea notturna.<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

I ricercatori hanno notato che le statine proteggono i vasi sanguigni dai pericolosi cambiamenti infiammatori che si verificano nelle persone con apnea notturna.<\/p>","protected":false},"author":2,"featured_media":7679,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/03\/cholesterol-lowering-medication-can-protect-heart-health-of-people-with-sleep-apnea-study.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[198],"class_list":["post-7678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-blood-pressure"],"yoast_head":"\nCholesterol-Lowering Medication Can Protect Heart Health Of People With Sleep Apnea: Study - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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