{"id":7531,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/leonine-facies-and-madarosis-in-lepromatous-leprosy\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"facies-leonina-e-madarosi-nella-lebbra-lepromatosa","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/leonine-facies-and-madarosis-in-lepromatous-leprosy\/","title":{"rendered":"Facies leonina e madarosi nella lebbra lepromatosa"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un uomo di 69 anni si presentava con una storia di 5 anni di infiltrazione diffusa della pelle e progressiva perdita sensoriale sulle sue mani bilaterali. Il volto presentava alcune lesioni papulo-nodulari su fronte e guance, pliche cutanee attenuate, con perdita di ciglia e sopracciglia (figura 1). L&#039;esame dei nervi periferici mostrava un ispessimento dei nervi ulnari bilaterali e dei nervi tibiali posteriori. L&#039;esame dello striscio cutaneo della fessura e l&#039;istopatologia di un nodulo hanno mostrato caratteristiche coerenti con multibacillare... <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e36?rss=1\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un uomo di 69 anni si \u00e8 presentato con un&#039;anamnesi di 5 anni di diffusa infiltrazione cutanea e progressiva perdita sensoriale sulle mani bilaterali. Il volto presentava alcune lesioni papulo-nodulari sulla fronte e sulle guance, pieghe cutanee attenuate, con perdita di ciglia e sopracciglia (<cross-ref type=\"fig\" refid=\"F1\">Figura 1<\/cross-ref>). L&#039;esame dei nervi periferici mostrava un ispessimento dei nervi ulnare bilaterale e tibiale posteriore. L&#039;esame dello striscio cutaneo e l&#039;istopatologia di un nodulo hanno mostrato caratteristiche coerenti con la lebbra multibacillare. Sulla base dei risultati clinici e di laboratorio, la diagnosi di lebbra lepromatosa \u00e8 stata fatta e avviata con il regime di terapia multifarmaco dell&#039;OMS contenente rifampicina, clofazimina e dapsone. Il nostro paziente aveva la caratteristica facies leonina e la madarosi della lebbra lepomatosa.<\/p>\n<p>La facies leonina \u00e8 un volto che ricorda quello del leone.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref> Si verifica in seguito ad un&#039;infiltrazione diffusa (ispessimento) della pelle della fronte, del naso, delle orecchie e del mento con aspetto ceroso e attenuazione delle linee naturali. \u00c8 stata classicamente descritta nella lepromatosi...<\/p>","protected":false},"author":2,"featured_media":7532,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7531","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Leonine facies and madarosis in lepromatous leprosy - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/facies-leonina-e-madarosi-nella-lebbra-lepromatosa\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leonine facies and madarosis in lepromatous leprosy - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 69-year-old man presented with a 5-year history of diffuse infiltration of skin and progressive sensory loss over his bilateral hands. His face had a few papular-nodular lesions over forehead and cheeks, attenuated skin folds, with loss of eyelashes and eyebrows (figure 1). Peripheral nerve examination showed thickened bilateral ulnar and posterior tibial nerves. Slit skin smear examination and histopathology of a nodule showed features consistent with multibacillary leprosy. Based on clinical and laboratorial findings, the diagnosis of lepromatous leprosy was made and started on WHO&mdash;Multi Drug Therapy regimen containing rifampicin, clofazimine and dapsone. Our patient had characteristic leonine facies and madarosis of lepomatous leprosy. Leonine facies is a face that resembles that of lion.1 It occurs secondary to diffuse infiltration (thickening) of skin of forehead, nose, ears and chin with waxy appearance and attenuation of natural lines. It has been classically described in lepromatous...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/facies-leonina-e-madarosi-nella-lebbra-lepromatosa\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Leonine facies and madarosis in lepromatous leprosy\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\"},\"wordCount\":77,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\",\"name\":\"Leonine facies and madarosis in lepromatous leprosy - 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