{"id":7523,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"leontiasi-ossea-uremica","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/uremic-leontiasis-ossea\/","title":{"rendered":"Leontiasi uremica ossea"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un uomo di 40 anni presentava una storia di 5 anni di progressivi cambiamenti facciali e difficolt\u00e0 a masticare. Aveva una storia di malattia renale cronica ed \u00e8 diventato dipendente dalla dialisi all&#039;et\u00e0 di 17 anni. All&#039;esame \u00e8 stata osservata mascella superiore sporgente con malocclusione. Il suo livello di ormone paratiroideo intatto superava i 2500 pg\/ml (intervallo di riferimento: 15,6-68,3). La TC del volto mostrava un ispessimento dell&#039;osso cranico,... <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e37?rss=1\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un uomo di 40 anni si \u00e8 presentato con una storia di 5 anni di cambiamenti facciali progressivi e difficolt\u00e0 di masticazione. Aveva una storia di malattia renale cronica ed era diventato dipendente dalla dialisi all&#039;et\u00e0 di 17 anni. All&#039;esame, \u00e8 stata osservata una mascella superiore sporgente con malocclusione. Il suo livello di ormone paratiroideo intatto superava i 2500 pg\/mL (intervallo di riferimento: 15,6-68,3). La TC del viso ha mostrato un ispessimento delle ossa craniche e una crescita eccessiva della mascella e della mandibola (<cross-ref type=\"fig\" refid=\"F1\">figura 1A,B<\/cross-ref>). L&#039;aspetto di sale e pepe \u00e8 stato osservato nella calotta cranica (<cross-ref type=\"fig\" refid=\"F1\">figura 1B<\/cross-ref>, freccia). Questi risultati erano coerenti con la leontiasi ossea uremica, una forma rara e grave di osteodistrofia renale dovuta a iperparatiroidismo.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref><\/p>\n<p>La leontiasi ossea, nota anche come faccia di leone, non provoca solo la deturpazione del paziente, ma l&#039;espansione ossea pu\u00f2 anche comprimere le strutture facciali vicine, come la cavit\u00e0 nasale e orale, causando ostruzione delle vie aeree, disartria e disfagia (<cross-ref type=\"fig\" refid=\"F1\">figura 1C<\/cross-ref>,&#8230;<\/p>","protected":false},"author":2,"featured_media":7524,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Uremic leontiasis ossea - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/leontiasi-ossea-uremica\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Uremic leontiasis ossea - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 40-year-old man presented with a 5-year history of progressive facial changes and difficulty chewing. He had a history of chronic kidney disease and became dialysis dependent at the age of 17. On examination, protruding upper jaw with malocclusion was observed. His intact parathyroid hormone level exceeded 2500 pg\/mL (reference range: 15.6&ndash;68.3). CT of the face showed cranial bone thickening, and overgrowth of the maxilla and mandible (figure 1A,B). Salt and pepper appearance was seen in the calvaria (figure 1B, arrow). These findings were consistent with uremic leontiasis ossea, a rare and severe form of renal osteodystrophy due to hyperparathyroidism.1 Leontiasis ossea&mdash;also known as lion face&mdash;results in not only disfigurement of the patient, but also the bony expansion may also compress the nearby facial structures, such as the nasal and oral cavity, leading to airway obstruction, dysarthria and dysphagia (figure 1C,...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/leontiasi-ossea-uremica\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Uremic leontiasis ossea\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"wordCount\":64,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/uremic-leontiasis-ossea.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"name\":\"Uremic leontiasis ossea - 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