{"id":7515,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/multifocal-nodular-steatosis-mimicking-malignancy\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"steatosi-nodulare-multifocale-che-imita-la-malignita","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/multifocal-nodular-steatosis-mimicking-malignancy\/","title":{"rendered":"Steatosi nodulare multifocale che imita la malignit\u00e0"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un uomo precedentemente in forma si \u00e8 presentato con affanno. La radiografia del torace ha mostrato la densit\u00e0 del lobo inferiore destro. I test di funzionalit\u00e0 epatica, gli studi di coagulazione ei livelli di alfafetoproteina erano irrilevanti. La dispnea del paziente si \u00e8 risolta da sola, ma la TC torace-addome-bacino eseguita per escludere la malignit\u00e0 ha rivelato lesioni epatiche ipodense multiple relative alle metastasi (figura 1). La biopsia epatica percutanea ecoguidata mirata a queste lesioni \u00e8 stata eseguita con successo. L&#039;istologia ha mostrato un cambiamento grasso ma nessuna evidenza di malignit\u00e0. Per evitare la possibilit\u00e0 di campionamento... <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e33?rss=1\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un uomo precedentemente in forma si \u00e8 presentato con affanno. La radiografia del torace ha mostrato la densit\u00e0 del lobo inferiore destro. I test di funzionalit\u00e0 epatica, gli studi di coagulazione ei livelli di alfafetoproteina erano irrilevanti. La dispnea del paziente si \u00e8 risolta da sola, ma la TC torace-addome-pelvi eseguita per escludere la malignit\u00e0 ha rivelato molteplici lesioni epatiche ipodense relative alle metastasi (<cross-ref type=\"fig\" refid=\"F1\">Figura 1<\/cross-ref>). La biopsia epatica percutanea ecoguidata mirata a queste lesioni \u00e8 stata eseguita con successo. L&#039;istologia ha mostrato un cambiamento grasso ma nessuna evidenza di malignit\u00e0. Per evitare la possibilit\u00e0 di errore di campionamento, \u00e8 stata eseguita una seconda biopsia ecoguidata delle lesioni. Ancora una volta, non \u00e8 stato identificato alcun tessuto maligno. \u00c8 stata eseguita la risonanza magnetica del fegato (<cross-ref type=\"fig\" refid=\"F2\">figura 2A,B<\/cross-ref>). Le immagini fuori fase hanno mostrato un&#039;interruzione del segnale nel mezzo delle lesioni (<cross-ref type=\"fig\" refid=\"F2\">figura 2B<\/cross-ref>), indicativo di contenuto lipidico intracellulare e suggestivo di cambiamento steatosico. Il paziente \u00e8 stato diagnosticato con steatosi nodulare multifocale (MNS), rassicurato e dimesso.<\/p>\n<p>Le lesioni MNS possono essere difficili da distinguere dalla malattia metastatica perch\u00e9...<\/p>","protected":false},"author":2,"featured_media":7516,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7515","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multifocal nodular steatosis mimicking malignancy - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/steatosi-nodulare-multifocale-che-imita-la-malignita\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multifocal nodular steatosis mimicking malignancy - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A previously fit man presented with breathlessness. Chest radiography showed right lower lobe density. Liver function tests, coagulation studies and alphafetoprotein levels were unremarkable. The patient&#039;s breathlessness self-resolved, but chest&ndash;abdomen&ndash;pelvis CT performed to exclude malignancy revealed multiple hypodense liver lesions concerning for metastases (figure 1). Ultrasound-guided percutaneous liver biopsy targeting these lesions was successfully carried out. Histology showed fatty change but no evidence of malignancy. To avoid the possibility of sampling error, a second ultrasound-guided biopsy of the lesions was performed. Again, no malignant tissue was identified. MRI of the liver was performed (figure 2A,B). The out-of-phase images showed signal drop-out in the middle of the lesions (figure 2B), indicative of intracellular lipid content and suggestive of steatotic change. The patient was diagnosed with multifocal nodular steatosis (MNS), reassured and discharged. MNS lesions can be difficult to distinguish from metastatic disease because they...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/steatosi-nodulare-multifocale-che-imita-la-malignita\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Multifocal nodular steatosis mimicking malignancy\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\"},\"wordCount\":81,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\",\"name\":\"Multifocal nodular steatosis mimicking malignancy - 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