{"id":7505,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/muscle-involvement-in-sarcoidosis\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"coinvolgimento-muscolare-nella-sarcoidosi","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/muscle-involvement-in-sarcoidosis\/","title":{"rendered":"Coinvolgimento muscolare nella sarcoidosi"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/muscle-involvement-in-sarcoidosis.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un uomo di 31 anni si \u00e8 presentato con tosse secca della durata di 2 mesi. \u00c8 stato riscontrato che aveva un&#039;adenopatia mediastinica, livelli elevati di calcio sierico e ACE. \u00c8 stato sottoposto a biopsia endoscopica ecoguidata dei linfonodi sottocarenali e peripancreatici, che hanno mostrato granulomi discreti non caseosi. \u00c8 stata fatta una diagnosi di sarcoidosi ed \u00e8 stato sottoposto a una tomografia a emissione di positroni con fluorodesossiglucosio (FDG PET) di tutto il corpo per valutare l&#039;attivit\u00e0 della malattia in altre parti del corpo. Ha rivelato il\u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e31?rss=1\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>A 31-year-old man presented with dry cough of 2 months duration. He was detected to have mediastinal adenopathy, raised serum calcium and ACE levels. He underwent endoscopic ultrasound-guided biopsy from subcarinal and peripancreatic nodes, which showed discrete non-caseating granulomas. A diagnosis of sarcoidosis was made and he underwent a whole-body fluorodeoxyglucose-positron emission tomography (FDG PET) scan to assess disease activity elsewhere. It revealed the presence of FDG avid right cervical, mediastinal and retroperitoneal lymphadenopathy (<cross-ref type=\"fig\" refid=\"F1\">Figura 1<\/cross-ref> green arrows). Poorly defined hypoenhancing multiple intramuscular nodular lesions with spotty intense FDG uptake were also noted (<cross-ref type=\"fig\" refid=\"F1\">Figura 1<\/cross-ref> blue arrow and <cross-ref type=\"fig\" refid=\"F2\">figura 2<\/cross-ref> white arrow). Skeletal muscle involvement occurs subclinically in as high as 50% to 80% of individuals with sarcoidosis but is very infrequently (0.5% to 2.5%) symptomatic.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref> <sup>18<\/sup>F-FDG-PET scans can identify active sarcoid. The findings include a patchy pickup in the skeletal muscle,&#8230;<\/p>","protected":false},"author":2,"featured_media":7506,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/muscle-involvement-in-sarcoidosis.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Muscle involvement in sarcoidosis - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/coinvolgimento-muscolare-nella-sarcoidosi\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Muscle involvement in sarcoidosis - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 31-year-old man presented with dry cough of 2 months duration. He was detected to have mediastinal adenopathy, raised serum calcium and ACE levels. He underwent endoscopic ultrasound-guided biopsy from subcarinal and peripancreatic nodes, which showed discrete non-caseating granulomas. A diagnosis of sarcoidosis was made and he underwent a whole-body fluorodeoxyglucose-positron emission tomography (FDG PET) scan to assess disease activity elsewhere. It revealed the presence of FDG avid right cervical, mediastinal and retroperitoneal lymphadenopathy (figure 1 green arrows). Poorly defined hypoenhancing multiple intramuscular nodular lesions with spotty intense FDG uptake were also noted (figure 1 blue arrow and figure 2 white arrow). Skeletal muscle involvement occurs subclinically in as high as 50% to 80% of individuals with sarcoidosis but is very infrequently (0.5% to 2.5%) symptomatic.1 18F-FDG-PET scans can identify active sarcoid. The findings include a patchy pickup in the skeletal muscle,...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/coinvolgimento-muscolare-nella-sarcoidosi\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/muscle-involvement-in-sarcoidosis.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Muscle involvement in sarcoidosis\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/\"},\"wordCount\":70,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/muscle-involvement-in-sarcoidosis.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/muscle-involvement-in-sarcoidosis\\\/\",\"name\":\"Muscle involvement in sarcoidosis - 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