{"id":7483,"date":"2023-01-26T13:13:23","date_gmt":"2023-01-26T10:13:23","guid":{"rendered":"https:\/\/urbancare.clinic\/this-cancer-drug-can-increase-longevity-study-finds\/"},"modified":"2023-05-23T17:38:27","modified_gmt":"2023-05-23T14:38:27","slug":"questo-farmaco-antitumorale-puo-aumentare-i-risultati-degli-studi-sulla-longevita","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/this-cancer-drug-can-increase-longevity-study-finds\/","title":{"rendered":"Questo farmaco antitumorale pu\u00f2 aumentare la longevit\u00e0, secondo uno studio"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/this-cancer-drug-can-increase-longevity-study-finds.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>Un nuovo studio ha scoperto che un particolare farmaco antitumorale ha la capacit\u00e0 di prolungare la durata della vita. La scoperta \u00e8 una boccata d\u2019ossigeno per gli scienziati che corrono contro il tempo.<\/p>\n<p>Lo studio, pubblicato sulla rivista <a href=\"https:\/\/dx.doi.org\/10.1038\/s43587-022-00349-y\" rel=\"nofollow noopener\" target=\"_blank\">Invecchiamento naturale<\/a>, hanno dimostrato che il trattamento a lungo termine di topi sani di mezza et\u00e0 (un anno) con un farmaco antitumorale pu\u00f2 aumentare la loro durata di vita in media di 10%, ovvero circa tre anni.<\/p>\n<p>Nello studio, condotto da ricercatori dell&#039;Universit\u00e0 di Auckland, i topi sono stati divisi in due gruppi. Entrambi i gruppi sono stati nutriti con la stessa dieta, con l&#039;aggiunta di un farmaco chiamato alpelisib nel pasto del gruppo testato. I topi nutriti con la dieta contenente farmaci hanno vissuto pi\u00f9 a lungo e hanno anche mostrato un miglioramento della coordinazione e della forza in et\u00e0 avanzata.<\/p>\n<p>&quot;L&#039;invecchiamento non riguarda solo la durata della vita, ma anche la qualit\u00e0 della vita&quot;, ha affermato il ricercatore Dr. Chris Hedges, secondo <a href=\"https:\/\/medicalxpress.com\/news\/2023-01-scientists-drug-lifespan.html\" rel=\"nofollow noopener\" target=\"_blank\">MedicalXpress<\/a>. \u201cPertanto, siamo stati lieti di vedere che questo trattamento farmacologico non solo ha aumentato la longevit\u00e0 dei topi, ma ha anche mostrato molti segni di un invecchiamento pi\u00f9 sano. Stiamo lavorando ora per capire come ci\u00f2 avvenga\u201d.<\/p>\n<div id=\"dfp-ad-oop2\" class=\"dfp-tag-wrapper\"> <\/div>\n<p>Tuttavia, i ricercatori hanno messo in guardia dal trarre troppo vantaggio dai risultati. \u00c8 da notare che i topi trattati con il farmaco presentavano anche alcuni marcatori negativi dell\u2019invecchiamento, come una minore massa ossea.<\/p>\n<p>\u201cNon stiamo suggerendo che qualcuno debba assumere questo farmaco a lungo termine per prolungare la durata della vita, poich\u00e9 ci sono alcuni effetti collaterali. Tuttavia, questo lavoro identifica meccanismi cruciali per l\u2019invecchiamento che saranno utili nei nostri sforzi a lungo termine per aumentare la durata della vita e la durata della salute\u201d, ha spiegato il ricercatore principale, il professor Troy Merry.<\/p>\n<p>&quot;Suggerisce inoltre una serie di possibili modi in cui i trattamenti a breve termine con questo farmaco potrebbero essere utilizzati per trattare determinate condizioni di salute metabolica e stiamo seguendo questo approccio ora&quot;, ha aggiunto Merry.<\/p>\n<p>Il farmaco alpelisib prende di mira un enzima chiamato PI 3-chinasi. Secondo il professor Peter Shepherd, stanno lavorando allo sviluppo di farmaci mirati alla PI 3-chinasi da pi\u00f9 di due decenni. Ci\u00f2 \u00e8 dovuto principalmente al fatto che \u00e8 stato osservato che molti tumori utilizzano un&#039;attivazione eccessiva di questo percorso.<\/p>\n<p>\u201cPertanto, \u00e8 bello vedere che questi farmaci potrebbero avere usi in altri settori e rivelare nuovi meccanismi che contribuiscono alle malattie legate all\u2019et\u00e0. Ci\u00f2 dimostra anche il valore di un investimento a lungo termine nella ricerca in aree come questa\u201d, ha affermato Shepherd, secondo il comunicato.<\/p>\n<p>Un altro studio recente ha scoperto che un\u2019ottima opzione per invertire l\u2019invecchiamento \u00e8 quella di<a href=\"https:\/\/www.medicaldaily.com\/ultrasound-therapy-can-awaken-zombie-cells-and-reverse-aging-study-finds-467818\"> zap cellule \u201czombie\u201d con onde ultrasoniche<\/a>S. Dopo aver sperimentato con successo sui topi pi\u00f9 anziani, i ricercatori stanno ora pianificando una sperimentazione clinica per verificare la sicurezza e l\u2019efficacia della tecnica negli esseri umani. &quot;&#039;\u00c8 troppo bello per essere vero?&#039; \u00e8 la domanda che faccio spesso. Stiamo esaminando tutti gli aspetti per vedere se funziona davvero\u201d, ha detto l\u2019autore principale, il professor Michael Sheetz dell\u2019Universit\u00e0 del Texas.<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/cancer-drug-can-increase-longevity-study-finds-467851?utm_source=Public&#038;utm_medium=Feed&#038;utm_campaign=Distribution\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>&quot;L&#039;invecchiamento non riguarda solo la durata della vita, ma anche la qualit\u00e0 della vita&quot;, ha affermato il ricercatore Dr. Chris Hedges.<\/p>","protected":false},"author":2,"featured_media":7484,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/this-cancer-drug-can-increase-longevity-study-finds.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[150],"class_list":["post-7483","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - 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