{"id":7451,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"lesioni-simmetriche-della-sostanza-bianca-in-un-paziente-con-lupus-eritematoso-sistemico","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/","title":{"rendered":"Lesioni simmetriche della sostanza bianca in un paziente con lupus eritematoso sistemico"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-2\">Una ragazza di 16 anni ha presentato due episodi di mal di testa, dolore al collo e vomito negli ultimi 4 mesi. Nel primo episodio, \u00e8 stata trattata con antibiotici per 5 giorni, dopodich\u00e9 sono stati aggiunti steroidi, poich\u00e9 i suoi sintomi non si sono risolti. Ha avuto un aggravamento dei sintomi quando gli steroidi sono stati diminuiti con un&#039;ulteriore paralisi del retto laterale destro e gonfiore dell&#039;articolazione del ginocchio sinistro. Soffriva di dispnea da sforzo intermittente, eruzioni cutanee fotosensibili sulle guance, perdita di peso, pallore e clubbing. Aveva una potenza di 4\/5 alle articolazioni dell&#039;anca bilaterali. \u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e25?rss=1\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Una ragazza di 16 anni si \u00e8 presentata con due episodi di mal di testa, dolore al collo e vomito negli ultimi 4 mesi. Nel primo episodio, \u00e8 stata trattata con antibiotici per 5 giorni, dopodich\u00e9 sono stati aggiunti steroidi, poich\u00e9 i suoi sintomi non si sono risolti. Ha avuto un aggravamento dei sintomi quando gli steroidi sono stati ridotti gradualmente con ulteriore paralisi del retto laterale destro e gonfiore dell&#039;articolazione del ginocchio sinistro. Presentava dispnea da sforzo intermittente, eruzioni cutanee fotosensibili sulle guance, perdita di peso, pallore e ippocratismo digitale. Aveva 4\/5 di potenza alle articolazioni dell&#039;anca bilaterali.<\/p>\n<p>La risonanza magnetica cerebrale ha mostrato iperintensit\u00e0 T2 confluenti bilateralmente simmetriche nella sostanza bianca periventricolare, sottocorticale e profonda, che \u00e8 stata segnalata come suggestiva di leucodistrofia (<cross-ref type=\"fig\" refid=\"F1\">figura 1A<\/cross-ref>). L&#039;esame del liquido cerebrospinale (CSF) ha mostrato un&#039;alta pressione di 37 mm Hg con cellule nulle e glucosio e proteine normali. La citologia maligna del liquido cerebrospinale era negativa. John Cunningham, il DNA del citomegalovirus e del virus BK nel liquido cerebrospinale non era rilevabile. L&#039;ELISA HIV era negativo.<\/p>\n<p>Bianco simmetrico\u2026<\/p>","protected":false},"author":2,"featured_media":7452,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Symmetrical white matter lesions in a patient with systemic lupus erythematosus - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/lesioni-simmetriche-della-sostanza-bianca-in-un-paziente-con-lupus-eritematoso-sistemico\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 16-year-old girl presented with two episodes of headache, neck pain and vomiting in the last 4 months. In the first episode, she was treated with antibiotics for 5 days following which steroids were added, as her symptoms did not resolve. She had aggravation of symptoms when steroids were tapered with additional right lateral rectus palsy and left knee joint swelling. She had intermittent exertional dyspnoea, photosensitive rashes on cheeks, weight loss, pallor and clubbing. She had 4\/5 power at bilateral hip joints. MRI brain showed confluent bilaterally symmetrical T2 hyperintensities in periventricular, subcortical and deep white matter which was reported to be suggestive of leukodystrophy (figure 1A). Cerebrospinal fluid (CSF) examination showed high pressure of 37 mm Hg with nil cells and normal glucose and protein. CSF malignant cytology was negative. John Cunningham, Cytomegalovirus and BK virus DNA in CSF was not detectable. HIV ELISA was negative. Symmetrical white...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/it\/lesioni-simmetriche-della-sostanza-bianca-in-un-paziente-con-lupus-eritematoso-sistemico\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\"},\"wordCount\":94,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\",\"name\":\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus - 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Symmetrical white...","og_url":"https:\/\/urbancare.clinic\/it\/lesioni-simmetriche-della-sostanza-bianca-in-un-paziente-con-lupus-eritematoso-sistemico\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2022-11-22T10:00:22+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Scritto da":"Urban Care Clinic"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"Symmetrical white matter lesions in a patient with systemic lupus erythematosus","datePublished":"2022-11-22T10:00:22+00:00","mainEntityOfPage":{"@id":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/"},"wordCount":94,"publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"image":{"@id":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg","articleSection":["Research Articles"],"inLanguage":"it-IT"},{"@type":"WebPage","@id":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/","url":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/","name":"Lesioni simmetriche della sostanza bianca in un paziente con lupus eritematoso sistemico - 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