{"id":7302,"date":"2023-01-16T12:39:44","date_gmt":"2023-01-16T09:39:44","guid":{"rendered":"https:\/\/urbancare.clinic\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study\/"},"modified":"2023-01-16T12:39:44","modified_gmt":"2023-01-16T09:39:44","slug":"le-sostanze-chimiche-presenti-nella-vagina-della-mamma-possono-essere-associate-allo-studio-sulla-nascita-pretermine","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study\/","title":{"rendered":"Le sostanze chimiche presenti nella vagina della mamma possono essere associate alla nascita pretermine: studio"},"content":{"rendered":"
<\/div>\n

Le esposizioni ambientali possono colpire le donne incinte? I ricercatori hanno scoperto che le sostanze chimiche presenti nella vagina della madre possono essere associate al parto pretermine spontaneo.<\/p>\n

Per il loro studio, pubblicato<\/a> in Nature Microbiology, un team di ricercatori ha esaminato il metaboloma vaginale del secondo trimestre di 232 donne incinte. Il metaboloma \u00e8 essenzialmente il \u201cset completo<\/a>"delle piccole molecole in una cellula o organismo.<\/p>\n

"Il metaboloma pu\u00f2 essere visto come una lettura funzionale dell'ecosistema nel suo insieme", ha spiegato il co-responsabile dello studio, Tal Korem dell'Irving Medical Center della Columbia University (CIUMC). spiegato<\/a> nella release universitaria. \u201cLa profilazione del microbioma pu\u00f2 dirci chi sono i microbi; la metabolomica ci avvicina alla comprensione di cosa stanno facendo i microbi\u201d.<\/p>\n

Sono stati associati microbi e metaboliti vaginali complicazioni della gravidanza<\/a>, Compreso nascita prematura<\/a> \u2014 la situazione in cui un bambino nasce prima della 37a settimana di gravidanza.<\/p>\n

<\/div>\n

Si ritiene che la nascita pretermine sia la \u201ccausa principale\u201d di morte neonatale, hanno osservato i ricercatori. E anche chi sopravvive potrebbe finire sviluppare problemi<\/a> come problemi respiratori, ritardo dello sviluppo, problemi di udito o paralisi cerebrale.<\/p>\n

La nascita pretermine spontanea (sPTB), d'altro canto, \u00e8 una nascita pretermine che non \u00e8 indotta dal punto di vista medico e rappresenta circa i due terzi di tutti i parto pretermine. Si dice che sia \u201cuna delle principali cause di morbilit\u00e0 e mortalit\u00e0 materna e neonatale\u201d.<\/p>\n

"Precedenti indagini hanno suggerito che i microbi e i metaboliti vaginali potrebbero essere implicati nella sPTB", hanno scritto i ricercatori.<\/p>\n

Tuttavia, un \u201cchiaro consenso\u201d sull\u2019esatta relazione tra i due fattori \u00e8 rimasto in gran parte fuori portata.<\/p>\n

Delle 232 donne coinvolte nello studio, 80 hanno partorito pretermine.<\/p>\n

I ricercatori hanno trovato \u201cassociazioni multiple\u201d tra i metaboliti vaginali delle mamme e l'eventuale parto pretermine. Secondo CUIMC, i metaboliti multipli erano in realt\u00e0 pi\u00f9 alti rispetto a quelli che hanno partorito a termine. In particolare, diversi metaboliti \u201ccon forti associazioni con sPTB\u201d erano esogeni o provenienti da fonti esterne.<\/p>\n

\u201cQuesti includono la dietanolamina (DEA), l\u2019etil-beta glucoside, il tartrato e l\u2019acido etilendiamminotetraacetico\u201d, ha affermato Korem, secondo CUIMC. \u201cAnche se non abbiamo identificato la fonte di questi xenobiotici nei nostri partecipanti, \u00e8 stato possibile trovarli tutti nei cosmetici e nei prodotti per l\u2019igiene\u201d.<\/p>\n

Ad esempio, la DEA non ha \u201cnessuna fonte naturale conosciuta\u201d e si dice che le donne in et\u00e0 riproduttiva siano \u201caltamente esposte\u201d ad essa. L'etilglucoside, invece, si trova nei prodotti che contengono alcol. Si dice che entrambi siano \u201cprecursori o ingredienti di prodotti igienici e cosmetici\u201d.<\/p>\n

"Il fatto che tutti siano documentati nei prodotti igienici e cosmetici solleva la preoccupazione che alcuni di questi prodotti possano aumentare il rischio di sPTB", hanno scritto i ricercatori. \u201cI nostri risultati coincidono con studi recenti che sollevano preoccupazioni riguardo alle esposizioni ambientali durante la gravidanza e identificano queste sostanze chimiche nel tratto riproduttivo\u201d.<\/p>\n

I ricercatori hanno anche sviluppato un algoritmo in grado di prevedere la nascita pretermine \u201ccon buona precisione\u201d. Tuttavia, secondo CUIMC, deve ancora essere migliorato e validato ulteriormente prima di poter essere utilizzato in ambito clinico.<\/p>\n

Nel complesso, i ricercatori hanno dimostrato il potenziale di tali test sui metaboliti nel predire la sPTB e hanno anche evidenziato alcune potenziali esposizioni esterne che potrebbero costituirne fattori di rischio. Varrebbe la pena approfondire la possibile fonte delle esposizioni e se effettivamente causino nascite premature, ha detto Korem.<\/p>\n

\u201cLa buona notizia \u00e8 che se la colpa \u00e8 di queste sostanze chimiche, potrebbe essere possibile limitare queste esposizioni potenzialmente dannose\u201d, ha aggiunto.<\/p>\n

Fonte quotidiana medica<\/a><\/p>\n

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I microbi e i metaboliti vaginali sono stati associati a complicazioni della gravidanza, inclusa la nascita pretermine, la situazione in cui un bambino nasce prima della 37a settimana di gravidanza.<\/p>","protected":false},"author":2,"featured_media":7303,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-7302","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nChemicals In Mom's Vagina May Be Associated With Preterm Birth: Study - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/it\/le-sostanze-chimiche-presenti-nella-vagina-della-mamma-possono-essere-associate-allo-studio-sulla-nascita-pretermine\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemicals In Mom's Vagina May Be Associated With Preterm Birth: Study - 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