{"id":7204,"date":"2023-01-05T06:00:00","date_gmt":"2023-01-05T03:00:00","guid":{"rendered":"https:\/\/www.medicaldaily.com\/scientists-develop-vaccine-brain-cancer-467694"},"modified":"2023-05-23T17:38:31","modified_gmt":"2023-05-23T14:38:31","slug":"gli-scienziati-sviluppano-un-vaccino-per-il-cancro-al-cervello","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/it\/scientists-develop-vaccine-for-brain-cancer\/","title":{"rendered":"Gli scienziati sviluppano un vaccino per il cancro al cervello"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/scientists-develop-vaccine-for-brain-cancer.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>Gli scienziati stanno lavorando su un nuovo vaccino che potrebbe prevenire e contemporaneamente uccidere il cancro al cervello.&nbsp;<\/p>\n<p>Il team sta sfruttando un nuovo mezzo per trasformare le cellule tumorali in agenti antitumorali che potrebbero eliminare i tumori e addestrare il sistema immunitario a prevenire la recidiva del cancro.&nbsp;<\/p>\n<p>Lo sforzo \u00e8 effettuato nel laboratorio di Khalid Shah, MS, Ph.D. al Brigham and Women\u2019s Hospital, con i ricercatori desiderosi di sviluppare un vaccino contro il cancro che produca un\u2019immunit\u00e0 a lungo termine contro la condizione.&nbsp;<\/p>\n<p>Nel loro studio pubblicato su <a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abo4778\" rel=\"nofollow noopener\" target=\"_blank\">Medicina traslazionale scientifica<\/a> mercoled\u00ec, i ricercatori hanno spiegato perch\u00e9 stanno utilizzando cellule tumorali vive invece di cellule tumorali inattivate. Secondo loro, quest\u2019ultimo ha una capacit\u00e0 limitata di uccidere le cellule tumorali prima di indurre una risposta immunitaria. D\u2019altra parte, le cellule tumorali viventi possono tracciare e colpire i tumori.&nbsp;<\/p>\n<div id=\"dfp-ad-oop2\" class=\"dfp-tag-wrapper\"> <\/div>\n<p>Per lo studio, hanno ingegnerizzato cellule tumorali terapeutiche e le hanno utilizzate per eliminare i tumori del glioblastoma nei topi. Il glioblastoma \u00e8 un tipo di tumore a crescita rapida nel sistema nervoso centrale, che si forma dal tessuto di supporto del cervello e del midollo spinale, secondo il <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/glioblastoma\" rel=\"nofollow noopener\" target=\"_blank\">Istituto Nazionale Tumori<\/a>.&nbsp;<\/p>\n<p>Le cellule tumorali terapeutiche non solo hanno eliminato i tumori, ma si sono anche tradotte in un beneficio di sopravvivenza e in un\u2019immunit\u00e0 a lungo termine negli esperimenti sui topi umanizzati. Il team ha definito ci\u00f2 che hanno sviluppato \u201cuna promettente immunoterapia basata sulle cellule per i tumori solidi\u201d.<\/p>\n<p>&quot;Il nostro team ha perseguito un&#039;idea semplice: prendere le cellule tumorali e trasformarle in farmaci antitumorali e vaccini&quot;, ha detto Shah, l&#039;autore corrispondente dello studio, in una conferenza stampa. <a href=\"https:\/\/www.eurekalert.org\/news-releases\/975452\" rel=\"nofollow noopener\" target=\"_blank\">comunicato stampa<\/a>.&nbsp;<\/p>\n<p>Il vicepresidente della ricerca presso il Dipartimento di Neurochirurgia del Brigham ha continuato: \u201cUtilizzando l\u2019ingegneria genetica, stiamo riproponendo le cellule tumorali per sviluppare una terapia che uccida le cellule tumorali e stimoli il sistema immunitario sia a distruggere i tumori primari che a prevenire il cancro\u201d.<\/p>\n<p>Shah ha osservato che il loro obiettivo era quello di sviluppare un \u201cvaccino antitumorale\u201d che avrebbe un grande impatto sulla comunit\u00e0 medica. Tuttavia, sono ancora necessarie ulteriori ricerche per comprenderne appieno le applicazioni.&nbsp;<\/p>\n<p>\u201cDurante tutto il lavoro che svolgiamo nel Centro, anche quando \u00e8 altamente tecnico, non perdiamo mai di vista il paziente. Il nostro obiettivo \u00e8 adottare un approccio innovativo ma traducibile in modo da poter sviluppare un vaccino terapeutico che uccide il cancro e che alla fine avr\u00e0 un impatto duraturo in medicina\u201d, ha affermato.&nbsp;<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/scientists-develop-vaccine-brain-cancer-467694?utm_source=Public&#038;utm_medium=Feed&#038;utm_campaign=Distribution\">Fonte quotidiana medica<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Il vaccino potrebbe eliminare i tumori e prevenire le recidive del cancro.<\/p>","protected":false},"author":2,"featured_media":7205,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/scientists-develop-vaccine-for-brain-cancer.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[150],"class_list":["post-7204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - 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