{"id":9151,"date":"2023-12-07T11:54:53","date_gmt":"2023-12-07T08:54:53","guid":{"rendered":"https:\/\/urbancare.simplyit.solutions\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"modified":"2023-12-07T11:54:53","modified_gmt":"2023-12-07T08:54:53","slug":"les-personnes-de-plus-de-50-ans-peuvent-avoir-un-vieillissement-accelere-dans-au-moins-1-organe-un-test-sanguin-pourrait-le-detecter","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/","title":{"rendered":"Les personnes de plus de 50 ans peuvent avoir un vieillissement acc\u00e9l\u00e9r\u00e9 dans au moins 1 organe\u00a0; Un test sanguin pourrait le d\u00e9tecter"},"content":{"rendered":"
<\/div>\n

Chaque organe de notre corps vieillit \u00e0 un rythme diff\u00e9rent. Les chercheurs affirment d\u00e9sormais qu'environ 18% chez les adultes en bonne sant\u00e9 de plus de 50 ans sont confront\u00e9s \u00e0 un vieillissement acc\u00e9l\u00e9r\u00e9 dans au moins un de leurs organes.<\/p>\n

UN \u00e9tude<\/a>, dirig\u00e9 par des chercheurs de Stanford Medicine, sugg\u00e8re qu'avec un simple test sanguin, il pourrait \u00eatre possible de d\u00e9tecter le vieillissement acc\u00e9l\u00e9r\u00e9 d'un organe qui augmente le risque de maladie et la mortalit\u00e9.<\/p>\n

\u00ab On peut estimer l\u2019\u00e2ge biologique d\u2019un organe chez une personne apparemment en bonne sant\u00e9. Cela, \u00e0 son tour, pr\u00e9dit le risque de maladie li\u00e9e \u00e0 cet organe. a dit<\/a> l'auteur principal de l'\u00e9tude, Tony Wyss-Coray.<\/p>\n

"De nombreuses \u00e9tudes ont abouti \u00e0 des chiffres uniques repr\u00e9sentant l'\u00e2ge biologique des individus - l'\u00e2ge impliqu\u00e9 par un ensemble sophistiqu\u00e9 de biomarqueurs - par opposition \u00e0 leur \u00e2ge chronique, le nombre r\u00e9el d'ann\u00e9es \u00e9coul\u00e9es depuis leur naissance", a d\u00e9clar\u00e9 Wyss-Coray.<\/p>\n

Cependant, l\u2019\u00e9quipe est all\u00e9e plus loin en identifiant l\u2019\u00e2ge biologique de chacun des 11 organes et syst\u00e8mes organiques cl\u00e9s : c\u0153ur, graisse, poumon, syst\u00e8me immunitaire, rein, foie, muscle, pancr\u00e9as, cerveau, syst\u00e8me vasculaire et intestin.<\/p>\n

"Lorsque nous avons compar\u00e9 l'\u00e2ge biologique de chacun de ces organes pour chaque individu avec ses homologues parmi un grand groupe de personnes sans maladies graves \u00e9videntes, nous avons constat\u00e9 que 18,41 TP3T parmi les personnes \u00e2g\u00e9es de 50 ans ou plus avaient au moins un organe vieillissant significativement plus rapidement que le moyenne \u00bb, a d\u00e9clar\u00e9 Wyss-Coray.<\/p>\n

L'\u00e9tude a \u00e9valu\u00e9 5 678 participants. Les r\u00e9sultats ont montr\u00e9 que seulement 1 participant sur 60 avait deux organes vieillissant \u00e0 un rythme acc\u00e9l\u00e9r\u00e9. Le vieillissement acc\u00e9l\u00e9r\u00e9 de deux organes augmente le risque de mortalit\u00e9 de 6,5 fois.<\/p>\n

"En utilisant des technologies disponibles dans le commerce et un algorithme de leur propre conception, les chercheurs ont \u00e9valu\u00e9 les niveaux de milliers de prot\u00e9ines dans le sang des personnes, ont d\u00e9termin\u00e9 que pr\u00e8s de 1 000 de ces prot\u00e9ines provenaient de l'un ou l'autre organe et ont li\u00e9 les niveaux aberrants de ces prot\u00e9ines aux niveaux correspondants. vieillissement acc\u00e9l\u00e9r\u00e9 des organes et susceptibilit\u00e9 aux maladies et \u00e0 la mortalit\u00e9 \u00bb, ont expliqu\u00e9 les chercheurs.<\/p>\n

L\u2019\u00e9quipe de recherche a estim\u00e9 un \u00ab\u00a0\u00e9cart d\u2019\u00e2ge\u00a0\u00bb pour chaque organe. L'\u00e9cart d'\u00e2ge fait r\u00e9f\u00e9rence \u00e0 la diff\u00e9rence entre l'\u00e2ge r\u00e9el d'un organe et l'\u00e2ge estim\u00e9 sur la base des calculs de l'algorithme bas\u00e9s sur les prot\u00e9ines sp\u00e9cifiques \u00e0 un organe. Les \u00e9carts d\u2019\u00e2ge identifi\u00e9s, \u00e0 l\u2019exception de celui de l\u2019intestin, \u00e9taient significativement associ\u00e9s au risque futur de d\u00e9c\u00e8s toutes causes confondues.<\/p>\n

Avoir un organe vieillissant acc\u00e9l\u00e9r\u00e9 augmente le risque de mortalit\u00e9 de 15% \u00e0 50% au cours des 15 prochaines ann\u00e9es, ont indiqu\u00e9 les chercheurs. Le risque de mortalit\u00e9 d\u00e9pend de l'organe touch\u00e9.<\/p>\n

Alors que le vieillissement cardiaque acc\u00e9l\u00e9r\u00e9 augmente le risque d\u2019insuffisance cardiaque de 2,5 fois, le vieillissement c\u00e9r\u00e9bral augmente de 1,8 fois le risque de d\u00e9clin cognitif.<\/p>\n

Les chercheurs affirment que si cela est v\u00e9rifi\u00e9 sur une population plus large, cela pourrait aider \u00e0 pr\u00e9dire la d\u00e9faillance d\u2019un organe et le risque de maladie avant m\u00eame l\u2019apparition des sympt\u00f4mes.<\/p>\n

"Si nous pouvons reproduire cette d\u00e9couverte chez 50 000 ou 100 000 individus, cela signifiera qu'en surveillant la sant\u00e9 d'organes individuels chez des personnes apparemment en bonne sant\u00e9, nous pourrons peut-\u00eatre trouver des organes qui subissent un vieillissement acc\u00e9l\u00e9r\u00e9 dans le corps des gens, et nous pourrons peut-\u00eatre traiter les gens avant qu\u2019ils ne tombent malades \u00bb, a d\u00e9clar\u00e9 Wyss-Coray.<\/p>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Chaque organe de notre corps vieillit \u00e0 un rythme diff\u00e9rent. Les chercheurs affirment d\u00e9sormais qu'environ 18% chez les adultes en bonne sant\u00e9 de plus de 50 ans sont confront\u00e9s \u00e0 un vieillissement acc\u00e9l\u00e9r\u00e9 dans au moins un de leurs organes.<\/p>\n

UN \u00e9tude<\/a>, dirig\u00e9 par des chercheurs de Stanford Medicine, sugg\u00e8re qu'avec un simple test sanguin, il pourrait \u00eatre possible de d\u00e9tecter le vieillissement acc\u00e9l\u00e9r\u00e9 d'un organe qui augmente le risque de maladie et la mortalit\u00e9.<\/p>\n

\u00ab On peut estimer l\u2019\u00e2ge biologique d\u2019un organe chez une personne apparemment en bonne sant\u00e9. Cela, \u00e0 son tour, pr\u00e9dit le risque de maladie li\u00e9e \u00e0 cet organe. a dit<\/a> l'auteur principal de l'\u00e9tude, Tony Wyss-Coray.<\/p>\n

"De nombreuses \u00e9tudes ont abouti \u00e0 des chiffres uniques repr\u00e9sentant l'\u00e2ge biologique des individus - l'\u00e2ge impliqu\u00e9 par un ensemble sophistiqu\u00e9 de biomarqueurs - par opposition \u00e0 leur \u00e2ge chronique, le nombre r\u00e9el d'ann\u00e9es \u00e9coul\u00e9es depuis leur naissance", a d\u00e9clar\u00e9 Wyss-Coray.<\/p>\n

Cependant, l\u2019\u00e9quipe est all\u00e9e plus loin en identifiant l\u2019\u00e2ge biologique de chacun des 11 organes et syst\u00e8mes organiques cl\u00e9s : c\u0153ur, graisse, poumon, syst\u00e8me immunitaire, rein, foie, muscle, pancr\u00e9as, cerveau, syst\u00e8me vasculaire et intestin.<\/p>\n

"Lorsque nous avons compar\u00e9 l'\u00e2ge biologique de chacun de ces organes pour chaque individu avec ses homologues parmi un grand groupe de personnes sans maladies graves \u00e9videntes, nous avons constat\u00e9 que 18,41 TP3T parmi les personnes \u00e2g\u00e9es de 50 ans ou plus avaient au moins un organe vieillissant significativement plus rapidement que le moyenne \u00bb, a d\u00e9clar\u00e9 Wyss-Coray.<\/p>\n

L'\u00e9tude a \u00e9valu\u00e9 5 678 participants. Les r\u00e9sultats ont montr\u00e9 que seulement 1 participant sur 60 avait deux organes vieillissant \u00e0 un rythme acc\u00e9l\u00e9r\u00e9. Le vieillissement acc\u00e9l\u00e9r\u00e9 de deux organes augmente le risque de mortalit\u00e9 de 6,5 fois.<\/p>\n

"En utilisant des technologies disponibles dans le commerce et un algorithme de leur propre conception, les chercheurs ont \u00e9valu\u00e9 les niveaux de milliers de prot\u00e9ines dans le sang des personnes, ont d\u00e9termin\u00e9 que pr\u00e8s de 1 000 de ces prot\u00e9ines provenaient de l'un ou l'autre organe et ont li\u00e9 les niveaux aberrants de ces prot\u00e9ines aux niveaux correspondants. vieillissement acc\u00e9l\u00e9r\u00e9 des organes et susceptibilit\u00e9 aux maladies et \u00e0 la mortalit\u00e9 \u00bb, ont expliqu\u00e9 les chercheurs.<\/p>\n

L\u2019\u00e9quipe de recherche a estim\u00e9 un \u00ab\u00a0\u00e9cart d\u2019\u00e2ge\u00a0\u00bb pour chaque organe. L'\u00e9cart d'\u00e2ge fait r\u00e9f\u00e9rence \u00e0 la diff\u00e9rence entre l'\u00e2ge r\u00e9el d'un organe et l'\u00e2ge estim\u00e9 sur la base des calculs de l'algorithme bas\u00e9s sur les prot\u00e9ines sp\u00e9cifiques \u00e0 un organe. Les \u00e9carts d\u2019\u00e2ge identifi\u00e9s, \u00e0 l\u2019exception de celui de l\u2019intestin, \u00e9taient significativement associ\u00e9s au risque futur de d\u00e9c\u00e8s toutes causes confondues.<\/p>\n

Avoir un organe vieillissant acc\u00e9l\u00e9r\u00e9 augmente le risque de mortalit\u00e9 de 15% \u00e0 50% au cours des 15 prochaines ann\u00e9es, ont indiqu\u00e9 les chercheurs. Le risque de mortalit\u00e9 d\u00e9pend de l'organe touch\u00e9.<\/p>\n

Alors que le vieillissement cardiaque acc\u00e9l\u00e9r\u00e9 augmente le risque d\u2019insuffisance cardiaque de 2,5 fois, le vieillissement c\u00e9r\u00e9bral augmente de 1,8 fois le risque de d\u00e9clin cognitif.<\/p>\n

Les chercheurs affirment que si cela est v\u00e9rifi\u00e9 sur une population plus large, cela pourrait aider \u00e0 pr\u00e9dire la d\u00e9faillance d\u2019un organe et le risque de maladie avant m\u00eame l\u2019apparition des sympt\u00f4mes.<\/p>\n

"Si nous pouvons reproduire cette d\u00e9couverte chez 50 000 ou 100 000 individus, cela signifiera qu'en surveillant la sant\u00e9 d'organes individuels chez des personnes apparemment en bonne sant\u00e9, nous pourrons peut-\u00eatre trouver des organes qui subissent un vieillissement acc\u00e9l\u00e9r\u00e9 dans le corps des gens, et nous pourrons peut-\u00eatre traiter les gens avant qu\u2019ils ne tombent malades \u00bb, a d\u00e9clar\u00e9 Wyss-Coray.<\/p>","protected":false},"author":2,"featured_media":9152,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9151","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nPeople Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/les-personnes-de-plus-de-50-ans-peuvent-avoir-un-vieillissement-accelere-dans-au-moins-1-organe-un-test-sanguin-pourrait-le-detecter\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality."We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person's risk for disease related to that organ," said the study's senior author, Tony Wyss-Coray."Numerous studies have come up with single numbers representing individuals' biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth," Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine."When we compared each of these organs' biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average," Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times."Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people's blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs' accelerated aging and susceptibility to disease and mortality," the researchers explained.The research team estimated an "age gap" for each organ. Age gap refers to the difference between an organ's actual age and the age estimated based on the algorithm's organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear."If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people's bodies, and we might be able to treat people before they get sick," Wyss-Coray said.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/les-personnes-de-plus-de-50-ans-peuvent-avoir-un-vieillissement-accelere-dans-au-moins-1-organe-un-test-sanguin-pourrait-le-detecter\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-07T08:54:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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Un test sanguin pourrait le d\u00e9tecter - Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/fr\/les-personnes-de-plus-de-50-ans-peuvent-avoir-un-vieillissement-accelere-dans-au-moins-1-organe-un-test-sanguin-pourrait-le-detecter\/","og_locale":"fr_FR","og_type":"article","og_title":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic","og_description":"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality.\"We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person's risk for disease related to that organ,\" said the study's senior author, Tony Wyss-Coray.\"Numerous studies have come up with single numbers representing individuals' biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth,\" Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine.\"When we compared each of these organs' biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average,\" Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times.\"Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people's blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs' accelerated aging and susceptibility to disease and mortality,\" the researchers explained.The research team estimated an \"age gap\" for each organ. Age gap refers to the difference between an organ's actual age and the age estimated based on the algorithm's organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear.\"If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people's bodies, and we might be able to treat people before they get sick,\" Wyss-Coray said.","og_url":"https:\/\/urbancare.clinic\/fr\/les-personnes-de-plus-de-50-ans-peuvent-avoir-un-vieillissement-accelere-dans-au-moins-1-organe-un-test-sanguin-pourrait-le-detecter\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-12-07T08:54:53+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Urban Care Clinic","Dur\u00e9e de lecture estim\u00e9e":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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