{"id":8631,"date":"2023-09-08T10:17:04","date_gmt":"2023-09-08T07:17:04","guid":{"rendered":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/"},"modified":"2023-09-08T10:17:04","modified_gmt":"2023-09-08T07:17:04","slug":"une-etude-sur-le-cancer-du-sein-et-la-grossesse-explique-pourquoi-les-meres-plus-agees-pour-la-premiere-fois-courent-un-risque-plus-eleve","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/une-etude-sur-le-cancer-du-sein-et-la-grossesse-explique-pourquoi-les-meres-plus-agees-pour-la-premiere-fois-courent-un-risque-plus-eleve\/","title":{"rendered":"Cancer du sein et grossesse\u00a0: une \u00e9tude explique pourquoi les m\u00e8res plus \u00e2g\u00e9es pour la premi\u00e8re fois courent un risque plus \u00e9lev\u00e9"},"content":{"rendered":"
<\/div>\n

Il existe un lien complexe entre le cancer du sein et la grossesse. Dans une \u00e9tude, des chercheurs expliquent pourquoi les femmes qui deviennent m\u00e8res pour la premi\u00e8re fois plus tard dans la vie courent un risque \u00e0 long terme plus \u00e9lev\u00e9 de cancer du sein que celles qui deviennent m\u00e8res t\u00f4t.<\/p>\n

Des \u00e9tudes montrent que les jeunes m\u00e8res pour la premi\u00e8re fois, c'est-\u00e0-dire celles qui ont moins de 24 ans lors de leur premi\u00e8re grossesse, courent un risque \u00e0 long terme nettement inf\u00e9rieur de cancer du sein<\/a> (environ 20-35%) par rapport aux femmes qui n'ont pas eu d'enfants.<\/p>\n

Cependant, \u00e0 mesure que l\u2019\u00e2ge des m\u00e8res pour la premi\u00e8re fois augmente, le risque de cancer du sein augmente \u00e9galement progressivement, avec un pic de risque 5% tous les cinq ans.<\/p>\n

\u00ab Au cours des derni\u00e8res d\u00e9cennies, les femmes ont commenc\u00e9 \u00e0 avoir des enfants plus tard en raison de changements soci\u00e9taux et de pr\u00e9f\u00e9rences personnelles. Des recherches ant\u00e9rieures ont montr\u00e9 que cela est associ\u00e9 \u00e0 un risque accru de cancer du sein \u00bb, a d\u00e9clar\u00e9 le Dr Biancastella Cereser, auteur principal de l'\u00e9tude, dans le communiqu\u00e9 de presse.<\/p>\n

\u00ab Nos propres recherches approfondissent les myst\u00e8res g\u00e9n\u00e9tiques qui r\u00e9gissent ce risque. Nous avons constat\u00e9 que le sein humain, comme d'autres organes, accumule des mutations avec l'\u00e2ge, mais aussi que la grossesse a un effet suppl\u00e9mentaire, ce qui signifie que les m\u00e8res plus \u00e2g\u00e9es pour la premi\u00e8re fois pourraient avoir un risque plus \u00e9lev\u00e9 de d\u00e9velopper des changements nocifs dans leurs cellules mammaires par rapport aux autres femmes. ", a d\u00e9clar\u00e9 Cereser.<\/p>\n

Dans la derni\u00e8re \u00e9tude, publi\u00e9e dans le journal<\/a> Nature Communications, les chercheurs ont analys\u00e9 les changements cellulaires et g\u00e9n\u00e9tiques qui se produisent dans les cellules mammaires saines au fur et \u00e0 mesure de leur transformation. canc\u00e9reux<\/a>. Apr\u00e8s avoir s\u00e9quenc\u00e9 29 tissus mammaires sains congel\u00e9s provenant de donneurs, l\u2019\u00e9quipe a constat\u00e9 qu\u2019avec l\u2019\u00e2ge, ces tissus mammaires sains accumulent des mutations, au rythme d\u2019environ 15 mutations chaque ann\u00e9e. Bien que la majorit\u00e9 de ces mutations n\u2019affectent pas les g\u00e8nes et ne provoquent pas de cancer, avec plus de temps, il y a un plus grand risque d\u2019avoir des mutations motrices associ\u00e9es au cancer.<\/p>\n

\u00ab Cela pourrait ne pas suffire \u00e0 lui seul \u00e0 provoquer le cancer. Mais la grossesse pourrait constituer un \u00ab double coup dur \u00bb, car elle induit une expansion rapide des cellules mammaires, en pr\u00e9paration \u00e0 l\u2019allaitement. Si les cellules h\u00e9bergeant des mutations motrices se r\u00e9pliquent et se d\u00e9veloppent, elles pourraient avoir un avantage comp\u00e9titif sur les cellules voisines non mut\u00e9es, conduisant potentiellement \u00e0 un effet d\u2019emballement et, \u00e0 terme, cr\u00e9ant une tumeur canc\u00e9reuse \u00bb, a expliqu\u00e9 Cereser.<\/p>\n

Publi\u00e9 par Medicaldaily.com<\/p>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Il existe un lien complexe entre le cancer du sein et la grossesse. Dans une \u00e9tude, des chercheurs expliquent pourquoi les femmes qui deviennent m\u00e8res pour la premi\u00e8re fois plus tard dans la vie courent un risque \u00e0 long terme plus \u00e9lev\u00e9 de cancer du sein que celles qui deviennent m\u00e8res t\u00f4t.<\/p>\n

Des \u00e9tudes montrent que les jeunes m\u00e8res pour la premi\u00e8re fois, c'est-\u00e0-dire celles qui ont moins de 24 ans lors de leur premi\u00e8re grossesse, courent un risque \u00e0 long terme nettement inf\u00e9rieur de cancer du sein<\/a> (environ 20-35%) par rapport aux femmes qui n'ont pas eu d'enfants.<\/p>\n

Cependant, \u00e0 mesure que l\u2019\u00e2ge des m\u00e8res pour la premi\u00e8re fois augmente, le risque de cancer du sein augmente \u00e9galement progressivement, avec un pic de risque 5% tous les cinq ans.<\/p>\n

\u00ab Au cours des derni\u00e8res d\u00e9cennies, les femmes ont commenc\u00e9 \u00e0 avoir des enfants plus tard en raison de changements soci\u00e9taux et de pr\u00e9f\u00e9rences personnelles. Des recherches ant\u00e9rieures ont montr\u00e9 que cela est associ\u00e9 \u00e0 un risque accru de cancer du sein \u00bb, a d\u00e9clar\u00e9 le Dr Biancastella Cereser, auteur principal de l'\u00e9tude, dans le communiqu\u00e9 de presse.<\/p>\n

\u00ab Nos propres recherches approfondissent les myst\u00e8res g\u00e9n\u00e9tiques qui r\u00e9gissent ce risque. Nous avons constat\u00e9 que le sein humain, comme d'autres organes, accumule des mutations avec l'\u00e2ge, mais aussi que la grossesse a un effet suppl\u00e9mentaire, ce qui signifie que les m\u00e8res plus \u00e2g\u00e9es pour la premi\u00e8re fois pourraient avoir un risque plus \u00e9lev\u00e9 de d\u00e9velopper des changements nocifs dans leurs cellules mammaires par rapport aux autres femmes. ", a d\u00e9clar\u00e9 Cereser.<\/p>\n

Dans la derni\u00e8re \u00e9tude, publi\u00e9e dans le journal<\/a> Nature Communications, les chercheurs ont analys\u00e9 les changements cellulaires et g\u00e9n\u00e9tiques qui se produisent dans les cellules mammaires saines au fur et \u00e0 mesure de leur transformation. canc\u00e9reux<\/a>. Apr\u00e8s avoir s\u00e9quenc\u00e9 29 tissus mammaires sains congel\u00e9s provenant de donneurs, l\u2019\u00e9quipe a constat\u00e9 qu\u2019avec l\u2019\u00e2ge, ces tissus mammaires sains accumulent des mutations, au rythme d\u2019environ 15 mutations chaque ann\u00e9e. Bien que la majorit\u00e9 de ces mutations n\u2019affectent pas les g\u00e8nes et ne provoquent pas de cancer, avec plus de temps, il y a un plus grand risque d\u2019avoir des mutations motrices associ\u00e9es au cancer.<\/p>\n

\u00ab Cela pourrait ne pas suffire \u00e0 lui seul \u00e0 provoquer le cancer. Mais la grossesse pourrait constituer un \u00ab double coup dur \u00bb, car elle induit une expansion rapide des cellules mammaires, en pr\u00e9paration \u00e0 l\u2019allaitement. Si les cellules h\u00e9bergeant des mutations motrices se r\u00e9pliquent et se d\u00e9veloppent, elles pourraient avoir un avantage comp\u00e9titif sur les cellules voisines non mut\u00e9es, conduisant potentiellement \u00e0 un effet d\u2019emballement et, \u00e0 terme, cr\u00e9ant une tumeur canc\u00e9reuse \u00bb, a expliqu\u00e9 Cereser.<\/p>\n

Publi\u00e9 par Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8632,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8631","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nBreast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/une-etude-sur-le-cancer-du-sein-et-la-grossesse-explique-pourquoi-les-meres-plus-agees-pour-la-premiere-fois-courent-un-risque-plus-eleve\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Breast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"There is an intricate connection between breast cancer and pregnancy. In a study, researchers explain why women who become first-time mothers later in life have a higher long-term risk of breast cancer than those who become moms early.Studies show that young first-time mothers, those who are below the age of 24 during their initial pregnancy, experience a substantially lower long-term risk of breast cancer (approximately 20-35%) compared to women who have not had kids.However, as the age of first-time mothers goes up, the breast cancer risk also progressively increases, with a 5% spike in risk every five years."In recent decades, women have begun having children later because of societal changes and personal preferences. Previous research has found that this is associated with a heightened breast cancer risk," Dr. Biancastella Cereser, a lead author of the study, said in the news release."Our own research delves into the genetic mysteries that govern this risk. We found that the human breast, like other organs, accumulates mutations with age, but also that pregnancy has an additional effect, meaning that older first-time mothers might have a higher chance of developing harmful changes in their breast cells compared to other women," Cereser said.In the latest study, published in the journal Nature Communications, researchers analyzed the cellular and genetic changes that happen to healthy breast cells as they turn cancerous. After sequencing 29 frozen healthy breast tissues from donors, the team found that with age, these healthy breast tissues accumulate mutations, at the rate of around 15 mutations every year. Although the majority of these mutations do not affect the genes and are not cancer-causing, with more time, there is a greater chance of having driver mutations associated with cancer."This might not be enough to cause cancer by itself. But, pregnancy could provide a 'double whammy', because it induces a rapid expansion of breast cells, in preparation for breastfeeding. 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Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/fr\/une-etude-sur-le-cancer-du-sein-et-la-grossesse-explique-pourquoi-les-meres-plus-agees-pour-la-premiere-fois-courent-un-risque-plus-eleve\/","og_locale":"fr_FR","og_type":"article","og_title":"Breast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk - Urban Care Clinic","og_description":"There is an intricate connection between breast cancer and pregnancy. In a study, researchers explain why women who become first-time mothers later in life have a higher long-term risk of breast cancer than those who become moms early.Studies show that young first-time mothers, those who are below the age of 24 during their initial pregnancy, experience a substantially lower long-term risk of breast cancer (approximately 20-35%) compared to women who have not had kids.However, as the age of first-time mothers goes up, the breast cancer risk also progressively increases, with a 5% spike in risk every five years.\"In recent decades, women have begun having children later because of societal changes and personal preferences. Previous research has found that this is associated with a heightened breast cancer risk,\" Dr. Biancastella Cereser, a lead author of the study, said in the news release.\"Our own research delves into the genetic mysteries that govern this risk. We found that the human breast, like other organs, accumulates mutations with age, but also that pregnancy has an additional effect, meaning that older first-time mothers might have a higher chance of developing harmful changes in their breast cells compared to other women,\" Cereser said.In the latest study, published in the journal Nature Communications, researchers analyzed the cellular and genetic changes that happen to healthy breast cells as they turn cancerous. After sequencing 29 frozen healthy breast tissues from donors, the team found that with age, these healthy breast tissues accumulate mutations, at the rate of around 15 mutations every year. Although the majority of these mutations do not affect the genes and are not cancer-causing, with more time, there is a greater chance of having driver mutations associated with cancer.\"This might not be enough to cause cancer by itself. But, pregnancy could provide a 'double whammy', because it induces a rapid expansion of breast cells, in preparation for breastfeeding. If cells harboring driver mutations replicate and expand, they could have a competitive advantage over neighboring non-mutated cells, potentially leading to a runaway effect, and ultimately creating a cancerous tumor,\" Cereser explained.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/fr\/une-etude-sur-le-cancer-du-sein-et-la-grossesse-explique-pourquoi-les-meres-plus-agees-pour-la-premiere-fois-courent-un-risque-plus-eleve\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-09-08T07:17:04+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk.jpg","type":"","width":"","height":""}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_image":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk.jpg","twitter_misc":{"\u00c9crit par":"Urban Care Clinic","Dur\u00e9e de lecture estim\u00e9e":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c"},"headline":"Breast Cancer And Pregnancy: Study Explains Why Older First-Time Moms Are At Higher Risk","datePublished":"2023-09-08T07:17:04+00:00","mainEntityOfPage":{"@id":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/"},"wordCount":367,"publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"image":{"@id":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/09\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk.jpg","articleSection":["Medical Daily"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/","url":"https:\/\/urbancare.clinic\/breast-cancer-and-pregnancy-study-explains-why-older-first-time-moms-are-at-higher-risk\/","name":"Cancer du sein et grossesse\u00a0: une \u00e9tude explique pourquoi les m\u00e8res plus \u00e2g\u00e9es pour la premi\u00e8re fois courent un risque plus \u00e9lev\u00e9 - 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