{"id":8588,"date":"2023-08-18T10:54:45","date_gmt":"2023-08-18T07:54:45","guid":{"rendered":"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/"},"modified":"2023-08-18T10:54:45","modified_gmt":"2023-08-18T07:54:45","slug":"un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses\/","title":{"rendered":"Un m\u00e9dicament prescrit pour la perte de poids pourrait aider \u00e0 am\u00e9liorer l'apprentissage associatif chez les personnes ob\u00e8ses"},"content":{"rendered":"
<\/div>\n

Selon une \u00e9tude r\u00e9cente, un m\u00e9dicament prescrit pour la perte de poids et le diab\u00e8te de type 2 pourrait am\u00e9liorer l'apprentissage associatif chez les personnes ob\u00e8ses.<\/p>\n

L'apprentissage associatif est le processus par lequel les \u00eatres vivants apprennent Connexions<\/a> entre les choses qui se passent autour d'eux. Elle implique \u00e0 la fois des modifications de comportements existants et le d\u00e9veloppement de nouveaux comportements.<\/p>\n

Des chercheurs de l'Institut Max Planck pour la recherche sur le m\u00e9tabolisme ont \u00e9valu\u00e9 comment l'apprentissage associatif change chez les personnes pr\u00e9sentant une sensibilit\u00e9 alt\u00e9r\u00e9e \u00e0 l'insuline associ\u00e9e \u00e0 l'ob\u00e9sit\u00e9. Ils ont \u00e9tudi\u00e9 les comportements d'apprentissage associ\u00e9s dans deux groupes de participants; l'un avec un poids normal, qui avait une sensibilit\u00e9 \u00e9lev\u00e9e \u00e0 l'insuline, et l'autre avec une sensibilit\u00e9 r\u00e9duite \u00e0 l'insuline due \u00e0 l'ob\u00e9sit\u00e9. L'\u00e9quipe a d\u00e9couvert que la r\u00e9duction de la sensibilit\u00e9 \u00e0 l'insuline due \u00e0 l'ob\u00e9sit\u00e9 alt\u00e8re l'apprentissage associatif.<\/p>\n

Les participants du groupe ob\u00e8se ont re\u00e7u soit un placebo, soit du liraglutide \u2013 un medicament pour maigrir<\/a> prescrit pour l'ob\u00e9sit\u00e9 et le diab\u00e8te de type 2.<\/p>\n

Avec une seule dose de liraglutide, l'apprentissage associatif alt\u00e9r\u00e9 chez les personnes ob\u00e8ses peut \u00eatre invers\u00e9 et ramen\u00e9 au m\u00eame niveau que celui des personnes de poids normal, selon les r\u00e9sultats publi\u00e9s dans la revue Nature Metabolism.<\/p>\n

\u00ab Ces d\u00e9couvertes sont d'une importance fondamentale. Nous montrons ici que les comportements de base tels que l'apprentissage associatif d\u00e9pendent non seulement des conditions environnementales externes mais aussi de l'\u00e9tat m\u00e9tabolique du corps. Ainsi, le fait qu'une personne soit en surpoids ou non d\u00e9termine \u00e9galement comment le cerveau apprend \u00e0 associer les signaux sensoriels et quelle motivation est g\u00e9n\u00e9r\u00e9e. La normalisation que nous avons obtenue avec le m\u00e9dicament chez les sujets ob\u00e8ses correspond donc aux \u00e9tudes montrant que ces m\u00e9dicaments r\u00e9tablissent une sensation normale de sati\u00e9t\u00e9, obligeant les gens \u00e0 manger moins et donc \u00e0 perdre du poids \u00bb, a d\u00e9clar\u00e9 le responsable de l'\u00e9tude, Marc Tittgemeyer. communiqu\u00e9 de presse<\/a>.<\/p>\n

L'\u00e9tude montre comment l'ob\u00e9sit\u00e9 peut alt\u00e9rer le cerveau et comment le processus peut \u00eatre modifi\u00e9 avec des m\u00e9dicaments. Les chercheurs pr\u00e9voient de mener d'autres \u00e9tudes pour comprendre le fonctionnement du liraglutide \u00e0 un niveau niveau mol\u00e9culaire<\/a>. Ils pr\u00e9voient \u00e9galement d'explorer si d'autres approches telles que les essais de perte de poids et les sensibilisateurs \u00e0 l'insuline peuvent \u00e9galement apporter des am\u00e9liorations similaires.<\/p>\n

"Bien qu'il soit encourageant que les m\u00e9dicaments disponibles aient un effet positif sur l'activit\u00e9 c\u00e9r\u00e9brale dans l'ob\u00e9sit\u00e9, il est alarmant que des changements dans les performances c\u00e9r\u00e9brales se produisent m\u00eame chez les jeunes ob\u00e8ses sans autres conditions m\u00e9dicales. La pr\u00e9vention de l'ob\u00e9sit\u00e9 devrait jouer un r\u00f4le beaucoup plus important dans notre syst\u00e8me de sant\u00e9 \u00e0 l'avenir. La m\u00e9dication \u00e0 vie est l'option la moins appr\u00e9ci\u00e9e par rapport \u00e0 la pr\u00e9vention primaire de l'ob\u00e9sit\u00e9 et des complications associ\u00e9es \u00bb, a d\u00e9clar\u00e9 Ruth Han\u00dfen, premi\u00e8re auteure de l'\u00e9tude et m\u00e9decin \u00e0 l'h\u00f4pital universitaire de Cologne.<\/p>\n

Publi\u00e9 par Medicaldaily.com<\/p>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Selon une \u00e9tude r\u00e9cente, un m\u00e9dicament prescrit pour la perte de poids et le diab\u00e8te de type 2 pourrait am\u00e9liorer l'apprentissage associatif chez les personnes ob\u00e8ses.<\/p>\n

L'apprentissage associatif est le processus par lequel les \u00eatres vivants apprennent Connexions<\/a> entre les choses qui se passent autour d'eux. Elle implique \u00e0 la fois des modifications de comportements existants et le d\u00e9veloppement de nouveaux comportements.<\/p>\n

Des chercheurs de l'Institut Max Planck pour la recherche sur le m\u00e9tabolisme ont \u00e9valu\u00e9 comment l'apprentissage associatif change chez les personnes pr\u00e9sentant une sensibilit\u00e9 alt\u00e9r\u00e9e \u00e0 l'insuline associ\u00e9e \u00e0 l'ob\u00e9sit\u00e9. Ils ont \u00e9tudi\u00e9 les comportements d'apprentissage associ\u00e9s dans deux groupes de participants; l'un avec un poids normal, qui avait une sensibilit\u00e9 \u00e9lev\u00e9e \u00e0 l'insuline, et l'autre avec une sensibilit\u00e9 r\u00e9duite \u00e0 l'insuline due \u00e0 l'ob\u00e9sit\u00e9. L'\u00e9quipe a d\u00e9couvert que la r\u00e9duction de la sensibilit\u00e9 \u00e0 l'insuline due \u00e0 l'ob\u00e9sit\u00e9 alt\u00e8re l'apprentissage associatif.<\/p>\n

Les participants du groupe ob\u00e8se ont re\u00e7u soit un placebo, soit du liraglutide \u2013 un medicament pour maigrir<\/a> prescrit pour l'ob\u00e9sit\u00e9 et le diab\u00e8te de type 2.<\/p>\n

Avec une seule dose de liraglutide, l'apprentissage associatif alt\u00e9r\u00e9 chez les personnes ob\u00e8ses peut \u00eatre invers\u00e9 et ramen\u00e9 au m\u00eame niveau que celui des personnes de poids normal, selon les r\u00e9sultats publi\u00e9s dans la revue Nature Metabolism.<\/p>\n

\u00ab Ces d\u00e9couvertes sont d'une importance fondamentale. Nous montrons ici que les comportements de base tels que l'apprentissage associatif d\u00e9pendent non seulement des conditions environnementales externes mais aussi de l'\u00e9tat m\u00e9tabolique du corps. Ainsi, le fait qu'une personne soit en surpoids ou non d\u00e9termine \u00e9galement comment le cerveau apprend \u00e0 associer les signaux sensoriels et quelle motivation est g\u00e9n\u00e9r\u00e9e. La normalisation que nous avons obtenue avec le m\u00e9dicament chez les sujets ob\u00e8ses correspond donc aux \u00e9tudes montrant que ces m\u00e9dicaments r\u00e9tablissent une sensation normale de sati\u00e9t\u00e9, obligeant les gens \u00e0 manger moins et donc \u00e0 perdre du poids \u00bb, a d\u00e9clar\u00e9 le responsable de l'\u00e9tude, Marc Tittgemeyer. communiqu\u00e9 de presse<\/a>.<\/p>\n

L'\u00e9tude montre comment l'ob\u00e9sit\u00e9 peut alt\u00e9rer le cerveau et comment le processus peut \u00eatre modifi\u00e9 avec des m\u00e9dicaments. Les chercheurs pr\u00e9voient de mener d'autres \u00e9tudes pour comprendre le fonctionnement du liraglutide \u00e0 un niveau niveau mol\u00e9culaire<\/a>. Ils pr\u00e9voient \u00e9galement d'explorer si d'autres approches telles que les essais de perte de poids et les sensibilisateurs \u00e0 l'insuline peuvent \u00e9galement apporter des am\u00e9liorations similaires.<\/p>\n

"Bien qu'il soit encourageant que les m\u00e9dicaments disponibles aient un effet positif sur l'activit\u00e9 c\u00e9r\u00e9brale dans l'ob\u00e9sit\u00e9, il est alarmant que des changements dans les performances c\u00e9r\u00e9brales se produisent m\u00eame chez les jeunes ob\u00e8ses sans autres conditions m\u00e9dicales. La pr\u00e9vention de l'ob\u00e9sit\u00e9 devrait jouer un r\u00f4le beaucoup plus important dans notre syst\u00e8me de sant\u00e9 \u00e0 l'avenir. La m\u00e9dication \u00e0 vie est l'option la moins appr\u00e9ci\u00e9e par rapport \u00e0 la pr\u00e9vention primaire de l'ob\u00e9sit\u00e9 et des complications associ\u00e9es \u00bb, a d\u00e9clar\u00e9 Ruth Han\u00dfen, premi\u00e8re auteure de l'\u00e9tude et m\u00e9decin \u00e0 l'h\u00f4pital universitaire de Cologne.<\/p>\n

Publi\u00e9 par Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8589,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8588","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nA Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A drug prescribed for weight loss and type 2 diabetes may improve associative learning in people with obesity, a recent study has found.Associative learning is the process by which living things learn about the connections between things happening around them. It involves both modifications of existing behaviors and the development of new behaviors.Researchers from Max Planck Institute for Metabolism Research evaluated how associative learning changes in people with impaired insulin sensitivity associated with obesity. They studied associated learning behaviors in two groups of participants; one with normal weight, who had high insulin sensitivity, and the other with reduced insulin sensitivity from obesity. The team found that reduced insulin sensitivity from obesity impairs associative learning.The participants in the obese group were either given a placebo or liraglutide \u2013 a weight loss drug prescribed for obesity and type 2 diabetes.With a single dose of liraglutide, the impaired associative learning in obese people can be reversed and brought back to the levels same as that of people with normal weight, according to the findings, published in the journal Nature Metabolism."These findings are of fundamental importance. We show here that basic behaviors such as associative learning depend not only on external environmental conditions but also on the body's metabolic state. So, whether someone has overweight or not also determines how the brain learns to associate sensory signals and what motivation is generated. The normalization we achieved with the drug in subjects with obesity, therefore, fits with studies showing that these drugs restore a normal feeling of satiety, causing people to eat less and therefore lose weight," study leader Marc Tittgemeyer said in a news release.The study shows how obesity can alter the brain and how the process can be modified with medication. The researchers plan to carry out further studies to understand how liraglutide works at a molecular level. They also plan to explore if other approaches such as weight loss trials and insulin sensitizers can also bring in similar improvements."While it is encouraging that available drugs have a positive effect on brain activity in obesity, it is alarming that changes in brain performance occur even in young people with obesity without other medical conditions. Obesity prevention should play a much greater role in our healthcare system in the future. Lifelong medication is the less preferred option in comparison to primary prevention of obesity and associated complications," said Ruth Han\u00dfen, first author of the study and a physician at the University Hospital of Cologne.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-08-18T07:54:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity\",\"datePublished\":\"2023-08-18T07:54:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\"},\"wordCount\":438,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\",\"url\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\",\"name\":\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - 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Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/fr\/un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses\/","og_locale":"fr_FR","og_type":"article","og_title":"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - Urban Care Clinic","og_description":"A drug prescribed for weight loss and type 2 diabetes may improve associative learning in people with obesity, a recent study has found.Associative learning is the process by which living things learn about the connections between things happening around them. It involves both modifications of existing behaviors and the development of new behaviors.Researchers from Max Planck Institute for Metabolism Research evaluated how associative learning changes in people with impaired insulin sensitivity associated with obesity. They studied associated learning behaviors in two groups of participants; one with normal weight, who had high insulin sensitivity, and the other with reduced insulin sensitivity from obesity. The team found that reduced insulin sensitivity from obesity impairs associative learning.The participants in the obese group were either given a placebo or liraglutide \u2013 a weight loss drug prescribed for obesity and type 2 diabetes.With a single dose of liraglutide, the impaired associative learning in obese people can be reversed and brought back to the levels same as that of people with normal weight, according to the findings, published in the journal Nature Metabolism.\"These findings are of fundamental importance. We show here that basic behaviors such as associative learning depend not only on external environmental conditions but also on the body's metabolic state. So, whether someone has overweight or not also determines how the brain learns to associate sensory signals and what motivation is generated. The normalization we achieved with the drug in subjects with obesity, therefore, fits with studies showing that these drugs restore a normal feeling of satiety, causing people to eat less and therefore lose weight,\" study leader Marc Tittgemeyer said in a news release.The study shows how obesity can alter the brain and how the process can be modified with medication. The researchers plan to carry out further studies to understand how liraglutide works at a molecular level. They also plan to explore if other approaches such as weight loss trials and insulin sensitizers can also bring in similar improvements.\"While it is encouraging that available drugs have a positive effect on brain activity in obesity, it is alarming that changes in brain performance occur even in young people with obesity without other medical conditions. Obesity prevention should play a much greater role in our healthcare system in the future. Lifelong medication is the less preferred option in comparison to primary prevention of obesity and associated complications,\" said Ruth Han\u00dfen, first author of the study and a physician at the University Hospital of Cologne.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/fr\/un-medicament-prescrit-pour-perdre-du-poids-pourrait-aider-a-ameliorer-lapprentissage-associatif-chez-les-personnes-obeses\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-08-18T07:54:45+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg","type":"","width":"","height":""}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_image":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg","twitter_misc":{"\u00c9crit par":"Urban Care Clinic","Dur\u00e9e de lecture estim\u00e9e":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c"},"headline":"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With 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