{"id":8301,"date":"2023-06-05T09:24:37","date_gmt":"2023-06-05T06:24:37","guid":{"rendered":"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/"},"modified":"2023-06-05T09:24:37","modified_gmt":"2023-06-05T06:24:37","slug":"ladolescence-pourrait-etre-le-meilleur-moment-pour-traiter-lautisme-schizophrene","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/ladolescence-pourrait-etre-le-meilleur-moment-pour-traiter-lautisme-schizophrene\/","title":{"rendered":"L'adolescence pourrait \u00eatre le meilleur moment pour traiter la schizophr\u00e9nie et l'autisme"},"content":{"rendered":"

Les scientifiques ont identifi\u00e9 une fen\u00eatre potentielle pour le traitement des troubles neuropsychiatriques caus\u00e9s par un dysfonctionnement de la dopamine.<\/p>\n

La derni\u00e8re \u00e9tude men\u00e9e par des chercheurs de l'Universit\u00e9 de Rochester a r\u00e9v\u00e9l\u00e9 que l'adolescence est le meilleur moment pour traiter des affections telles que la schizophr\u00e9nie et l'autisme, toutes deux caract\u00e9ris\u00e9es par un dysfonctionnement du syst\u00e8me dopaminergique.<\/p>\n

Les personnes autistes ont bas niveaux<\/a> de dopamine. Des \u00e9tudes montrent que cela pourrait r\u00e9duire leur motivation \u00e0 poursuivre des interactions sociales car leur cerveau enregistre ces activit\u00e9s comme non gratifiantes.<\/p>\n

Chez les schizophr\u00e8nes, niveaux de dopamine<\/a> peut \u00eatre trop \u00e9lev\u00e9 ou trop bas. Une augmentation anormale de l'activit\u00e9 de la dopamine dans certaines parties du cerveau provoque des sympt\u00f4mes positifs de la schizophr\u00e9nie tels que des hallucinations ou des d\u00e9lires. Les sympt\u00f4mes positifs font r\u00e9f\u00e9rence \u00e0 des changements de comportements ou de pens\u00e9es apr\u00e8s qu'un individu a d\u00e9velopp\u00e9 une schizophr\u00e9nie.<\/p>\n

Lorsque l'activit\u00e9 de la dopamine est trop faible dans certaines parties du cerveau, les patients schizophr\u00e8nes peuvent montrer sympt\u00f4mes n\u00e9gatifs<\/a> et les sympt\u00f4mes cognitifs. Les sympt\u00f4mes n\u00e9gatifs sont marqu\u00e9s par l'absence de comportement normal, tandis que les sympt\u00f4mes cognitifs incluent des probl\u00e8mes de concentration et d'attention.<\/p>\n

Dans le dernier \u00e9tude<\/a>, les chercheurs ont stimul\u00e9 les cellules neuronales sous-performantes qui fournissent de la dopamine au cortex frontal du cerveau chez la souris. Ils ont d\u00e9couvert que l'activation aide \u00e0 renforcer le circuit essentiel au traitement cognitif sup\u00e9rieur et \u00e0 la prise de d\u00e9cision.<\/p>\n

Dans une \u00e9tude pr\u00e9c\u00e9dente, l'\u00e9quipe a identifi\u00e9 que le bras sp\u00e9cifique du syst\u00e8me dopaminergique \u00e9tait plus flexible dans le cerveau des adolescents que chez les adultes. La derni\u00e8re \u00e9tude sugg\u00e8re que cette fen\u00eatre est une opportunit\u00e9 pour une intervention th\u00e9rapeutique.<\/p>\n

\u00ab Le d\u00e9veloppement du cerveau est un processus long, et de nombreux syst\u00e8mes neuronaux ont des fen\u00eatres critiques \u2013 des moments cl\u00e9s o\u00f9 les zones c\u00e9r\u00e9brales sont mall\u00e9ables et subissent les derni\u00e8res \u00e9tapes de maturation. En identifiant ces fen\u00eatres, nous pouvons cibler les interventions sur ces p\u00e9riodes et \u00e9ventuellement modifier le cours d'une maladie en sauvant les d\u00e9ficits structurels et comportementaux caus\u00e9s par ces troubles \u00bb, a dit<\/a> Rianne Stowell, co-premi\u00e8re auteur de l'\u00e9tude.<\/p>\n

Les chercheurs pensent que cette d\u00e9couverte leur permettra de trouver une cible possible pour le traitement des troubles neuropsychiatriques.<\/p>\n

"Ces r\u00e9sultats sugg\u00e8rent que l'augmentation de l'activit\u00e9 du circuit dopaminergique de l'adolescent peut sauver les d\u00e9ficits existants dans le circuit et que cet effet peut \u00eatre durable car ces changements persistent \u00e0 l'\u00e2ge adulte. Si nous pouvons cibler les bonnes fen\u00eatres de d\u00e9veloppement et comprendre les signaux en jeu, nous pouvons d\u00e9velopper des traitements qui modifient le cours de ces troubles c\u00e9r\u00e9braux \u00bb, a ajout\u00e9 Stowell.<\/p>\n

\n
\"teenager\"<\/picture><\/div>
\nL'adolescence est le meilleur moment pour traiter des conditions telles que la schizophr\u00e9nie et l'autisme, selon une \u00e9tude.<\/span>
\nPhoto gracieuset\u00e9 de Pexels<\/span>
\n<\/figcaption><\/figure>\n

Publi\u00e9 par Medicaldaily.com<\/p>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Les scientifiques ont identifi\u00e9 une fen\u00eatre potentielle pour le traitement des troubles neuropsychiatriques caus\u00e9s par un dysfonctionnement de la dopamine.<\/p>\n

La derni\u00e8re \u00e9tude men\u00e9e par des chercheurs de l'Universit\u00e9 de Rochester a r\u00e9v\u00e9l\u00e9 que l'adolescence est le meilleur moment pour traiter des affections telles que la schizophr\u00e9nie et l'autisme, toutes deux caract\u00e9ris\u00e9es par un dysfonctionnement du syst\u00e8me dopaminergique.<\/p>\n

Les personnes autistes ont bas niveaux<\/a> de dopamine. Des \u00e9tudes montrent que cela pourrait r\u00e9duire leur motivation \u00e0 poursuivre des interactions sociales car leur cerveau enregistre ces activit\u00e9s comme non gratifiantes.<\/p>\n

Chez les schizophr\u00e8nes, niveaux de dopamine<\/a> peut \u00eatre trop \u00e9lev\u00e9 ou trop bas. Une augmentation anormale de l'activit\u00e9 de la dopamine dans certaines parties du cerveau provoque des sympt\u00f4mes positifs de la schizophr\u00e9nie tels que des hallucinations ou des d\u00e9lires. Les sympt\u00f4mes positifs font r\u00e9f\u00e9rence \u00e0 des changements de comportements ou de pens\u00e9es apr\u00e8s qu'un individu a d\u00e9velopp\u00e9 une schizophr\u00e9nie.<\/p>\n

Lorsque l'activit\u00e9 de la dopamine est trop faible dans certaines parties du cerveau, les patients schizophr\u00e8nes peuvent montrer sympt\u00f4mes n\u00e9gatifs<\/a> et les sympt\u00f4mes cognitifs. Les sympt\u00f4mes n\u00e9gatifs sont marqu\u00e9s par l'absence de comportement normal, tandis que les sympt\u00f4mes cognitifs incluent des probl\u00e8mes de concentration et d'attention.<\/p>\n

Dans le dernier \u00e9tude<\/a>, les chercheurs ont stimul\u00e9 les cellules neuronales sous-performantes qui fournissent de la dopamine au cortex frontal du cerveau chez la souris. Ils ont d\u00e9couvert que l'activation aide \u00e0 renforcer le circuit essentiel au traitement cognitif sup\u00e9rieur et \u00e0 la prise de d\u00e9cision.<\/p>\n

Dans une \u00e9tude pr\u00e9c\u00e9dente, l'\u00e9quipe a identifi\u00e9 que le bras sp\u00e9cifique du syst\u00e8me dopaminergique \u00e9tait plus flexible dans le cerveau des adolescents que chez les adultes. La derni\u00e8re \u00e9tude sugg\u00e8re que cette fen\u00eatre est une opportunit\u00e9 pour une intervention th\u00e9rapeutique.<\/p>\n

\u00ab Le d\u00e9veloppement du cerveau est un processus long, et de nombreux syst\u00e8mes neuronaux ont des fen\u00eatres critiques \u2013 des moments cl\u00e9s o\u00f9 les zones c\u00e9r\u00e9brales sont mall\u00e9ables et subissent les derni\u00e8res \u00e9tapes de maturation. En identifiant ces fen\u00eatres, nous pouvons cibler les interventions sur ces p\u00e9riodes et \u00e9ventuellement modifier le cours d'une maladie en sauvant les d\u00e9ficits structurels et comportementaux caus\u00e9s par ces troubles \u00bb, a dit<\/a> Rianne Stowell, co-premi\u00e8re auteur de l'\u00e9tude.<\/p>\n

Les chercheurs pensent que cette d\u00e9couverte leur permettra de trouver une cible possible pour le traitement des troubles neuropsychiatriques.<\/p>\n

"Ces r\u00e9sultats sugg\u00e8rent que l'augmentation de l'activit\u00e9 du circuit dopaminergique de l'adolescent peut sauver les d\u00e9ficits existants dans le circuit et que cet effet peut \u00eatre durable car ces changements persistent \u00e0 l'\u00e2ge adulte. Si nous pouvons cibler les bonnes fen\u00eatres de d\u00e9veloppement et comprendre les signaux en jeu, nous pouvons d\u00e9velopper des traitements qui modifient le cours de ces troubles c\u00e9r\u00e9braux \u00bb, a ajout\u00e9 Stowell.<\/p>\n

\n
\"teenager\"<\/div>
\nL'adolescence est le meilleur moment pour traiter des conditions telles que la schizophr\u00e9nie et l'autisme, selon une \u00e9tude.<\/span>
\nPhoto gracieuset\u00e9 de Pexels<\/span>
\n<\/figcaption><\/figure>\n

Publi\u00e9 par Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8302,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8301","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nAdolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/ladolescence-pourrait-etre-le-meilleur-moment-pour-traiter-lautisme-schizophrene\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Scientists have identified a potential window for treating neuropsychiatric disorders caused by dopamine dysfunction.The latest study by researchers from the University of Rochester has found that adolescence is the best time to treat conditions such as schizophrenia and autism, both characterized by dysfunctioning of the dopamine system.Autistic individuals have low levels of dopamine. Studies show this could reduce their motivation to pursue social interactions as their brains register these activities as not rewarding.In schizophrenic individuals, dopamine levels can either be too high or too low. Abnormal increase in dopamine activity in certain parts of the brain causes positive symptoms of schizophrenia such as hallucinations or delusions. Positive symptoms refer to changes in behaviors or thoughts after an individual develops schizophrenia.When dopamine activity is too low in certain parts of the brain, schizophrenic patients can show negative symptoms and cognitive symptoms. Negative symptoms are marked by the absence of normal behavior, while cognitive symptoms include issues with focusing and attention.In the latest study, researchers stimulated the underperforming neuron cells that provide dopamine to the frontal cortex of the brain in mice. They found that the activation helps in strengthening the circuit essential for higher cognitive processing and decision-making.In a previous study, the team identified the specific arm of the dopamine system was more flexible in the adolescent brain than in adults. The latest study suggests this window is an opportunity for therapeutic intervention."Brain development is a lengthy process, and many neuronal systems have critical windows \u2013 key times when brain areas are malleable and undergoing final maturation steps. By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders," said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders."These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders," Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. Photo Courtesy of Pexels Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/ladolescence-pourrait-etre-le-meilleur-moment-pour-traiter-lautisme-schizophrene\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-05T06:24:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism\",\"datePublished\":\"2023-06-05T06:24:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"wordCount\":420,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"url\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"name\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - 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Studies show this could reduce their motivation to pursue social interactions as their brains register these activities as not rewarding.In schizophrenic individuals, dopamine levels can either be too high or too low. Abnormal increase in dopamine activity in certain parts of the brain causes positive symptoms of schizophrenia such as hallucinations or delusions. Positive symptoms refer to changes in behaviors or thoughts after an individual develops schizophrenia.When dopamine activity is too low in certain parts of the brain, schizophrenic patients can show negative symptoms and cognitive symptoms. Negative symptoms are marked by the absence of normal behavior, while cognitive symptoms include issues with focusing and attention.In the latest study, researchers stimulated the underperforming neuron cells that provide dopamine to the frontal cortex of the brain in mice. They found that the activation helps in strengthening the circuit essential for higher cognitive processing and decision-making.In a previous study, the team identified the specific arm of the dopamine system was more flexible in the adolescent brain than in adults. The latest study suggests this window is an opportunity for therapeutic intervention.\"Brain development is a lengthy process, and many neuronal systems have critical windows \u2013 key times when brain areas are malleable and undergoing final maturation steps. By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders,\" said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders.\"These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders,\" Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. 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