{"id":8202,"date":"2023-05-19T03:24:07","date_gmt":"2023-05-19T00:24:07","guid":{"rendered":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"modified":"2023-05-23T17:29:53","modified_gmt":"2023-05-23T14:29:53","slug":"qui-veut-que-les-fabricants-de-vaccins-abandonnent-la-souche-originale-dans-les-formulations-mises-a-jour","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","title":{"rendered":"L&#039;OMS veut que les fabricants de vaccins abandonnent la souche originale dans des formulations mises \u00e0 jour"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>L\u2019Organisation mondiale de la sant\u00e9 (OMS) a publi\u00e9 une d\u00e9claration sur la composition antig\u00e9nique des vaccins contre la COVID-19.<\/p>\n<p>L&#039;agence sp\u00e9cialis\u00e9e des Nations Unies a d\u00e9clar\u00e9 jeudi que les fabricants de vaccins devraient concevoir des mises \u00e0 jour qui ne ciblent plus la souche originale du SRAS-CoV-2.<\/p>\n<p>&quot;Bien que les vaccins contre la COVID-19 actuellement approuv\u00e9s, y compris ceux bas\u00e9s sur le virus index, continuent de fournir une protection contre les maladies graves, le TAG-CO-VAC conseille de s&#039;\u00e9loigner de l&#039;inclusion du virus index dans les futures formulations de vaccins contre la COVID-19, &quot; le <a rel=\"noopener nofollow\" href=\"https:\/\/www.who.int\/news\/item\/18-05-2023-statement-on-the-antigen-composition-of-covid-19-vaccines\" target=\"_blank\">L&#039;OMS a d\u00e9clar\u00e9 sur son site Internet<\/a>.<\/p>\n<p>TAG-CO-VAC est le groupe consultatif technique de l&#039;OMS sur la composition du vaccin contre la COVID-19. Le groupe consultatif est charg\u00e9 de se r\u00e9unir r\u00e9guli\u00e8rement pour \u00e9valuer les implications des mutations plus r\u00e9centes sur la composition antig\u00e9nique des futurs vaccins.<\/p>\n<p>Cette ann\u00e9e, le TAG-CO-VAC devrait se r\u00e9unir au moins deux fois. La premi\u00e8re \u00e9tait pr\u00e9vue en mai, et un suivi devrait \u00eatre fait environ six mois plus tard. Le groupe s&#039;est officiellement r\u00e9uni les 11 et 12 mai pour discuter des derni\u00e8res donn\u00e9es sur les variantes du SRAS-CoV-2 en circulation et la composition du vaccin.<\/p>\n<p>L&#039;ann\u00e9e derni\u00e8re, <a rel=\"noopener nofollow\" href=\"https:\/\/www.who.int\/news\/item\/17-06-2022-interim-statement-on--the-composition-of-current-COVID-19-vaccines\" target=\"_blank\">TAG-CO-VAC a d\u00e9clar\u00e9<\/a> que l\u2019objectif de la mise \u00e0 jour de la composition antig\u00e9nique du vaccin COVID-19 \u00e9tait d\u2019am\u00e9liorer les r\u00e9ponses immunitaires induites par le vaccin contre les variantes du coronavirus actuellement en circulation. Si le groupe devait s&#039;apercevoir qu&#039;il \u00e9tait n\u00e9cessaire de modifier les formulations, il conseillerait \u00e0 l&#039;OMS d&#039;en informer tous les fabricants de vaccins.<\/p>\n<p>La derni\u00e8re recommandation du groupe d&#039;abandonner la souche originale dans les futures formulations est due \u00e0 plusieurs raisons. L\u2019un d\u2019eux concerne le virus index et d\u2019autres souches ant\u00e9rieures qui ne circulent plus chez l\u2019homme. Une autre raison est la fa\u00e7on dont la souche originale produit des niveaux ind\u00e9tectables ou tr\u00e8s faibles d\u2019anticorps neutralisants contre les nouvelles variantes.<\/p>\n<p>La troisi\u00e8me raison invoqu\u00e9e par le groupe a quelque chose \u00e0 voir avec la concentration de la composition. En incluant le virus index dans les vaccins bivalents ou multivalents et les rappels, la concentration des nouveaux antig\u00e8nes cibles peut \u00eatre inf\u00e9rieure. Cela diminue l\u2019ampleur de la r\u00e9ponse immunitaire humorale contre les variantes actuellement en circulation.<\/p>\n<p>TAG-CO-VAC a reconnu les limites des donn\u00e9es disponibles sur le calendrier, les mutations sp\u00e9cifiques, les caract\u00e9ristiques antig\u00e9niques et les risques potentiels pour la sant\u00e9 publique des futurs variants. Les informations sur la r\u00e9activit\u00e9 crois\u00e9e des r\u00e9ponses immunitaires provoqu\u00e9es par les nouvelles souches sont \u00e9galement limit\u00e9es. Pendant ce temps, les donn\u00e9es sur les vaccins candidats contre la lign\u00e9e descendante de XBB.1 sont encore limit\u00e9es aux mod\u00e8les animaux.<\/p>\n<p>Malgr\u00e9 les limites, le groupe consultatif a d\u00e9clar\u00e9 qu&#039;il continue d&#039;encourager le d\u00e9veloppement futur de vaccins contre la COVID-19 qui renforcent l&#039;immunit\u00e9 des muqueuses pour une meilleure protection contre les infections virales et r\u00e9duisent la transmission du SRAS-CoV-2, en particulier dans le <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/how-stay-safe-post-pandemic-era-469772\">\u00e8re post-pand\u00e9mique<\/a>.<\/p>\n<p>Publi\u00e9 par Medicaldaily.com<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/who-wants-vaccine-manufacturers-ditch-original-strain-updated-formulations-469822\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\" class=\"ff-og-image-inserted\"><\/div>\n<p>L\u2019Organisation mondiale de la sant\u00e9 (OMS) a publi\u00e9 une d\u00e9claration sur la composition antig\u00e9nique des vaccins contre la COVID-19.<\/p>\n<p>L&#039;agence sp\u00e9cialis\u00e9e des Nations Unies a d\u00e9clar\u00e9 jeudi que les fabricants de vaccins devraient concevoir des mises \u00e0 jour qui ne ciblent plus la souche originale du SRAS-CoV-2.<\/p>\n<p>&quot;Bien que les vaccins contre la COVID-19 actuellement approuv\u00e9s, y compris ceux bas\u00e9s sur le virus index, continuent de fournir une protection contre les maladies graves, le TAG-CO-VAC conseille de s&#039;\u00e9loigner de l&#039;inclusion du virus index dans les futures formulations de vaccins contre la COVID-19, &quot; le <a rel=\"noopener nofollow\" href=\"https:\/\/www.who.int\/news\/item\/18-05-2023-statement-on-the-antigen-composition-of-covid-19-vaccines\" target=\"_blank\">L&#039;OMS a d\u00e9clar\u00e9 sur son site Internet<\/a>.<\/p>\n<p>TAG-CO-VAC est le groupe consultatif technique de l&#039;OMS sur la composition du vaccin contre la COVID-19. Le groupe consultatif est charg\u00e9 de se r\u00e9unir r\u00e9guli\u00e8rement pour \u00e9valuer les implications des mutations plus r\u00e9centes sur la composition antig\u00e9nique des futurs vaccins.<\/p>\n<p>Cette ann\u00e9e, le TAG-CO-VAC devrait se r\u00e9unir au moins deux fois. La premi\u00e8re \u00e9tait pr\u00e9vue en mai, et un suivi devrait \u00eatre fait environ six mois plus tard. Le groupe s&#039;est officiellement r\u00e9uni les 11 et 12 mai pour discuter des derni\u00e8res donn\u00e9es sur les variantes du SRAS-CoV-2 en circulation et la composition du vaccin.<\/p>\n<p>L&#039;ann\u00e9e derni\u00e8re, <a rel=\"noopener nofollow\" href=\"https:\/\/www.who.int\/news\/item\/17-06-2022-interim-statement-on--the-composition-of-current-COVID-19-vaccines\" target=\"_blank\">TAG-CO-VAC a d\u00e9clar\u00e9<\/a> que l\u2019objectif de la mise \u00e0 jour de la composition antig\u00e9nique du vaccin COVID-19 \u00e9tait d\u2019am\u00e9liorer les r\u00e9ponses immunitaires induites par le vaccin contre les variantes du coronavirus actuellement en circulation. Si le groupe devait s&#039;apercevoir qu&#039;il \u00e9tait n\u00e9cessaire de modifier les formulations, il conseillerait \u00e0 l&#039;OMS d&#039;en informer tous les fabricants de vaccins.<\/p>\n<p>La derni\u00e8re recommandation du groupe d&#039;abandonner la souche originale dans les futures formulations est due \u00e0 plusieurs raisons. L\u2019un d\u2019eux concerne le virus index et d\u2019autres souches ant\u00e9rieures qui ne circulent plus chez l\u2019homme. Une autre raison est la fa\u00e7on dont la souche originale produit des niveaux ind\u00e9tectables ou tr\u00e8s faibles d\u2019anticorps neutralisants contre les nouvelles variantes.<\/p>\n<p>La troisi\u00e8me raison invoqu\u00e9e par le groupe a quelque chose \u00e0 voir avec la concentration de la composition. En incluant le virus index dans les vaccins bivalents ou multivalents et les rappels, la concentration des nouveaux antig\u00e8nes cibles peut \u00eatre inf\u00e9rieure. Cela diminue l\u2019ampleur de la r\u00e9ponse immunitaire humorale contre les variantes actuellement en circulation.<\/p>\n<p>TAG-CO-VAC a reconnu les limites des donn\u00e9es disponibles sur le calendrier, les mutations sp\u00e9cifiques, les caract\u00e9ristiques antig\u00e9niques et les risques potentiels pour la sant\u00e9 publique des futurs variants. Les informations sur la r\u00e9activit\u00e9 crois\u00e9e des r\u00e9ponses immunitaires provoqu\u00e9es par les nouvelles souches sont \u00e9galement limit\u00e9es. Pendant ce temps, les donn\u00e9es sur les vaccins candidats contre la lign\u00e9e descendante de XBB.1 sont encore limit\u00e9es aux mod\u00e8les animaux.<\/p>\n<p>Malgr\u00e9 les limites, le groupe consultatif a d\u00e9clar\u00e9 qu&#039;il continue d&#039;encourager le d\u00e9veloppement futur de vaccins contre la COVID-19 qui renforcent l&#039;immunit\u00e9 des muqueuses pour une meilleure protection contre les infections virales et r\u00e9duisent la transmission du SRAS-CoV-2, en particulier dans le <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/how-stay-safe-post-pandemic-era-469772\">\u00e8re post-pand\u00e9mique<\/a>.<\/p>\n<p>Publi\u00e9 par Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8203,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[193],"class_list":["post-8202","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-vaccination"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/qui-veut-que-les-fabricants-de-vaccins-abandonnent-la-souche-originale-dans-les-formulations-mises-a-jour\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"The World Health Organization (WHO) has issued a statement on the antigen composition of the COVID-19 vaccines.The specialized agency of the United Nations said Thursday that vaccine manufacturers should design updates that no longer target the original strain of SARS-CoV-2.&quot;While currently approved COVID-19 vaccines, including those based on the index virus, continue to provide protection against severe disease, the TAG-CO-VAC advises moving away from the inclusion of the index virus in future formulations of COVID-19 vaccines,&quot; the WHO stated on its website.TAG-CO-VAC is the WHO&#039;s Technical Advisory Group on COVID-19 Vaccine Composition. The advisory group is tasked to convene regularly to assess the implications of newer mutations for the antigen composition of future vaccines.For this year, TAG-CO-VAC is expected to meet at least twice. The first one was scheduled in May, and a follow-up should be done about six months later. The group officially convened on May 11-12 to discuss the latest data on circulating SARS-CoV-2 variants and vaccine composition.Last year, TAG-CO-VAC stated that the objective of updating the COVID-19 vaccine antigen composition was to enhance vaccine-induced immune responses to currently circulating coronavirus variants. Should the group find the need to change formulations, it would advise the WHO to inform all vaccine manufacturers.The latest recommendation of the group to ditch the original strain in future formulations is due to several reasons. One of which has to do with the index virus and other earlier strains no longer circulating in humans. Another reason is how the original strain elicits undetectable or very low levels of neutralizing antibodies against the newer variants.The third reason cited by the group has something to do with the concentration of the composition. By including the index virus in the bivalent or multivalent vaccines and boosters, the concentration of the new target antigens may be lower. This decreases the magnitude of the humoral immune response against the currently circulating variants.TAG-CO-VAC acknowledged the limitations of the available data on the timing, specific mutations, antigenic characteristics and potential public health risks of future variants. Information on the cross-reactivity of immune responses elicited by newer strains is also limited. Meanwhile, data on candidate vaccines against XBB.1 descendent lineage are still limited to animal models.Despite the limitations, the advisory group said it continues to encourage the future development of COVID-19 vaccines that enhance mucosal immunity for improved protection against viral infection and reduce the transmission of SARS-CoV-2, especially in the post-pandemic era.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/qui-veut-que-les-fabricants-de-vaccins-abandonnent-la-souche-originale-dans-les-formulations-mises-a-jour\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-19T00:24:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-23T14:29:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\",\"datePublished\":\"2023-05-19T00:24:07+00:00\",\"dateModified\":\"2023-05-23T14:29:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"},\"wordCount\":429,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"keywords\":[\"Vaccination\"],\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\",\"name\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"datePublished\":\"2023-05-19T00:24:07+00:00\",\"dateModified\":\"2023-05-23T14:29:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#primaryimage\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"contentUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg\",\"caption\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/urbancare.clinic\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#website\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/\",\"name\":\"Urban Care Clinic\",\"description\":\"Your Medical Healthcare Clinic in Zanzibar\",\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/urbancare.clinic\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\",\"name\":\"Urban Care Clinic Zanzibar\",\"alternateName\":\"Urban Care Clinic\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/Urban-Care-Clinic-Logo-Trans-512x512-1.png\",\"contentUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/Urban-Care-Clinic-Logo-Trans-512x512-1.png\",\"width\":500,\"height\":500,\"caption\":\"Urban Care Clinic Zanzibar\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/urbancarezanzibar\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\",\"name\":\"Urban Care Clinic\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g\",\"caption\":\"Urban Care Clinic\"},\"url\":\"https:\\\/\\\/urbancare.clinic\\\/fr\\\/author\\\/urban-care-clinic\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"L&#039;OMS veut que les fabricants de vaccins abandonnent la souche originale dans les formulations mises \u00e0 jour - Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/fr\/qui-veut-que-les-fabricants-de-vaccins-abandonnent-la-souche-originale-dans-les-formulations-mises-a-jour\/","og_locale":"fr_FR","og_type":"article","og_title":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations - Urban Care Clinic","og_description":"The World Health Organization (WHO) has issued a statement on the antigen composition of the COVID-19 vaccines.The specialized agency of the United Nations said Thursday that vaccine manufacturers should design updates that no longer target the original strain of SARS-CoV-2.\"While currently approved COVID-19 vaccines, including those based on the index virus, continue to provide protection against severe disease, the TAG-CO-VAC advises moving away from the inclusion of the index virus in future formulations of COVID-19 vaccines,\" the WHO stated on its website.TAG-CO-VAC is the WHO's Technical Advisory Group on COVID-19 Vaccine Composition. The advisory group is tasked to convene regularly to assess the implications of newer mutations for the antigen composition of future vaccines.For this year, TAG-CO-VAC is expected to meet at least twice. The first one was scheduled in May, and a follow-up should be done about six months later. The group officially convened on May 11-12 to discuss the latest data on circulating SARS-CoV-2 variants and vaccine composition.Last year, TAG-CO-VAC stated that the objective of updating the COVID-19 vaccine antigen composition was to enhance vaccine-induced immune responses to currently circulating coronavirus variants. Should the group find the need to change formulations, it would advise the WHO to inform all vaccine manufacturers.The latest recommendation of the group to ditch the original strain in future formulations is due to several reasons. One of which has to do with the index virus and other earlier strains no longer circulating in humans. Another reason is how the original strain elicits undetectable or very low levels of neutralizing antibodies against the newer variants.The third reason cited by the group has something to do with the concentration of the composition. By including the index virus in the bivalent or multivalent vaccines and boosters, the concentration of the new target antigens may be lower. This decreases the magnitude of the humoral immune response against the currently circulating variants.TAG-CO-VAC acknowledged the limitations of the available data on the timing, specific mutations, antigenic characteristics and potential public health risks of future variants. Information on the cross-reactivity of immune responses elicited by newer strains is also limited. Meanwhile, data on candidate vaccines against XBB.1 descendent lineage are still limited to animal models.Despite the limitations, the advisory group said it continues to encourage the future development of COVID-19 vaccines that enhance mucosal immunity for improved protection against viral infection and reduce the transmission of SARS-CoV-2, especially in the post-pandemic era.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/fr\/qui-veut-que-les-fabricants-de-vaccins-abandonnent-la-souche-originale-dans-les-formulations-mises-a-jour\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-05-19T00:24:07+00:00","article_modified_time":"2023-05-23T14:29:53+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Urban Care Clinic","Dur\u00e9e de lecture estim\u00e9e":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations","datePublished":"2023-05-19T00:24:07+00:00","dateModified":"2023-05-23T14:29:53+00:00","mainEntityOfPage":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"},"wordCount":429,"publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"image":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","keywords":["Vaccination"],"articleSection":["Medical Daily"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","url":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/","name":"L&#039;OMS veut que les fabricants de vaccins abandonnent la souche originale dans les formulations mises \u00e0 jour - Urban Care Clinic","isPartOf":{"@id":"https:\/\/urbancare.clinic\/#website"},"primaryImageOfPage":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"image":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","datePublished":"2023-05-19T00:24:07+00:00","dateModified":"2023-05-23T14:29:53+00:00","breadcrumb":{"@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#primaryimage","url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","contentUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/05\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations.jpg","caption":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations"},{"@type":"BreadcrumbList","@id":"https:\/\/urbancare.clinic\/who-wants-vaccine-manufacturers-to-ditch-original-strain-in-updated-formulations\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/urbancare.clinic\/"},{"@type":"ListItem","position":2,"name":"WHO Wants Vaccine Manufacturers To Ditch Original Strain In Updated Formulations"}]},{"@type":"WebSite","@id":"https:\/\/urbancare.clinic\/#website","url":"https:\/\/urbancare.clinic\/","name":"Clinique de soins urbains","description":"Votre clinique de soins m\u00e9dicaux \u00e0 Zanzibar","publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/urbancare.clinic\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/urbancare.clinic\/#organization","name":"Clinique de soins urbains Zanzibar","alternateName":"Urban Care Clinic","url":"https:\/\/urbancare.clinic\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/urbancare.clinic\/#\/schema\/logo\/image\/","url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/07\/Urban-Care-Clinic-Logo-Trans-512x512-1.png","contentUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2022\/07\/Urban-Care-Clinic-Logo-Trans-512x512-1.png","width":500,"height":500,"caption":"Urban Care Clinic Zanzibar"},"image":{"@id":"https:\/\/urbancare.clinic\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/urbancarezanzibar"]},{"@type":"Person","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930","name":"Clinique de soins urbains","image":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8f8b5f9c42679ce61ae24fd31561a4574502595c4b3428a4fdf92d929bf09352?s=96&d=mm&r=g","caption":"Urban Care Clinic"},"url":"https:\/\/urbancare.clinic\/fr\/author\/urban-care-clinic\/"}]}},"_links":{"self":[{"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/posts\/8202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/comments?post=8202"}],"version-history":[{"count":0,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/posts\/8202\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/media\/8203"}],"wp:attachment":[{"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/media?parent=8202"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/categories?post=8202"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/urbancare.clinic\/fr\/wp-json\/wp\/v2\/tags?post=8202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}