{"id":7708,"date":"2023-03-29T11:13:54","date_gmt":"2023-03-29T08:13:54","guid":{"rendered":"https:\/\/urbancare.clinic\/asthma-eczema-patients-more-likely-to-develop-osteoarthritis-study-reveals\/"},"modified":"2023-05-23T17:35:45","modified_gmt":"2023-05-23T14:35:45","slug":"les-patients-atteints-dasthme-et-deczema-sont-plus-susceptibles-de-developper-une-etude-sur-larthrose","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/asthma-eczema-patients-more-likely-to-develop-osteoarthritis-study-reveals\/","title":{"rendered":"L'asthme et les patients atteints d'ecz\u00e9ma sont plus susceptibles de d\u00e9velopper de l'arthrose, r\u00e9v\u00e8le une \u00e9tude"},"content":{"rendered":"

Les personnes souffrant d'asthme ou d'ecz\u00e9ma courent un risque accru de d\u00e9velopper de l'arthrose, r\u00e9v\u00e8le une nouvelle \u00e9tude.<\/p>\n

Le \u00e9tude<\/a> publi\u00e9 dans les Annals of Rheumatic Disease lundi a en outre sugg\u00e9r\u00e9 la possibilit\u00e9 d'une voie allergique dans le d\u00e9veloppement de l'arthrose qui peut \u00eatre cibl\u00e9e avec des m\u00e9dicaments existants.<\/p>\n

Qu'est-ce que l'arthrose ?<\/strong><\/p>\n

L'arthrose est la forme la plus courante de arthrite<\/a> qui se produit lorsque le cartilage protecteur qui prot\u00e8ge les extr\u00e9mit\u00e9s des os s'use avec le temps. Environ 50 millions de personnes aux \u00c9tats-Unis souffrent d'arthrose. Les sympt\u00f4mes courants de la maladie comprennent la douleur, la raideur, la sensibilit\u00e9 au gonflement et la perte de flexibilit\u00e9.<\/p>\n

Bien que les dommages au cartilage soient irr\u00e9versibles, les m\u00e9decins recommandent aux patients de rester actifs, de maintenir un poids sant\u00e9 et de prendre des traitements pour ralentir la progression de la maladie.<\/p>\n

R\u00e9sultats de la recherche<\/strong><\/p>\n

On pensait que l'arthrose se d\u00e9veloppait \u00e0 partir de l'usure du cartilage jusqu'\u00e0 ce qu'une \u00e9tude publi\u00e9e en 2019 sugg\u00e8re qu'elle pourrait \u00eatre caus\u00e9e par une inflammation allergique.<\/p>\n

Matthew Baker, MD et professeur adjoint d'immunologie et de rhumatologie, et d'autres chercheurs ont d\u00e9cid\u00e9 d'\u00e9tudier plus avant le lien en suivant r\u00e9troactivement les personnes atteintes de maladie atopique \u00e0 partir des donn\u00e9es de r\u00e9clamation d'assurance, en se concentrant sur l'asthme et l'ecz\u00e9ma.<\/p>\n

Pour l'\u00e9tude, ils ont s\u00e9lectionn\u00e9 des personnes qui n'avaient pas d'arthrose depuis deux ans et qui ont ensuite re\u00e7u un diagnostic d'asthme ou d'ecz\u00e9ma pour former un groupe t\u00e9moin. Ils ont \u00e9galement suivi des patients qui avaient \u00e9galement deux ans sans arthrose et aucun diagnostic d'asthme ou d'ecz\u00e9ma plus tard.<\/p>\n

Les patients ont ensuite \u00e9t\u00e9 appari\u00e9s avec ceux du groupe t\u00e9moin qui avaient des caract\u00e9ristiques d\u00e9mographiques, une fr\u00e9quence de visites ambulatoires et d'autres facteurs similaires pour voir qui avait d\u00e9velopp\u00e9 de l'arthrose.<\/p>\n

Selon les r\u00e9sultats de la recherche, les patients souffrant d'asthme ou d'ecz\u00e9ma courent un risque accru de d\u00e9velopper de l'arthrose sur une p\u00e9riode d'environ 10 ans. S'il leur arrive d'avoir les deux conditions, le risque de d\u00e9velopper de l'arthrose passe \u00e0 115%.<\/p>\n

"Nos r\u00e9sultats fournissent la base de futures \u00e9tudes interventionnelles qui pourraient identifier le premier traitement pour r\u00e9duire la progression de l'arthrose", a d\u00e9clar\u00e9 Baker, l'auteur principal de l'\u00e9tude.<\/p>\n

L'\u00e9tude a \u00e9galement r\u00e9v\u00e9l\u00e9 que les patients asthmatiques pr\u00e9sentaient un risque accru de d\u00e9velopper de l'arthrose 83% par rapport aux patients souffrant d'autres maladies pulmonaires obstructives chroniques. Cette d\u00e9couverte sugg\u00e8re qu'une maladie pulmonaire sans r\u00e9ponse allergique n'active pas le facteur critique de la voie allergique pour le d\u00e9veloppement de l'arthrose.<\/p>\n

Les m\u00e9dicaments existants qui inhibent les cytokines allergiques et les mastocytes pour les crises d'asthme et le syndrome d'activation des mastocytes pourraient \u00e9ventuellement \u00eatre utilis\u00e9s pour traiter<\/a> l'arthrose, a d\u00e9clar\u00e9 Baker.<\/p>\n

"Nous avons maintenant une base solide pour \u00e9tudier cela en tant qu'intervention, pour voir si le ciblage de voies telles que l'inhibition des mastocytes ou des cytokines allergiques peut r\u00e9ellement r\u00e9duire le d\u00e9veloppement et\/ou la progression de l'arthrose", a ajout\u00e9 Baker.<\/p>\n

\n
\"arthrose\"<\/picture><\/div>
\nL'\u00e9tude a r\u00e9v\u00e9l\u00e9 que les patients souffrant d'asthme ou d'ecz\u00e9ma pr\u00e9sentent un risque accru de d\u00e9velopper de l'arthrose sur une p\u00e9riode d'environ 10 ans.<\/span>
\npixabay<\/span>
\n<\/figcaption><\/figure>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

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L'\u00e9tude sugg\u00e8re une voie allergique dans le d\u00e9veloppement de l'arthrose qui peut \u00eatre cibl\u00e9e avec des m\u00e9dicaments existants qui inhibent les cytokines et les mastocytes allergiques.<\/p>","protected":false},"author":2,"featured_media":7709,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/03\/asthma-eczema-patients-more-likely-to-develop-osteoarthritis-study-reveals.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[205],"class_list":["post-7708","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-asthma"],"yoast_head":"\nAsthma, Eczema Patients More Likely To Develop Osteoarthritis, Study Reveals - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/les-patients-atteints-dasthme-et-deczema-sont-plus-susceptibles-de-developper-une-etude-sur-larthrose\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Asthma, Eczema Patients More Likely To Develop Osteoarthritis, Study Reveals - 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