{"id":7531,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/leonine-facies-and-madarosis-in-lepromatous-leprosy\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"facies-leonin-et-madarose-dans-la-lepre-lepromateuse","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/leonine-facies-and-madarosis-in-lepromatous-leprosy\/","title":{"rendered":"Faci\u00e8s l\u00e9onin et madarose dans la l\u00e8pre l\u00e9promateuse"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un homme de 69 ans s&#039;est pr\u00e9sent\u00e9 avec une histoire de 5 ans d&#039;infiltration diffuse de la peau et de perte sensorielle progressive sur ses mains bilat\u00e9rales. Son visage pr\u00e9sentait quelques l\u00e9sions papulo-nodulaires sur le front et les joues, des plis cutan\u00e9s att\u00e9nu\u00e9s, avec une perte des cils et des sourcils (figure 1). L&#039;examen des nerfs p\u00e9riph\u00e9riques a montr\u00e9 un \u00e9paississement des nerfs cubital et tibial post\u00e9rieur bilat\u00e9raux. L&#039;examen d&#039;un frottis cutan\u00e9 en fente et l&#039;histopathologie d&#039;un nodule ont montr\u00e9 des caract\u00e9ristiques compatibles avec une multibacillaire\u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e36?rss=1\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un homme de 69 ans s&#039;est pr\u00e9sent\u00e9 avec des ant\u00e9c\u00e9dents d&#039;infiltration cutan\u00e9e diffuse et de perte sensorielle progressive au niveau de ses mains bilat\u00e9rales depuis 5 ans. Son visage pr\u00e9sentait quelques l\u00e9sions papulo-nodulaires sur le front et les joues, des plis cutan\u00e9s att\u00e9nu\u00e9s, avec une perte des cils et des sourcils (<cross-ref type=\"fig\" refid=\"F1\">Figure 1<\/cross-ref>). L\u2019examen des nerfs p\u00e9riph\u00e9riques a montr\u00e9 un \u00e9paississement des nerfs ulnaires bilat\u00e9raux et tibiaux post\u00e9rieurs. L&#039;examen par frottis cutan\u00e9 et l&#039;histopathologie d&#039;un nodule ont montr\u00e9 des caract\u00e9ristiques compatibles avec une l\u00e8pre multibacillaire. Sur la base des r\u00e9sultats cliniques et de laboratoire, le diagnostic de l\u00e8pre l\u00e9promateuse a \u00e9t\u00e9 pos\u00e9 et commenc\u00e9 avec le sch\u00e9ma th\u00e9rapeutique multidrogue de l&#039;OMS contenant de la rifampicine, de la clofazimine et de la dapsone. Notre patient pr\u00e9sentait un faci\u00e8s l\u00e9onin caract\u00e9ristique et une madarose de la l\u00e8pre l\u00e9pomateuse.<\/p>\n<p>Le faci\u00e8s l\u00e9onin est un visage qui ressemble \u00e0 celui du lion.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref> Elle survient secondairement \u00e0 une infiltration (\u00e9paississement) diffuse de la peau du front, du nez, des oreilles et du menton avec un aspect cireux et une att\u00e9nuation des rides naturelles. Elle a \u00e9t\u00e9 classiquement d\u00e9crite chez les l\u00e9promateux\u2026<\/p>","protected":false},"author":2,"featured_media":7532,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7531","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Leonine facies and madarosis in lepromatous leprosy - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/facies-leonin-et-madarose-dans-la-lepre-lepromateuse\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leonine facies and madarosis in lepromatous leprosy - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 69-year-old man presented with a 5-year history of diffuse infiltration of skin and progressive sensory loss over his bilateral hands. His face had a few papular-nodular lesions over forehead and cheeks, attenuated skin folds, with loss of eyelashes and eyebrows (figure 1). Peripheral nerve examination showed thickened bilateral ulnar and posterior tibial nerves. Slit skin smear examination and histopathology of a nodule showed features consistent with multibacillary leprosy. Based on clinical and laboratorial findings, the diagnosis of lepromatous leprosy was made and started on WHO&mdash;Multi Drug Therapy regimen containing rifampicin, clofazimine and dapsone. Our patient had characteristic leonine facies and madarosis of lepomatous leprosy. Leonine facies is a face that resembles that of lion.1 It occurs secondary to diffuse infiltration (thickening) of skin of forehead, nose, ears and chin with waxy appearance and attenuation of natural lines. It has been classically described in lepromatous...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/facies-leonin-et-madarose-dans-la-lepre-lepromateuse\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Leonine facies and madarosis in lepromatous leprosy\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\"},\"wordCount\":77,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/leonine-facies-and-madarosis-in-lepromatous-leprosy\\\/\",\"name\":\"Leonine facies and madarosis in lepromatous leprosy - 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