{"id":7523,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"leontiase-uremique-osseuse","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/uremic-leontiasis-ossea\/","title":{"rendered":"L\u00e9ontose osseuse ur\u00e9mique"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un homme de 40 ans s&#039;est pr\u00e9sent\u00e9 avec une histoire de 5 ans de changements faciaux progressifs et de difficult\u00e9 \u00e0 mastiquer. Il avait des ant\u00e9c\u00e9dents de maladie r\u00e9nale chronique et est devenu d\u00e9pendant de la dialyse \u00e0 l&#039;\u00e2ge de 17 ans. \u00c0 l&#039;examen, une saillie de la m\u00e2choire sup\u00e9rieure avec une malocclusion a \u00e9t\u00e9 observ\u00e9e. Son taux d&#039;hormone parathyro\u00efdienne intacte d\u00e9passait 2\u00a0500\u00a0pg\/mL (intervalle de r\u00e9f\u00e9rence\u00a0: 15,6 \u00e0 68,3). Le scanner du visage a montr\u00e9 un \u00e9paississement de l&#039;os cr\u00e2nien, \u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e37?rss=1\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un homme de 40 ans s&#039;est pr\u00e9sent\u00e9 avec des ant\u00e9c\u00e9dents de 5 ans de changements faciaux progressifs et de difficult\u00e9s \u00e0 m\u00e2cher. Il avait des ant\u00e9c\u00e9dents de maladie r\u00e9nale chronique et est devenu d\u00e9pendant de la dialyse \u00e0 l&#039;\u00e2ge de 17 ans. \u00c0 l&#039;examen, une m\u00e2choire sup\u00e9rieure protub\u00e9rante avec malocclusion a \u00e9t\u00e9 observ\u00e9e. Son taux d&#039;hormone parathyro\u00efdienne intacte d\u00e9passait 2500 pg\/mL (plage de r\u00e9f\u00e9rence : 15,6\u201368,3). La TDM du visage a montr\u00e9 un \u00e9paississement de l&#039;os cr\u00e2nien et une croissance excessive du maxillaire et de la mandibule (<cross-ref type=\"fig\" refid=\"F1\">figure 1A, B<\/cross-ref>). Une apparence de sel et de poivre a \u00e9t\u00e9 observ\u00e9e dans la calvaria (<cross-ref type=\"fig\" refid=\"F1\">figure 1B<\/cross-ref>, fl\u00e8che). Ces r\u00e9sultats \u00e9taient coh\u00e9rents avec une l\u00e9ontose osseuse ur\u00e9mique, une forme rare et grave d&#039;ost\u00e9odystrophie r\u00e9nale due \u00e0 une hyperparathyro\u00efdie.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref><\/p>\n<p>La l\u00e9ontose osseuse, \u00e9galement connue sous le nom de face de lion, entra\u00eene non seulement une d\u00e9figuration du patient, mais l&#039;expansion osseuse peut \u00e9galement comprimer les structures faciales voisines, telles que la cavit\u00e9 nasale et buccale, entra\u00eenant une obstruction des voies respiratoires, une dysarthrie et une dysphagie (<cross-ref type=\"fig\" refid=\"F1\">figure 1C<\/cross-ref>,&#8230;<\/p>","protected":false},"author":2,"featured_media":7524,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Uremic leontiasis ossea - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/leontiase-uremique-osseuse\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Uremic leontiasis ossea - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 40-year-old man presented with a 5-year history of progressive facial changes and difficulty chewing. He had a history of chronic kidney disease and became dialysis dependent at the age of 17. On examination, protruding upper jaw with malocclusion was observed. His intact parathyroid hormone level exceeded 2500 pg\/mL (reference range: 15.6&ndash;68.3). CT of the face showed cranial bone thickening, and overgrowth of the maxilla and mandible (figure 1A,B). Salt and pepper appearance was seen in the calvaria (figure 1B, arrow). These findings were consistent with uremic leontiasis ossea, a rare and severe form of renal osteodystrophy due to hyperparathyroidism.1 Leontiasis ossea&mdash;also known as lion face&mdash;results in not only disfigurement of the patient, but also the bony expansion may also compress the nearby facial structures, such as the nasal and oral cavity, leading to airway obstruction, dysarthria and dysphagia (figure 1C,...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/leontiase-uremique-osseuse\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Uremic leontiasis ossea\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"wordCount\":64,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/uremic-leontiasis-ossea.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"name\":\"Uremic leontiasis ossea - 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He had a history of chronic kidney disease and became dialysis dependent at the age of 17. On examination, protruding upper jaw with malocclusion was observed. His intact parathyroid hormone level exceeded 2500 pg\/mL (reference range: 15.6&ndash;68.3). CT of the face showed cranial bone thickening, and overgrowth of the maxilla and mandible (figure 1A,B). Salt and pepper appearance was seen in the calvaria (figure 1B, arrow). These findings were consistent with uremic leontiasis ossea, a rare and severe form of renal osteodystrophy due to hyperparathyroidism.1 Leontiasis ossea&mdash;also known as lion face&mdash;results in not only disfigurement of the patient, but also the bony expansion may also compress the nearby facial structures, such as the nasal and oral cavity, leading to airway obstruction, dysarthria and dysphagia (figure 1C,...","og_url":"https:\/\/urbancare.clinic\/fr\/leontiase-uremique-osseuse\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2022-11-22T10:00:22+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Urban Care Clinic"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"Uremic leontiasis ossea","datePublished":"2022-11-22T10:00:22+00:00","mainEntityOfPage":{"@id":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/"},"wordCount":64,"publisher":{"@id":"https:\/\/urbancare.clinic\/#organization"},"image":{"@id":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/#primaryimage"},"thumbnailUrl":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg","articleSection":["Research Articles"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/","url":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/","name":"L\u00e9ontiase ur\u00e9mique osseuse - 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