{"id":7515,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/multifocal-nodular-steatosis-mimicking-malignancy\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"steatose-nodulaire-multifocale-imitant-une-tumeur-maligne","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/multifocal-nodular-steatosis-mimicking-malignancy\/","title":{"rendered":"St\u00e9atose nodulaire multifocale mimant une malignit\u00e9"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Un homme auparavant en forme s&#039;est pr\u00e9sent\u00e9 avec un essoufflement. La radiographie thoracique montrait une densit\u00e9 du lobe inf\u00e9rieur droit. Les tests de la fonction h\u00e9patique, les \u00e9tudes de coagulation et les taux d&#039;alphaf\u0153toprot\u00e9ine \u00e9taient sans particularit\u00e9. L&#039;essoufflement du patient s&#039;est auto-r\u00e9solu, mais la tomodensitom\u00e9trie thoraco-abdomino-pelvienne r\u00e9alis\u00e9e pour exclure une tumeur maligne a r\u00e9v\u00e9l\u00e9 de multiples l\u00e9sions h\u00e9patiques hypodenses concernant des m\u00e9tastases (figure 1). Une biopsie h\u00e9patique percutan\u00e9e \u00e9choguid\u00e9e ciblant ces l\u00e9sions a \u00e9t\u00e9 r\u00e9alis\u00e9e avec succ\u00e8s. L&#039;histologie a montr\u00e9 un changement graisseux mais aucun signe de malignit\u00e9. Pour \u00e9viter la possibilit\u00e9 d&#039;\u00e9chantillonnage\u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e33?rss=1\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Un homme auparavant en forme pr\u00e9sentait un essoufflement. La radiographie thoracique montrait une densit\u00e9 du lobe inf\u00e9rieur droit. Les tests de la fonction h\u00e9patique, les \u00e9tudes de coagulation et les taux d&#039;alphaf\u0153toprot\u00e9ine \u00e9taient sans particularit\u00e9. L&#039;essoufflement du patient s&#039;est r\u00e9solu d&#039;eux-m\u00eames, mais un scanner thoracique-abdomen-pelvis r\u00e9alis\u00e9 pour exclure une tumeur maligne a r\u00e9v\u00e9l\u00e9 de multiples l\u00e9sions h\u00e9patiques hypodenses concernant des m\u00e9tastases (<cross-ref type=\"fig\" refid=\"F1\">Figure 1<\/cross-ref>). Une biopsie h\u00e9patique percutan\u00e9e \u00e9choguid\u00e9e ciblant ces l\u00e9sions a \u00e9t\u00e9 r\u00e9alis\u00e9e avec succ\u00e8s. L&#039;histologie a montr\u00e9 une modification graisseuse mais aucun signe de malignit\u00e9. Pour \u00e9viter tout risque d\u2019erreur d\u2019\u00e9chantillonnage, une deuxi\u00e8me biopsie des l\u00e9sions guid\u00e9e par \u00e9chographie a \u00e9t\u00e9 r\u00e9alis\u00e9e. L\u00e0 encore, aucun tissu malin n\u2019a \u00e9t\u00e9 identifi\u00e9. Une IRM du foie a \u00e9t\u00e9 r\u00e9alis\u00e9e (<cross-ref type=\"fig\" refid=\"F2\">figures 2A,B<\/cross-ref>). Les images d\u00e9phas\u00e9es montraient une perte de signal au milieu des l\u00e9sions (<cross-ref type=\"fig\" refid=\"F2\">figure 2B<\/cross-ref>), r\u00e9v\u00e9lateur de la teneur en lipides intracellulaires et \u00e9vocateur d&#039;un changement st\u00e9atosique. Le patient a \u00e9t\u00e9 diagnostiqu\u00e9 avec une st\u00e9atose nodulaire multifocale (MNS), rassur\u00e9 et lib\u00e9r\u00e9.<\/p>\n<p>Les l\u00e9sions MNS peuvent \u00eatre difficiles \u00e0 distinguer des maladies m\u00e9tastatiques car elles\u2026<\/p>","protected":false},"author":2,"featured_media":7516,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7515","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multifocal nodular steatosis mimicking malignancy - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/steatose-nodulaire-multifocale-imitant-une-tumeur-maligne\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multifocal nodular steatosis mimicking malignancy - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A previously fit man presented with breathlessness. Chest radiography showed right lower lobe density. Liver function tests, coagulation studies and alphafetoprotein levels were unremarkable. The patient&#039;s breathlessness self-resolved, but chest&ndash;abdomen&ndash;pelvis CT performed to exclude malignancy revealed multiple hypodense liver lesions concerning for metastases (figure 1). Ultrasound-guided percutaneous liver biopsy targeting these lesions was successfully carried out. Histology showed fatty change but no evidence of malignancy. To avoid the possibility of sampling error, a second ultrasound-guided biopsy of the lesions was performed. Again, no malignant tissue was identified. MRI of the liver was performed (figure 2A,B). The out-of-phase images showed signal drop-out in the middle of the lesions (figure 2B), indicative of intracellular lipid content and suggestive of steatotic change. The patient was diagnosed with multifocal nodular steatosis (MNS), reassured and discharged. MNS lesions can be difficult to distinguish from metastatic disease because they...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/steatose-nodulaire-multifocale-imitant-une-tumeur-maligne\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Multifocal nodular steatosis mimicking malignancy\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\"},\"wordCount\":81,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/multifocal-nodular-steatosis-mimicking-malignancy.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/multifocal-nodular-steatosis-mimicking-malignancy\\\/\",\"name\":\"Multifocal nodular steatosis mimicking malignancy - 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