{"id":7451,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"lesions-symetriques-de-la-substance-blanche-chez-un-patient-atteint-de-lupus-erythemateux-dissemine","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\/","title":{"rendered":"L\u00e9sions sym\u00e9triques de la substance blanche chez un patient atteint de lupus \u00e9ryth\u00e9mateux diss\u00e9min\u00e9"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-2\">Une jeune fille de 16 ans s&#039;est pr\u00e9sent\u00e9e avec deux \u00e9pisodes de c\u00e9phal\u00e9es, douleurs cervicales et vomissements au cours des 4 derniers mois. Lors du premier \u00e9pisode, elle a \u00e9t\u00e9 trait\u00e9e avec des antibiotiques pendant 5 jours, apr\u00e8s quoi des st\u00e9ro\u00efdes ont \u00e9t\u00e9 ajout\u00e9s, car ses sympt\u00f4mes n&#039;ont pas disparu. Elle a eu une aggravation des sympt\u00f4mes lorsque les st\u00e9ro\u00efdes ont \u00e9t\u00e9 r\u00e9duits avec une paralysie suppl\u00e9mentaire du droit lat\u00e9ral droit et un gonflement de l&#039;articulation du genou gauche. Elle avait une dyspn\u00e9e d&#039;effort intermittente, des \u00e9ruptions photosensibles sur les joues, une perte de poids, une p\u00e2leur et un hippocratisme digital. Elle avait une puissance de 4\/5 aux articulations bilat\u00e9rales de la hanche. \u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e25?rss=1\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Une jeune fille de 16 ans a pr\u00e9sent\u00e9 deux \u00e9pisodes de maux de t\u00eate, de douleurs cervicales et de vomissements au cours des 4 derniers mois. Lors du premier \u00e9pisode, elle a \u00e9t\u00e9 trait\u00e9e avec des antibiotiques pendant 5 jours, apr\u00e8s quoi des st\u00e9ro\u00efdes ont \u00e9t\u00e9 ajout\u00e9s, car ses sympt\u00f4mes ne se sont pas r\u00e9solus. Elle a pr\u00e9sent\u00e9 une aggravation des sympt\u00f4mes lorsque les st\u00e9ro\u00efdes ont \u00e9t\u00e9 diminu\u00e9s avec une paralysie suppl\u00e9mentaire du droit lat\u00e9ral droit et un gonflement de l&#039;articulation du genou gauche. Elle pr\u00e9sentait une dyspn\u00e9e d&#039;effort intermittente, des \u00e9ruptions cutan\u00e9es photosensibles sur les joues, une perte de poids, une p\u00e2leur et un clubbing. Elle avait une puissance de 4\/5 au niveau des articulations bilat\u00e9rales de la hanche.<\/p>\n<p>L&#039;IRM c\u00e9r\u00e9brale a montr\u00e9 des hyperintensit\u00e9s T2 confluentes bilat\u00e9ralement sym\u00e9triques dans la substance blanche p\u00e9riventriculaire, sous-corticale et profonde, ce qui serait \u00e9vocateur d&#039;une leucodystrophie (<cross-ref type=\"fig\" refid=\"F1\">figure 1A<\/cross-ref>). L&#039;examen du liquide c\u00e9phalo-rachidien (LCR) a montr\u00e9 une pression \u00e9lev\u00e9e de 37 mm Hg avec des cellules nulles et un glucose et des prot\u00e9ines normaux. La cytologie maligne du LCR \u00e9tait n\u00e9gative. L&#039;ADN du virus John Cunningham, du cytom\u00e9galovirus et du virus BK dans le LCR n&#039;\u00e9tait pas d\u00e9tectable. L&#039;ELISA VIH \u00e9tait n\u00e9gatif.<\/p>\n<p>Blanc sym\u00e9trique\u2026<\/p>","protected":false},"author":2,"featured_media":7452,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Symmetrical white matter lesions in a patient with systemic lupus erythematosus - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/lesions-symetriques-de-la-substance-blanche-chez-un-patient-atteint-de-lupus-erythemateux-dissemine\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 16-year-old girl presented with two episodes of headache, neck pain and vomiting in the last 4 months. In the first episode, she was treated with antibiotics for 5 days following which steroids were added, as her symptoms did not resolve. She had aggravation of symptoms when steroids were tapered with additional right lateral rectus palsy and left knee joint swelling. She had intermittent exertional dyspnoea, photosensitive rashes on cheeks, weight loss, pallor and clubbing. She had 4\/5 power at bilateral hip joints. MRI brain showed confluent bilaterally symmetrical T2 hyperintensities in periventricular, subcortical and deep white matter which was reported to be suggestive of leukodystrophy (figure 1A). Cerebrospinal fluid (CSF) examination showed high pressure of 37 mm Hg with nil cells and normal glucose and protein. CSF malignant cytology was negative. John Cunningham, Cytomegalovirus and BK virus DNA in CSF was not detectable. HIV ELISA was negative. Symmetrical white...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/fr\/lesions-symetriques-de-la-substance-blanche-chez-un-patient-atteint-de-lupus-erythemateux-dissemine\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\"},\"wordCount\":94,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/symmetrical-white-matter-lesions-in-a-patient-with-systemic-lupus-erythematosus\\\/\",\"name\":\"Symmetrical white matter lesions in a patient with systemic lupus erythematosus - 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