{"id":7302,"date":"2023-01-16T12:39:44","date_gmt":"2023-01-16T09:39:44","guid":{"rendered":"https:\/\/urbancare.clinic\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study\/"},"modified":"2023-01-16T12:39:44","modified_gmt":"2023-01-16T09:39:44","slug":"les-produits-chimiques-presents-dans-le-vagin-des-mamans-peuvent-etre-associes-a-une-etude-sur-les-naissances-prematurees","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study\/","title":{"rendered":"Les produits chimiques pr\u00e9sents dans le vagin d'une m\u00e8re pourraient \u00eatre associ\u00e9s \u00e0 une naissance pr\u00e9matur\u00e9e\u00a0: \u00e9tude"},"content":{"rendered":"
<\/div>\n

Une exposition environnementale peut-elle affecter les femmes enceintes ? Les produits chimiques pr\u00e9sents dans le vagin de la m\u00e8re peuvent \u00eatre associ\u00e9s \u00e0 un accouchement pr\u00e9matur\u00e9 spontan\u00e9, ont d\u00e9couvert des chercheurs.<\/p>\n

Pour leur \u00e9tude, publi\u00e9<\/a> dans Nature Microbiology, une \u00e9quipe de chercheurs a examin\u00e9 le m\u00e9tabolome vaginal de 232 femmes enceintes au deuxi\u00e8me trimestre. Le m\u00e9tabolome est essentiellement le \u00abensemble complet<\/a>\u00bb des petites mol\u00e9cules d\u2019une cellule ou d\u2019un organisme.<\/p>\n

"Le m\u00e9tabolome peut \u00eatre consid\u00e9r\u00e9 comme une lecture fonctionnelle de l'\u00e9cosyst\u00e8me dans son ensemble", a d\u00e9clar\u00e9 le co-responsable de l'\u00e9tude, Tal Korem du centre m\u00e9dical Irving de l'Universit\u00e9 Columbia (CIUMC). expliqu\u00e9<\/a> dans la version universitaire. \u00ab Le profilage du microbiome peut nous dire qui sont les microbes ; la m\u00e9tabolomique nous rapproche de la compr\u00e9hension de ce que font les microbes.<\/p>\n

Les microbes et m\u00e9tabolites vaginaux ont \u00e9t\u00e9 associ\u00e9s \u00e0 complications de grossesse<\/a>, y compris naissance pr\u00e9matur\u00e9e<\/a> \u2014 la situation dans laquelle un b\u00e9b\u00e9 na\u00eet avant 37 semaines de grossesse.<\/p>\n

<\/div>\n

La naissance pr\u00e9matur\u00e9e serait la \u00ab principale cause \u00bb de d\u00e9c\u00e8s n\u00e9onatal, ont not\u00e9 les chercheurs. Et ceux qui survivent peuvent aussi finir probl\u00e8mes en d\u00e9veloppement<\/a> tels que des probl\u00e8mes respiratoires, un retard de d\u00e9veloppement, des probl\u00e8mes d'audition ou une paralysie c\u00e9r\u00e9brale.<\/p>\n

En revanche, l'accouchement pr\u00e9matur\u00e9 spontan\u00e9 (sPTB) est un accouchement pr\u00e9matur\u00e9 qui n'est pas m\u00e9dicalement provoqu\u00e9 et repr\u00e9sente environ les deux tiers de toutes les PTB. On dit qu\u2019elle est \u00ab l\u2019une des principales causes de morbidit\u00e9 et de mortalit\u00e9 maternelles et n\u00e9onatales \u00bb.<\/p>\n

"Des enqu\u00eates ant\u00e9rieures ont sugg\u00e9r\u00e9 que les microbes et m\u00e9tabolites vaginaux pourraient \u00eatre impliqu\u00e9s dans le sPTB", ont \u00e9crit les chercheurs.<\/p>\n

Cependant, un \u00ab consensus clair \u00bb sur la relation exacte entre les deux facteurs reste largement hors de port\u00e9e.<\/p>\n

Sur les 232 femmes participant \u00e0 l\u2019\u00e9tude, 80 ont fini par accoucher pr\u00e9matur\u00e9ment.<\/p>\n

Les chercheurs ont d\u00e9couvert \u00ab des associations multiples \u00bb entre les m\u00e9tabolites vaginaux des mamans et une \u00e9ventuelle naissance pr\u00e9matur\u00e9e. Selon le CUIMC, plusieurs m\u00e9tabolites \u00e9taient en fait plus \u00e9lev\u00e9s chez eux que chez ceux qui ont accouch\u00e9 \u00e0 terme. Notamment, plusieurs m\u00e9tabolites \u00ab fortement associ\u00e9s au sPTB \u00bb \u00e9taient exog\u00e8nes ou provenaient de sources externes.<\/p>\n

"Ceux-ci comprennent la di\u00e9thanolamine (DEA), l'\u00e9thyl-b\u00eata glucoside, le tartrate et l'acide \u00e9thyl\u00e8nediaminet\u00e9traac\u00e9tique", a d\u00e9clar\u00e9 Korem, selon le CUIMC. "Bien que nous n'ayons pas identifi\u00e9 la source de ces x\u00e9nobiotiques chez nos participants, tous pouvaient \u00eatre trouv\u00e9s dans les cosm\u00e9tiques et les produits d'hygi\u00e8ne."<\/p>\n

Par exemple, la DEA n\u2019a \u00ab aucune source naturelle connue \u00bb et les femmes en \u00e2ge de procr\u00e9er y seraient \u00ab fortement expos\u00e9es \u00bb. L'\u00e9thylglucoside, en revanche, se trouve dans les produits contenant de l'alcool. Tous deux seraient des \u00ab pr\u00e9curseurs ou ingr\u00e9dients de produits hygi\u00e9niques et cosm\u00e9tiques \u00bb.<\/p>\n

"(L)e fait que tous ces produits soient document\u00e9s dans des produits hygi\u00e9niques et cosm\u00e9tiques fait craindre que certains de ces produits puissent augmenter le risque de sPTB", ont \u00e9crit les chercheurs. "Nos r\u00e9sultats co\u00efncident avec des \u00e9tudes r\u00e9centes soulevant des inqui\u00e9tudes concernant les expositions environnementales pendant la grossesse et identifient ces produits chimiques dans l'appareil reproducteur."<\/p>\n

Les chercheurs ont \u00e9galement d\u00e9velopp\u00e9 un algorithme capable de pr\u00e9dire une naissance pr\u00e9matur\u00e9e \u00ab avec une bonne pr\u00e9cision \u00bb. Cependant, il doit encore \u00eatre am\u00e9lior\u00e9 et valid\u00e9 avant de pouvoir \u00eatre utilis\u00e9 en milieu clinique, selon le CUIMC.<\/p>\n

Dans l\u2019ensemble, les chercheurs ont montr\u00e9 le potentiel de ces tests de m\u00e9tabolites pour pr\u00e9dire la sPTB et ont \u00e9galement mis en \u00e9vidence certaines expositions externes potentielles qui pourraient constituer des facteurs de risque. Il serait utile d'examiner plus en d\u00e9tail la source possible de ces expositions et de d\u00e9terminer si elles provoquent r\u00e9ellement des naissances pr\u00e9matur\u00e9es, a d\u00e9clar\u00e9 Korem.<\/p>\n

"La bonne nouvelle est que si ces produits chimiques sont en cause, il est peut-\u00eatre possible de limiter ces expositions potentiellement nocives", a-t-il ajout\u00e9.<\/p>\n

Source quotidienne m\u00e9dicale<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Les microbes et m\u00e9tabolites vaginaux ont \u00e9t\u00e9 associ\u00e9s \u00e0 des complications de la grossesse, notamment \u00e0 une naissance pr\u00e9matur\u00e9e \u2013 situation dans laquelle un b\u00e9b\u00e9 na\u00eet avant 37 semaines de grossesse.<\/p>","protected":false},"author":2,"featured_media":7303,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/chemicals-in-moms-vagina-may-be-associated-with-preterm-birth-study.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-7302","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nChemicals In Mom's Vagina May Be Associated With Preterm Birth: Study - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/fr\/les-produits-chimiques-presents-dans-le-vagin-des-mamans-peuvent-etre-associes-a-une-etude-sur-les-naissances-prematurees\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemicals In Mom's Vagina May Be Associated With Preterm Birth: Study - 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