{"id":7204,"date":"2023-01-05T06:00:00","date_gmt":"2023-01-05T03:00:00","guid":{"rendered":"https:\/\/www.medicaldaily.com\/scientists-develop-vaccine-brain-cancer-467694"},"modified":"2023-05-23T17:38:31","modified_gmt":"2023-05-23T14:38:31","slug":"des-scientifiques-developpent-un-vaccin-contre-le-cancer-du-cerveau","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/fr\/scientists-develop-vaccine-for-brain-cancer\/","title":{"rendered":"Des scientifiques d\u00e9veloppent un vaccin contre le cancer du cerveau"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/scientists-develop-vaccine-for-brain-cancer.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>Les scientifiques travaillent sur un nouveau vaccin qui pourrait pr\u00e9venir et tuer simultan\u00e9ment le cancer du cerveau.&nbsp;<\/p>\n<p>L\u2019\u00e9quipe exploite un nouveau moyen pour transformer les cellules canc\u00e9reuses en agents anticanc\u00e9reux qui pourraient \u00e9liminer les tumeurs et entra\u00eener le syst\u00e8me immunitaire \u00e0 pr\u00e9venir la r\u00e9cidive du cancer.&nbsp;<\/p>\n<p>L&#039;effort est r\u00e9alis\u00e9 dans le laboratoire de Khalid Shah, MS, Ph.D. au Brigham and Women&#039;s Hospital, les chercheurs souhaitent d\u00e9velopper un vaccin contre le cancer qui conf\u00e8re une immunit\u00e9 \u00e0 long terme contre cette maladie.&nbsp;<\/p>\n<p>Dans leur \u00e9tude publi\u00e9e dans le <a href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abo4778\" rel=\"nofollow noopener\" target=\"_blank\">M\u00e9decine translationnelle scientifique<\/a> journal Mercredi, les chercheurs ont expliqu\u00e9 pourquoi ils utilisent des cellules tumorales vivantes au lieu de cellules tumorales inactiv\u00e9es. Selon eux, cette derni\u00e8re aurait une capacit\u00e9 limit\u00e9e \u00e0 tuer les cellules tumorales avant d\u2019induire une r\u00e9ponse immunitaire. D\u2019un autre c\u00f4t\u00e9, les cellules tumorales vivantes peuvent suivre et cibler les tumeurs.&nbsp;<\/p>\n<div id=\"dfp-ad-oop2\" class=\"dfp-tag-wrapper\"> <\/div>\n<p>Pour l\u2019\u00e9tude, ils ont con\u00e7u des cellules tumorales th\u00e9rapeutiques et les ont utilis\u00e9es pour \u00e9liminer les tumeurs du glioblastome chez la souris. Le glioblastome est un type de tumeur \u00e0 croissance rapide dans le syst\u00e8me nerveux central, form\u00e9 \u00e0 partir du tissu de soutien du cerveau et de la moelle \u00e9pini\u00e8re, selon le <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/glioblastoma\" rel=\"nofollow noopener\" target=\"_blank\">Institut national du cancer<\/a>.&nbsp;<\/p>\n<p>Les cellules tumorales th\u00e9rapeutiques ont non seulement \u00e9limin\u00e9 les tumeurs, mais se sont \u00e9galement traduites par un b\u00e9n\u00e9fice en mati\u00e8re de survie et une immunit\u00e9 \u00e0 long terme dans les exp\u00e9riences sur des souris humanis\u00e9es. L\u2019\u00e9quipe a qualifi\u00e9 ce qu\u2019ils ont d\u00e9velopp\u00e9 d\u2019\u00ab immunoth\u00e9rapie cellulaire prometteuse pour les tumeurs solides \u00bb.<\/p>\n<p>&quot;Notre \u00e9quipe a poursuivi une id\u00e9e simple : prendre des cellules canc\u00e9reuses et les transformer en anticanc\u00e9reux et en vaccins&quot;, a d\u00e9clar\u00e9 Shah, l&#039;auteur correspondant de l&#039;\u00e9tude, dans un communiqu\u00e9. <a href=\"https:\/\/www.eurekalert.org\/news-releases\/975452\" rel=\"nofollow noopener\" target=\"_blank\">communiqu\u00e9 de presse<\/a>.&nbsp;<\/p>\n<p>Le vice-pr\u00e9sident de la recherche au d\u00e9partement de neurochirurgie du Brigham a poursuivi : \u00ab Gr\u00e2ce au g\u00e9nie g\u00e9n\u00e9tique, nous r\u00e9utilisant les cellules canc\u00e9reuses pour d\u00e9velopper un traitement qui tue les cellules tumorales et stimule le syst\u00e8me immunitaire pour d\u00e9truire les tumeurs primaires et pr\u00e9venir le cancer. \u00bb<\/p>\n<p>Shah a not\u00e9 que leur objectif \u00e9tait de d\u00e9velopper un \u00ab vaccin anticanc\u00e9reux \u00bb qui aurait un impact important sur la communaut\u00e9 m\u00e9dicale. Cependant, des recherches suppl\u00e9mentaires sont encore n\u00e9cessaires pour comprendre pleinement ses applications.&nbsp;<\/p>\n<p>\u00ab Dans tout le travail que nous effectuons au Centre, m\u00eame lorsqu&#039;il est tr\u00e8s technique, nous ne perdons jamais de vue le patient. Notre objectif est d\u2019adopter une approche innovante mais traduisible afin de pouvoir d\u00e9velopper un vaccin th\u00e9rapeutique anticanc\u00e9reux qui, \u00e0 terme, aura un impact durable sur la m\u00e9decine \u00bb, a-t-il d\u00e9clar\u00e9.&nbsp;<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/scientists-develop-vaccine-brain-cancer-467694?utm_source=Public&#038;utm_medium=Feed&#038;utm_campaign=Distribution\">Source quotidienne m\u00e9dicale<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Le vaccin pourrait \u00e9liminer les tumeurs et pr\u00e9venir la r\u00e9currence du cancer.<\/p>","protected":false},"author":2,"featured_media":7205,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/scientists-develop-vaccine-for-brain-cancer.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[150],"class_list":["post-7204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - 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