{"id":9151,"date":"2023-12-07T11:54:53","date_gmt":"2023-12-07T08:54:53","guid":{"rendered":"https:\/\/urbancare.simplyit.solutions\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"modified":"2023-12-07T11:54:53","modified_gmt":"2023-12-07T08:54:53","slug":"menschen-uber-50-haben-moglicherweise-eine-beschleunigte-alterung-in-mindestens-einem-organ-ein-bluttest-konnte-dies-nachweisen","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/","title":{"rendered":"Menschen \u00fcber 50 haben m\u00f6glicherweise eine beschleunigte Alterung in mindestens einem Organ; Ein Bluttest k\u00f6nnte es erkennen"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p>Jedes Organ in unserem K\u00f6rper altert unterschiedlich schnell. Forscher sagen nun, dass etwa 18% gesunder Erwachsener \u00fcber 50 Jahren in mindestens einem ihrer Organe einer beschleunigten Alterung ausgesetzt sind.<\/p>\n<p>A <a rel=\"noopener nofollow\" href=\"https:\/\/www.nature.com\/articles\/s41586-023-06802-1\" target=\"_blank\">lernen<\/a>Die von Forschern der Stanford Medicine geleitete Studie legt nahe, dass es mit einem einfachen Bluttest m\u00f6glich sein k\u00f6nnte, eine beschleunigte Alterung eines Organs festzustellen, die das Krankheitsrisiko und die Mortalit\u00e4t erh\u00f6ht.<\/p>\n<p>\u201eWir k\u00f6nnen das biologische Alter eines Organs bei einem scheinbar gesunden Menschen absch\u00e4tzen. Das wiederum sagt das Risiko einer Person f\u00fcr Krankheiten im Zusammenhang mit diesem Organ voraus.\u201c <a rel=\"noopener nofollow\" href=\"https:\/\/www.eurekalert.org\/news-releases\/1009771\" target=\"_blank\">genannt<\/a> der leitende Autor der Studie, Tony Wyss-Coray.<\/p>\n<p>\u201eZahlreiche Studien haben einzelne Zahlen ermittelt, die das biologische Alter von Individuen darstellen \u2013 das Alter, das durch eine Reihe hochentwickelter Biomarker impliziert wird \u2013 im Gegensatz zu ihrem chronischen Alter, der tats\u00e4chlichen Anzahl der Jahre, die seit ihrer Geburt vergangen sind\u201c, sagte Wyss-Coray.<\/p>\n<p>Das Team ging jedoch noch einen Schritt weiter und ermittelte das biologische Alter jedes der 11 Schl\u00fcsselorgane und Organsysteme \u2013 Herz, Fett, Lunge, Immunsystem, Niere, Leber, Muskel, Bauchspeicheldr\u00fcse, Gehirn, Gef\u00e4\u00dfsystem und Darm.<\/p>\n<p>\u201eAls wir das biologische Alter jedes dieser Organe f\u00fcr jedes Individuum mit seinen Gegenst\u00fccken in einer gro\u00dfen Gruppe von Menschen ohne offensichtliche schwere Krankheiten verglichen, stellten wir fest, dass bei 18,41 TP3T der \u00fcber 50-J\u00e4hrigen mindestens ein Organ deutlich schneller alterte als das durchschnittlich\u201c, sagte Wyss-Coray.<\/p>\n<p>F\u00fcr die Studie wurden 5.678 Teilnehmer ausgewertet. Die Ergebnisse zeigten, dass nur bei einem von 60 Teilnehmern zwei Organe schneller alterten. Die beschleunigte Alterung zweier Organe erh\u00f6ht das Sterberisiko um das 6,5-fache.<\/p>\n<p>\u201eMithilfe kommerziell erh\u00e4ltlicher Technologien und eines von ihnen selbst entwickelten Algorithmus haben die Forscher die Konzentrationen Tausender Proteine im Blut von Menschen ermittelt, festgestellt, dass fast 1.000 dieser Proteine aus dem einen oder anderen einzelnen Organ stammen, und die abweichenden Konzentrationen dieser Proteine mit entsprechenden korrespondierenden Proteinen in Verbindung gebracht.\u201c \u201eDie beschleunigte Alterung der Organe und die Anf\u00e4lligkeit f\u00fcr Krankheiten und Mortalit\u00e4t\u201c, erkl\u00e4rten die Forscher.<\/p>\n<p>Das Forschungsteam sch\u00e4tzte einen \u201eAltersunterschied\u201c f\u00fcr jedes Organ. Der Altersunterschied bezieht sich auf den Unterschied zwischen dem tats\u00e4chlichen Alter eines Organs und dem Alter, das auf der Grundlage der organspezifischen proteinbasierten Berechnungen des Algorithmus gesch\u00e4tzt wird. Die identifizierten Altersunterschiede, mit Ausnahme des Altersunterschieds im Darm, waren signifikant mit dem zuk\u00fcnftigen Risiko eines Todes jeglicher Ursache verbunden.<\/p>\n<p>Forscher sagten, dass ein Organ mit beschleunigter Alterung das Sterblichkeitsrisiko in den n\u00e4chsten 15 Jahren von 15% auf 50% erh\u00f6ht. Das Sterberisiko h\u00e4ngt vom betroffenen Organ ab.<\/p>\n<p>W\u00e4hrend eine beschleunigte Alterung des Herzens das Risiko einer Herzinsuffizienz um das 2,5-fache erh\u00f6hte, erh\u00f6hte die Alterung des Gehirns das Risiko eines kognitiven Verfalls um das 1,8-fache.<\/p>\n<p>Forscher sagen, wenn es in einer gr\u00f6\u00dferen Population \u00fcberpr\u00fcft w\u00fcrde, k\u00f6nnte es helfen, Organversagen und Krankheitsrisiko vorherzusagen, noch bevor Symptome auftreten.<\/p>\n<p>\u201eWenn wir diesen Befund bei 50.000 oder 100.000 Individuen reproduzieren k\u00f6nnen, bedeutet das, dass wir durch die \u00dcberwachung der Gesundheit einzelner Organe scheinbar gesunder Menschen m\u00f6glicherweise Organe finden k\u00f6nnen, die im K\u00f6rper der Menschen eine beschleunigte Alterung durchlaufen, und das k\u00f6nnte uns gelingen.\u201c Menschen zu behandeln, bevor sie krank werden\u201c, sagte Wyss-Coray.<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/people-above-50-may-have-accelerated-aging-least-1-organ-blood-test-could-detect-it-471176\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg\" class=\"ff-og-image-inserted\"><\/div>\n<p>Jedes Organ in unserem K\u00f6rper altert unterschiedlich schnell. Forscher sagen nun, dass etwa 18% gesunder Erwachsener \u00fcber 50 Jahren in mindestens einem ihrer Organe einer beschleunigten Alterung ausgesetzt sind.<\/p>\n<p>A <a rel=\"noopener nofollow\" href=\"https:\/\/www.nature.com\/articles\/s41586-023-06802-1\" target=\"_blank\">lernen<\/a>Die von Forschern der Stanford Medicine geleitete Studie legt nahe, dass es mit einem einfachen Bluttest m\u00f6glich sein k\u00f6nnte, eine beschleunigte Alterung eines Organs festzustellen, die das Krankheitsrisiko und die Mortalit\u00e4t erh\u00f6ht.<\/p>\n<p>\u201eWir k\u00f6nnen das biologische Alter eines Organs bei einem scheinbar gesunden Menschen absch\u00e4tzen. Das wiederum sagt das Risiko einer Person f\u00fcr Krankheiten im Zusammenhang mit diesem Organ voraus.\u201c <a rel=\"noopener nofollow\" href=\"https:\/\/www.eurekalert.org\/news-releases\/1009771\" target=\"_blank\">genannt<\/a> der leitende Autor der Studie, Tony Wyss-Coray.<\/p>\n<p>\u201eZahlreiche Studien haben einzelne Zahlen ermittelt, die das biologische Alter von Individuen darstellen \u2013 das Alter, das durch eine Reihe hochentwickelter Biomarker impliziert wird \u2013 im Gegensatz zu ihrem chronischen Alter, der tats\u00e4chlichen Anzahl der Jahre, die seit ihrer Geburt vergangen sind\u201c, sagte Wyss-Coray.<\/p>\n<p>Das Team ging jedoch noch einen Schritt weiter und ermittelte das biologische Alter jedes der 11 Schl\u00fcsselorgane und Organsysteme \u2013 Herz, Fett, Lunge, Immunsystem, Niere, Leber, Muskel, Bauchspeicheldr\u00fcse, Gehirn, Gef\u00e4\u00dfsystem und Darm.<\/p>\n<p>\u201eAls wir das biologische Alter jedes dieser Organe f\u00fcr jedes Individuum mit seinen Gegenst\u00fccken in einer gro\u00dfen Gruppe von Menschen ohne offensichtliche schwere Krankheiten verglichen, stellten wir fest, dass bei 18,41 TP3T der \u00fcber 50-J\u00e4hrigen mindestens ein Organ deutlich schneller alterte als das durchschnittlich\u201c, sagte Wyss-Coray.<\/p>\n<p>F\u00fcr die Studie wurden 5.678 Teilnehmer ausgewertet. Die Ergebnisse zeigten, dass nur bei einem von 60 Teilnehmern zwei Organe schneller alterten. Die beschleunigte Alterung zweier Organe erh\u00f6ht das Sterberisiko um das 6,5-fache.<\/p>\n<p>\u201eMithilfe kommerziell erh\u00e4ltlicher Technologien und eines von ihnen selbst entwickelten Algorithmus haben die Forscher die Konzentrationen Tausender Proteine im Blut von Menschen ermittelt, festgestellt, dass fast 1.000 dieser Proteine aus dem einen oder anderen einzelnen Organ stammen, und die abweichenden Konzentrationen dieser Proteine mit entsprechenden korrespondierenden Proteinen in Verbindung gebracht.\u201c \u201eDie beschleunigte Alterung der Organe und die Anf\u00e4lligkeit f\u00fcr Krankheiten und Mortalit\u00e4t\u201c, erkl\u00e4rten die Forscher.<\/p>\n<p>Das Forschungsteam sch\u00e4tzte einen \u201eAltersunterschied\u201c f\u00fcr jedes Organ. Der Altersunterschied bezieht sich auf den Unterschied zwischen dem tats\u00e4chlichen Alter eines Organs und dem Alter, das auf der Grundlage der organspezifischen proteinbasierten Berechnungen des Algorithmus gesch\u00e4tzt wird. Die identifizierten Altersunterschiede, mit Ausnahme des Altersunterschieds im Darm, waren signifikant mit dem zuk\u00fcnftigen Risiko eines Todes jeglicher Ursache verbunden.<\/p>\n<p>Forscher sagten, dass ein Organ mit beschleunigter Alterung das Sterblichkeitsrisiko in den n\u00e4chsten 15 Jahren von 15% auf 50% erh\u00f6ht. Das Sterberisiko h\u00e4ngt vom betroffenen Organ ab.<\/p>\n<p>W\u00e4hrend eine beschleunigte Alterung des Herzens das Risiko einer Herzinsuffizienz um das 2,5-fache erh\u00f6hte, erh\u00f6hte die Alterung des Gehirns das Risiko eines kognitiven Verfalls um das 1,8-fache.<\/p>\n<p>Forscher sagen, wenn es in einer gr\u00f6\u00dferen Population \u00fcberpr\u00fcft w\u00fcrde, k\u00f6nnte es helfen, Organversagen und Krankheitsrisiko vorherzusagen, noch bevor Symptome auftreten.<\/p>\n<p>\u201eWenn wir diesen Befund bei 50.000 oder 100.000 Individuen reproduzieren k\u00f6nnen, bedeutet das, dass wir durch die \u00dcberwachung der Gesundheit einzelner Organe scheinbar gesunder Menschen m\u00f6glicherweise Organe finden k\u00f6nnen, die im K\u00f6rper der Menschen eine beschleunigte Alterung durchlaufen, und das k\u00f6nnte uns gelingen.\u201c Menschen zu behandeln, bevor sie krank werden\u201c, sagte Wyss-Coray.<\/p>","protected":false},"author":2,"featured_media":9152,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-9151","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/menschen-uber-50-haben-moglicherweise-eine-beschleunigte-alterung-in-mindestens-einem-organ-ein-bluttest-konnte-dies-nachweisen\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality.&quot;We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person&#039;s risk for disease related to that organ,&quot; said the study&#039;s senior author, Tony Wyss-Coray.&quot;Numerous studies have come up with single numbers representing individuals&#039; biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth,&quot; Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine.&quot;When we compared each of these organs&#039; biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average,&quot; Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times.&quot;Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people&#039;s blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs&#039; accelerated aging and susceptibility to disease and mortality,&quot; the researchers explained.The research team estimated an &quot;age gap&quot; for each organ. Age gap refers to the difference between an organ&#039;s actual age and the age estimated based on the algorithm&#039;s organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear.&quot;If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people&#039;s bodies, and we might be able to treat people before they get sick,&quot; Wyss-Coray said.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/menschen-uber-50-haben-moglicherweise-eine-beschleunigte-alterung-in-mindestens-einem-organ-ein-bluttest-konnte-dies-nachweisen\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-07T08:54:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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Ein Bluttest k\u00f6nnte es erkennen \u2013 Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/de\/menschen-uber-50-haben-moglicherweise-eine-beschleunigte-alterung-in-mindestens-einem-organ-ein-bluttest-konnte-dies-nachweisen\/","og_locale":"de_DE","og_type":"article","og_title":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; A Blood Test Could Detect It - Urban Care Clinic","og_description":"Every organ in our body ages at a different pace. Researchers now say around 18% of healthy adults above the age of 50 face accelerated aging in at least one of their organs.A study, led by researchers from Stanford Medicine, suggests that with a simple blood test, it might be possible to detect accelerated aging of an organ that elevates disease risk and mortality.\"We can estimate the biological age of an organ in an apparently healthy person. That, in turn, predicts a person's risk for disease related to that organ,\" said the study's senior author, Tony Wyss-Coray.\"Numerous studies have come up with single numbers representing individuals' biological age \u2014 the age implied by a sophisticated array of biomarkers \u2014 as opposed to their chronical age, the actual numbers of years that have passed since their birth,\" Wyss-Coray said.However, the team took a step further by identifying the biological age of each of the 11 key organs and organ systems \u2013 heart, fat, lung, immune system, kidney, liver, muscle, pancreas, brain, vasculature, and intestine.\"When we compared each of these organs' biological age for each individual with its counterparts among a large group of people without obvious severe diseases, we found that 18.4% of those age 50 or older had at least one organ aging significantly more rapidly than the average,\" Wyss-Coray said.The study evaluated 5,678 participants. The results showed that only 1 in 60 participants had two organs aging at an accelerated rate. Accelerated aging of two organs raises the mortality risk by 6.5 times.\"Using commercially available technologies and an algorithm of their own design, the researchers assessed the levels of thousands of proteins in people's blood, determined that nearly 1,000 of those proteins originated within one or another single organ, and tied aberrant levels of those proteins to corresponding organs' accelerated aging and susceptibility to disease and mortality,\" the researchers explained.The research team estimated an \"age gap\" for each organ. Age gap refers to the difference between an organ's actual age and the age estimated based on the algorithm's organ-specific-protein-driven calculations. The identified age gaps, except that of intestine, were significantly associated with future risk of death from all causes.Having an accelerated aging organ raises the mortality risk from 15% to 50% over the next 15 years, researchers said. The mortality risk depends on the organ that was affected.While accelerated heart aging elevated heart failure risk by 2.5 times, brain aging raised the risk of cognitive decline by 1.8 times.Researchers say if verified in a larger population, it could help predict organ failure and disease risk even before symptoms appear.\"If we can reproduce this finding in 50,000 or 100,000 individuals, it will mean that by monitoring the health of individual organs in apparently healthy people, we might be able to find organs that are undergoing accelerated aging in people's bodies, and we might be able to treat people before they get sick,\" Wyss-Coray said.","og_url":"https:\/\/urbancare.clinic\/de\/menschen-uber-50-haben-moglicherweise-eine-beschleunigte-alterung-in-mindestens-einem-organ-ein-bluttest-konnte-dies-nachweisen\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-12-07T08:54:53+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/12\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it.jpg","width":1024,"height":1024,"type":"image\/jpeg"}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_misc":{"Verfasst von":"Urban Care Clinic","Gesch\u00e4tzte Lesezeit":"2\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/people-above-50-may-have-accelerated-aging-in-at-least-1-organ-a-blood-test-could-detect-it\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/a304a61bcf298680ee41e2e9ae193930"},"headline":"People Above 50 May Have Accelerated Aging In At Least 1 Organ; 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