{"id":8951,"date":"2023-11-27T13:00:27","date_gmt":"2023-11-27T10:00:27","guid":{"rendered":"https:\/\/urbancare.simplyit.solutions\/covid-19-booster-shot-study-says-half-dose-of-pfizer-vaccine-produces-strong-immune-response\/"},"modified":"2023-11-27T13:00:27","modified_gmt":"2023-11-27T10:00:27","slug":"eine-studie-zur-auffrischimpfung-gegen-covid-19-besagt-dass-die-halbe-dosis-des-pfizer-impfstoffs-eine-starke-immunantwort-hervorruft","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/covid-19-booster-shot-study-says-half-dose-of-pfizer-vaccine-produces-strong-immune-response\/","title":{"rendered":"COVID-19-Auffrischungsimpfung: Studie besagt, dass die halbe Dosis des Pfizer-Impfstoffs eine starke Immunantwort hervorruft"},"content":{"rendered":"
<\/div>\n

Eine neue Studie hat ergeben, dass die Einnahme einer reduzierten Dosis des Pfizer-COVID-19-Auffrischungsimpfstoffs eine \u00e4hnliche Immunantwort wie eine volle Dosis mit weniger Nebenwirkungen hervorruft.<\/p>\n

Forscher des Murdoch Children's Research Institute (MCRI) und des Nationalen Zentrums f\u00fcr \u00fcbertragbare Krankheiten in der Mongolei bewerteten die Immunantwort verschiedener COVID-19-Auffrischungsimpfungen, um zuk\u00fcnftige Impfstrategien festzulegen.<\/p>\n

Das Team stellte fest, dass Menschen, die zuvor die COVID-19-Impfstoffe von AstraZeneca oder Sinopharm erhalten hatten, eine \u201enicht minderwertige\u201c Immunantwort aufwiesen, wenn sie eine halbe Dosis eines Pfizer-COVID-19-Auffrischungsimpfstoffs erhielten, vergleichbar mit denen, die eine volle Dosis erhielten.<\/p>\n

Bei Erwachsenen, die den russischen COVID-19-Impfstoff Sputnik V erhielten, k\u00f6nnte die halbe Dosis jedoch weniger wirksam sein, wie die Studie ergab.<\/p>\n

\u201eDie Studie ergab, dass Teilnehmer, die eine halbe Dosis erhielten, weniger lokale Reaktionen berichteten als diejenigen, die die volle Dosis erhielten (60% gegen\u00fcber 72%), einschlie\u00dflich weniger Schmerzen und Druckempfindlichkeit. Sie berichteten auch \u00fcber weniger systemische Reaktionen (25% gegen\u00fcber 32%), darunter weniger Fieber, Erbrechen, Durchfall und Kopfschmerzen\u201c, sagten die Forscher in einem Pressemitteilung<\/a>.<\/p>\n

Die ersten Ergebnisse wurden in der Fachzeitschrift The Lancet Regional Health \u2013 Western Pacific ver\u00f6ffentlicht. An der Studie nahmen 601 erwachsene Teilnehmer aus der Mongolei teil. Ihre Immunantwort wurde 28 Tage nach der Impfung ausgewertet.<\/p>\n

\u201eEine fraktionierte Dosierung kann die Akzeptanz und Aufnahme von COVID-19-Boostern verbessern und die Kosten pro Dosis von COVID-19-Boosterprogrammen senken. Politische Entscheidungstr\u00e4ger und Impfberatungsaussch\u00fcsse k\u00f6nnen diese Daten nutzen, um flexible Entscheidungen \u00fcber Auffrischungspl\u00e4ne zu treffen\u201c, sagte MCRI-Professorin Kim Mulholland, die Teil der strategischen Beratergruppe der WHO f\u00fcr Impfungen war.<\/p>\n

Die Forscher werden nach sechs und zw\u00f6lf Monaten eine Nachuntersuchung durchf\u00fchren, um andere Aspekte der Immunantwort zu bewerten, einschlie\u00dflich der Rate nachlassender und durchbrechender Infektionen.<\/p>\n

\u201eDiese von CEPI finanzierte Studie hat wertvolle Daten \u00fcber Kombinationen von Impfstoffen generiert, die \u00fcber COVAX weit verbreitet sind und die dazu beitragen werden, zuk\u00fcnftige Auffrischungsstrategien in L\u00e4ndern im globalen S\u00fcden zu informieren.\u201c Eine fraktionierte Dosierung kann zu einem gleichberechtigten Zugang beitragen, indem sie Impfungen akzeptabler und kosteng\u00fcnstiger macht\u201c, sagte Dr. Melanie Saville, Gesch\u00e4ftsf\u00fchrerin f\u00fcr Forschung und Entwicklung bei The Coalition for Epidemic Preparedness Innovations (CEPI).<\/p>\n

Medizinische t\u00e4gliche Quelle<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Eine neue Studie hat ergeben, dass die Einnahme einer reduzierten Dosis des Pfizer-COVID-19-Auffrischungsimpfstoffs eine \u00e4hnliche Immunantwort wie eine volle Dosis mit weniger Nebenwirkungen hervorruft.<\/p>\n

Forscher des Murdoch Children's Research Institute (MCRI) und des Nationalen Zentrums f\u00fcr \u00fcbertragbare Krankheiten in der Mongolei bewerteten die Immunantwort verschiedener COVID-19-Auffrischungsimpfungen, um zuk\u00fcnftige Impfstrategien festzulegen.<\/p>\n

Das Team stellte fest, dass Menschen, die zuvor die COVID-19-Impfstoffe von AstraZeneca oder Sinopharm erhalten hatten, eine \u201enicht minderwertige\u201c Immunantwort aufwiesen, wenn sie eine halbe Dosis eines Pfizer-COVID-19-Auffrischungsimpfstoffs erhielten, vergleichbar mit denen, die eine volle Dosis erhielten.<\/p>\n

Bei Erwachsenen, die den russischen COVID-19-Impfstoff Sputnik V erhielten, k\u00f6nnte die halbe Dosis jedoch weniger wirksam sein, wie die Studie ergab.<\/p>\n

\u201eDie Studie ergab, dass Teilnehmer, die eine halbe Dosis erhielten, weniger lokale Reaktionen berichteten als diejenigen, die die volle Dosis erhielten (60% gegen\u00fcber 72%), einschlie\u00dflich weniger Schmerzen und Druckempfindlichkeit. Sie berichteten auch \u00fcber weniger systemische Reaktionen (25% gegen\u00fcber 32%), darunter weniger Fieber, Erbrechen, Durchfall und Kopfschmerzen\u201c, sagten die Forscher in einem Pressemitteilung<\/a>.<\/p>\n

Die ersten Ergebnisse wurden in der Fachzeitschrift The Lancet Regional Health \u2013 Western Pacific ver\u00f6ffentlicht. An der Studie nahmen 601 erwachsene Teilnehmer aus der Mongolei teil. Ihre Immunantwort wurde 28 Tage nach der Impfung ausgewertet.<\/p>\n

\u201eEine fraktionierte Dosierung kann die Akzeptanz und Aufnahme von COVID-19-Boostern verbessern und die Kosten pro Dosis von COVID-19-Boosterprogrammen senken. Politische Entscheidungstr\u00e4ger und Impfberatungsaussch\u00fcsse k\u00f6nnen diese Daten nutzen, um flexible Entscheidungen \u00fcber Auffrischungspl\u00e4ne zu treffen\u201c, sagte MCRI-Professorin Kim Mulholland, die Teil der strategischen Beratergruppe der WHO f\u00fcr Impfungen war.<\/p>\n

Die Forscher werden nach sechs und zw\u00f6lf Monaten eine Nachuntersuchung durchf\u00fchren, um andere Aspekte der Immunantwort zu bewerten, einschlie\u00dflich der Rate nachlassender und durchbrechender Infektionen.<\/p>\n

\u201eDiese von CEPI finanzierte Studie hat wertvolle Daten \u00fcber Kombinationen von Impfstoffen generiert, die \u00fcber COVAX weit verbreitet sind und die dazu beitragen werden, zuk\u00fcnftige Auffrischungsstrategien in L\u00e4ndern im globalen S\u00fcden zu informieren.\u201c Eine fraktionierte Dosierung kann zu einem gleichberechtigten Zugang beitragen, indem sie Impfungen akzeptabler und kosteng\u00fcnstiger macht\u201c, sagte Dr. Melanie Saville, Gesch\u00e4ftsf\u00fchrerin f\u00fcr Forschung und Entwicklung bei The Coalition for Epidemic Preparedness Innovations (CEPI).<\/p>","protected":false},"author":2,"featured_media":8952,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/11\/covid-19-booster-shot-study-says-half-dose-of-pfizer-vaccine-produces-strong-immune-response.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8951","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nCOVID-19 Booster Shot: Study Says Half Dose Of Pfizer Vaccine Produces Strong Immune Response - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/eine-studie-zur-auffrischimpfung-gegen-covid-19-besagt-dass-die-halbe-dosis-des-pfizer-impfstoffs-eine-starke-immunantwort-hervorruft\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"COVID-19 Booster Shot: Study Says Half Dose Of Pfizer Vaccine Produces Strong Immune Response - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Taking a reduced dose of the Pfizer COVID-19 booster vaccine produces a similar immune response as a full dose with fewer side effects, a new study has found.Researchers from Murdoch Children's Research Institute (MCRI) and the National Center for Communicable Diseases in Mongolia evaluated the immune response from different COVID-19 booster shots to determine future vaccination strategies.The team discovered that people who previously received AstraZeneca or Sinopharm COVID-19 vaccines had a "non-inferior" immune response when given a half dose of a Pfizer COVID-19 booster vaccine, comparable to those who received a full dose.However, in adults who received Russia's Sputnik V COVID-19 vaccine, the half-dose may be less effective, the study revealed."The study found half-dose boosted participants reported fewer local reactions than those receiving full doses (60% versus 72%) including less pain and tenderness. They also reported fewer systemic reactions (25% versus 32%) including fewer fevers, vomiting, diarrhea, and headaches," the researchers said in a news release.The first batch of the findings was published in the journal The Lancet Regional Health - Western Pacific. The study involved 601 adult participants from Mongolia. Their immune response was evaluated 28 days after vaccination."Fractional dosing may improve COVID-19 booster acceptability and uptake and reduce the per-dose cost of COVID-19 booster programs. Policymakers and immunization advisory committees can draw upon this data to make flexible boosting schedules decisions," said MCRI Professor Kim Mulholland, who was part of WHO's Strategic Advisory Group of Experts on Immunization.Researchers will conduct a follow-up at six and 12 months to evaluate other aspects of the immune response, including the rate of waning and breakthrough infections."This CEPI-funded study has generated valuable data about combinations of vaccines that have been widely distributed through COVAX, which will help to inform future booster strategies in countries in the global south. Fractional dosing can contribute to equitable access by making vaccination more acceptable and less costly," said Dr. Melanie Saville, executive director of R&D at The Coalition for Epidemic Preparedness Innovations (CEPI).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/eine-studie-zur-auffrischimpfung-gegen-covid-19-besagt-dass-die-halbe-dosis-des-pfizer-impfstoffs-eine-starke-immunantwort-hervorruft\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-11-27T10:00:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/11\/covid-19-booster-shot-study-says-half-dose-of-pfizer-vaccine-produces-strong-immune-response.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" 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or Sinopharm COVID-19 vaccines had a \"non-inferior\" immune response when given a half dose of a Pfizer COVID-19 booster vaccine, comparable to those who received a full dose.However, in adults who received Russia's Sputnik V COVID-19 vaccine, the half-dose may be less effective, the study revealed.\"The study found half-dose boosted participants reported fewer local reactions than those receiving full doses (60% versus 72%) including less pain and tenderness. They also reported fewer systemic reactions (25% versus 32%) including fewer fevers, vomiting, diarrhea, and headaches,\" the researchers said in a news release.The first batch of the findings was published in the journal The Lancet Regional Health - Western Pacific. The study involved 601 adult participants from Mongolia. Their immune response was evaluated 28 days after vaccination.\"Fractional dosing may improve COVID-19 booster acceptability and uptake and reduce the per-dose cost of COVID-19 booster programs. Policymakers and immunization advisory committees can draw upon this data to make flexible boosting schedules decisions,\" said MCRI Professor Kim Mulholland, who was part of WHO's Strategic Advisory Group of Experts on Immunization.Researchers will conduct a follow-up at six and 12 months to evaluate other aspects of the immune response, including the rate of waning and breakthrough infections.\"This CEPI-funded study has generated valuable data about combinations of vaccines that have been widely distributed through COVAX, which will help to inform future booster strategies in countries in the global south. 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