{"id":8588,"date":"2023-08-18T10:54:45","date_gmt":"2023-08-18T07:54:45","guid":{"rendered":"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/"},"modified":"2023-08-18T10:54:45","modified_gmt":"2023-08-18T07:54:45","slug":"ein-zur-gewichtsabnahme-verschriebenes-medikament-konnte-dazu-beitragen-das-assoziative-lernen-bei-menschen-mit-fettleibigkeit-zu-verbessern","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/ein-zur-gewichtsabnahme-verschriebenes-medikament-konnte-dazu-beitragen-das-assoziative-lernen-bei-menschen-mit-fettleibigkeit-zu-verbessern\/","title":{"rendered":"Ein zur Gewichtsreduktion verschriebenes Medikament k\u00f6nnte dazu beitragen, das assoziative Lernen bei Menschen mit Fettleibigkeit zu verbessern"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p>Eine aktuelle Studie ergab, dass ein Medikament, das zur Gewichtsreduktion und bei Typ-2-Diabetes verschrieben wird, das assoziative Lernen bei Menschen mit Fettleibigkeit verbessern kann.<\/p>\n<p>Assoziatives Lernen ist der Prozess, durch den Lebewesen etwas \u00fcber das lernen <a rel=\"noopener nofollow\" href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/associative-learning#:~:text=Associative%20learning%20is%20the%20process,unconscious%20recognition%20of%20a%20contingency.\" target=\"_blank\">Verbindungen<\/a> zwischen den Dingen, die um sie herum passieren. Dabei geht es sowohl um die Ver\u00e4nderung bestehender Verhaltensweisen als auch um die Entwicklung neuer Verhaltensweisen.<\/p>\n<p>Forscher des Max-Planck-Instituts f\u00fcr Stoffwechselforschung untersuchten, wie sich assoziatives Lernen bei Menschen mit eingeschr\u00e4nkter Insulinsensitivit\u00e4t im Zusammenhang mit Fettleibigkeit ver\u00e4ndert. Sie untersuchten das damit verbundene Lernverhalten bei zwei Teilnehmergruppen; einer mit normalem Gewicht, der eine hohe Insulinsensitivit\u00e4t aufwies, und der andere mit einer aufgrund von Fettleibigkeit verringerten Insulinsensitivit\u00e4t. Das Team stellte fest, dass eine verringerte Insulinsensitivit\u00e4t aufgrund von Fettleibigkeit das assoziative Lernen beeintr\u00e4chtigt.<\/p>\n<p>Den Teilnehmern der adip\u00f6sen Gruppe wurde entweder ein Placebo oder Liraglutid verabreicht \u2013 ein <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/doctors-worry-ozempic-causes-spike-er-visits-470230\">Medikament zur Gewichtsabnahme<\/a> verschrieben bei Fettleibigkeit und Typ-2-Diabetes.<\/p>\n<p>Mit einer Einzeldosis Liraglutid kann die Beeintr\u00e4chtigung des assoziativen Lernens bei \u00fcbergewichtigen Menschen r\u00fcckg\u00e4ngig gemacht und auf das gleiche Niveau wie bei Menschen mit Normalgewicht gebracht werden, so die in der Fachzeitschrift Nature Metabolism ver\u00f6ffentlichten Ergebnisse.<\/p>\n<p>\u201eDiese Erkenntnisse sind von grundlegender Bedeutung. Wir zeigen hier, dass grundlegende Verhaltensweisen wie assoziatives Lernen nicht nur von \u00e4u\u00dferen Umweltbedingungen, sondern auch vom Stoffwechselzustand des K\u00f6rpers abh\u00e4ngen. Ob jemand \u00fcbergewichtig ist oder nicht, bestimmt also auch, wie das Gehirn lernt, Sinnessignale zu assoziieren und welche Motivation entsteht. \u201eDie Normalisierung, die wir mit dem Medikament bei Menschen mit Adipositas erreicht haben, passt daher zu Studien, die zeigen, dass diese Medikamente ein normales S\u00e4ttigungsgef\u00fchl wiederherstellen, was dazu f\u00fchrt, dass Menschen weniger essen und dadurch Gewicht verlieren\u201c, sagte Studienleiter Marc Tittgemeyer in einer Stellungnahme <a rel=\"noopener nofollow\" href=\"https:\/\/www.eurekalert.org\/news-releases\/998604\" target=\"_blank\">Pressemitteilung<\/a>.<\/p>\n<p>Die Studie zeigt, wie Fettleibigkeit das Gehirn ver\u00e4ndern kann und wie der Prozess mit Medikamenten ver\u00e4ndert werden kann. Die Forscher planen, weitere Studien durchzuf\u00fchren, um zu verstehen, wie Liraglutid bei a wirkt <a rel=\"noopener nofollow\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/anti-obesity-drug-improves-associative-learning-in-people-with-obesity#Wide-range-of-options-for-treating-obesity\" target=\"_blank\">Molekulare Ebene<\/a>. Sie planen auch zu untersuchen, ob andere Ans\u00e4tze wie Gewichtsverlustversuche und Insulinsensibilisatoren \u00e4hnliche Verbesserungen bringen k\u00f6nnen.<\/p>\n<p>\u201eW\u00e4hrend es ermutigend ist, dass verf\u00fcgbare Medikamente einen positiven Effekt auf die Gehirnaktivit\u00e4t bei Adipositas haben, ist es alarmierend, dass es auch bei jungen Menschen mit Adipositas und ohne andere Erkrankungen zu Ver\u00e4nderungen der Gehirnleistung kommt. Die Pr\u00e4vention von Adipositas sollte in unserem Gesundheitssystem in Zukunft eine viel gr\u00f6\u00dfere Rolle spielen. \u201eLebenslange Medikamente sind im Vergleich zur Prim\u00e4rpr\u00e4vention von Adipositas und damit verbundenen Komplikationen die weniger bevorzugte Option\u201c, sagte Ruth Han\u00dfen, Erstautorin der Studie und \u00c4rztin an der Universit\u00e4tsklinik K\u00f6ln.<\/p>\n<p>Ver\u00f6ffentlicht von Medicaldaily.com<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/drug-prescribed-weight-loss-could-help-improve-associative-learning-people-obesity-470681\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" class=\"ff-og-image-inserted\"><\/div>\n<p>Eine aktuelle Studie ergab, dass ein Medikament, das zur Gewichtsreduktion und bei Typ-2-Diabetes verschrieben wird, das assoziative Lernen bei Menschen mit Fettleibigkeit verbessern kann.<\/p>\n<p>Assoziatives Lernen ist der Prozess, durch den Lebewesen etwas \u00fcber das lernen <a rel=\"noopener nofollow\" href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/associative-learning#:~:text=Associative%20learning%20is%20the%20process,unconscious%20recognition%20of%20a%20contingency.\" target=\"_blank\">Verbindungen<\/a> zwischen den Dingen, die um sie herum passieren. Dabei geht es sowohl um die Ver\u00e4nderung bestehender Verhaltensweisen als auch um die Entwicklung neuer Verhaltensweisen.<\/p>\n<p>Forscher des Max-Planck-Instituts f\u00fcr Stoffwechselforschung untersuchten, wie sich assoziatives Lernen bei Menschen mit eingeschr\u00e4nkter Insulinsensitivit\u00e4t im Zusammenhang mit Fettleibigkeit ver\u00e4ndert. Sie untersuchten das damit verbundene Lernverhalten bei zwei Teilnehmergruppen; einer mit normalem Gewicht, der eine hohe Insulinsensitivit\u00e4t aufwies, und der andere mit einer aufgrund von Fettleibigkeit verringerten Insulinsensitivit\u00e4t. Das Team stellte fest, dass eine verringerte Insulinsensitivit\u00e4t aufgrund von Fettleibigkeit das assoziative Lernen beeintr\u00e4chtigt.<\/p>\n<p>Den Teilnehmern der adip\u00f6sen Gruppe wurde entweder ein Placebo oder Liraglutid verabreicht \u2013 ein <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/doctors-worry-ozempic-causes-spike-er-visits-470230\">Medikament zur Gewichtsabnahme<\/a> verschrieben bei Fettleibigkeit und Typ-2-Diabetes.<\/p>\n<p>Mit einer Einzeldosis Liraglutid kann die Beeintr\u00e4chtigung des assoziativen Lernens bei \u00fcbergewichtigen Menschen r\u00fcckg\u00e4ngig gemacht und auf das gleiche Niveau wie bei Menschen mit Normalgewicht gebracht werden, so die in der Fachzeitschrift Nature Metabolism ver\u00f6ffentlichten Ergebnisse.<\/p>\n<p>\u201eDiese Erkenntnisse sind von grundlegender Bedeutung. Wir zeigen hier, dass grundlegende Verhaltensweisen wie assoziatives Lernen nicht nur von \u00e4u\u00dferen Umweltbedingungen, sondern auch vom Stoffwechselzustand des K\u00f6rpers abh\u00e4ngen. Ob jemand \u00fcbergewichtig ist oder nicht, bestimmt also auch, wie das Gehirn lernt, Sinnessignale zu assoziieren und welche Motivation entsteht. \u201eDie Normalisierung, die wir mit dem Medikament bei Menschen mit Adipositas erreicht haben, passt daher zu Studien, die zeigen, dass diese Medikamente ein normales S\u00e4ttigungsgef\u00fchl wiederherstellen, was dazu f\u00fchrt, dass Menschen weniger essen und dadurch Gewicht verlieren\u201c, sagte Studienleiter Marc Tittgemeyer in einer Stellungnahme <a rel=\"noopener nofollow\" href=\"https:\/\/www.eurekalert.org\/news-releases\/998604\" target=\"_blank\">Pressemitteilung<\/a>.<\/p>\n<p>Die Studie zeigt, wie Fettleibigkeit das Gehirn ver\u00e4ndern kann und wie der Prozess mit Medikamenten ver\u00e4ndert werden kann. Die Forscher planen, weitere Studien durchzuf\u00fchren, um zu verstehen, wie Liraglutid bei a wirkt <a rel=\"noopener nofollow\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/anti-obesity-drug-improves-associative-learning-in-people-with-obesity#Wide-range-of-options-for-treating-obesity\" target=\"_blank\">Molekulare Ebene<\/a>. Sie planen auch zu untersuchen, ob andere Ans\u00e4tze wie Gewichtsverlustversuche und Insulinsensibilisatoren \u00e4hnliche Verbesserungen bringen k\u00f6nnen.<\/p>\n<p>\u201eW\u00e4hrend es ermutigend ist, dass verf\u00fcgbare Medikamente einen positiven Effekt auf die Gehirnaktivit\u00e4t bei Adipositas haben, ist es alarmierend, dass es auch bei jungen Menschen mit Adipositas und ohne andere Erkrankungen zu Ver\u00e4nderungen der Gehirnleistung kommt. Die Pr\u00e4vention von Adipositas sollte in unserem Gesundheitssystem in Zukunft eine viel gr\u00f6\u00dfere Rolle spielen. \u201eLebenslange Medikamente sind im Vergleich zur Prim\u00e4rpr\u00e4vention von Adipositas und damit verbundenen Komplikationen die weniger bevorzugte Option\u201c, sagte Ruth Han\u00dfen, Erstautorin der Studie und \u00c4rztin an der Universit\u00e4tsklinik K\u00f6ln.<\/p>\n<p>Ver\u00f6ffentlicht von Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8589,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8588","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/ein-zur-gewichtsabnahme-verschriebenes-medikament-konnte-dazu-beitragen-das-assoziative-lernen-bei-menschen-mit-fettleibigkeit-zu-verbessern\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A drug prescribed for weight loss and type 2 diabetes may improve associative learning in people with obesity, a recent study has found.Associative learning is the process by which living things learn about the connections between things happening around them. It involves both modifications of existing behaviors and the development of new behaviors.Researchers from Max Planck Institute for Metabolism Research evaluated how associative learning changes in people with impaired insulin sensitivity associated with obesity. They studied associated learning behaviors in two groups of participants; one with normal weight, who had high insulin sensitivity, and the other with reduced insulin sensitivity from obesity. The team found that reduced insulin sensitivity from obesity impairs associative learning.The participants in the obese group were either given a placebo or liraglutide \u2013 a weight loss drug prescribed for obesity and type 2 diabetes.With a single dose of liraglutide, the impaired associative learning in obese people can be reversed and brought back to the levels same as that of people with normal weight, according to the findings, published in the journal Nature Metabolism.&quot;These findings are of fundamental importance. We show here that basic behaviors such as associative learning depend not only on external environmental conditions but also on the body&#039;s metabolic state. So, whether someone has overweight or not also determines how the brain learns to associate sensory signals and what motivation is generated. The normalization we achieved with the drug in subjects with obesity, therefore, fits with studies showing that these drugs restore a normal feeling of satiety, causing people to eat less and therefore lose weight,&quot; study leader Marc Tittgemeyer said in a news release.The study shows how obesity can alter the brain and how the process can be modified with medication. The researchers plan to carry out further studies to understand how liraglutide works at a molecular level. They also plan to explore if other approaches such as weight loss trials and insulin sensitizers can also bring in similar improvements.&quot;While it is encouraging that available drugs have a positive effect on brain activity in obesity, it is alarming that changes in brain performance occur even in young people with obesity without other medical conditions. Obesity prevention should play a much greater role in our healthcare system in the future. Lifelong medication is the less preferred option in comparison to primary prevention of obesity and associated complications,&quot; said Ruth Han\u00dfen, first author of the study and a physician at the University Hospital of Cologne.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/ein-zur-gewichtsabnahme-verschriebenes-medikament-konnte-dazu-beitragen-das-assoziative-lernen-bei-menschen-mit-fettleibigkeit-zu-verbessern\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-08-18T07:54:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity\",\"datePublished\":\"2023-08-18T07:54:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\"},\"wordCount\":438,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\",\"url\":\"https:\/\/urbancare.clinic\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity\/\",\"name\":\"A Drug Prescribed For Weight Loss Could Help Improve Associative Learning In People With Obesity - 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Urban Care Clinic","og_description":"A drug prescribed for weight loss and type 2 diabetes may improve associative learning in people with obesity, a recent study has found.Associative learning is the process by which living things learn about the connections between things happening around them. It involves both modifications of existing behaviors and the development of new behaviors.Researchers from Max Planck Institute for Metabolism Research evaluated how associative learning changes in people with impaired insulin sensitivity associated with obesity. They studied associated learning behaviors in two groups of participants; one with normal weight, who had high insulin sensitivity, and the other with reduced insulin sensitivity from obesity. The team found that reduced insulin sensitivity from obesity impairs associative learning.The participants in the obese group were either given a placebo or liraglutide \u2013 a weight loss drug prescribed for obesity and type 2 diabetes.With a single dose of liraglutide, the impaired associative learning in obese people can be reversed and brought back to the levels same as that of people with normal weight, according to the findings, published in the journal Nature Metabolism.\"These findings are of fundamental importance. We show here that basic behaviors such as associative learning depend not only on external environmental conditions but also on the body's metabolic state. So, whether someone has overweight or not also determines how the brain learns to associate sensory signals and what motivation is generated. The normalization we achieved with the drug in subjects with obesity, therefore, fits with studies showing that these drugs restore a normal feeling of satiety, causing people to eat less and therefore lose weight,\" study leader Marc Tittgemeyer said in a news release.The study shows how obesity can alter the brain and how the process can be modified with medication. The researchers plan to carry out further studies to understand how liraglutide works at a molecular level. They also plan to explore if other approaches such as weight loss trials and insulin sensitizers can also bring in similar improvements.\"While it is encouraging that available drugs have a positive effect on brain activity in obesity, it is alarming that changes in brain performance occur even in young people with obesity without other medical conditions. Obesity prevention should play a much greater role in our healthcare system in the future. Lifelong medication is the less preferred option in comparison to primary prevention of obesity and associated complications,\" said Ruth Han\u00dfen, first author of the study and a physician at the University Hospital of Cologne.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/de\/ein-zur-gewichtsabnahme-verschriebenes-medikament-konnte-dazu-beitragen-das-assoziative-lernen-bei-menschen-mit-fettleibigkeit-zu-verbessern\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-08-18T07:54:45+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/08\/a-drug-prescribed-for-weight-loss-could-help-improve-associative-learning-in-people-with-obesity.jpg","type":"","width":"","height":""}],"author":"Urban Care 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