{"id":8496,"date":"2023-07-18T10:56:23","date_gmt":"2023-07-18T07:56:23","guid":{"rendered":"https:\/\/urbancare.clinic\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails\/"},"modified":"2023-07-18T10:56:23","modified_gmt":"2023-07-18T07:56:23","slug":"einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren\/","title":{"rendered":"Ein Schritt n\u00e4her an einer Anti-Aging-Pille? Harvard-Forscher finden chemische Cocktails, die das Alter umkehren"},"content":{"rendered":"
<\/div>\n

Wissenschaftler sind in einem Wettlauf um die Suche nach einer \u201eJungbrunnen\u201c-Pille, die das Potenzial hat, die Lebenserwartung zu verl\u00e4ngern oder den Alterungsprozess umzukehren. Sind wir schon da? Es sieht so aus, als w\u00e4ren wir dem ewig schwer fassbaren Lebenselixier einen Schritt n\u00e4her gekommen.<\/p>\n

In einer m\u00f6glicherweise bahnbrechenden Entdeckung hat eine Gruppe von Forschern aus Harvard sechs chemische Cocktails identifiziert, von denen sie sagen, dass sie den Alterungsprozess in Hautzellen von Menschen und M\u00e4usen umkehren k\u00f6nnen.<\/p>\n

\u201eWir sind dankbar, dass wir unsere neueste Ver\u00f6ffentlichung ver\u00f6ffentlichen d\u00fcrfen: Wir haben zuvor gezeigt, dass eine Altersumkehr durch die Aktivierung embryonaler Gene durch Gentherapie m\u00f6glich ist.\u201c Jetzt zeigen wir, dass es mit chemischen Cocktails m\u00f6glich ist, ein Schritt in Richtung einer erschwinglichen Ganzk\u00f6rperverj\u00fcngung\u201c, twitterte Dr. David Sinclair, Molekularbiologe an der Harvard Medical School und Mitautor der Studie.<\/p>\n

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Wir freuen uns, unsere neueste Ver\u00f6ffentlichung mit Ihnen teilen zu d\u00fcrfen: Wir haben bereits zuvor gezeigt, dass eine Altersumkehr durch die Aktivierung embryonaler Gene durch Gentherapie m\u00f6glich ist. Jetzt zeigen wir, dass es mit chemischen Cocktails m\u00f6glich ist, ein Schritt in Richtung einer erschwinglichen Ganzk\u00f6rperverj\u00fcngung 1\/17 https:\/\/t.co\/J9c01lv5FQ<\/a><\/p>\n

\u2014 David Sinclair (@davidasinclair) 12. Juli 2023<\/a><\/p><\/blockquote>\n<\/div>\n<\/div>\n<\/figure>\n

\u201eWir identifizieren sechs chemische Cocktails, die in weniger als einer Woche und ohne Beeintr\u00e4chtigung der zellul\u00e4ren Identit\u00e4t ein jugendliches genomweites Transkriptprofil und ein umgekehrtes transkriptomisches Alter wiederherstellen.\u201c Somit kann eine Verj\u00fcngung durch Altersumkehr nicht nur durch genetische, sondern auch chemische Mittel erreicht werden\u201c, schreiben die Forscher in der in der Fachzeitschrift Aging ver\u00f6ffentlichten Studie.<\/p>\n

Die Studie bewertete die Auswirkungen von a Drogengebr\u00e4u<\/a> das das Wachstumshormon Metformin und ein Medikament enth\u00e4lt, das die enzymaktivierte Proteinkinase (AMPK) bei der Verj\u00fcngung gealterter Muskeln, Lebergewebe und anderer Organe aktiviert.<\/p>\n

\u201eStudien am Sehnerv, Gehirngewebe, Niere und Muskel haben vielversprechende Ergebnisse gezeigt, mit verbesserter Sehkraft und verl\u00e4ngerter Lebensdauer bei M\u00e4usen und k\u00fcrzlich, im April dieses Jahres, verbesserter Sehkraft bei Affen\u201c, sagte Dr. Sinclair genannt<\/a>.<\/p>\n

Das Team behauptete, bei allen sechs Kombinationen altersumkehrende Effekte festgestellt zu haben. Die Wirkung einer viert\u00e4gigen Behandlung mit den Cocktails war vergleichbar mit der Gesamtver\u00e4nderung, die nach einem Jahr einer regenerativen Behandlung in einer wegweisenden Studie aus dem Jahr 2019 beobachtet wurde.<\/p>\n

\u201eDiese neue Entdeckung bietet das Potenzial, das Altern mit einer einzigen Pille umzukehren, mit Anwendungen, die von der Verbesserung der Sehkraft bis zur wirksamen Behandlung altersbedingter Krankheiten reichen\u201c, f\u00fcgte Dr. Sinclair hinzu.<\/p>\n

Allerdings stehen einige Forscher den Ergebnissen mit einer Prise Skepsis gegen\u00fcber. Matt Kaeberlein, ein Biogerontologe, erz\u00e4hlte Erde<\/a> dass es sich nur um eine vorl\u00e4ufige Studie handelt und die Forscher mindestens eine der Zubereitungen in einem Tiermodell auf ihre Wirksamkeit bei altersbezogenen Gesundheitsmetriken oder der Lebensdauer validieren sollten.<\/p>\n

Dr. Charles Brenner, ein Stoffwechselforscher, \u00e4u\u00dferte Bedenken hinsichtlich der Sicherheit der in den Cocktails verwendeten Medikamente. \u201eDiese sind im Allgemeinen allein oder in Kombination nicht sicher\u201c, sagte Brenner.<\/p>\n

Ver\u00f6ffentlicht von Medicaldaily.com<\/p>\n

Medizinische t\u00e4gliche Quelle<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

<\/div>\n

Wissenschaftler sind in einem Wettlauf um die Suche nach einer \u201eJungbrunnen\u201c-Pille, die das Potenzial hat, die Lebenserwartung zu verl\u00e4ngern oder den Alterungsprozess umzukehren. Sind wir schon da? Es sieht so aus, als w\u00e4ren wir dem ewig schwer fassbaren Lebenselixier einen Schritt n\u00e4her gekommen.<\/p>\n

In einer m\u00f6glicherweise bahnbrechenden Entdeckung hat eine Gruppe von Forschern aus Harvard sechs chemische Cocktails identifiziert, von denen sie sagen, dass sie den Alterungsprozess in Hautzellen von Menschen und M\u00e4usen umkehren k\u00f6nnen.<\/p>\n

\u201eWir sind dankbar, dass wir unsere neueste Ver\u00f6ffentlichung ver\u00f6ffentlichen d\u00fcrfen: Wir haben zuvor gezeigt, dass eine Altersumkehr durch die Aktivierung embryonaler Gene durch Gentherapie m\u00f6glich ist.\u201c Jetzt zeigen wir, dass es mit chemischen Cocktails m\u00f6glich ist, ein Schritt in Richtung einer erschwinglichen Ganzk\u00f6rperverj\u00fcngung\u201c, twitterte Dr. David Sinclair, Molekularbiologe an der Harvard Medical School und Mitautor der Studie.<\/p>\n

\n
\n
\n
\n

Wir freuen uns, unsere neueste Ver\u00f6ffentlichung mit Ihnen teilen zu d\u00fcrfen: Wir haben bereits zuvor gezeigt, dass eine Altersumkehr durch die Aktivierung embryonaler Gene durch Gentherapie m\u00f6glich ist. Jetzt zeigen wir, dass es mit chemischen Cocktails m\u00f6glich ist, ein Schritt in Richtung einer erschwinglichen Ganzk\u00f6rperverj\u00fcngung 1\/17 https:\/\/t.co\/J9c01lv5FQ<\/a><\/p>\n

\u2014 David Sinclair (@davidasinclair) 12. Juli 2023<\/a><\/p><\/blockquote>\n<\/div>\n<\/div>\n<\/figure>\n

\u201eWir identifizieren sechs chemische Cocktails, die in weniger als einer Woche und ohne Beeintr\u00e4chtigung der zellul\u00e4ren Identit\u00e4t ein jugendliches genomweites Transkriptprofil und ein umgekehrtes transkriptomisches Alter wiederherstellen.\u201c Somit kann eine Verj\u00fcngung durch Altersumkehr nicht nur durch genetische, sondern auch chemische Mittel erreicht werden\u201c, schreiben die Forscher in der in der Fachzeitschrift Aging ver\u00f6ffentlichten Studie.<\/p>\n

Die Studie bewertete die Auswirkungen von a Drogengebr\u00e4u<\/a> das das Wachstumshormon Metformin und ein Medikament enth\u00e4lt, das die enzymaktivierte Proteinkinase (AMPK) bei der Verj\u00fcngung gealterter Muskeln, Lebergewebe und anderer Organe aktiviert.<\/p>\n

\u201eStudien am Sehnerv, Gehirngewebe, Niere und Muskel haben vielversprechende Ergebnisse gezeigt, mit verbesserter Sehkraft und verl\u00e4ngerter Lebensdauer bei M\u00e4usen und k\u00fcrzlich, im April dieses Jahres, verbesserter Sehkraft bei Affen\u201c, sagte Dr. Sinclair genannt<\/a>.<\/p>\n

Das Team behauptete, bei allen sechs Kombinationen altersumkehrende Effekte festgestellt zu haben. Die Wirkung einer viert\u00e4gigen Behandlung mit den Cocktails war vergleichbar mit der Gesamtver\u00e4nderung, die nach einem Jahr einer regenerativen Behandlung in einer wegweisenden Studie aus dem Jahr 2019 beobachtet wurde.<\/p>\n

\u201eDiese neue Entdeckung bietet das Potenzial, das Altern mit einer einzigen Pille umzukehren, mit Anwendungen, die von der Verbesserung der Sehkraft bis zur wirksamen Behandlung altersbedingter Krankheiten reichen\u201c, f\u00fcgte Dr. Sinclair hinzu.<\/p>\n

Allerdings stehen einige Forscher den Ergebnissen mit einer Prise Skepsis gegen\u00fcber. Matt Kaeberlein, ein Biogerontologe, erz\u00e4hlte Erde<\/a> dass es sich nur um eine vorl\u00e4ufige Studie handelt und die Forscher mindestens eine der Zubereitungen in einem Tiermodell auf ihre Wirksamkeit bei altersbezogenen Gesundheitsmetriken oder der Lebensdauer validieren sollten.<\/p>\n

Dr. Charles Brenner, ein Stoffwechselforscher, \u00e4u\u00dferte Bedenken hinsichtlich der Sicherheit der in den Cocktails verwendeten Medikamente. \u201eDiese sind im Allgemeinen allein oder in Kombination nicht sicher\u201c, sagte Brenner.<\/p>\n

Ver\u00f6ffentlicht von Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8497,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8496","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nA Step Closer To An Anti-Aging Pill? Harvard Researchers Find Age-Reversing Chemical Cocktails - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Step Closer To An Anti-Aging Pill? Harvard Researchers Find Age-Reversing Chemical Cocktails - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Scientists have been in a race to find a "fountain of youth" pill that has the potential to increase longevity or reverse aging. Are we there yet? Looks like we are a step closer to the ever-elusive elixir of life.In what could be a groundbreaking discovery, a group of researchers from Harvard has identified six chemical cocktails that they say can reverse the aging process in both human and mouse skin cells."Grateful to share our latest publication: We've previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it's possible with chemical cocktails, a step towards affordable whole-body rejuvenation," tweeted Dr. David Sinclair, a molecular biologist at Harvard Medical School and co-author of the study.Grateful to share our latest publication: We\u2019ve previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it\u2019s possible with chemical cocktails, a step towards affordable whole-body rejuvenation 1\/17 https:\/\/t.co\/J9c01lv5FQ\u2014 David Sinclair (@davidasinclair) July 12, 2023 "We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means, " the researchers wrote in the study published in the journal Aging.The study evaluated the impact of a drug concoction that contains the growth hormone metformin and a drug that activates the enzyme-activated protein kinase (AMPK) in the rejuvenation of aged muscles, liver tissue and other organs."Studies on the optic nerve, brain tissue, kidney and muscle have shown promising results, with improved vision and extended lifespan in mice and, recently, in April of this year, improved vision in monkeys," Dr. Sinclair said.The team claimed they found age-reversing effects with all six combinations. The impact of a four-day treatment using the cocktails was comparable to the total change seen after a year of a regenerative treatment in a landmark study from 2019."This new discovery offers the potential to reverse aging with a single pill, with applications ranging from improving eyesight to effectively treating age-related diseases," Dr. Sinclair added.However, some researchers receive the findings with a pinch of skepticism. Matt Kaeberlein, a biogerontologist, told Earth that it is just a preliminary study and the researchers should validate at least one of the concoctions in an animal model for its effectiveness in age-related health metrics or lifespan.Dr. Charles Brenner, a metabolism researcher, raised concerns about the safety of the drugs used in the cocktails. "These are generally not safe alone or in a combination," Brenner said.Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-18T07:56:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"A Step Closer To An Anti-Aging Pill? 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Harvard-Forscher finden chemische Cocktails, die das Alter umkehren \u2013 Urban Care Clinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/urbancare.clinic\/de\/einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren\/","og_locale":"de_DE","og_type":"article","og_title":"A Step Closer To An Anti-Aging Pill? Harvard Researchers Find Age-Reversing Chemical Cocktails - Urban Care Clinic","og_description":"Scientists have been in a race to find a \"fountain of youth\" pill that has the potential to increase longevity or reverse aging. Are we there yet? Looks like we are a step closer to the ever-elusive elixir of life.In what could be a groundbreaking discovery, a group of researchers from Harvard has identified six chemical cocktails that they say can reverse the aging process in both human and mouse skin cells.\"Grateful to share our latest publication: We've previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it's possible with chemical cocktails, a step towards affordable whole-body rejuvenation,\" tweeted Dr. David Sinclair, a molecular biologist at Harvard Medical School and co-author of the study.Grateful to share our latest publication: We\u2019ve previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it\u2019s possible with chemical cocktails, a step towards affordable whole-body rejuvenation 1\/17 https:\/\/t.co\/J9c01lv5FQ\u2014 David Sinclair (@davidasinclair) July 12, 2023 \"We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means, \" the researchers wrote in the study published in the journal Aging.The study evaluated the impact of a drug concoction that contains the growth hormone metformin and a drug that activates the enzyme-activated protein kinase (AMPK) in the rejuvenation of aged muscles, liver tissue and other organs.\"Studies on the optic nerve, brain tissue, kidney and muscle have shown promising results, with improved vision and extended lifespan in mice and, recently, in April of this year, improved vision in monkeys,\" Dr. Sinclair said.The team claimed they found age-reversing effects with all six combinations. The impact of a four-day treatment using the cocktails was comparable to the total change seen after a year of a regenerative treatment in a landmark study from 2019.\"This new discovery offers the potential to reverse aging with a single pill, with applications ranging from improving eyesight to effectively treating age-related diseases,\" Dr. Sinclair added.However, some researchers receive the findings with a pinch of skepticism. Matt Kaeberlein, a biogerontologist, told Earth that it is just a preliminary study and the researchers should validate at least one of the concoctions in an animal model for its effectiveness in age-related health metrics or lifespan.Dr. Charles Brenner, a metabolism researcher, raised concerns about the safety of the drugs used in the cocktails. \"These are generally not safe alone or in a combination,\" Brenner said.Published by Medicaldaily.com","og_url":"https:\/\/urbancare.clinic\/de\/einen-schritt-naher-an-einer-anti-aging-pille-harvard-forscher-finden-chemische-cocktails-die-das-alter-umkehren\/","og_site_name":"Urban Care Clinic","article_publisher":"https:\/\/www.facebook.com\/urbancarezanzibar","article_published_time":"2023-07-18T07:56:23+00:00","og_image":[{"url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails.jpg","type":"","width":"","height":""}],"author":"Urban Care Clinic","twitter_card":"summary_large_image","twitter_image":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/07\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails.jpg","twitter_misc":{"Verfasst von":"Urban Care Clinic","Gesch\u00e4tzte Lesezeit":"2\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/urbancare.clinic\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails\/#article","isPartOf":{"@id":"https:\/\/urbancare.clinic\/a-step-closer-to-an-anti-aging-pill-harvard-researchers-find-age-reversing-chemical-cocktails\/"},"author":{"name":"Urban Care Clinic","@id":"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c"},"headline":"A Step Closer To An Anti-Aging Pill? 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