{"id":8303,"date":"2023-06-06T09:32:34","date_gmt":"2023-06-06T06:32:34","guid":{"rendered":"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/"},"modified":"2023-06-06T09:32:34","modified_gmt":"2023-06-06T06:32:34","slug":"studie-zur-hormonersatztherapie-besagt-dass-die-einnahme-von-oralem-ostrogen-das-risiko-fur-bluthochdruck-erhoht","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/studie-zur-hormonersatztherapie-besagt-dass-die-einnahme-von-oralem-ostrogen-das-risiko-fur-bluthochdruck-erhoht\/","title":{"rendered":"Hormonersatztherapie: Studie besagt, dass die Einnahme von oralem \u00d6strogen das Risiko f\u00fcr Bluthochdruck erh\u00f6ht"},"content":{"rendered":"<p>Frauen, die im Rahmen ihrer Hormontherapie in den Wechseljahren \u00d6strogentabletten einnehmen, haben ein h\u00f6heres Risiko, an Bluthochdruck zu erkranken, wie eine aktuelle Studie ergab.<\/p>\n<p>Wenn eine Frau in die Wechseljahre kommt, produzieren ihre Eierst\u00f6cke nicht mehr wie zuvor hohe Mengen an \u00d6strogen und Progesteron. Dieser pl\u00f6tzliche Hormonabfall verursacht verschiedene Beschwerden wie Hitzewallungen, Nachtschwei\u00df, Stimmungsschwankungen und Schlafst\u00f6rungen.<\/p>\n<p>Frauen in den Wechseljahren wird h\u00e4ufig eine Hormonersatztherapie empfohlen, um die Symptome zu lindern und das Risiko von Osteoporose und Herz-Kreislauf-Erkrankungen, die mit dem Hormonabfall einhergehen, zu verringern.<\/p>\n<p>Es gibt zwei Haupttypen von h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">Ormon-Ersatztherapien<\/a> \u2013 \u00d6strogentherapie und \u00d6strogen-Progesteron\/Gestagen-Hormontherapie (EPT).<\/p>\n<p>Bei der \u00d6strogentherapie wird \u00d6strogen in Form einer Pille, eines Pflasters, einer Creme, eines Vaginalrings, eines Gels oder eines Sprays eingesetzt. EPT, auch als Kombinationstherapie bekannt, kombiniert \u00d6strogen- und Progesterondosen.<\/p>\n<p>Die Art der Hormonbehandlung h\u00e4ngt von mehreren Faktoren ab, unter anderem davon, ob sich die Patientin einer Hysterektomie unterzogen hat. Bei Frauen mit einer Geb\u00e4rmutter wird eine Kombination aus \u00d6strogen und Progesteron eingesetzt, um das Risiko f\u00fcr Geb\u00e4rmutterkrebs zu verringern. Man geht jedoch davon aus, dass die alleinige Behandlung mit \u00d6strogen im Vergleich zur Kombinationstherapie weniger langfristige Risiken birgt.<\/p>\n<p>Im sp\u00e4testen <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">lernen<\/a>, ver\u00f6ffentlicht in der Fachzeitschrift \u201eHypertension\u201c der American Heart Association, untersuchten Forscher Daten von mehr als 112.000 Frauen, die 45 Jahre oder \u00e4lter waren, nachdem sie ein Jahr lang eine reine \u00d6strogen-Hormontherapie erhalten hatten.<\/p>\n<p>Forscher untersuchten den Zusammenhang zwischen der Art der \u00d6strogenverabreichung \u2013 orale, transdermale und vaginale Anwendung \u2013 und dem Risiko, an Bluthochdruck zu erkranken.<\/p>\n<p>Entsprechend der <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">Forscher<\/a>, erh\u00f6hte die Einnahme von oralem \u00d6strogen das Risiko f\u00fcr Bluthochdruck um 14% im Vergleich zur Hormonbehandlung mit transdermalen \u00d6strogencremes. Das Risiko von \u00d6strogenpillen betrug 19% im Vergleich zur Verwendung von vaginalen \u00d6strogencremes oder -z\u00e4pfchen.<\/p>\n<p>\u201eWir wissen, dass oral eingenommene \u00d6strogene \u00fcber die Leber verstoffwechselt werden, und dies ist mit einer Zunahme von Faktoren verbunden, die zu einem h\u00f6heren Blutdruck f\u00fchren k\u00f6nnen\u201c, sagte Cindy Kalenga, die Hauptautorin der Studie.<\/p>\n<p>Das Forschungsteam stellte au\u00dferdem fest, dass die Einnahme von \u00d6strogen \u00fcber einen l\u00e4ngeren Zeitraum oder die Anwendung einer h\u00f6heren Dosis mit einem h\u00f6heren Risiko f\u00fcr Bluthochdruck verbunden war.<\/p>\n<p>&quot;Wir wissen das <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">postmenopausal<\/a> Frauen haben im Vergleich zu Frauen vor der Menopause ein erh\u00f6htes Risiko f\u00fcr Bluthochdruck. Dar\u00fcber hinaus haben fr\u00fchere Studien gezeigt, dass bestimmte Arten der Hormontherapie mit einer h\u00f6heren Rate an Herzerkrankungen verbunden sind. Wir haben uns entschieden, tiefer in die Faktoren einzutauchen, die mit der Hormontherapie in Zusammenhang stehen, etwa den Verabreichungsweg (oral vs. nicht oral) und die Art des \u00d6strogens, und wie sie den Blutdruck beeinflussen k\u00f6nnen\u201c, sagte Kalenga.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><picture class=\"mapping-embed\" width=\"736\" height=\"1103\"><source type=\"image\/webp\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 1100px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/jpeg\" media=\"(min-width: 768px)\" sizes=\"1000px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=1100&amp;f=189955a19a4d23ea5c30a53d2747a5fc 1100w\"><source type=\"image\/webp\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3 736w\"><source type=\"image\/jpeg\" media=\"(min-width: 480px)\" sizes=\"736px\" srcset=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg 736w\"><source type=\"image\/webp\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/jpeg\" media=\"(min-width: 0px)\" sizes=\"480px\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.jpg?w=480&amp;f=dc714cfa8dd45a72abe245cb2327a7ef 480w\"><source type=\"image\/webp\" srcset=\"https:\/\/d.medicaldaily.com\/en\/full\/458646\/adult.webp?w=736&amp;f=d6816be6d80ac5808bc62d279b7f11e3\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"adult\" width=\"736\" height=\"1103\" style=\"display:none\"><\/picture><\/div><figcaption class=\"caption\">\n<span class=\"cap\">Die Wechseljahre k\u00f6nnen alles verursachen, von Hitzewallungen bis hin zu Ged\u00e4chtnisverlust. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Ver\u00f6ffentlicht von Medicaldaily.com<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-hypertension-470012\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Frauen, die im Rahmen ihrer Hormontherapie in den Wechseljahren \u00d6strogentabletten einnehmen, haben ein h\u00f6heres Risiko, an Bluthochdruck zu erkranken, wie eine aktuelle Studie ergab.<\/p>\n<p>Wenn eine Frau in die Wechseljahre kommt, produzieren ihre Eierst\u00f6cke nicht mehr wie zuvor hohe Mengen an \u00d6strogen und Progesteron. Dieser pl\u00f6tzliche Hormonabfall verursacht verschiedene Beschwerden wie Hitzewallungen, Nachtschwei\u00df, Stimmungsschwankungen und Schlafst\u00f6rungen.<\/p>\n<p>Frauen in den Wechseljahren wird h\u00e4ufig eine Hormonersatztherapie empfohlen, um die Symptome zu lindern und das Risiko von Osteoporose und Herz-Kreislauf-Erkrankungen, die mit dem Hormonabfall einhergehen, zu verringern.<\/p>\n<p>Es gibt zwei Haupttypen von h<a rel=\"noopener nofollow\" href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/15245-hormone-therapy-for-menopause-symptoms\" target=\"_blank\">Ormon-Ersatztherapien<\/a> \u2013 \u00d6strogentherapie und \u00d6strogen-Progesteron\/Gestagen-Hormontherapie (EPT).<\/p>\n<p>Bei der \u00d6strogentherapie wird \u00d6strogen in Form einer Pille, eines Pflasters, einer Creme, eines Vaginalrings, eines Gels oder eines Sprays eingesetzt. EPT, auch als Kombinationstherapie bekannt, kombiniert \u00d6strogen- und Progesterondosen.<\/p>\n<p>Die Art der Hormonbehandlung h\u00e4ngt von mehreren Faktoren ab, unter anderem davon, ob sich die Patientin einer Hysterektomie unterzogen hat. Bei Frauen mit einer Geb\u00e4rmutter wird eine Kombination aus \u00d6strogen und Progesteron eingesetzt, um das Risiko f\u00fcr Geb\u00e4rmutterkrebs zu verringern. Man geht jedoch davon aus, dass die alleinige Behandlung mit \u00d6strogen im Vergleich zur Kombinationstherapie weniger langfristige Risiken birgt.<\/p>\n<p>Im sp\u00e4testen <a rel=\"noopener nofollow\" href=\"https:\/\/newsroom.heart.org\/news\/women-taking-oral-estrogen-hormones-may-have-increased-risk-of-high-blood-pressure\" target=\"_blank\">lernen<\/a>, ver\u00f6ffentlicht in der Fachzeitschrift \u201eHypertension\u201c der American Heart Association, untersuchten Forscher Daten von mehr als 112.000 Frauen, die 45 Jahre oder \u00e4lter waren, nachdem sie ein Jahr lang eine reine \u00d6strogen-Hormontherapie erhalten hatten.<\/p>\n<p>Forscher untersuchten den Zusammenhang zwischen der Art der \u00d6strogenverabreichung \u2013 orale, transdermale und vaginale Anwendung \u2013 und dem Risiko, an Bluthochdruck zu erkranken.<\/p>\n<p>Entsprechend der <a rel=\"noopener nofollow\" href=\"https:\/\/www.healthline.com\/health-news\/oral-estrogen-may-raise-your-risk-of-hypertension-by-19-compared-to-other-forms-of-hormone-replacement-therapy#What-the-study-suggests-about-the-link-between-HRT-and-high-blood-pressure\" target=\"_blank\">Forscher<\/a>, erh\u00f6hte die Einnahme von oralem \u00d6strogen das Risiko f\u00fcr Bluthochdruck um 14% im Vergleich zur Hormonbehandlung mit transdermalen \u00d6strogencremes. Das Risiko von \u00d6strogenpillen betrug 19% im Vergleich zur Verwendung von vaginalen \u00d6strogencremes oder -z\u00e4pfchen.<\/p>\n<p>\u201eWir wissen, dass oral eingenommene \u00d6strogene \u00fcber die Leber verstoffwechselt werden, und dies ist mit einer Zunahme von Faktoren verbunden, die zu einem h\u00f6heren Blutdruck f\u00fchren k\u00f6nnen\u201c, sagte Cindy Kalenga, die Hauptautorin der Studie.<\/p>\n<p>Das Forschungsteam stellte au\u00dferdem fest, dass die Einnahme von \u00d6strogen \u00fcber einen l\u00e4ngeren Zeitraum oder die Anwendung einer h\u00f6heren Dosis mit einem h\u00f6heren Risiko f\u00fcr Bluthochdruck verbunden war.<\/p>\n<p>&quot;Wir wissen das <a rel=\"nofollow\" href=\"https:\/\/www.medicaldaily.com\/can-menopausal-age-predict-alzheimers-risk-heres-what-study-says-469295\">postmenopausal<\/a> Frauen haben im Vergleich zu Frauen vor der Menopause ein erh\u00f6htes Risiko f\u00fcr Bluthochdruck. Dar\u00fcber hinaus haben fr\u00fchere Studien gezeigt, dass bestimmte Arten der Hormontherapie mit einer h\u00f6heren Rate an Herzerkrankungen verbunden sind. Wir haben uns entschieden, tiefer in die Faktoren einzutauchen, die mit der Hormontherapie in Zusammenhang stehen, etwa den Verabreichungsweg (oral vs. nicht oral) und die Art des \u00d6strogens, und wie sie den Blutdruck beeinflussen k\u00f6nnen\u201c, sagte Kalenga.<\/p>\n<figure class=\"imageBox\">\n<div class=\"innerBox\"><img loading=\"lazy\" decoding=\"async\" class=\"mapping-embed imgPhoto\" id=\"i458646\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" alt=\"adult\" width=\"736\" height=\"1103\"><\/div><figcaption class=\"caption\">\n<span class=\"cap\">Die Wechseljahre k\u00f6nnen alles verursachen, von Hitzewallungen bis hin zu Ged\u00e4chtnisverlust. <\/span><br \/>\n<span class=\"credit\">Pixabay<\/span><br \/>\n<\/figcaption><\/figure>\n<p>Ver\u00f6ffentlicht von Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8304,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8303","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/studie-zur-hormonersatztherapie-besagt-dass-die-einnahme-von-oralem-ostrogen-das-risiko-fur-bluthochdruck-erhoht\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.&quot;We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,&quot; said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.&quot;We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,&quot; Kalenga said. Menopause can cause everything from hot flashes to memory loss. Pixabay Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/studie-zur-hormonersatztherapie-besagt-dass-die-einnahme-von-oralem-ostrogen-das-risiko-fur-bluthochdruck-erhoht\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-06T06:32:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension\",\"datePublished\":\"2023-06-06T06:32:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\"},\"wordCount\":455,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"url\":\"https:\/\/urbancare.clinic\/hormone-replacement-therapy-study-says-taking-oral-estrogen-increases-risk-of-hypertension\/\",\"name\":\"Hormone Replacement Therapy: Study Says Taking Oral Estrogen Increases Risk Of Hypertension - 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Urban Care Clinic","og_description":"Women taking estrogen pills as part of their menopausal hormone therapy are at a greater risk of developing hypertension, a recent study has found.As a woman goes through menopause, her ovaries no longer produce high levels of estrogen and progesterone as before. This sudden drop in hormones causes several discomforts such as hot flashes, night sweats, mood swings and difficulty sleeping.Hormone replacement therapy is often recommended for menopausal women to relieve the symptoms, and to reduce the risk of osteoporosis and cardiovascular diseases associated with the drop in hormones.There are two main types of hormone replacement therapies \u2013 estrogen therapy and estrogen progesterone\/progestin hormone therapy (EPT).Estrogen therapy involves the use of estrogen in the form of a pill, patch, cream, vaginal ring, gel, or spray. EPT, also known as combination therapy, combines doses of estrogen and progesterone.The type of hormone treatment is decided based on several factors, including if the patient has undergone a hysterectomy. A combination of estrogen and progesterone is used in women with a uterus to reduce the risk of endometrial cancer. However, estrogen-alone treatment is believed to have fewer long-term risks compared to combination therapy.In the latest study, published in the American Heart Association journal Hypertension, researchers examined data from more than 112,000 women who were 45 years or older after they were put on estrogen-only hormone therapy for a year.Researchers examined the relationship between the method of estrogen administration \u2013 oral, transdermal and vaginal application \u2013 and the risk of developing hypertension.According to the researchers, taking oral estrogen increased the risk of high blood pressure by 14% when compared to hormone treatment using transdermal estrogen creams. The risk of estrogen pills was 19% in comparison with the use of vaginal estrogen creams or suppositories.\"We know estrogens ingested orally are metabolized through the liver, and this is associated with an increase in factors that can lead to higher blood pressure,\" said Cindy Kalenga, the lead author of the study.The research team also found that taking estrogen for an extended period or use of a higher dose was associated with a greater risk of high blood pressure.\"We know that post-menopausal women have an increased risk of high blood pressure when compared to pre-menopausal women, furthermore, previous studies have shown that specific types of hormone therapy have been associated with higher rates of heart disease. We chose to dive deeper into factors associated with hormone therapy, such as the route of administration (oral vs. non-oral) and type of estrogen, and how they may affect blood pressure,\" Kalenga said. Menopause can cause everything from hot flashes to memory loss. 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