{"id":8301,"date":"2023-06-05T09:24:37","date_gmt":"2023-06-05T06:24:37","guid":{"rendered":"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/"},"modified":"2023-06-05T09:24:37","modified_gmt":"2023-06-05T06:24:37","slug":"die-pubertat-konnte-der-beste-zeitpunkt-fur-die-behandlung-von-schizophrenie-autismus-sein","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/die-pubertat-konnte-der-beste-zeitpunkt-fur-die-behandlung-von-schizophrenie-autismus-sein\/","title":{"rendered":"Die Pubert\u00e4t k\u00f6nnte der beste Zeitpunkt zur Behandlung von Schizophrenie und Autismus sein"},"content":{"rendered":"

Wissenschaftler haben ein potenzielles Fenster zur Behandlung neuropsychiatrischer St\u00f6rungen identifiziert, die durch eine Dopamin-Dysfunktion verursacht werden.<\/p>\n

Die neueste Studie von Forschern der Universit\u00e4t Rochester hat ergeben, dass die Adoleszenz der beste Zeitpunkt f\u00fcr die Behandlung von Erkrankungen wie Schizophrenie und Autismus ist, die beide durch eine Funktionsst\u00f6rung des Dopaminsystems gekennzeichnet sind.<\/p>\n

Autistische Menschen haben niedrige Level<\/a> von Dopamin. Studien zeigen, dass dies ihre Motivation f\u00fcr soziale Interaktionen verringern k\u00f6nnte, da ihr Gehirn diese Aktivit\u00e4ten als nicht lohnend registriert.<\/p>\n

Bei schizophrenen Personen Dopaminspiegel<\/a> kann entweder zu hoch oder zu niedrig sein. Ein abnormaler Anstieg der Dopaminaktivit\u00e4t in bestimmten Teilen des Gehirns f\u00fchrt zu positiven Symptomen der Schizophrenie wie Halluzinationen oder Wahnvorstellungen. Positive Symptome beziehen sich auf Verhaltens- oder Gedanken\u00e4nderungen, nachdem eine Person eine Schizophrenie entwickelt.<\/p>\n

Wenn die Dopaminaktivit\u00e4t in bestimmten Teilen des Gehirns zu niedrig ist, kann dies bei schizophrenen Patienten auftreten Negativsymptome<\/a> und kognitive Symptome. Negative Symptome sind durch das Fehlen eines normalen Verhaltens gekennzeichnet, w\u00e4hrend kognitive Symptome Probleme mit der Konzentration und Aufmerksamkeit umfassen.<\/p>\n

Im sp\u00e4testen lernen<\/a>, stimulierten Forscher die leistungsschwachen Neuronenzellen, die bei M\u00e4usen Dopamin f\u00fcr den frontalen Kortex des Gehirns bereitstellen. Sie fanden heraus, dass die Aktivierung zur St\u00e4rkung des Schaltkreises beitr\u00e4gt, der f\u00fcr eine h\u00f6here kognitive Verarbeitung und Entscheidungsfindung unerl\u00e4sslich ist.<\/p>\n

In einer fr\u00fcheren Studie stellte das Team fest, dass der spezifische Arm des Dopaminsystems im Gehirn von Jugendlichen flexibler ist als bei Erwachsenen. Die neueste Studie legt nahe, dass dieses Fenster eine Gelegenheit f\u00fcr therapeutische Interventionen bietet.<\/p>\n

\u201eDie Entwicklung des Gehirns ist ein langwieriger Prozess, und viele neuronale Systeme haben kritische Fenster \u2013 Schl\u00fcsselzeiten, in denen Gehirnbereiche formbar sind und letzte Reifungsschritte durchlaufen.\u201c Indem wir diese Fenster identifizieren, k\u00f6nnen wir Interventionen auf diese Zeitr\u00e4ume ausrichten und m\u00f6glicherweise den Verlauf einer Krankheit \u00e4ndern, indem wir die durch diese St\u00f6rungen verursachten strukturellen und Verhaltensdefizite beheben.\u201c genannt<\/a> Rianne Stowell, Co-Erstautorin der Studie.<\/p>\n

Forscher glauben, dass die Entdeckung sie der Suche nach einem m\u00f6glichen Angriffspunkt f\u00fcr die Behandlung neuropsychiatrischer Erkrankungen einen Schritt n\u00e4her bringen wird.<\/p>\n

\u201eDiese Ergebnisse legen nahe, dass eine Erh\u00f6hung der Aktivit\u00e4t des dopaminergen Schaltkreises bei Jugendlichen bestehende Defizite im Schaltkreis beheben kann und dass dieser Effekt lang anhaltend sein kann, da diese Ver\u00e4nderungen bis ins Erwachsenenalter bestehen bleiben.\u201c Wenn wir die richtigen Entwicklungsfenster ansteuern und die Signale verstehen, die dabei im Spiel sind, k\u00f6nnen wir Behandlungen entwickeln, die den Verlauf dieser Hirnst\u00f6rungen ver\u00e4ndern\u201c, f\u00fcgte Stowell hinzu.<\/p>\n

\n
\"teenager\"<\/picture><\/div>
\nLaut einer Studie ist die Pubert\u00e4t die beste Zeit, um Erkrankungen wie Schizophrenie und Autismus zu behandeln.<\/span>
\nFoto mit freundlicher Genehmigung von Pexels<\/span>
\n<\/figcaption><\/figure>\n

Ver\u00f6ffentlicht von Medicaldaily.com<\/p>\n

Medizinische t\u00e4gliche Quelle<\/a><\/p>\n

","protected":false},"excerpt":{"rendered":"

Wissenschaftler haben ein potenzielles Fenster zur Behandlung neuropsychiatrischer St\u00f6rungen identifiziert, die durch eine Dopamin-Dysfunktion verursacht werden.<\/p>\n

Die neueste Studie von Forschern der Universit\u00e4t Rochester hat ergeben, dass die Adoleszenz der beste Zeitpunkt f\u00fcr die Behandlung von Erkrankungen wie Schizophrenie und Autismus ist, die beide durch eine Funktionsst\u00f6rung des Dopaminsystems gekennzeichnet sind.<\/p>\n

Autistische Menschen haben niedrige Level<\/a> von Dopamin. Studien zeigen, dass dies ihre Motivation f\u00fcr soziale Interaktionen verringern k\u00f6nnte, da ihr Gehirn diese Aktivit\u00e4ten als nicht lohnend registriert.<\/p>\n

Bei schizophrenen Personen Dopaminspiegel<\/a> kann entweder zu hoch oder zu niedrig sein. Ein abnormaler Anstieg der Dopaminaktivit\u00e4t in bestimmten Teilen des Gehirns f\u00fchrt zu positiven Symptomen der Schizophrenie wie Halluzinationen oder Wahnvorstellungen. Positive Symptome beziehen sich auf Verhaltens- oder Gedanken\u00e4nderungen, nachdem eine Person eine Schizophrenie entwickelt.<\/p>\n

Wenn die Dopaminaktivit\u00e4t in bestimmten Teilen des Gehirns zu niedrig ist, kann dies bei schizophrenen Patienten auftreten Negativsymptome<\/a> und kognitive Symptome. Negative Symptome sind durch das Fehlen eines normalen Verhaltens gekennzeichnet, w\u00e4hrend kognitive Symptome Probleme mit der Konzentration und Aufmerksamkeit umfassen.<\/p>\n

Im sp\u00e4testen lernen<\/a>, stimulierten Forscher die leistungsschwachen Neuronenzellen, die bei M\u00e4usen Dopamin f\u00fcr den frontalen Kortex des Gehirns bereitstellen. Sie fanden heraus, dass die Aktivierung zur St\u00e4rkung des Schaltkreises beitr\u00e4gt, der f\u00fcr eine h\u00f6here kognitive Verarbeitung und Entscheidungsfindung unerl\u00e4sslich ist.<\/p>\n

In einer fr\u00fcheren Studie stellte das Team fest, dass der spezifische Arm des Dopaminsystems im Gehirn von Jugendlichen flexibler ist als bei Erwachsenen. Die neueste Studie legt nahe, dass dieses Fenster eine Gelegenheit f\u00fcr therapeutische Interventionen bietet.<\/p>\n

\u201eDie Entwicklung des Gehirns ist ein langwieriger Prozess, und viele neuronale Systeme haben kritische Fenster \u2013 Schl\u00fcsselzeiten, in denen Gehirnbereiche formbar sind und letzte Reifungsschritte durchlaufen.\u201c Indem wir diese Fenster identifizieren, k\u00f6nnen wir Interventionen auf diese Zeitr\u00e4ume ausrichten und m\u00f6glicherweise den Verlauf einer Krankheit \u00e4ndern, indem wir die durch diese St\u00f6rungen verursachten strukturellen und Verhaltensdefizite beheben.\u201c genannt<\/a> Rianne Stowell, Co-Erstautorin der Studie.<\/p>\n

Forscher glauben, dass die Entdeckung sie der Suche nach einem m\u00f6glichen Angriffspunkt f\u00fcr die Behandlung neuropsychiatrischer Erkrankungen einen Schritt n\u00e4her bringen wird.<\/p>\n

\u201eDiese Ergebnisse legen nahe, dass eine Erh\u00f6hung der Aktivit\u00e4t des dopaminergen Schaltkreises bei Jugendlichen bestehende Defizite im Schaltkreis beheben kann und dass dieser Effekt lang anhaltend sein kann, da diese Ver\u00e4nderungen bis ins Erwachsenenalter bestehen bleiben.\u201c Wenn wir die richtigen Entwicklungsfenster ansteuern und die Signale verstehen, die dabei im Spiel sind, k\u00f6nnen wir Behandlungen entwickeln, die den Verlauf dieser Hirnst\u00f6rungen ver\u00e4ndern\u201c, f\u00fcgte Stowell hinzu.<\/p>\n

\n
\"teenager\"<\/div>
\nLaut einer Studie ist die Pubert\u00e4t die beste Zeit, um Erkrankungen wie Schizophrenie und Autismus zu behandeln.<\/span>
\nFoto mit freundlicher Genehmigung von Pexels<\/span>
\n<\/figcaption><\/figure>\n

Ver\u00f6ffentlicht von Medicaldaily.com<\/p>","protected":false},"author":2,"featured_media":8302,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[],"class_list":["post-8301","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"\nAdolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/die-pubertat-konnte-der-beste-zeitpunkt-fur-die-behandlung-von-schizophrenie-autismus-sein\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Scientists have identified a potential window for treating neuropsychiatric disorders caused by dopamine dysfunction.The latest study by researchers from the University of Rochester has found that adolescence is the best time to treat conditions such as schizophrenia and autism, both characterized by dysfunctioning of the dopamine system.Autistic individuals have low levels of dopamine. Studies show this could reduce their motivation to pursue social interactions as their brains register these activities as not rewarding.In schizophrenic individuals, dopamine levels can either be too high or too low. Abnormal increase in dopamine activity in certain parts of the brain causes positive symptoms of schizophrenia such as hallucinations or delusions. Positive symptoms refer to changes in behaviors or thoughts after an individual develops schizophrenia.When dopamine activity is too low in certain parts of the brain, schizophrenic patients can show negative symptoms and cognitive symptoms. Negative symptoms are marked by the absence of normal behavior, while cognitive symptoms include issues with focusing and attention.In the latest study, researchers stimulated the underperforming neuron cells that provide dopamine to the frontal cortex of the brain in mice. They found that the activation helps in strengthening the circuit essential for higher cognitive processing and decision-making.In a previous study, the team identified the specific arm of the dopamine system was more flexible in the adolescent brain than in adults. The latest study suggests this window is an opportunity for therapeutic intervention."Brain development is a lengthy process, and many neuronal systems have critical windows \u2013 key times when brain areas are malleable and undergoing final maturation steps. By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders," said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders."These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders," Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. Photo Courtesy of Pexels Published by Medicaldaily.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/die-pubertat-konnte-der-beste-zeitpunkt-fur-die-behandlung-von-schizophrenie-autismus-sein\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-05T06:24:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\/\/urbancare.clinic\/#\/schema\/person\/f286c4d84be896d302aceda3ed7e789c\"},\"headline\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism\",\"datePublished\":\"2023-06-05T06:24:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\"},\"wordCount\":420,\"publisher\":{\"@id\":\"https:\/\/urbancare.clinic\/#organization\"},\"image\":{\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/06\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism.jpg\",\"articleSection\":[\"Medical Daily\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"url\":\"https:\/\/urbancare.clinic\/adolescence-could-be-the-best-time-to-treat-schizophrenia-autism\/\",\"name\":\"Adolescence Could Be The Best Time To Treat Schizophrenia, Autism - 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Studies show this could reduce their motivation to pursue social interactions as their brains register these activities as not rewarding.In schizophrenic individuals, dopamine levels can either be too high or too low. Abnormal increase in dopamine activity in certain parts of the brain causes positive symptoms of schizophrenia such as hallucinations or delusions. Positive symptoms refer to changes in behaviors or thoughts after an individual develops schizophrenia.When dopamine activity is too low in certain parts of the brain, schizophrenic patients can show negative symptoms and cognitive symptoms. Negative symptoms are marked by the absence of normal behavior, while cognitive symptoms include issues with focusing and attention.In the latest study, researchers stimulated the underperforming neuron cells that provide dopamine to the frontal cortex of the brain in mice. They found that the activation helps in strengthening the circuit essential for higher cognitive processing and decision-making.In a previous study, the team identified the specific arm of the dopamine system was more flexible in the adolescent brain than in adults. The latest study suggests this window is an opportunity for therapeutic intervention.\"Brain development is a lengthy process, and many neuronal systems have critical windows \u2013 key times when brain areas are malleable and undergoing final maturation steps. By identifying these windows, we can target interventions to these time periods and possibly change the course of a disease by rescuing the structural and behavioral deficits caused by these disorders,\" said Rianne Stowell, co-first author of the study.Researchers believe the discovery will take them a step closer to finding a possible target for treating neuropsychiatric disorders.\"These findings suggest that increasing the activity of the adolescent dopaminergic circuitry can rescue existing deficits in the circuit and that this effect can be long-lasting as these changes persist into adulthood. If we can target the right windows in development and understand the signals at play, we can develop treatments that change the course of these brain disorders,\" Stowell added. Adolescence is the best time to treat conditions such as schizophrenia and autism, a study has found. 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