{"id":7523,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/uremic-leontiasis-ossea\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"uramische-leontiasis-ossea","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/uremic-leontiasis-ossea\/","title":{"rendered":"Ur\u00e4mische Leontiasis ossea"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<p id=\"p-1\">Ein 40-j\u00e4hriger Mann stellte sich mit einer seit 5 Jahren bestehenden Vorgeschichte fortschreitender Gesichtsver\u00e4nderungen und Schwierigkeiten beim Kauen vor. Er litt an einer chronischen Nierenerkrankung und wurde im Alter von 17 Jahren dialysepflichtig. Bei der Untersuchung wurde ein hervorstehender Oberkiefer mit Malokklusion festgestellt. Sein intakter Parathormonspiegel \u00fcberstieg 2500 pg\/ml (Referenzbereich: 15,6\u201368,3). Die CT des Gesichts zeigte eine Verdickung des Sch\u00e4delknochens, \u2026 <\/p>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e37?rss=1\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>Ein 40-j\u00e4hriger Mann stellte sich vor und litt seit 5 Jahren an fortschreitenden Ver\u00e4nderungen im Gesicht und Schwierigkeiten beim Kauen. Er litt an einer chronischen Nierenerkrankung und war im Alter von 17 Jahren dialysepflichtig. Bei der Untersuchung fiel ein vorstehender Oberkiefer mit Fehlbiss auf. Sein intakter Parathormonspiegel lag \u00fcber 2500 pg\/ml (Referenzbereich: 15,6\u201368,3). Die CT des Gesichts zeigte eine Verdickung des Sch\u00e4delknochens und ein \u00dcberwachstum des Ober- und Unterkiefers (<cross-ref type=\"fig\" refid=\"F1\">Abbildung 1A,B<\/cross-ref>). In der Sch\u00e4deldecke war ein salz- und pfefferartiges Erscheinungsbild zu sehen (<cross-ref type=\"fig\" refid=\"F1\">Abbildung 1B<\/cross-ref>, Pfeil). Diese Befunde stimmten mit der ur\u00e4mischen Leontiasis ossea \u00fcberein, einer seltenen und schweren Form der renalen Osteodystrophie aufgrund von Hyperparathyreoidismus.<cross-ref type=\"bib\" refid=\"R1\">1<\/cross-ref><\/p>\n<p>Leontiasis ossea \u2013 auch als L\u00f6wengesicht bekannt \u2013 f\u00fchrt nicht nur zur Entstellung des Patienten, sondern die Knochenausdehnung kann auch die umliegenden Gesichtsstrukturen wie die Nasen- und Mundh\u00f6hle zusammendr\u00fccken, was zu Atemwegsobstruktionen, Dysarthrie und Dysphagie f\u00fchren kann (<cross-ref type=\"fig\" refid=\"F1\">Abbildung 1C<\/cross-ref>,&#8230;<\/p>","protected":false},"author":2,"featured_media":7524,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Uremic leontiasis ossea - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/uramische-leontiasis-ossea\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Uremic leontiasis ossea - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"A 40-year-old man presented with a 5-year history of progressive facial changes and difficulty chewing. He had a history of chronic kidney disease and became dialysis dependent at the age of 17. On examination, protruding upper jaw with malocclusion was observed. His intact parathyroid hormone level exceeded 2500 pg\/mL (reference range: 15.6&ndash;68.3). CT of the face showed cranial bone thickening, and overgrowth of the maxilla and mandible (figure 1A,B). Salt and pepper appearance was seen in the calvaria (figure 1B, arrow). These findings were consistent with uremic leontiasis ossea, a rare and severe form of renal osteodystrophy due to hyperparathyroidism.1 Leontiasis ossea&mdash;also known as lion face&mdash;results in not only disfigurement of the patient, but also the bony expansion may also compress the nearby facial structures, such as the nasal and oral cavity, leading to airway obstruction, dysarthria and dysphagia (figure 1C,...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/urbancare.clinic\/de\/uramische-leontiasis-ossea\/\" \/>\n<meta property=\"og:site_name\" content=\"Urban Care Clinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/urbancarezanzibar\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-22T10:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/02\/uremic-leontiasis-ossea.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Urban Care Clinic\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Urban Care Clinic\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"author\":{\"name\":\"Urban Care Clinic\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#\\\/schema\\\/person\\\/a304a61bcf298680ee41e2e9ae193930\"},\"headline\":\"Uremic leontiasis ossea\",\"datePublished\":\"2022-11-22T10:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\"},\"wordCount\":64,\"publisher\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/urbancare.clinic\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/uremic-leontiasis-ossea.jpg\",\"articleSection\":[\"Research Articles\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"url\":\"https:\\\/\\\/urbancare.clinic\\\/uremic-leontiasis-ossea\\\/\",\"name\":\"Uremic leontiasis ossea - 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