{"id":7487,"date":"2022-11-22T13:00:22","date_gmt":"2022-11-22T10:00:22","guid":{"rendered":"https:\/\/urbancare.clinic\/multiple-fibroadenomas-of-the-breasts-a-cause-of-monthly-chest-pain\/"},"modified":"2022-11-22T13:00:22","modified_gmt":"2022-11-22T10:00:22","slug":"multiple-fibroadenome-der-bruste-sind-eine-ursache-fur-monatliche-brustschmerzen","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/multiple-fibroadenomas-of-the-breasts-a-cause-of-monthly-chest-pain\/","title":{"rendered":"Multiple Fibroadenome der Br\u00fcste: eine Ursache f\u00fcr monatliche Brustschmerzen"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/multiple-fibroadenomas-of-the-breasts-a-cause-of-monthly-chest-pain.jpg\" class=\"ff-og-image-inserted\" style=\"display:none\"><\/div>\n<p><span class=\"highwire-journal-article-marker-start\"><\/span><\/p>\n<div class=\"section\" id=\"sec-1\" readability=\"18\">\n<h2 class>Klinisches Bild<\/h2>\n<p id=\"p-1\">Eine 35-j\u00e4hrige Frau berichtete von anhaltenden beidseitigen Brustschmerzen, die mehrere Jahre anhielten, durch Vibration oder Sch\u00fctteln verst\u00e4rkt wurden und w\u00e4hrend der Menstruation am st\u00e4rksten waren. Die Schmerzen schr\u00e4nkten ihre t\u00e4glichen Aktivit\u00e4ten ein. Die k\u00f6rperliche Untersuchung ergab in beiden Br\u00fcsten Massen, die schroffen Felsen \u00e4hnelten. Ihre medizinische und famili\u00e4re Vorgeschichte war unauff\u00e4llig und sie erhielt keine Medikamente.<\/p>\n<p id=\"p-2\">Die Ultraschalluntersuchung ergab mehr als 100 ovale, gut umschriebene Tumoren mit einer Gr\u00f6\u00dfe von jeweils 5\u201330 mm. Jede Brust war 200\u00d7200\u00d760 mm gro\u00df. Die kontrastmittelverst\u00e4rkte MRT zeigte bei dynamischer, schrittweiser Kontrastmittelaufnahme mehrere Tumoren in der gesamten Brust und \u2026 <\/p>\n<\/div>\n<p><span class=\"highwire-journal-article-marker-end\"><\/span><a href=\"http:\/\/pmj.bmj.com\/cgi\/content\/short\/98\/1166\/e28?rss=1\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p><sec id=\"s1\"><st>Klinisches Bild<\/st> <\/p>\n<p>Eine 35-j\u00e4hrige Frau berichtete von anhaltenden beidseitigen Brustschmerzen, die mehrere Jahre anhielten, durch Vibration oder Sch\u00fctteln verst\u00e4rkt wurden und w\u00e4hrend der Menstruation am st\u00e4rksten waren. Die Schmerzen schr\u00e4nkten ihre t\u00e4glichen Aktivit\u00e4ten ein. Die k\u00f6rperliche Untersuchung ergab in beiden Br\u00fcsten Massen, die schroffen Felsen \u00e4hnelten. Ihre medizinische und famili\u00e4re Vorgeschichte war unauff\u00e4llig und sie erhielt keine Medikamente.<\/p>\n<p>Die Ultraschalluntersuchung ergab mehr als 100 ovale, klar abgegrenzte Tumoren von jeweils 5\u201330 mm. Jede Brust war 200<font face=\"arial,helvetica\">X<\/font>200<font face=\"arial,helvetica\">X<\/font>60 mm. Die kontrastmittelverst\u00e4rkte MRT zeigte mehrere Tumoren in der gesamten Brust bei dynamischer schrittweiser Kontrastverst\u00e4rkung und ohne fr\u00fchzeitiges Auswaschen (<cross-ref type=\"fig\" refid=\"F1\">Abbildung 1<\/cross-ref>). Biopsien ergaben Fibroadenome. Daher wurden ihre Schmerzen diesen multiplen Fibroadenomen zugeschrieben.<\/p>\n<p>Eine konservative Behandlung mit niedrig dosiertem \u00d6strogen und Progesteron (zun\u00e4chst Norethisteron und Ethinylestradiol, sp\u00e4ter Dienogest) war wirkungslos. Tamoxifen sollte das \u00d6strogen unterdr\u00fccken. Aufgrund des Risikos, eine b\u00f6sartige Erkrankung zu \u00fcbersehen, des Nichtansprechens auf die konservative Behandlung und des Wunsches der Patientin f\u00fchrten wir jedoch eine beidseitige Mastektomie mit Haut-Areola-Transplantation durch. Die histopathologische Untersuchung zeigte\u2026<\/p>","protected":false},"author":2,"featured_media":7488,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/multiple-fibroadenomas-of-the-breasts-a-cause-of-monthly-chest-pain.jpg","fifu_image_alt":"","footnotes":""},"categories":[185],"tags":[],"class_list":["post-7487","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-medical-articles"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multiple fibroadenomas of the breasts: a cause of monthly chest pain - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/urbancare.clinic\/de\/multiple-fibroadenome-der-bruste-sind-eine-ursache-fur-monatliche-brustschmerzen\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multiple fibroadenomas of the breasts: a cause of monthly chest pain - Urban Care Clinic\" \/>\n<meta property=\"og:description\" content=\"Clinical image A 35-year-old woman reported of continuous bilateral chest pain lasting several years, aggravated by vibration or shaking and most intense during menstruation. The pain limited her daily activities. Physical examination revealed masses resembling rugged rocks in both breasts. Her medical and family histories were unremarkable, and she received no medication. Ultrasonography revealed more than 100 oval-shaped, well-circumscribed tumours, each 5&ndash;30 mm. Each breast was 200x200x60 mm. Contrast-enhanced MRI revealed multiple tumours throughout the breasts on dynamic gradual enhancement and no early washout (figure 1). Biopsies revealed fibroadenomas. Therefore, her pain was attributed to these multiple fibroadenomas. Conservative management with low-dose oestrogen and progesterone (norethisterone and ethinylestradiol initially, and dienogest subsequently) was ineffective. Tamoxifen was planned to suppress oestrogen; however, based on the risk of overlooking malignancy, the nonresponse to conservative treatment, and the patient&#039;s desire, we performed bilateral mastectomy with skin areola grafting. 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The pain limited her daily activities. Physical examination revealed masses resembling rugged rocks in both breasts. Her medical and family histories were unremarkable, and she received no medication. Ultrasonography revealed more than 100 oval-shaped, well-circumscribed tumours, each 5&ndash;30 mm. Each breast was 200x200x60 mm. Contrast-enhanced MRI revealed multiple tumours throughout the breasts on dynamic gradual enhancement and no early washout (figure 1). Biopsies revealed fibroadenomas. Therefore, her pain was attributed to these multiple fibroadenomas. Conservative management with low-dose oestrogen and progesterone (norethisterone and ethinylestradiol initially, and dienogest subsequently) was ineffective. Tamoxifen was planned to suppress oestrogen; however, based on the risk of overlooking malignancy, the nonresponse to conservative treatment, and the patient's desire, we performed bilateral mastectomy with skin areola grafting. 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