{"id":7483,"date":"2023-01-26T13:13:23","date_gmt":"2023-01-26T10:13:23","guid":{"rendered":"https:\/\/urbancare.clinic\/this-cancer-drug-can-increase-longevity-study-finds\/"},"modified":"2023-05-23T17:38:27","modified_gmt":"2023-05-23T14:38:27","slug":"studienergebnisse-zeigen-dass-dieses-krebsmedikament-die-lebenserwartung-verlangern-kann","status":"publish","type":"post","link":"https:\/\/urbancare.clinic\/de\/this-cancer-drug-can-increase-longevity-study-finds\/","title":{"rendered":"Dieses Krebsmedikament kann laut Studie die Lebenserwartung verl\u00e4ngern"},"content":{"rendered":"<div><img decoding=\"async\" src=\"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/this-cancer-drug-can-increase-longevity-study-finds.jpg\" class=\"ff-og-image-inserted\"  style=\"display:none\"><\/div>\n<p>Eine neue Studie hat ergeben, dass ein bestimmtes Krebsmedikament die Lebensspanne verl\u00e4ngern kann. F\u00fcr die Wissenschaftler im Wettlauf mit der Zeit ist die Entdeckung ein echter Gewinn.<\/p>\n<p>Die Studie, ver\u00f6ffentlicht in der Zeitschrift <a href=\"https:\/\/dx.doi.org\/10.1038\/s43587-022-00349-y\" rel=\"nofollow noopener\" target=\"_blank\">Alterung in der Natur<\/a>zeigten, dass eine Langzeitbehandlung gesunder M\u00e4use ab mittlerem Alter (ein Jahr) mit einem Krebsmedikament deren Lebenserwartung um durchschnittlich 10% verl\u00e4ngern kann \u2013 also etwa drei Jahre.<\/p>\n<p>In der von Forschern der University of Auckland durchgef\u00fchrten Studie wurden die M\u00e4use in zwei Gruppen eingeteilt. Beide Gruppen erhielten die gleiche Di\u00e4t, wobei der Mahlzeit der Testgruppe zus\u00e4tzlich ein Medikament namens Alpelisib hinzugef\u00fcgt wurde. Die Studie ergab, dass die M\u00e4use, denen die wirkstoffhaltige Di\u00e4t verabreicht wurde, l\u00e4nger lebten und auch im Alter eine verbesserte Koordination und Kraft zeigten.<\/p>\n<p>\u201eBeim Altern geht es nicht nur um die Lebensdauer, sondern auch um die Lebensqualit\u00e4t\u201c, sagte der Forscher Dr. Chris Hedges <a href=\"https:\/\/medicalxpress.com\/news\/2023-01-scientists-drug-lifespan.html\" rel=\"nofollow noopener\" target=\"_blank\">MedicalXpress<\/a>. \u201eDeshalb waren wir erfreut, dass diese medikament\u00f6se Behandlung nicht nur die Lebenserwartung der M\u00e4use erh\u00f6hte, sondern auch viele Anzeichen eines ges\u00fcnderen Alterns zeigte. Wir arbeiten jetzt daran zu verstehen, wie das passiert.\u201c<\/p>\n<div id=\"dfp-ad-oop2\" class=\"dfp-tag-wrapper\"> <\/div>\n<p>Allerdings warnten die Forscher davor, zu viel aus den Ergebnissen zu machen. Es ist zu beachten, dass die mit dem Medikament behandelten M\u00e4use auch einige negative Anzeichen des Alterns aufwiesen, wie beispielsweise eine geringere Knochenmasse.<\/p>\n<p>\u201eWir schlagen nicht vor, dass irgendjemand dieses Medikament langfristig einnehmen sollte, um die Lebensspanne zu verl\u00e4ngern, da es einige Nebenwirkungen gibt. Diese Arbeit identifiziert jedoch f\u00fcr das Altern entscheidende Mechanismen, die f\u00fcr unsere langfristigen Bem\u00fchungen zur Verl\u00e4ngerung der Lebens- und Gesundheitsspanne von Nutzen sein werden\u201c, erkl\u00e4rte der leitende Forscher, Associate Professor Troy Merry.<\/p>\n<p>\u201eEs schl\u00e4gt auch eine Reihe m\u00f6glicher Wege vor, wie kurzfristige Behandlungen mit diesem Medikament zur Behandlung bestimmter Stoffwechselerkrankungen eingesetzt werden k\u00f6nnten, und wir verfolgen dies jetzt\u201c, f\u00fcgte Merry hinzu.<\/p>\n<p>Das Medikament Alpelisib zielt auf ein Enzym namens PI-3-Kinase ab. Laut Professor Peter Shepherd arbeiten sie seit mehr als zwei Jahrzehnten an der Entwicklung von Medikamenten, die auf die PI-3-Kinase abzielen. Dies liegt vor allem daran, dass bei vielen Krebsarten eine \u00fcberm\u00e4\u00dfige Aktivierung dieses Signalwegs beobachtet wurde.<\/p>\n<p>\u201eDeshalb ist es gro\u00dfartig zu sehen, dass diese Medikamente m\u00f6glicherweise auch in anderen Bereichen Anwendung finden und neue Mechanismen aufdecken, die zu altersbedingten Krankheiten beitragen. Es zeigt auch den Wert einer langfristigen Investition in die Forschung in Bereichen wie diesem\u201c, sagte Shepherd laut der Verkaufsstelle.<\/p>\n<p>Eine andere aktuelle Studie hat herausgefunden, dass es eine gro\u00dfartige M\u00f6glichkeit ist, das Altern umzukehren<a href=\"https:\/\/www.medicaldaily.com\/ultrasound-therapy-can-awaken-zombie-cells-and-reverse-aging-study-finds-467818\"> \u201eZombie\u201c-Zellen mit Ultraschallwellen zappen<\/a>S. Nach erfolgreichen Experimenten an \u00e4lteren M\u00e4usen planen die Forscher nun eine klinische Studie, um die Sicherheit und Wirksamkeit der Technik am Menschen zu \u00fcberpr\u00fcfen. \u201e&#039;Ist das zu sch\u00f6n um wahr zu sein?&#039; ist die Frage, die ich oft stelle. Wir untersuchen alle Aspekte, um zu sehen, ob es wirklich funktioniert\u201c, sagte Hauptautor Professor Michael Sheetz von der University of Texas.<\/p>\n<p><a href=\"https:\/\/www.medicaldaily.com\/cancer-drug-can-increase-longevity-study-finds-467851?utm_source=Public&#038;utm_medium=Feed&#038;utm_campaign=Distribution\">Medizinische t\u00e4gliche Quelle<\/a><\/p>\n<p>","protected":false},"excerpt":{"rendered":"<p>\u201eBeim Altern geht es nicht nur um die Lebensdauer, sondern auch um die Lebensqualit\u00e4t\u201c, sagte der Forscher Dr. Chris Hedges.<\/p>","protected":false},"author":2,"featured_media":7484,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"page_builder":"","fifu_image_url":"https:\/\/urbancare.clinic\/wp-content\/uploads\/2023\/01\/this-cancer-drug-can-increase-longevity-study-finds.jpg","fifu_image_alt":"","footnotes":""},"categories":[27],"tags":[150],"class_list":["post-7483","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>This Cancer Drug Can Increase Longevity, Study Finds - Urban Care Clinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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